scholarly journals Knowledge, attitudes, and perceptions on genetically modified mosquitoes: Case for sterile mosquito release in Grenada

2017 ◽  
Vol 3 (1) ◽  
pp. 57
Author(s):  
Anjali Ghodasara ◽  
Marisa Deliso ◽  
Satesh Bidaisee

This study assessed knowledge, attitudes and perceptions of various stakeholders in Grenada regarding genetically modified organisms and the release of genetically modified mosquitoes. The study adopted a cross sectional design with a study population that comprised of members from seven stakeholder groups of civil society in Grenada. The sample population was obtained through a snowballing strategy and data collection for the study consisted of a semi-structured interview. Data was managed through the collection and reviewing of data from transcribed interview notes, as well as observations and interpretations made during the field collection. Interview recordings were analyzed to identify emerging themes. These themes were ranked according to the frequency with which they appeared, and main concepts identified by linking related themes. Most groups supported the use of genetically modified mosquitoes against Zika, but there were several varying concerns, including environmental worries and the impact of these organisms on humans. Many questioned the characteristics of Zika itself, and some believed Zika is a man-made virus created in a lab. Others doubted the link of Zika virus to microcephaly and other birth defects, and some were unsure if Zika virus is transmitted by mosquitoes. There is a wide range of differing knowledge, attitudes, and perceptions towards genetically modifying technology in general and towards mosquitoes in response to Zika.

Author(s):  
Nomfundo F. Moroe ◽  
Katijah Khoza-Shangase

Background: Few South African studies have been published on the impact of tinnitus on quality of life of tinnitus sufferers, although evidence suggests that a large portion of the general population suffers from tinnitus.Objectives: The current study aimed at describing the effects of tinnitus on the quality of life of the participants as measured by the Tinnitus Handicap Inventory (THI).Method: In a cross-sectional descriptive study design, 27 participants took part in the study by completing a self-administered THI questionnaire and participating in a semi-structured interview. Descriptive and inferential statistics were used to analyse the data. Descriptively, content analysis was used to organise and convey results from the interviews.Results: Participants reported a wide range of perceived disability on the THI. Results ranged from mild to catastrophic, with functional disability being most prominent in all participants, although there were differences when results were analysed according to gender. There was an association between gender and the type of perceived disability, although this was statistically non-significant (p > 0.05). Only 26% of the participants reported no effect on occupational performance and quality of life, with the remainder of the participants reporting a significant effect. Limited effective management strategies were reported to have been implemented – a significant implication for the audiologists.Conclusion: The results have implications for audiologists as they suggest that audiologists should take a detailed case history to determine the extent to which tinnitus affects the individual. Furthermore, audiologists should administer a scale such as the THI in the management of tinnitus.


Author(s):  
Behrad Pourmohammadi ◽  
Ahad Heydari ◽  
Farin Fatemi ◽  
Ali Modarresi

Abstract Objectives: Iran is exposed to a wide range of natural and man-made hazards. Health-care facilities can play a significant role in providing life-saving measures in the minutes and hours immediately following the impact or exposure. The aim of this study was to determine the preparedness of health-care facilities in disasters and emergencies. Methods: This cross-sectional study was conducted in Damghan, Semnan Province, in 2019. The samples consisted of all the 11 health-care facilities located in Damghan County. A developed checklist was used to collect the data, including 272 questions in 4 sections: understanding threatening hazards, functional, structural, and nonstructural vulnerability of health-care facilities. The data were analyzed using SPSS 21. Results: The results revealed that the health-care facilities were exposed to 22 different natural and man-made hazards throughout the county. The total level of preparedness of the health-care centers under assessment was 45.8%. The average functional, structural, and nonstructural vulnerability was assessed at 49.3%, 31.6%, and 56.4%, respectively. Conclusions: Conducting mitigation measures is necessary for promoting the functional and structural preparedness. Disaster educational programs and exercises are recommended among the health staff in health-care facilities.


Author(s):  
Jourdan Witt

Advancements in synthetic biology have led to the use of genetically modified organisms in research and industrial fields. Bacteria were one of the first organisms to be genetically engineered due to their fast growth and simple genetics, and have emerged as a major scientific and commercial interest. For instance, modified commensal bacteria can be used as an oral delivery vector of therapeutics, or as probiotics to target specific pathogens in the gastrointestinal tract. The impact of the release of pathogens used in research or vaccine development could be catastrophic to the environment and public health. In addition, there is growing concern about using genetically modified organisms in open systems, as there is a possibility for unintentional proliferation into natural environments. Therefore, is imperative that the environmental safety of genetically modified organisms are addressed, and that adequate biocontainment mechanisms are developed.


Author(s):  
Wenhuan Sun ◽  
Jason Paulovich ◽  
Victoria Webster-Wood

Abstract Electrochemically Aligned Collagen (ELAC) threads fabricated by the isoelectric focusing (IF) of collagen have previously shown potential in tissue engineering and more recently in the fabrication of biohybrid robot structures. For applications in biohybrid robotics, ELAC structures are needed that are both robust and compliant enough to facilitate muscle actuation. However, studies on the effects of IF parameters, and the interactions of such fabrication parameters, on the mechanical and geometric properties of resulting ELAC threads have not been previously found in literature. Understanding the impact of these manufacturing parameters on the material properties is critical to facilitate biohybrid robot design. In this study, the effects of IF duration, IF voltage, and collagen solution concentration were investigated and showed statistically significant effects on adjusting ELAC properties via single-factor experiments. The interactions between parameters exhibited significant joint effects on ELAC property tuning through two-factor experiments. Scanning electron microscopy and 2,4,6-trinitrobenzenesulfonic assays revealed the correlation between high mechanical properties and a combination of low porosity and high degree of crosslinking. By simply tuning IF parameters without changing other fabrication steps, such as crosslinker concentration, ELAC threads with a wide range of mechanical and geometric properties were fabricated. The average tensile modulus of the resulting ELAC threads ranged from 198±90 to 758±138 MPa. The average cross-sectional area ranged from 7756±1000 to 1775±457 µm2. The resultant mapping between IF parameters and ELAC thread properties enabled the production of strong and flexible threads with customizable properties.


2021 ◽  
Vol 104 (2) ◽  
pp. 252-259

Objective: To explore the associations of characteristics of the cluster environment with new psychoactive substances (NPS) use in Thailand. Materials and Methods: A cross-sectional study was done on 30,411 Thai people, stratified in multi-stage cluster sampling. Trained interviewers conducted a semi-structured interview in 2016. A multilevel binary logistic regression model was employed to estimate the effects of the cluster environment on the NPS use. Results: NPS was widely used. The past month prevalence was 13.6%, and habitual use was 4.4%. Clustering significantly affects the spread of NPS use. Controlling for cluster effects, a likelihood of current NPS use was associated with elementary education, occupation, and reported health problems. While a higher likelihood of habitual NPS use was associated with elementary education, employed, and perceived mental health problem. Conclusion: NPS use was influenced by characteristics of the cluster environment. Therefore, demand reduction strategies should be designed based on a consideration of the impact of cluster context on NPS use behaviors. Keywords: Cluster effect, New psychoactive substance, NPS, Thailand


2019 ◽  
Vol 43 (6) ◽  
pp. 587-631 ◽  
Author(s):  
Blaise Gnimassoun

Regional integration in Africa is a subject of great interest, but its impact on income has not been studied sufficiently. Using cross-sectional and panel estimations, this article examines the impact of African integration on real per capita income in Africa. Accordingly, we consider intra-African trade and migration flows as quantitative measures reflecting the intensity of regional integration. To address the endogeneity concerns, we use a gravity-based, two-stage least-squares strategy. Our results show that, from a long-term perspective, African integration has not been strong enough to generate a positive, significant, and robust impact on real per capita income in Africa. However, it does appear to be significantly income-enhancing in the short and medium terms but only through intercountry migration. These results are robust to a wide range of specifications.


Author(s):  
Jonas Schreyögg

Since the 1980s policymakers have identified a wide range of policy interventions to improve hospital performance. Some of these have been initiated at the level of government, whereas others have taken the form of decisions made by individual hospitals but have been guided by regulatory or financial incentives. Studies investigating the impact that some of the most important of these interventions have had on hospital performance can be grouped into four different research streams. Among the research streams, the strongest evidence exists for the effects of privatization. Studies on this topic use longitudinal designs with control groups and have found robust increases in efficiency and financial performance. Evidence on the entry of hospitals into health systems and the effects of this on efficiency is similarly strong. Although the other three streams of research also contain well-conducted studies with valuable findings, they are predominantly cross-sectional in design and therefore cannot establish causation. While the effects of introducing DRG-based hospital payments and of specialization are largely unclear, vertical and horizontal cooperation probably have a positive effect on efficiency and financial performance. Lastly, the drivers of improved efficiency or financial performance are very different depending on the reform or intervention being investigated; however, reductions in the number of staff and improved bargaining power in purchasing stand out as being of particular importance. Several promising avenues for future investigation are identified. One of these is situated within a new area of research examining the link between changes in the prices of treatments and hospitals’ responses. As there is evidence of unintended effects, future studies should attempt to distinguish between changes in hospitals’ responses at the intensive margin (e.g., upcoding) versus the extensive margin (e.g., increase in admissions). When looking at the effects of entering into a health system and of privatizations, there is still considerable need for research. With privatizations, in particular, the underlying processes are not yet fully understood, and the potential trade-offs between increases in performance and changes in the quality of care have not been sufficiently examined. Lastly, there is substantial need for further papers in the areas of multi-institutional arrangements and cooperation, as well as specialization. In both research streams, natural experiments carried out using program evaluation design are lacking. One of the main challenges here, however, is that cooperation and specialization cannot be directly observed but rather must be constructed based on survey or administrative data.


2020 ◽  
Vol 42 (6) ◽  
pp. 747-775
Author(s):  
Ivanka Pjesivac ◽  
Marlit A. Hayslett ◽  
Matthew T. Binford

This study examined the framing of genetically modified organisms in two American newspapers, The New York Times and the Washington Post (2000-2016) and tested the impact of risk and opportunity framing on attitudes and behaviors regarding genetically modified organisms. The content analysis ( N = 165) showed that the two newspapers did not have a dominant frame type in their coverage. A randomized three-condition experiment ( N = 182) showed that the type of framing significantly affected individuals’ attitudes and was able to change them. The type of framing affected individuals’ behavioral intentions through postexposure attitudes but was not able to significantly affect actual behavior.


2020 ◽  
Vol 19 (1) ◽  
pp. 38-53
Author(s):  
Nelly Sierra Ospina ◽  
Sergio Lopera Medina

This study reports on the impact of international visiting faculty’s teaching experiences in the United States on their personal, professional, and intercultural development. It is based on the principles of qualitative research and can be described as a case study. Data collection involved a questionnaire, a written narrative, and a semi-structured interview with each of a number of teachers. Participants included a group of 22 visiting faculty. Three main categories, each of which can be subdivided into benefits and challenges, emerged from the analysis: intercultural matters, professional matters, and personal matters. A wide range of benefits was identified, suggesting that the participants adapted to new life styles, became more mature, obtained a deeper understanding of themselves, reaffirmed their own educational values and philosophies, raised cultural awareness, became more flexible, and developed attitudes that involved tolerance and respect. Conversely, visiting faculty reported that they faced challenges related to language barriers, interaction with native speakers, classroom management, lack of support from school administrators, and separation from family.


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