scholarly journals The Agro-Industrial Sugarcane System in Mexico: Current Status, Challenges and Opportunities

2014 ◽  
Vol 6 (4) ◽  
pp. 26 ◽  
Author(s):  
Héctor Emmanuel Sentíes-Herrera ◽  
Fernando Carlos Gómez-Merino ◽  
Apolonio Valdez-Balero ◽  
Hilda Victoria Silva-Rojas ◽  
Libia Iris Trejo-Téllez
Keyword(s):  
Value Chain ◽  
Political Influence ◽  
Cane Sugar ◽  
Policy Framework ◽  
Current Status ◽  
Market Penetration ◽  
High Fructose ◽  
Wide Range ◽  
Challenges And Opportunities ◽  
High Processing

Sugarcane cultivation in Mexico occurs under a wide range of socioeconomic, environmental and agricultural conditions, with the last three harvests (2010/2011, 2011/2012 and 2012/2013) providing yields ranging from 36-125 t ha-1 (variation > 347%), with an average yield of 70.2 t ha-1, which is below the world average of 80 t ha-1. The total area allocated to sugarcane production in Mexico is close to 800 thousand hectares, and could rise to nearly 5 million hectares given adequate conditions for its cultivation. This activity generates approximately 1 million direct jobs, 2.2 million indirect jobs, and more than 2.5 billion dollars (0.4% of GDP) per year. Climate change and the rapid market penetration of high fructose corn syrup are among the greatest threats to this agribusiness, including severe disintegration of production processes in the field, industry, commerce, and consumption of cane sugar. Technology lags, low investment, high processing costs and shortcomings in production sales are issues the industry must address by leveraging their resources and coordinating processing links to be more efficient and competitive. Political influence has imposed a suboptimal policy framework to achieve the projected potential. To overcome current lags in the field and refineries within the country, significant innovations across the value-chain are underway, including a robust breeding program, digitalization of sugarcane fields and novel investments in research and development. The sugarcane value-chain has great potential for Mexico, and exploiting this potential is possible if technological, organizational and commercial management innovations currently in progress in fields and factories are applied.

scholarly journals Aligning Strategy with Sustainable Development Goals (SDGs): Process Scoping Diagram for Entrepreneurial Higher Education Institutions (HEIs)

2018 ◽  
Author(s):  
Elena Fleaca ◽  
Bogdan Fleaca ◽  
Sanda Maiduc
Keyword(s):  
Sustainable Development ◽  
Value Chain ◽  
Sustainable Development Goals ◽  
Software Tool ◽  
Research Problem ◽  
Educational Model ◽  
Society Business ◽  
Wide Range ◽  
Challenges And Opportunities ◽  
Development Goals

The sustainable development of our world has gain particular attention of a wide range of decisional factors, civil society, business sector, and scientific community, seeing that the prosperity of people and society is possible with the aid of sustained and inclusive economic growth of all countries and regions. Educational environment has a decisive impact on changes in the way that societies are coping with national, regional, and global challenges and opportunities brought by sustainable development. Looking at the implications of HE on the progress of society, the paper addressed the lack of HE institutional capacity to integrate the principles and practices of sustainable development into all aspects of education and learning. The scope of research problem was bounded on the capability of HEI as organization and school to act as entrepreneurial university by combining the scope of its responsibility within the value chain through a practical and effective mechanism needed to align the strategy with sustainable development goals (SDGs). Embarking on the path of SDGs requires HEI to design, launch, implement, and customize specific processes architectures to govern the advance of sustainability approach. The authors applied the process scoping diagram to capture and conceptualize the educational model needed to guide the HEI through the process of change to embrace sustainability into organizational culture and daily operations. It has been used the SIPOC method (Supplier, Input, Process, Output, Customer) with Visio software tool to articulate processes relationships embedded in the educational model of HEI. The benefits relied on the organized view of the work processes needed to be performed to incorporate SDGs into the strategy of any entrepreneurial HEI. Finally, the authors shared their views on the scalability of the model which may be customized and harmonized in accordance with different HE circumstances and priorities. Implementing the proposed educational model requires long-term institutional commitment, transparency, continuous performance improvement, and communicating the strategy for SDGs and its achievements to wider stakeholders.

scholarly journals Neutrophils and Macrophages as Targets for Development of Nanotherapeutics in Inflammatory Diseases

Pharmaceutics ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 1222
Author(s):  
Yujie Su ◽  
Jin Gao ◽  
Puneet Kaur ◽  
Zhenjia Wang
Keyword(s):  
Tissue Injury ◽  
Inflammatory Diseases ◽  
Current Status ◽  
Wide Range ◽  
Challenges And Opportunities ◽  
Potential Strategy ◽  
Novel Concept ◽  
Pathogen Clearance ◽  
Inflammation Responses

Neutrophils and macrophages are major components of innate systems, playing central roles in inflammation responses to infections and tissue injury. If they are out of control, inflammation responses can cause the pathogenesis of a wide range of diseases, such as inflammatory disorders and autoimmune diseases. Precisely regulating the functions of neutrophils and macrophages in vivo is a potential strategy to develop immunotherapies to treat inflammatory diseases. Advances in nanotechnology have enabled us to design nanoparticles capable of targeting neutrophils or macrophages in vivo. This review discusses the current status of how nanoparticles specifically target neutrophils or macrophages and how they manipulate leukocyte functions to inhibit their activation for inflammation resolution or to restore their defense ability for pathogen clearance. Finally, we present a novel concept of hijacking leukocytes to deliver nanotherapeutics across the blood vessel barrier. This review highlights the challenges and opportunities in developing nanotherapeutics to target leukocytes for improved treatment of inflammatory diseases.

scholarly journals Review of the Current Status of the Offshoring Industry: Insights for Practice

2018 ◽  
Vol 14 (1) ◽  
pp. 76
Author(s):  
Liyanachchi Mahesha Harshani De Silva
Keyword(s):  
Literature Review ◽  
Value Chain ◽  
Current Situation ◽  
Current Status ◽  
Future Research ◽  
Sri Lankan ◽  
Situation Analysis ◽  
Challenges And Opportunities ◽  
Current Situation Analysis ◽  
Research Frameworks

The aim of this literature review is to analyze the current situation of the offshoring industry and relate the offshoring practices into Sri Lankan context to identify the loopholes. Thereby this review identifies the challenges and opportunities for the expansion of offshoring industry in general and specific to Sri Lanka as a destination. Based on the review of 120 offshoring articles, this study extracts the insights for practice based on popular offshoring frameworks. Mainly three key major models were identified including Chile offshore services value chain, key provider evaluation criterion and A. T Kearney Global Services Location Index. These frameworks are presented with the aim of identifying a suitable study framework for future research in relation to the Sri Lankan context. This Literature review is organized into four sections such as offshoring: definitions & terms, current situation analysis, challenges of offshoring and research frameworks.

Artificial Intelligence in Advanced Manufacturing: Current Status and Future Outlook

2020 ◽  
Vol 142 (11) ◽  
Author(s):  
Jorge F. Arinez ◽  
Qing Chang ◽  
Robert X. Gao ◽  
Chengying Xu ◽  
Jianjing Zhang
Keyword(s):  
Artificial Intelligence ◽  
Manufacturing Systems ◽  
Hierarchical Organization ◽  
System Level ◽  
Current Status ◽  
Modeling And Control ◽  
Highly Nonlinear ◽  
Wide Range ◽  
Challenges And Opportunities ◽  
Collaboration Process

Abstract Today’s manufacturing systems are becoming increasingly complex, dynamic, and connected. The factory operations face challenges of highly nonlinear and stochastic activity due to the countless uncertainties and interdependencies that exist. Recent developments in artificial intelligence (AI), especially Machine Learning (ML) have shown great potential to transform the manufacturing domain through advanced analytics tools for processing the vast amounts of manufacturing data generated, known as Big Data. The focus of this paper is threefold: (1) review the state-of-the-art applications of AI to representative manufacturing problems, (2) provide a systematic view for analyzing data and process dependencies at multiple levels that AI must comprehend, and (3) identify challenges and opportunities to not only further leverage AI for manufacturing, but also influence the future development of AI to better meet the needs of manufacturing. To satisfy these objectives, the paper adopts the hierarchical organization widely practiced in manufacturing plants in examining the interdependencies from the overall system level to the more detailed granular level of incoming material process streams. In doing so, the paper considers a wide range of topics from throughput and quality, supervisory control in human–robotic collaboration, process monitoring, diagnosis, and prognosis, finally to advances in materials engineering to achieve desired material property in process modeling and control.

IMPROVEMENT OF INNOVATIVE ACTIVITY OF THE ENTERPRISE

2017 ◽  
Author(s):  
Nataliya Stoyanets ◽  
◽  
Mathias Onuh Aboyi ◽  
Keyword(s):  
Value Chain ◽  
Net Present Value ◽  
Successful Implementation ◽  
Innovative Development ◽  
Technological Equipment ◽  
Alliance Partner ◽  
Innovation Potential ◽  
Wide Range ◽  
Technological Platform ◽  
The Cost

The article defines that for the successful implementation of an innovative project and the introduction of a new product into production it is necessary to use advanced technologies and modern software, which is an integral part of successful innovation by taking into account the life cycle of innovations. It is proposed to consider the general potential of the enterprise through its main components, namely: production and technological, scientific and technical, financial and economic, personnel and actual innovation potential. Base for the introduction of technological innovations LLC "ALLIANCE- PARTNER", which provides a wide range of support and consulting services, services in the employment market, tourism, insurance, translation and more. To form a model of innovative development of the enterprise, it is advisable to establish the following key aspects: the system of value creation through the model of cooperation with partners and suppliers; creating a value chain; technological platform; infrastructure, determine the cost of supply, the cost of activities for customers and for the enterprise as a whole. The system of factors of influence on formation of model of strategic innovative development of the enterprise is offered. The expediency of the cost of the complex of technological equipment, which is 6800.0 thousand UAH, is economically calculated. Given the fact that the company plans to receive funds under the program of socio-economic development of Sumy region, the evaluation of the effectiveness of the innovation project, the purchase of technological equipment, it is determined that the payback period of the project is 3 years 10 months. In terms of net present value (NPV), the project under study is profitable. The project profitability index (PI) meets the requirements for a positive decision on project implementation> 1.0. The internal rate of return of the project (IRR) also has a positive value of 22% because it exceeds the discount rate.

Current Status and Future Perspective for Research on Medicinal Plants with Anticancerous Activity and Minimum Cytotoxic Value

2019 ◽  
Vol 20 (12) ◽  
pp. 1227-1243
Author(s):  
Hina Qamar ◽  
Sumbul Rehman ◽  
D.K. Chauhan
Keyword(s):  
Side Effects ◽  
Medicinal Plants ◽  
Anticancer Agents ◽  
Drug Targets ◽  
Psidium Guajava ◽  
Current Status ◽  
Future Perspective ◽  
Wide Range

Cancer is the second leading cause of morbidity and mortality worldwide. Although chemotherapy and radiotherapy enhance the survival rate of cancerous patients but they have several acute toxic effects. Therefore, there is a need to search for new anticancer agents having better efficacy and lesser side effects. In this regard, herbal treatment is found to be a safe method for treating and preventing cancer. Here, an attempt has been made to screen some less explored medicinal plants like Ammania baccifera, Asclepias curassavica, Azadarichta indica, Butea monosperma, Croton tiglium, Hedera nepalensis, Jatropha curcas, Momordica charantia, Moringa oleifera, Psidium guajava, etc. having potent anticancer activity with minimum cytotoxic value (IC50 >3μM) and lesser or negligible toxicity. They are rich in active phytochemicals with a wide range of drug targets. In this study, these medicinal plants were evaluated for dose-dependent cytotoxicological studies via in vitro MTT assay and in vivo tumor models along with some more plants which are reported to have IC50 value in the range of 0.019-0.528 mg/ml. The findings indicate that these plants inhibit tumor growth by their antiproliferative, pro-apoptotic, anti-metastatic and anti-angiogenic molecular targets. They are widely used because of their easy availability, affordable price and having no or sometimes minimal side effects. This review provides a baseline for the discovery of anticancer drugs from medicinal plants having minimum cytotoxic value with minimal side effects and establishment of their analogues for the welfare of mankind.

scholarly journals Current status of vascular access in Japan—from Dialysis Access Symposium 2017

2019 ◽  
Vol 20 (1_suppl) ◽  
pp. 38-44
Author(s):  
Mizuya Fukasawa
Keyword(s):  
Vascular Access ◽  
Current Status ◽  
Good Survival ◽  
Chronic Glomerulonephritis ◽  
Dialysis Access ◽  
Dialysis Patients ◽  
Survival Prognosis ◽  
Access Methods ◽  
Number Of Patients ◽  
Wide Range

At the second Dialysis Access Symposium held in Nagoya, Japan, a proposal was made to investigate the differences in vascular access methods used in different countries. In this article, we describe the management of vascular access in Japan. The Japanese population is rapidly aging, and the proportion of elderly patients on dialysis is also increasing. There were 325,000 dialysis patients in Japan at the end of 2015, of whom 65.1% were aged 65 years or above. The number of patients with diabetic nephropathy or nephrosclerosis as the underlying condition is also increasing, whereas the number with chronic glomerulonephritis is steadily decreasing. The Japanese health insurance system enables patients to undergo medical treatment at almost no out-of-pocket cost. Percutaneous transluminal angioplasty suffers from a severe device lag compared with other countries, but although there are limitations on permitted devices, the use of those that have been authorized is covered by medical insurance. One important point that is unique to Japan is that vascular access is performed and managed by doctors involved in dialysis across a wide range of disciplines, including nephrologists, surgeons, and urologists. This may be one factor contributing to the good survival prognosis of Japanese dialysis patients.

Wide-Range Many-Core SoC Design in Scaled CMOS: Challenges and Opportunities

2021 ◽  
Vol 29 (5) ◽  
pp. 843-856
Author(s):  
Sriram Vangal ◽  
Somnath Paul ◽  
Steven Hsu ◽  
Amit Agarwal ◽  
Saurabh Kumar ◽  
...  
Keyword(s):  
Wide Range ◽  
Challenges And Opportunities ◽  
Many Core ◽  
Scaled Cmos

scholarly journals MOCVD Grown HgCdTe Heterostructures for Medium Wave Infrared Detectors

Coatings ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 611
Author(s):  
Waldemar Gawron ◽  
Jan Sobieski ◽  
Tetiana Manyk ◽  
Małgorzata Kopytko ◽  
Paweł Madejczyk ◽  
...  
Keyword(s):  
Buffer Layer ◽  
Infrared Detectors ◽  
Lattice Mismatch ◽  
Layer Growth ◽  
Ex Situ ◽  
Current Status ◽  
Organic Chemical ◽  
Infrared Band ◽  
Donor And Acceptor ◽  
Wide Range

This paper presents the current status of medium-wave infrared (MWIR) detectors at the Military University of Technology’s Institute of Applied Physics and VIGO System S.A. The metal–organic chemical vapor deposition (MOCVD) technique is a very convenient tool for the deposition of HgCdTe epilayers, with a wide range of compositions, used for uncooled infrared detectors. Good compositional and thickness uniformity was achieved on epilayers grown on 2-in-diameter, low-cost (100) GaAs wafers. Most growth was performed on substrates, which were misoriented from (100) by between 2° and 4° in order to minimize growth defects. The large lattice mismatch between GaAs and HgCdTe required the usage of a CdTe buffer layer. The CdTe (111) B buffer layer growth was enforced by suitable nucleation procedure, based on (100) GaAs substrate annealing in a Te-rich atmosphere prior to the buffer deposition. Secondary-ion mass spectrometry (SIMS) showed that ethyl iodide (EI) and tris(dimethylamino)arsenic (TDMAAs) were stable donor and acceptor dopants, respectively. Fully doped (111) HgCdTe heterostructures were grown in order to investigate the devices’ performance in the 3–5 µm infrared band. The uniqueness of the presented technology manifests in a lack of the necessity of time-consuming and troublesome ex situ annealing.

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