The influence of the body mass index (BMI) on selected parameters of the coagulation system in patients with disorders of the balance system taking oral contraceptives

2016 ◽  
Vol 70 (4) ◽  
pp. 28-34 ◽  
Author(s):  
Marzena Bielińska ◽  
Joanna Urbaniak ◽  
Krzysztof Kuśmierczyk ◽  
Jurek Olszewski ◽  
Piotr Pietkiewicz

Introduction: The objective of the paper is to evaluate the influence of the body mass index (BMI) on selected parameters of the coagulation system in patients with disorders of the balance system taking oral contraceptives. Material and methods: 105 young women participated in the study who were divided into 2 groups. Group I: 52 women disorders of the balance system taking hormonal contraceptives for at least 2 months, between the age of 20–49; Group II: 53 women with no disorders of the balance system taking hormonal contraceptives for at least 2 months, between the age of 18–40. Patients entering the study underwent full otoneurological examination, detailed laryngological assessment and the examination of selected parameters of the hemostasis system, including the evaluation of fibrinogen and D-dimer levels, APTT and PT, estradiol and progesterone concentrations in the blood serum and evaluation of the body mass index (BMI). Results: Central vertigo was the most common type of vertigo in the study group (59,6% of cases). Other vertigo types in this group included compensated vertigo of mixed origin (36,6% of cases) and peripheral vertigo (only 3,8% of cases), which indicates that 40.4% of the cases suffer from damage to the labyrinth. The analysis of the concentration of estradiol in the blood serum revealed, after consideration of a menstrual cycle phase, that estradiol concentration exceeded normative values significantly more often in the study group than in the control group and that estradiol concentration was significantly less frequently below the norm in the study group; the difference was statistically significant (p=0,048). The body mass index (BMI) of women participating in the study significantly correlated with the concentration of D-dimers only in the study group (p=0,35 vs p=0,012). Conclusions: Evaluating the body mass index before administering hormonal contraception can be useful to eliminate other risk factors for thromboembolism. In order to prevent potential thromboembolism episodes, administering hormonal contraception only after lowering the body mass index may also be worth considering.

2021 ◽  
Vol 57 (2) ◽  
pp. 104
Author(s):  
Alisiya Alisiya ◽  
Sulistiawati Sulistiawati ◽  
Patricia Maria Kurniawati ◽  
RR Indrayuni Lukitra Wardhani

Osteoarthritis (OA) is a degenerative disease related to joint cartilage and commonly occurs in the knee joint. The 2013 National Survey recorded the prevalence of joint diseases in East Java was 26.9%. OA affected more women than men due to the estrogen and caused disabilities in many women. This study aimed to find the relationship between Body Mass Index (BMI), age of menarche, parity, and the use of hormonal contraceptives against OA in genu at Universitas Airlangga Hospital, Surabaya. This was an analytic observational study with a case-control approach. Data collection was carried out through a short interview using a questionnaire. The sample size was calculated using a formula and found that the study required 42 patients with OA in the case group and 42 patients without OA in the control group. The case group was dominated by patients with 56-60 years old age (62.1%), BMI 23-24.9 kg/m2 (58.7%), menarche age 12-13 years (53.6%), multiparous (52.6%), having contraception pill usage history (62.3%) particularly using combination pills (60.5%) with a mean duration of use > 1 year (56.8%). There was a relationship between BMI and type of hormonal contraceptive used against genu OA in female patients at Universitas Airlangga Hospital Surabaya.


2012 ◽  
Vol 18 (2) ◽  
pp. 72-76
Author(s):  
Irina Tica ◽  
V.I. Tica ◽  
Claudia Mihailov ◽  
A. Mitroi

AbstractIntroduction and aim: Because for the majority of women one of the most unwanted effect of combined oral contraceptive use is considered to be weight increasement, our study aim was to find out if there is a correlation between the use of combined oral contraceptives in the present or past and the body mass index in a group of pregnant, puerperal and matching control patients.Material, patients and method:In a prospective cohort (Regional University Hospital - Constanţa), 176 patients were included in 3 groups: pregnant, puerperal and matching non-pregnant women (control). For each patient a chart was considered, with the following parameters, age, height, weight, BMI, type of diet, use of combined oral contraceptives in the present or in the past (more than 6 months), ultrasound evaluation of gallbladder’ content.Conclusion:In our study, the use of combined oral contraceptives was not correlated with a high BMI but it seems to correlate with a higher incidence of biliary dyspeptic symptoms in patients without biliary sludge or stones.


2017 ◽  
Vol 2 (1) ◽  
Author(s):  
Rohmi Handayani ◽  
Siti Yulaikah

Abstract: Blood Pressure, BMI, and Injectable DMPA Injectable Combination. Hormonal contraception is a type of contraception most widely used by women,especially in developed countries because of this effectiveness in preventing pregnancy. Hormonal contraceptives are currently available can be pills, injections or implants. Although effective in preventing pregnancy on the other hand can cause various side effects include is weight gain and increased blood pressure in the acceptor.The purpose of this reasearch is to determine differences in blood pressure rise acceptor combination hormonal injections and blood pressure acceptor DMPA injections and to determine differences in body mass index increase acceptors injectable hormonal combination with a body mass index in injectable DMPA acceptors.Type of this reasearch is an analytic survey with cross sectional study design. The population in this study are all injectable acceptor in the Klaten area totaling 95 512 acceptors. The sample size is 500 samples taken which comprises a group acceptor and acceptor combined injectable DMPA injections. The sampling technique used in this research is purposive sampling. Analysis of data using non-parametric test with Mann Whitney test.There was no significant difference between the increase in systolic blood pressure acceptor and acceptor combined injectable DMPA injections, P = 0.338. There was no significant difference between the increase in diastolic blood pressure acceptor and acceptor combined injectable DMPA injections, P = 0,917.there was significant difference between the increase in BMI acceptor and acceptor combined injectable DMPA injections, P = 0.000.There was no significant difference between the increase in blood pressure and acceptor acceptor combined injectable DMPA injections. There is a significant difference between the increase in BMI acceptor and acceptor combined injectable DMPA injections.


2007 ◽  
Vol 177 (4S) ◽  
pp. 64-64
Author(s):  
Murugesan Manoharan ◽  
Martha A. Reyes ◽  
Alan M. Nieder ◽  
Bruce R. Kava ◽  
MarkS Soloway

Author(s):  
K. Subramanyam ◽  
Dr. P. Subhash Babu

Obesity has become one of the major health issues in India. WHO defines obesity as “A condition with excessive fat accumulation in the body to the extent that the health and wellbeing are adversely affected”. Obesity results from a complex interaction of genetic, behavioral, environmental and socioeconomic factors causing an imbalance in energy production and expenditure. Peak expiratory flow rate is the maximum rate of airflow that can be generated during forced expiratory manoeuvre starting from total lung capacity. The simplicity of the method is its main advantage. It is measured by using a standard Wright Peak Flow Meter or mini Wright Meter. The aim of the study is to see the effect of body mass index on Peak Expiratory Flow Rate values in young adults. The place of a study was done tertiary health care centre, in India for the period of 6 months. Study was performed on 80 subjects age group 20 -30 years, categorised as normal weight BMI =18.5 -24.99 kg/m2 and overweight BMI =25-29.99 kg/m2. There were 40 normal weight BMI (Group A) and 40 over weight BMI (Group B). BMI affects PEFR. Increase in BMI decreases PEFR. Early identification of risk individuals prior to the onset of disease is imperative in our developing country. Keywords: BMI, PEFR.


2020 ◽  
Author(s):  
Valentina Cazzato ◽  
Elizabeth Walters ◽  
Cosimo Urgesi

We examined whether visual processing mechanisms of the body of conspecifics are different in women and men and whether these rely on westernised socio-cultural ideals and body image concerns. Twenty-four women and 24 men performed a visual discrimination task of upright or inverted images of female or male bodies and faces (Experiment 1) and objects (Experiment 2). In Experiment 1, both groups of women and men showed comparable abilities in the discrimination of upright and inverted bodies and faces. However, the genders of the human stimuli yielded different effects on participants’ performance, so that male bodies and female faces appeared to be processed less configurally than female bodies and male faces, respectively. Interestingly, altered configural processing for male bodies was significantly predicted by participants’ Body Mass Index (BMI) and their level of internalization of muscularity. Our findings suggest that configural visual processing of bodies and faces in women and men may be linked to a selective attention to detail needed for discriminating salient physical (perhaps sexual) cues of conspecifics. Importantly, BMI and muscularity internalization of beauty ideals may also play a crucial role in this mechanism.


2020 ◽  
Vol 66 (1) ◽  
pp. 71-78
Author(s):  
Lev Bershteyn ◽  
Aleksandr Ivantsov ◽  
Aglaya Ievleva ◽  
A. Venina ◽  
I. Berlev

The aim of this study was to evaluate steroid receptors’ status of tumor tissue in different molecular biological types of endometrial cancer (EC), subdivided according to the current classification, and their colonization by lymphocytic and macrophage cells, taking into account body mass index of the patients. Materials and methods: Material from treatment-naive patients with EC (total n = 229) was included; the number of sick persons varied depending on the method used. The average age of patients was close to 60 years, and about 90% of them were postmenopausal. It was possible to divide the results of the work into two main subgroups: a) depending on the molecular biological type of the tumor (determined on the basis of genetic and immunohistochemical analysis), and b) depending on the value of the body mass index (BMI). The latter approach was used in patients with EC type demonstrating a defective mismatch repair of the incorrectly paired nucleotides (MMR-D) and with a type without characteristic molecular profile signs (WCMP), but was not applied (due to the smaller number of patients) in EC types with a POLE gene mutation or with expression of the oncoprotein p53. According to the data obtained, when comparing various types of EC, the lowest values of Allred ER and PR scores were revealed for POLE-mutant and p53 types, while the “triple-negative” variant of the tumor (ER-, PR-, HER2/neu-) was most common in POLE-mutant (45.5% of cases) and WCMP (19.4%) types of EC. The p53+ type of EC is characterized by inclination to the higher expression of the macrophage marker CD68 and lymphocytic Foxp3, as well as mRNA of PD-1 and SALL4. In addition to the said above, for WCMP type of EC is peculiar, on the contrary, a decrease in the expression of lymphocytic markers CD8 (protein) and PD-L1 (mRNA). When assessing the role of BMI, its value of >30.0 (characteristic for obesity) was combined with an inclination to the increase of HER-2/neu expression in the case of MMR-D EC type and to the decrease of HER-2 /neu, FOXp3 and ER expression in WCMP type. Conclusions: The accumulated information (mainly describing here hormonal sensitivity of the tumor tissue and its lymphocytic-macrophage infiltration) additionally confirms our earlier expressed opinion that the differences between women with EC are determined by both the affiliation of the neoplasm to one or another molecular biological type (subdivided according to the contemporary classification), as well as by body mass value and (very likely) the associated hormonal and metabolic attributes.


2005 ◽  
Vol 81 (4) ◽  
pp. 305-309 ◽  
Author(s):  
Vitor E. Cassol ◽  
Tiago M. Rizzato ◽  
Stefania P. Teche ◽  
Débora F. Basso ◽  
Vânia N. Hirakata ◽  
...  
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