scholarly journals Effects of Astragalus membranaceus roots supplementation on growth performance, serum antioxidant and immune response in finishing lambs

2020 ◽  
Vol 33 (6) ◽  
pp. 965-972 ◽  
Author(s):  
Xiaoyan Hao ◽  
Pengju Wang ◽  
Youshe Ren ◽  
Gentang Liu ◽  
Jianxin Zhang ◽  
...  
Keyword(s):  
Immune Response ◽  
Growth Performance ◽  
Optimal Dose ◽  
Astragalus Membranaceus ◽  
Feed Additive ◽  
Immune Functions ◽  
Traditional Chinese Herbal Medicine ◽  
Total Antioxidant ◽  
Quadratic Response ◽  
Total Superoxide Dismutase

Objective: <i>Astragalus membranaceus</i> root is a well-known traditional Chinese herbal medicine with many biological active constituents. This study was conducted to examine the effects of <i>Astragalus membranaceus</i> root powder (AMP) on growth performance, serum antioxidant and immune response in finishing lambs.Methods: A total of thirty-six Guangling fat-tailed ram lambs (body weight = 19±2 kg, mean ±standard deviation) were randomly assigned to one of six treatments for a 40 d feeding period, with the first 10 d for adaptation. Treatments consisted of the lambs’ basal diets with addition of 0, 5, 10, 15, 20, and 30 g/kg of diet of AMP.Results: Response to supplementation level of AMP was quadratic (p≤0.032) for final weight and ADG with the greatest at 10 g/kg of diet, but dry matter intake was not affected (p≥0.227) by treatments. The increase of AMP supplementation resulted in a quadratic response in contents of triglyceride and creatinine (p<0.05), with the lowest values for 10 and 20 g/kg of diet, respectively. A linear and quadratic decrease was observed in activity of alkaline phosphatase in serum of lambs. As the AMP supplementation increased, the activities of total superoxide dismutase and total antioxidant capacity increased linearly (p≤0.018) and hydroxyl radical (OH<sup>–</sup>) decreased linearly (p = 0.002). For catalase (CAT) and malondialdehyde (MDA), quadratic (p≤0.001) effects were observed among treatments, with the greatest CAT and lowest MDA values at 10 g/kg AMP. Additionally, supplementing AMP up to a level of 10 or 15 g/kg of diet quadratically increased immunoglobulin and interleukin contents in the serum.Conclusion: The results indicated that AMP can be used as natural feed additive in the ration of lambs to improve ADG, antioxidant status, and immune functions, and the optimal dose was 10 g/kg of diet under the condition of this experiment.

Effects of Moringa Oleifera Leaf Polysaccharide on Growth Performance and Immune Response of Broiler Chickens

2021 ◽  
Author(s):  
Hosameldeen Mohamed Husien ◽  
JunJie Huang ◽  
WeiLong Peng ◽  
ShuMei Zheng ◽  
JinGui Li
Keyword(s):  
Immune Response ◽  
Growth Performance ◽  
Broiler Chickens ◽  
Moringa Oleifera ◽  
The Body ◽  
Feed Consumption ◽  
Feed Additive ◽  
Control Group ◽  
High Dose ◽  
Tnf Α

Abstract Moringa oleifera (MO) is a widely used as the nutritious and non-traditional feed supplementation containing kinds of bioactive substances. However, the enhancement effect of Moringa oleifera leaf Polysaccharide (MOLP) as a feed additive in broilers growth performance and immunity remains unclear. In this study, MOLP was obtained by water extraction and alcohol precipitation method, then purified with Trichloroacetic acid (TCA) assay. Chickens were randomly divided into 4 groups, to receive different doses of MOLP (0, 0.1, 0.2, 0.4g/kg) in feed for 3 weeks. The body weight gain (BWG) and feed consumption were recorded for feed conversion ratio (FCR) and average daily feed intake (ADFI) calculation. Broiler chickens were sacrificed and sampled on day 14, 21, 28 (D 14, D 21, and D 28) respectively. Serological indicators, including total protein (TP), albumin (ALB), globulin (GLO), and creatinine (CREA) were detected. ELISA kits were applied for detecting the levels of immunoglobulin A (IgA), immunoglobulin G (IgG), interleukin-2 (IL-2), and tumor necrosis factor (TNF-α). From D 21 to D 28, the results showed that middle dose of MOLP significantly increased BWG and ADFI as well as liver and bursa indexes when compared with the control group. In addition, TP and GLO were also increased (P<0.05). All MOLP treatments enhanced the serum concentrations of IgG and IL-2 (P<0.01). Furthermore, results of quantitative RT-PCR showed that high dose of MOLP treatment significantly increased (P<0.001) the mRNA expression levels of IL-2 and TNF-α of chickens relative to the control group. In conclusion, the results showed that MOLP supplementation contributed to improve growth performance and immune response in broiler chickens, and MOLP could be considered as a promising feed additive.

scholarly journals Polygonatum sibiricum polysaccharide affects growth performance and immune response in cyclophosphamide-induced immunosuppressed chickens

2019 ◽  
Author(s):  
Dan Xu ◽  
Jin Zhao ◽  
Chonglin Ran ◽  
Lu Xu ◽  
Shaojun Ren ◽  
...  
Keyword(s):  
Immune Response ◽  
Growth Performance ◽  
Relative Weight ◽  
Blood Parameters ◽  
Immunoglobulin M ◽  
Antioxidant Ability ◽  
Feed Conversion ◽  
Immunological Stress ◽  
Total Antioxidant ◽  
Antibody Titers

Abstract Background: This study aims to identify the effects of dietary Polygonatum sibiricum polysaccharide (PP) on growth performance and blood parameters in immunosuppressed chickens induced by cyclophosphamide (CY). Results: The results showed that PP enhanced the growth performance and immune response in chickens treated with cyclophosphamide characterized by increasing relative weight of thymus, total antioxidant capacity (T-AOC), superoxidase dismutase (SOD), albumin (ALB), immunoglobulin M (IgM), and antibody titers of Newcastle disease (ND) and avian influenza (H9), and decreasing feed conversion ratio (FCR) and malondialdehyde (MDA) level. Conclusions: PP enhanced chickens’ growth performance via improving antioxidant ability and alleviating CY-induced immunological stress.

The use of bromelain as a feed additive in fish diets: Growth performance, intestinal morphology, digestive enzyme and immune response of juvenile Sterlet (Acipenser ruthenus)

2019 ◽  
Vol 25 (6) ◽  
pp. 1289-1299 ◽  
Author(s):  
Grzegorz Wiszniewski ◽  
Sylwia Jarmołowicz ◽  
Mohamed S. Hassaan ◽  
Eman Y. Mohammady ◽  
Mohamed R. Soaudy ◽  
...  
Keyword(s):  
Immune Response ◽  
Growth Performance ◽  
Digestive Enzyme ◽  
Intestinal Morphology ◽  
Feed Additive ◽  
Acipenser Ruthenus ◽  
Fish Diets ◽  
Sterlet Acipenser Ruthenus

scholarly journals Effect of Dietary Sugarcane Bagasse Supplementation on Growth Performance, Immune Response, and Immune and Antioxidant-Related Gene Expressions of Nile Tilapia (Oreochromis niloticus) Cultured under Biofloc System

Animals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 2035
Author(s):  
Chompunut Lumsangkul ◽  
Wanaporn Tapingkae ◽  
Korawan Sringarm ◽  
Sanchai Jaturasitha ◽  
Chinh Le Xuan ◽  
...  
Keyword(s):  
Immune Response ◽  
Growth Performance ◽  
Sugarcane Bagasse ◽  
Nile Tilapia ◽  
Basal Diet ◽  
Feed Additive ◽  
Related Gene ◽  
Gene Expressions ◽  
Antioxidant Genes ◽  
Nile Tilapia Oreochromis Niloticus

We investigated, herein, the effects of dietary inclusion of sugarcane bagasse powder (SB) on Nile tilapia development, mucosal and serum immunities, and relative immune and antioxidant genes. Fish (15.12 ± 0.04 g) were provided a basal diet (SB0) or basal diet incorporated with SB at 10 (SB10), 20 (SB20), 40 (SB40), or 80 (SB80) g kg−1 for 8 weeks. Our results demonstrated that the dietary incorporation of sugarcane bagasse powder (SB) at 20 and 40 g kg−1 significantly ameliorated FW, WG, and SGR as opposed to fish fed basal, SB10, and SB80 diets. However, no significant changes in FCR and survivability were observed between the SB supplemented diets and the control (basal diet). The mucosal immunity exhibited significantly higher SMLA and SMPA activities (p < 0.005) in fish treated with SB diets after eight weeks. The highest SMLA and SMPA levels were recorded in fish fed SB80 followed by SB20, SB40, and SB10, respectively. For serum immunity, fish fed SB incorporated diets significantly ameliorated SL and RB levels (p < 0.05) compared with the control. However, SP was not affected by the inclusion of SB in any diet throughout the experiment. The expression of IL1, IL8, LBP, GSTa, GPX, and GSR genes in the fish liver was significantly increased in fish fed the SB20 and SB10 diets relative to the basal diet fed fish (p < 0.05); whereas only the IL8, LBP, and GPX genes in the intestines were substantially augmented via the SB20 and SB80 diets (p < 0.05). IL1 and GSR were not influenced by the SB incorporated diets (p > 0.05). In summary, sugarcane bagasse powder (SB) may be applied as a feed additive to improve growth performance, immune response, and immune and antioxidant-related gene expression in Nile tilapia.

PSIII-22 Impact of a Dietary Phytogenic Feed Additive on Growth Performance of Growing Finishing Pigs

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 173-174
Author(s):  
Aileen Joy Mercado ◽  
Terry Weeden ◽  
Huyen Tran ◽  
Emily Otto-Tice ◽  
Murali Raghavendra Rao ◽  
...  
Keyword(s):  
Growth Performance ◽  
Positive Impact ◽  
Average Daily Gain ◽  
Linear Increase ◽  
Feed Additive ◽  
Finishing Pigs ◽  
Orthogonal Contrasts ◽  
Feeding Program ◽  
Quadratic Response ◽  
Dietary Treatments

Abstract Abstract: Two experiments were conducted involving a total of 1560 pigs (25.82 kgs, PIC and Hypor) to evaluate if phytogenic feed additive (PFA), containing essential oils and pungent substances, has positive impact on growth performance of growing finishing pigs. Pens in each experiment (Study 1: 11 pens, 20 pigs per pen; Study 2: 15 pens, 20 pigs per pen) were randomly allocated to one of 3 dietary treatments containing 0, 68, or 136 g/ton of the PFA. Feeding program consisted of 3 feeding phases of 21 d each. Body weight (BW), average daily gain (ADG), average daily feed intake (ADFI) and gain to feed (GF) were measured for each phase and overall. Performance data were analyzed using PROC MIX of SAS using RCBD design with dietary inclusion of PFA, pen location blocked within a study and initial BW as covariate. Orthogonal contrasts were used to determine linear or quadratic effect of PFA. No significant differences (P&gt;0.20) were observed in ADG, ADFI or GF during the first 2 phases of the study. During phase 3 however, increasing the level of PFA resulted in a linear increase in ADG (P&lt; 0.001) and a quadratic response in ADFI (P&lt; 0.05) and GF (P&lt; 0.05). Overall, linear improvements in ADG (P&lt; 0.001) was observed with addition of PFA in the diets (+2.5%, +3% vs. NC). Similarly, increasing the level of PFA in the diet tended to linearly improve final BW (P&lt; 0.10, +0.9%, +1.6% vs. NC). The results of this study indicate a positive impact of feeding a PFA on growth of growing-finishing pigs.

scholarly journals The effect of deoxynivalenol-contaminated corn and an immune-modulating feed additive on growth performance and immune response of nursery pigs fed corn- and soybean meal-based diets

2021 ◽  
Vol 5 (4) ◽  
Author(s):  
Élise Lafleur Larivière ◽  
Cuilan Zhu ◽  
Sabrina Zettell ◽  
Robert Patterson ◽  
Niel A Karrow ◽  
...  
Keyword(s):  
Immune Response ◽  
Growth Performance ◽  
Soybean Meal ◽  
Low Complexity ◽  
Feed Additive ◽  
Contamination Level ◽  
Nursery Pigs ◽  
Humoral Immune ◽  
Feeding Program ◽  
Specific Igg

Abstract One hundred eighty newly weaned pigs (21 days of age; 6.9 ± 0.2 kg BW) were used to determine the effects of deoxynivalenol- (DON) contaminated corn and an immune-modulating feed additive on growth performance and immune response of nursery pigs fed corn- and soybean meal-based diets. Pens were randomly assigned to one of five diets: a high-complexity (HC; containing animal protein sources) or one of four low-complexity diets (LC; containing soybean meal as the main protein source) arranged in a 2 × 2 factorial with low (lDON; average 1.4 ppm) or high (hDON; average 3.5 ppm) DON and with or without a feed additive (2 g/kg in complete feed; n = 6 pens per treatment) provided in a three-phase feeding program. On day 7, small intestinal histomorphology was assessed in two pigs per pen. On days 8 and 25, two pigs per pen were immunized with ovalbumin (OVA). Blood was collected on days 8, 25, and 38 for determination of OVA-specific IgG. There were no corn type by feed additive interactions or feed additive effects for growth performance. The ADG, ADFI, and G:F in phase I were not different for pigs fed hDON vs. lDON, but were less than those fed the HC diet (contrasts; P &lt; 0.05). Over the entire nursery period, ADG and ADFI were less for pigs fed hDON vs. those fed lDON (407 vs. 484 g and 651 vs. 769 g, respectively; P &lt; 0.05), ADG was less for pigs fed hDON vs. HC (496 g; P &lt; 0.05), and pigs fed lDON had ADG and ADFI not different from those fed the HC diet. Pigs fed hDON had lower final BW than those fed lDON (24.6 vs. 27.6 kg; P &lt; 0.01) and tended to have lower final BW than pigs fed the HC diet (27.3 kg; contrast; P = 0.052); final BW was not different between pigs fed lDON and HC diets. Jejunal villus heights were shorter for pigs fed hDON and lDON compared to pigs fed HC (438 and 466 vs. 538 µm; contrasts; P &lt; 0.05 and P = 0.090, respectively) and the villus:crypt ratio tended to be less for pigs fed hDON vs. those fed HC (1.87 vs. 2.22; contrast; P = 0.091). On day 38, plasma OVA-specific IgG 1 tended to be less for pigs fed hDON compared to HC (contrast; P = 0.075) and OVA-specific total IgG were less for pigs fed LC diets without the feed additive vs. HC (P &lt; 0.05). Therefore, high DON (~3.5 ppm) in LC nursery diets interfered with compensatory growth and the humoral immune response. The feed additive did not rescue growth performance, regardless of DON contamination level in LC nursery diets.

scholarly journals A Review on Effects of Aloe Vera as a Feed Additive in Broiler Chicken Diets

2014 ◽  
Vol 14 (3) ◽  
pp. 491-500 ◽  
Author(s):  
Darabighane Babak ◽  
Samuel N. Nahashon
Keyword(s):  
Immune Response ◽  
Growth Performance ◽  
Broiler Chickens ◽  
Broiler Chicken ◽  
Aloe Vera ◽  
Ethanolic Extract ◽  
Feed Additive ◽  
Growth Promoters ◽  
Antibiotic Growth Promoters ◽  
Anti Fungal

AbstractProhibition of application of antibiotic growth promoters in broiler chicken diets has resulted in increased use of herbs as natural additives in broiler feeds over the recent years. Researchers particularly look for herbs that can affect such parameters as growth performance, immune response, or treatment of certain diseases. Aloe vera is a well-known herb characterized by properties such as anti-bacterial, anti-viral, anti-fungal, anti-tumor, anti-inflammatory, immunomodulatory, wound-healing, anti-oxidant, and anti-diabetic effects. During the past years, attention has shifted toward Aloe vera as a natural additive to broiler diets, and studies have shown that Aloe vera can improve immune response and growth performance in broilers. In addition, Aloe vera is an excellent alternative for antibiotic growth promoters and anticoccidial drugs. Since Aloe vera can be used for broilers in the form of gel, powder, ethanolic extract, aqueous extract, and a polysaccharide contained in Aloe vera gel (i.e. acemannan), more studies are required to determine the best form and to compare Aloe vera with other medicinal herbs. This paper reviews effects of Aloe vera on intestinal microflora, growth performance, immune response, and coccidiosis in broiler chickens.

Dietary inclusion level effects of a phytogenic characterised by menthol and anethole on broiler growth performance, biochemical parameters including total antioxidant capacity and gene expression of immune-related biomarkers

2017 ◽  
Vol 57 (1) ◽  
pp. 33 ◽  
Author(s):  
Vasileios Paraskeuas ◽  
Konstantinos Fegeros ◽  
Christine Hunger ◽  
Georgios Theodorou ◽  
Konstantinos C. Mountzouris
Keyword(s):  
Gene Expression ◽  
Antioxidant Capacity ◽  
Growth Performance ◽  
Total Antioxidant Capacity ◽  
Biochemical Parameters ◽  
Nutrient Digestibility ◽  
Feed Additive ◽  
Feed Conversion ◽  
Inflammatory Biomarker ◽  
Total Antioxidant

The supplementation of a phytogenic feed additive (PFA) characterised by menthol and anethole was evaluated at three levels on broiler growth performance, nutrient digestibility, biochemical parameters, total antioxidant capacity of plasma, breast and thigh meat as well as on the relative gene expression of immune-related biomarkers. A total of 225 1-day-old male Cobb-500 were assigned into three treatments with five replicates of 15 chicks each. Wheat-soybean meal basal diets were formulated according to a three-phase (i.e. starter, grower and finisher) feeding program. Dietary treatments were: no PFA, PFA at 100 mg/kg diet and PFA at 150 mg/kg diet. Feed and water were available ad libitum. Performance parameters were monitored weekly and all other biological responses were determined at 42 days of broiler age. Increasing PFA level increased (P = 0.044) bodyweight gain at finisher period, decreased quadratically (P = 0.035) overall feed intake, and quadratically improved (P = 0.024) overall feed conversion ratio. Moreover, increasing PFA level increased plasma total antioxidant capacity linearly (P = 0.001) whereas linearly decreased (P = 0.005) triglyceride concentration. Thigh meat cholesterol decreased linearly (P = 0.016) with increasing PFA level. Expression of pro-inflammatory cytokine IL-2 in caecal tonsils increased quadratically (P = 0.046) with increasing PFA level. In conclusion, PFA inclusion at 100 mg/kg diet affected positively performance whereas a stronger improvement mainly in plasma total antioxidant capacity and triglyceride as well as in meat cholesterol was noted for the 150 mg/kg diet level. Inclusion of PFA resulted in increasing pro-inflammatory biomarker IL-2 at local caecal level.

scholarly journals Role of Aloe Vera as A Natural Feed Additive in Broiler Production

2019 ◽  
Vol 7 (sp1) ◽  
pp. 163
Author(s):  
Hassan Jalal ◽  
Muhammad Zeeshan Akram ◽  
Sibel Canoğulları Doğan ◽  
Sema Yaman Fırıncıoğlu ◽  
Nida Irshad ◽  
...  
Keyword(s):  
Immune Response ◽  
Growth Performance ◽  
Broiler Chickens ◽  
Aloe Vera ◽  
Ethanolic Extract ◽  
Feed Additives ◽  
Feed Additive ◽  
Growth Promoters ◽  
Broiler Production ◽  
Broiler Diet

Phytogenic feed additives have replaced the use of antibiotic growth promoters (AGP) in the diet of poultry particularly broiler chickens. Researchers are moving towards the use of natural products such as herbs, spices, plants and plant products, which possess influential effects on growth performance parameters, immune response and treatment of various diseases. Aloe vera is a well-known medicinal plant and is being used for commercial and therapeutic purposes such as antimicrobials, antitumor, anti-inflammatory, immunomodulator, wound healing, antioxidant and antiprotozoal agents. From a few last decades, the use of Aloe vera has been increased as a natural additive to broiler diet. Based on the review of literature, Aloe vera can improve immune response, growth performance in the broiler, as well as an excellent alternative of AGPs and anticoccidial drugs. It can be used for broiler diet in the form of gel, powder, ethanolic extract and aqueous extract. This review provides information about the use of Aloe vera in broiler production with reference to the effects on growth performance, immune system, intestinal microflora and coccidiosis in broiler chickens.

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