Horst Wolfram Geißler (1893–1983)

2021 ◽  
Author(s):  
Frank Schulz-Nieswandt
Keyword(s):  
Life Cycle ◽  
Critical Theory ◽  
Central Question ◽  
Key Points

This study analyses the work of Horst Wolfram Geißler and his poetics in the context of the post-1945 period. Its hermeneutical reconstruction focuses on questions relating to ontological reflections on freedom and destiny with regard to developmental challenges during the life cycle of individuals. Its central question relates to understanding the role of cheerfulness and merriment in confrontation with existential tasks of meaningfulness. The study’s autobiographical dimensions facilitate certain relevant intertextual mechanisms of hermeneutics. Understanding the compensatory role of the poetics of cheerfulness and merriment in relation to the melancholy and negativity of social reality’s critical theory is also one of its key points.

scholarly journals Summarizing comments on the discussion and a prospectus for urgent future action

2016 ◽  
Vol 374 (2061) ◽  
pp. 20150226 ◽  
Author(s):  
John Meurig Thomas
Keyword(s):  
Carbon Dioxide ◽  
Life Cycle ◽  
Single Site ◽  
Future Action ◽  
Key Points ◽  
Anthropogenic Carbon ◽  
Earth Abundant ◽  
Economic Analyses ◽  
Made In

Following my personal reactions to some of the key points made in this Discussion (Part I), I present, in Part II, what I perceive to be the most important, and, in some cases, urgent actions that now need to be taken in the following inter-related fields: (i) design of catalysts, especially for the production of materials using anthropogenic carbon dioxide, CO 2 , as feedstock; (ii) the continuing role of catalysis in the protection of the environment; (iii) the importance of catalysis in the generation of fuel and the release of energy; and (iv) the wisdom of conducting life cycle and techno-economic analyses continually during the development of new catalysts, as well as of those in regular use. A brief account is also given of the prospect of designing atom-efficient catalysts in which either atomically dispersed rare (and expensive) metals such as Ir or Pt or the use of single-site earth-abundant elements (Al, Si, O) can be employed to facilitate important industrial reactions.

ASPECTS IN BUILDING A COMPANY WEB-SITE AND ITS ROLE FOR THE DEVELOPMENT OF BUSINESS

2018 ◽  
pp. 117-124
Author(s):  
Petar Halachev ◽  
Victoria Radeva ◽  
Albena Nikiforova ◽  
Miglena Veneva
Keyword(s):  
Life Cycle ◽  
Web Site ◽  
The Internet ◽  
A Company ◽  
The Web ◽  
Design Construction ◽  
Made In ◽  
Site Types

This report is dedicated to the role of the web site as an important tool for presenting business on the Internet. Classification of site types has been made in terms of their application in the business and the types of structures in their construction. The Models of the Life Cycle for designing business websites are analyzed and are outlined their strengths and weaknesses. The stages in the design, construction, commissioning, and maintenance of a business website are distinguished and the activities and requirements of each stage are specified.

The Fight to Save Welfare for Low-Income Older Asian Immigrants: The Role of National Asian American Organizations

2003 ◽  
Vol 1 (1) ◽  
pp. 85-101 ◽  
Author(s):  
Grace Yoo
Keyword(s):  
Welfare Reform ◽  
Asian American ◽  
Low Income ◽  
Bill Clinton ◽  
Asian Immigrants ◽  
Central Question ◽  
Political Debate ◽  
Welfare Reform Law ◽  
Selection Of

The welfare reform law of August 1996 signed by President Bill Clinton put an end to immigrants’ eligibility of federal means tested entitlements. The rollbacks on welfare are the most drastic for older, low-income Asian immigrants who are on Supplemental Security Income. The article’s focus is in on national Asian American organizations who are involved in this political debate. The central question discuss is how did national Asian American organizations characterize and affect the 1996 federal welfare reform and immigrant debate. The selection of organizations that was studied and the findings of that investigation, along with the assessment of its effectiveness and the resources barriers they face are discussed.

Introduction

2018 ◽  
Author(s):  
Christopher Evan Franklin
Keyword(s):  
Moral Responsibility ◽  
Free Will ◽  
Human Agency ◽  
Causal Role ◽  
Central Question ◽  
Agent Causation ◽  
The Right

This chapter lays out the book’s central question: Assuming agency reductionism—that is, the thesis that the causal role of the agent in all agential activities is reducible to the causal role of states and events involving the agent—is it possible to construct a defensible model of libertarianism? It is explained that most think the answer is negative and this is because they think libertarians must embrace some form of agent-causation in order to address the problems of luck and enhanced control. The thesis of the book is that these philosophers are mistaken: it is possible to construct a libertarian model of free will and moral responsibility within an agency reductionist framework that silences that central objections to libertarianism by simply taking the best compatibilist model of freedom and adding indeterminism in the right junctures of human agency. A brief summary of the chapters to follow is given.

The Politics of Global Health Inequalities

2019 ◽  
pp. 58-84
Author(s):  
Yusra Ribhi Shawar ◽  
Jennifer Prah Ruger
Keyword(s):  
Social Sciences ◽  
Critical Theory ◽  
Global Health ◽  
Health Inequalities ◽  
Health Inequality ◽  
The Political ◽  
State Of Health ◽  
Political Determinants ◽  
The Social

Careful investigations of the political determinants of health that include the role of power in health inequalities—systematic differences in health achievements among different population groups—are increasing but remain inadequate. Historically, much of the research examining health inequalities has been influenced by biomedical perspectives and focused, as such, on ‘downstream’ factors. More recently, there has been greater recognition of more ‘distal’ and ‘upstream’ drivers of health inequalities, including the impacts of power as expressed by actors, as well as embedded in societal structures, institutions, and processes. The goal of this chapter is to examine how power has been conceptualised and analysed to date in relation to health inequalities. After reviewing the state of health inequality scholarship and the emerging interest in studying power in global health, the chapter presents varied conceptualisations of power and how they are used in the literature to understand health inequalities. The chapter highlights the particular disciplinary influences in studying power across the social sciences, including anthropology, political science, and sociology, as well as cross-cutting perspectives such as critical theory and health capability. It concludes by highlighting strengths and limitations of the existing research in this area and discussing power conceptualisations and frameworks that so far have been underused in health inequalities research. This includes potential areas for future inquiry and approaches that may expand the study of as well as action on addressing health inequality.

scholarly journals Role of Virally-Encoded Deubiquitinating Enzymes in Regulation of the Virus Life Cycle

2021 ◽  
Vol 22 (9) ◽  
pp. 4438
Author(s):  
Jessica Proulx ◽  
Kathleen Borgmann ◽  
In-Woo Park
Keyword(s):  
Immune Response ◽  
Life Cycle ◽  
Deubiquitinating Enzyme ◽  
Deubiquitinating Enzymes ◽  
Antiviral Immune Response ◽  
Cellular Processes ◽  
Virus Life Cycle ◽  
Infected Cells ◽  
Dependent Processes

The ubiquitin (Ub) proteasome system (UPS) plays a pivotal role in regulation of numerous cellular processes, including innate and adaptive immune responses that are essential for restriction of the virus life cycle in the infected cells. Deubiquitination by the deubiquitinating enzyme, deubiquitinase (DUB), is a reversible molecular process to remove Ub or Ub chains from the target proteins. Deubiquitination is an integral strategy within the UPS in regulating survival and proliferation of the infecting virus and the virus-invaded cells. Many viruses in the infected cells are reported to encode viral DUB, and these vial DUBs actively disrupt cellular Ub-dependent processes to suppress host antiviral immune response, enhancing virus replication and thus proliferation. This review surveys the types of DUBs encoded by different viruses and their molecular processes for how the infecting viruses take advantage of the DUB system to evade the host immune response and expedite their replication.

scholarly journals Gut microbiota profiles and characterization of cultivable fungal isolates in IBS patients

2021 ◽  
Author(s):  
Piero Sciavilla ◽  
Francesco Strati ◽  
Monica Di Paola ◽  
Monica Modesto ◽  
Francesco Vitali ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Gut Microbiota ◽  
Healthy Subjects ◽  
Fungal Isolates ◽  
Key Points ◽  
Health Promoting ◽  
Irritable Bowel

Abstract Studies so far conducted on irritable bowel syndrome (IBS) have been focused mainly on the role of gut bacterial dysbiosis in modulating the intestinal permeability, inflammation, and motility, with consequences on the quality of life. Limited evidences showed a potential involvement of gut fungal communities. Here, the gut bacterial and fungal microbiota of a cohort of IBS patients have been characterized and compared with that of healthy subjects (HS). The IBS microbial community structure differed significantly compared to HS. In particular, we observed an enrichment of bacterial taxa involved in gut inflammation, such as Enterobacteriaceae, Streptococcus, Fusobacteria, Gemella, and Rothia, as well as depletion of health-promoting bacterial genera, such as Roseburia and Faecalibacterium. Gut microbial profiles in IBS patients differed also in accordance with constipation. Sequence analysis of the gut mycobiota showed enrichment of Saccharomycetes in IBS. Culturomics analysis of fungal isolates from feces showed enrichment of Candida spp. displaying from IBS a clonal expansion and a distinct genotypic profiles and different phenotypical features when compared to HS of Candida albicans isolates. Alongside the well-characterized gut bacterial dysbiosis in IBS, this study shed light on a yet poorly explored fungal component of the intestinal ecosystem, the gut mycobiota. Our results showed a differential fungal community in IBS compared to HS, suggesting potential for new insights on the involvement of the gut mycobiota in IBS. Key points • Comparison of gut microbiota and mycobiota between IBS and healthy subjects • Investigation of cultivable fungi in IBS and healthy subjects • Candida albicans isolates result more virulent in IBS subjects compared to healthy subjects

scholarly journals Cysteine-Rich Hydrophobin Gene Family: Genome Wide Analysis, Phylogeny and Transcript Profiling in Cordyceps militaris

2021 ◽  
Vol 22 (2) ◽  
pp. 643
Author(s):  
Xiao Li ◽  
Fen Wang ◽  
Yanyan Xu ◽  
Guijun Liu ◽  
Caihong Dong
Keyword(s):  
Life Cycle ◽  
Pathogenic Fungi ◽  
Class Ii ◽  
Cordyceps Militaris ◽  
Transcript Profiling ◽  
Saprotrophic Fungi ◽  
Genome Wide Analysis ◽  
Genome Wide ◽  
Encoding Genes

Hydrophobins are a family of small secreted proteins found exclusively in fungi, and they play various roles in the life cycle. In the present study, genome wide analysis and transcript profiling of the hydrophobin family in Cordyceps militaris, a well-known edible and medicinal mushroom, were studied. The distribution of hydrophobins in ascomycetes with different lifestyles showed that pathogenic fungi had significantly more hydrophobins than saprotrophic fungi, and class II members accounted for the majority. Phylogenetic analysis of hydrophobin proteins from the species of Cordyceps s.l. indicated that there was more variability among the class II members than class I. Only a few hydrophobin-encoding genes evolved by duplication in Cordyceps s.l., which was inconsistent with the important role of gene duplication in basidiomycetes. Different transcript patterns of four hydrophobin-encoding genes during the life cycle indicated the possible different functions for each. The transcripts of Cmhyd2, 3 and 4 can respond to light and were related with the photoreceptors. CmQHYD, with four hydrophobin II domains, was first found in C. militaris, and multi-domain hydrophobins were only distributed in the species of Cordycipitaceae and Clavicipitaceae. These results could be helpful for further function research of hydrophobins and could provide valuable information for the evolution of hydrophobins.

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