scholarly journals The Role of Salt on Food and Human Health

2020 ◽  
Author(s):  
Miguel Elias ◽  
Marta Laranjo ◽  
Ana Cristina Agulheiro-Santos ◽  
Maria Eduarda Potes
Keyword(s):  
Human Health

Role of Nutraceuticals in Health Promotion and Disease Prevention: A Review in the Indian Context

2020 ◽  
Vol 19 (2) ◽  
pp. 139-145
Author(s):  
Sheena Chhabra ◽  
Apurva Bakshi ◽  
Ravineet Kaur
Keyword(s):  
Health Promotion ◽  
Disease Prevention ◽  
Human Health ◽  
Health Issues ◽  
Scholarly Literature ◽  
Indian Context ◽  
The Impact ◽  
Immense Potential ◽  
Specific Health

Nutraceuticals have been around for quite some time. As the nomenclature suggests, they are placed somewhere between food (nutra-) and medicine (-ceuticals) in terms of their impact on human health. Researches have focused on the impact of various types of nutraceuticals on health, their efficacy in health promotion and disease prevention, and often on suitable uses of certain categories of nutraceuticals for specific health issues. However, we are still far from utilizing the immense potential of nutraceuticals for benefiting human health in a substantial manner. We review the available scholarly literature regarding the role of nutraceuticals in health promotion, their efficacy in disease prevention and the perception of nutraceuticals' health benefits by consumers. Thereafter we analyze the need for regulation of nutraceuticals and various provisions regarding the same.

scholarly journals Guild-based analysis for understanding gut microbiome in human health and diseases

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Guojun Wu ◽  
Naisi Zhao ◽  
Chenhong Zhang ◽  
Yan Y. Lam ◽  
Liping Zhao
Keyword(s):  
Gut Microbiota ◽  
Human Health ◽  
Gut Microbiome ◽  
Association Studies ◽  
Causative Role ◽  
Disease Phenotypes ◽  
Genetic Complexity ◽  
Causative Agents ◽  
Specific Health

AbstractTo demonstrate the causative role of gut microbiome in human health and diseases, we first need to identify, via next-generation sequencing, potentially important functional members associated with specific health outcomes and disease phenotypes. However, due to the strain-level genetic complexity of the gut microbiota, microbiome datasets are highly dimensional and highly sparse in nature, making it challenging to identify putative causative agents of a particular disease phenotype. Members of an ecosystem seldomly live independently from each other. Instead, they develop local interactions and form inter-member organizations to influence the ecosystem’s higher-level patterns and functions. In the ecological study of macro-organisms, members are defined as belonging to the same “guild” if they exploit the same class of resources in a similar way or work together as a coherent functional group. Translating the concept of “guild” to the study of gut microbiota, we redefine guild as a group of bacteria that show consistent co-abundant behavior and likely to work together to contribute to the same ecological function. In this opinion article, we discuss how to use guilds as the aggregation unit to reduce dimensionality and sparsity in microbiome-wide association studies for identifying candidate gut bacteria that may causatively contribute to human health and diseases.

scholarly journals Liquid–liquid phase separation in human health and diseases

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Bin Wang ◽  
Lei Zhang ◽  
Tong Dai ◽  
Ziran Qin ◽  
Huasong Lu ◽  
...  
Keyword(s):  
Phase Separation ◽  
Liquid Phase ◽  
Human Health ◽  
Essential Role ◽  
Current Knowledge ◽  
Vital Role ◽  
Liquid Phase Separation ◽  
Eukaryotic Cells ◽  
Liquid Liquid Phase Separation

AbstractEmerging evidence suggests that liquid–liquid phase separation (LLPS) represents a vital and ubiquitous phenomenon underlying the formation of membraneless organelles in eukaryotic cells (also known as biomolecular condensates or droplets). Recent studies have revealed evidences that indicate that LLPS plays a vital role in human health and diseases. In this review, we describe our current understanding of LLPS and summarize its physiological functions. We further describe the role of LLPS in the development of human diseases. Additionally, we review the recently developed methods for studying LLPS. Although LLPS research is in its infancy—but is fast-growing—it is clear that LLPS plays an essential role in the development of pathophysiological conditions. This highlights the need for an overview of the recent advances in the field to translate our current knowledge regarding LLPS into therapeutic discoveries.

scholarly journals N-Acetylcysteine (NAC): Impacts on Human Health

Antioxidants ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 967
Author(s):  
Micaely Cristina dos Santos Tenório ◽  
Nayara Gomes Graciliano ◽  
Fabiana Andréa Moura ◽  
Alane Cabral Menezes de Oliveira ◽  
Marília Oliveira Fonseca Goulart
Keyword(s):  
Human Health ◽  
Therapeutic Potential ◽  
Experimental Studies ◽  
Primary Role ◽  
Necrosis Factor Alpha ◽  
Biochemical Basis ◽  
Tnf Α ◽  
Factor Alpha ◽  
Anti Inflammatory

N-acetylcysteine (NAC) is a medicine widely used to treat paracetamol overdose and as a mucolytic compound. It has a well-established safety profile, and its toxicity is uncommon and dependent on the route of administration and high dosages. Its remarkable antioxidant and anti-inflammatory capacity is the biochemical basis used to treat several diseases related to oxidative stress and inflammation. The primary role of NAC as an antioxidant stems from its ability to increase the intracellular concentration of glutathione (GSH), which is the most crucial biothiol responsible for cellular redox imbalance. As an anti-inflammatory compound, NAC can reduce levels of tumor necrosis factor-alpha (TNF-α) and interleukins (IL-6 and IL-1β) by suppressing the activity of nuclear factor kappa B (NF-κB). Despite NAC’s relevant therapeutic potential, in several experimental studies, its effectiveness in clinical trials, addressing different pathological conditions, is still limited. Thus, the purpose of this chapter is to provide an overview of the medicinal effects and applications of NAC to human health based on current therapeutic evidence.

scholarly journals Role of Proteins and of Some Bioactive Peptides on the Nutritional Quality of Donkey Milk and Their Impact on Human Health

Beverages ◽  
2017 ◽  
Vol 3 (4) ◽  
pp. 34 ◽  
Author(s):  
Silvia Vincenzetti ◽  
Stefania Pucciarelli ◽  
Valeria Polzonetti ◽  
Paolo Polidori
Keyword(s):  
Human Health ◽  
Nutritional Quality ◽  
Bioactive Peptides ◽  
Donkey Milk

A systems biology approach to studying the role of microbes in human health

2013 ◽  
Vol 24 (1) ◽  
pp. 4-12 ◽  
Author(s):  
Ines Thiele ◽  
Almut Heinken ◽  
Ronan MT Fleming
Keyword(s):  
Systems Biology ◽  
Human Health

Zanieczyszczenie powietrza jako zagrożenie bezpieczeństwa zdrowotnego w Polsce – w świetle teorii sekurytyzacji

2021 ◽  
Vol 19 (1) ◽  
pp. 159-176
Author(s):  
Joanna Stryjek
Keyword(s):  
Air Pollution ◽  
Qualitative Analysis ◽  
Human Health ◽  
Early Stage ◽  
Security Studies ◽  
Health Security ◽  
Scientific Debate ◽  
Copenhagen School ◽  
The Eu

Nowadays, air pollution constitutes one of the most serious threats to human health and life. Poland belongs to the group of countries with the highest level of air pollution in the EU and OECD. The scale of the threat posed by air pollution shows its importance when it comes to the health security of the Polish citizens. However, the ongoing (political and scientific) debate on health security in Poland often ignores the problem of air pollution. The aim of the article is to 1) assess the threat currently posed by air pollution to health security in Poland, 2) locate the threat in the area of health security, and 3) analyse the process of transferring the problem of air pollution from the sphere of politics to the area of security, in accordance with the theory of securitization, developed by the Copenhagen School of Security Studies. Qualitative analysis of documents together with the application of the theory of securitization show that, in Poland, the state has started to play the role of an actor securitizing air pollution as an existential threat. Nevertheless, this process is at an early stage, and its further success depends, inter alia, on decisions and possibilities related to taking extraordinary measures to eliminate the threat posed by air pollution.

scholarly journals The role of protected areas in supporting human health: a call to broaden the assessment of conservation outcomes

2017 ◽  
Vol 25 ◽  
pp. 50-58 ◽  
Author(s):  
Julien Terraube ◽  
Álvaro Fernández-Llamazares ◽  
Mar Cabeza
Keyword(s):  
Protected Areas ◽  
Human Health

Role of Betalain in Human Health

2018 ◽  
pp. 97-107
Author(s):  
Erum Akbar Hussain ◽  
Zubi Sadiq ◽  
Muhammad Zia-Ul-Haq
Keyword(s):  
Human Health
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