scholarly journals Cold Atmospheric Pressure Plasma Technology for Biomedical Application

2021 ◽  
Author(s):  
Rakesh Ruchel Khanikar ◽  
Heremba Bailung
Keyword(s):  
Atmospheric Pressure ◽  
Biomedical Applications ◽  
Biomedical Application ◽  
Biological Effects ◽  
Relative Concentration ◽  
Density Measurement ◽  
Reactive Species ◽  
Gas Temperature ◽  
Plasma Technology ◽  
Plasma Parameters

Cold plasma generated in an open environment with a temperature nearly around room temperature has recently been a topic of great importance. It has unlocked the door of plasma application in a new direction: biomedical applications. Cold atmospheric pressure (CAP) plasma comprises various neutral and charged reactive species, UV radiations, electric current/fields etc., which have several impactful effects on biological matter. Some of the significant biological effects of CAP plasma are inactivation of microorganism, stimulation of cell proliferation and tissue regeneration, destruction of cells by initializing apoptosis etc. Although the detailed mechanism of action of plasma on biomaterials is still not completely understood, some basic principles are known. Studies have indicated that the reactive oxygen species and nitrogen species (ROS, RNS) play a crucial role in the observed biological effects. In this perspective, this chapter first provides a brief discussion on the fundamentals of CAP plasma and its generation methods. Then a discussion on the optical diagnostics methods to characterize the plasma is provided. Optical emission spectroscopy (OES) is used to identify the reactive species and to measure their relative concentration. Other important plasma parameters such as gas temperature, electron/excitation temperature and electron density measurement methods using OES have also been discussed. Then a discussion on the application of CAP plasma in biomedical field is provided. A thorough understanding of biochemical reaction mechanisms involving highly reactive plasma species will further improve and extend CAP plasma technology in biomedical applications.

Gas Temperature Effect on Reactive Species Generation from the Atmospheric Pressure Air Plasma

2013 ◽  
Vol 10 (8) ◽  
pp. 686-697 ◽  
Author(s):  
Ho Young Kim ◽  
Sung Kil Kang ◽  
Hyoung Cheol Kwon ◽  
Hyun Woo Lee ◽  
Jae Koo Lee
Keyword(s):  
Temperature Effect ◽  
Atmospheric Pressure ◽  
Reactive Species ◽  
Gas Temperature ◽  
Air Plasma

scholarly journals Special Issue “Plasma Technology for Biomedical Applications”

2020 ◽  
Vol 10 (4) ◽  
pp. 1524 ◽  
Author(s):  
Emilio Martines
Keyword(s):  
Low Power ◽  
Atmospheric Pressure ◽  
Biomedical Applications ◽  
Special Issue ◽  
Plasma Technology ◽  
Plasma Medicine ◽  
Atmospheric Pressure Plasmas

The use of plasmas for biomedical applications in encountering a growing interest, especially in the framework of so-called “plasma medicine”, which aims at exploiting the action of low-power, atmospheric pressure plasmas for therapeutic purposes [...]

scholarly journals Reactive species in non-equilibrium atmospheric-pressure plasmas: Generation, transport, and biological effects

2016 ◽  
Vol 630 ◽  
pp. 1-84 ◽  
Author(s):  
X. Lu ◽  
G.V. Naidis ◽  
M. Laroussi ◽  
S. Reuter ◽  
D.B. Graves ◽  
...  
Keyword(s):  
Atmospheric Pressure ◽  
Biological Effects ◽  
Reactive Species ◽  
Atmospheric Pressure Plasmas ◽  
Non Equilibrium

scholarly journals Applications of Cold Atmospheric Pressure Plasma in Dentistry

2021 ◽  
Vol 11 (5) ◽  
pp. 1975
Author(s):  
Aline C. Borges ◽  
Konstantin G. Kostov ◽  
Rodrigo S. Pessoa ◽  
Geraldo M.A. de Abreu ◽  
Gabriela de M.G. Lima ◽  
...  
Keyword(s):  
Atmospheric Pressure ◽  
Biological Effects ◽  
Atmospheric Pressure Plasma ◽  
Reactive Species ◽  
Electrically Conducting ◽  
Pressure Plasma ◽  
Cold Plasmas ◽  
Cold Atmospheric Pressure Plasma ◽  
Ultraviolet Photons ◽  
Oral Oncology

Plasma is an electrically conducting medium that responds to electric and magnetic fields. It consists of large quantities of highly reactive species, such as ions, energetic electrons, exited atoms and molecules, ultraviolet photons, and metastable and active radicals. Non-thermal or cold plasmas are partially ionized gases whose electron temperatures usually exceed several tens of thousand degrees K, while the ions and neutrals have much lower temperatures. Due to the presence of reactive species at low temperature, the biological effects of non-thermal plasmas have been studied for application in the medical area with promising results. This review outlines the application of cold atmospheric pressure plasma (CAPP) in dentistry for the control of several pathogenic microorganisms, induction of anti-inflammatory, tissue repair effects and apoptosis of cancer cells, with low toxicity to healthy cells. Therefore, CAPP has potential to be applied in many areas of dentistry such as cariology, periodontology, endodontics and oral oncology.

scholarly journals Biomedical Applications of Electromagnetic Detection: A Brief Review

Biosensors ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 225
Author(s):  
Pu Huang ◽  
Lijun Xu ◽  
Yuedong Xie
Keyword(s):  
Thermal Effects ◽  
Biomedical Applications ◽  
Biological Theory ◽  
Biomedical Application ◽  
Biological Effects ◽  
Food Preservation ◽  
Biological Mechanisms ◽  
Relevant Research ◽  
Disease Treatment ◽  
Electromagnetic Detection

This paper presents a review on the biomedical applications of electromagnetic detection in recent years. First of all, the thermal, non-thermal, and cumulative thermal effects of electromagnetic field on organism and their biological mechanisms are introduced. According to the electromagnetic biological theory, the main parameters affecting electromagnetic biological effects are frequency and intensity. This review subsequently makes a brief review about the related biomedical application of electromagnetic detection and biosensors using frequency as a clue, such as health monitoring, food preservation, and disease treatment. In addition, electromagnetic detection in combination with machine learning (ML) technology has been used in clinical diagnosis because of its powerful feature extraction capabilities. Therefore, the relevant research involving the application of ML technology to electromagnetic medical images are summarized. Finally, the future development to electromagnetic detection for biomedical applications are presented.

scholarly journals Helium Atmospheric Pressure Plasma Jet Source Treatment of White Grapes Juice for Winemaking

2021 ◽  
Vol 11 (18) ◽  
pp. 8498
Author(s):  
Ramona Huzum ◽  
Andrei Vasile Nastuta
Keyword(s):  
Atmospheric Pressure ◽  
Atmospheric Pressure Plasma ◽  
Plasma Jet ◽  
Atmospheric Pressure Plasma Jet ◽  
Gas Temperature ◽  
Plasma Parameters ◽  
Pressure Plasma ◽  
Long Term Storage ◽  
Term Storage

In the last few years, new emerging technologies to develop novel winemaking methods were reported. Most of them pointed out the need to assess the barrel aging on the wine product, fermentation process, green technologies for wine treatment for long term storage. Among these, plasma technologies at atmospheric pressure are on the way of replacing old and expensive methods for must, wine and yeast treatment, the goal being the long-term storage, aging and even decontamination of such products, and seems to meet the requirements of the winemakers. Using the principles of dielectric barrier discharge, we power up an atmospheric pressure plasma jet in helium. This plasma is used for treatment of fresh must obtained from white grapes. Our research manuscript is focused on the correlation of plasma parameters (applied voltage, plasma power, reactive species, gas temperature) with the physico-chemical properties of white must and wine (1 and 2 years old), via ultraviolet–visible and infrared spectroscopy, and colorimetry. Two types of white must were plasma treated and studied over time. The 10 W plasma source did not exceed 40 °C during treatment, the must did not suffer during thermal treatment. A higher quantity of RONS was observed during plasma-must exposure, supporting further oxidation processes. The UV-Vis and FTIR spectroscopy revealed the presence of phenols, flavones and sugar in the wine samples. Simultaneous visualization of CIE L*a*b* and RGB in color space charts allows easier understanding of wine changing in color parameters. These experimental results supporting the possible usability of atmospheric pressure plasma for winemaking.

Theoretical Study of Plasma Parameters Dependence on Gas Temperature in an Atmospheric Pressure Argon Microwave Discharge

2008 ◽  
Author(s):  
M. Pencheva ◽  
E. Benova ◽  
I. Zhelyazkov ◽  
Hans-Jürgen Hartfuss ◽  
Michel Dudeck ◽  
...  
Keyword(s):  
Atmospheric Pressure ◽  
Theoretical Study ◽  
Microwave Discharge ◽  
Gas Temperature ◽  
Plasma Parameters

Graphene and Graphene-Based Materials in Biomedical Applications

2019 ◽  
Vol 26 (38) ◽  
pp. 6834-6850 ◽  
Author(s):  
Mohammad Omaish Ansari ◽  
Kalamegam Gauthaman ◽  
Abdurahman Essa ◽  
Sidi A. Bencherif ◽  
Adnan Memic
Keyword(s):  
Tissue Engineering ◽  
Thermal Properties ◽  
Gene Delivery ◽  
Regenerative Medicine ◽  
Biomedical Research ◽  
Biomedical Applications ◽  
Biomedical Application ◽  
Two Dimensional ◽  
Drug And Gene Delivery ◽  
Biomedical Fields

: Nanobiotechnology has huge potential in the field of regenerative medicine. One of the main drivers has been the development of novel nanomaterials. One developing class of materials is graphene and its derivatives recognized for their novel properties present on the nanoscale. In particular, graphene and graphene-based nanomaterials have been shown to have excellent electrical, mechanical, optical and thermal properties. Due to these unique properties coupled with the ability to tune their biocompatibility, these nanomaterials have been propelled for various applications. Most recently, these two-dimensional nanomaterials have been widely recognized for their utility in biomedical research. In this review, a brief overview of the strategies to synthesize graphene and its derivatives are discussed. Next, the biocompatibility profile of these nanomaterials as a precursor to their biomedical application is reviewed. Finally, recent applications of graphene-based nanomaterials in various biomedical fields including tissue engineering, drug and gene delivery, biosensing and bioimaging as well as other biorelated studies are highlighted.

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