scholarly journals Antibiotics: A food safety issue

2020 ◽  
Vol 2 (2) ◽  
pp. 123-133
Author(s):  
Alina Stancu ◽  
Nicolae Suvorov
Keyword(s):  
Human Health ◽  
Large Scale ◽  
Safety Issue ◽  
Food Contamination ◽  
Animal Husbandry ◽  
Cellular Level ◽  
The Body ◽  
Negative Effects ◽  
Genetic Changes ◽  
Chemical Residues

Population growth and globalization are currently having many negative effects on the agri-food sector's ability to ensure safe and qualitative food. Use of medicines and chemicals in animal husbandry can considerably increases production and animals' resistance to disease and pests. Elevated levels of exposure to food contaminated with chemical residues from the use of antibiotics in animal husbandry and various growth hormones are very dangerous to human health. They contribute to genetic changes at the cellular level and decreased resistance of the body to viruses and bacteria. Frequent use of antibiotics may result in chemical residues in milk, meat, eggs and honey due to large-scale application of drugs in veterinary practice. In addition to its toxicity, antibiotic residues are carcinogenic and ingested in the long term lead to increased tolerance to medication against human diseases caused by deadly bacteria. Continuous monitoring of the production phase of the agri-food chain is absolutely necessary to identify the risks of contamination and reduce the use of illegal antibiotics in animal husbandry. This research aims to determine the main causes of food contamination with chemical residues and to create an overview of the negative effects that antibiotics have on human health.

Pre-clinical study of complex phyto-sorbents on the basis of makley and chitozan

2020 ◽  
Vol 1 ◽  
pp. 52-56
Author(s):  
V.A. Baryshev ◽  
◽  
O.S. Popova ◽  
Keyword(s):  
Quality Of Life ◽  
Antimicrobial Activity ◽  
Animal Husbandry ◽  
The Body ◽  
Agricultural Products ◽  
Negative Effects ◽  
Subacute Toxicity ◽  
Poultry Farming

The aim of our research was to assess the toxicity of complex phytosorbents based on maklea cordate and chitosan. Evaluation of antimicrobial activity in vitro was carried out according to the General Pharmacopoeia Monograph (the method is described in the Pharmacopoeia (OFS.1.2.4.0010.15), three types of phytosorption complex were used as the material for the study. Phytosorbents were included in samples 1–3. In addition to sorbents, sample No. 1, oil of oregano and thyme containing carvacrol (with proven antimicrobial activity in previous experi-ments) was added, compound Macleaya cor-data was added to compound No. 2, and chi-tosan was added to compound No. 3-components of samples 1. Нe study of the toxicity of the studied parameters was stud-ied according to the guidelines [5]. The haz-ard class of the studied drugs was deter-mined according to GOST 12.1.007-76. Ac-cording to experiments, drugs can be classi-fied as low-hazard substances. Assessment of acute and subacute toxicity proved the absence of negative effects of both drugs on the body of laboratory ani-mals, at a dose twice and four times the rec-ommended therapeutic, which is 6000 mg / goal. and 12000 mg / goal., Do not cause toxic effects and death of animals. And the introduction of complexes with chitosan and macklea, at a dose of 6000 mg / goal. within 28 days, positively affects the body of labor-atory rats. That allows research to determine the effectiveness, including on productive animals. Factors that determine the relevance of the development of highly effective phytobi-otics and their use in animal husbandry and poultry farming should also include the high profitability of the production of environ-mentally friendly agricultural products and the task of improving the quality of life of the population.

Gut microbiota

2018 ◽  
pp. 202-208
Author(s):  
А.А. Пальцын
Keyword(s):  
Human Health ◽  
Food Industry ◽  
Large Scale ◽  
Human Microbiome ◽  
Intestinal Bacteria ◽  
The Body ◽  
Bacterial Cells ◽  
Prevention And Treatment ◽  
Living Nature ◽  
Amount Of Knowledge

Совершенствование методов генетического анализа и развернувшиеся на этой основе работы по международному проекту «Микробиом человека» представили большой объем знаний, существенно меняющих представления об эволюции живой природы и о механизмах развития многих болезней. Пришло осознание факта, что здоровье и болезни человека в большой степени определяются взаимодействием его собственных клеток с населяющими его тело (прежде всего кишечник) микробными (прежде всего бактериальными) клетками. Главенство в этом вопросе бактерий кишечника объясняется их подавляющей многочисленностью, позицией на первичном рубеже обмена со средой и невозможностью жизни без этого обмена. Результаты обширных теоретических и клинических исследований уже сегодня могут стать основой профилактики и терапии некоторых незаразных пандемий современности. Однако научно вполне достижимый дальнейший масштабный успех в преодолении этих пандемий тормозится внешними причинами. Кишечная микробиота связывает здоровье людей с экологией планеты, с сельским хозяйством и пищевой промышленностью. Действия же международных корпораций направляются интересами не здравоохранения, а получения максимальной выгоды в минимальные сроки. Improving methods of genetic analysis and the work developed on this basis under the «Human Microbiome» international project presented a large amount of knowledge that has significantly changed ideas about the evolution of living nature and mechanisms underlying development of many diseases. People became aware of the fact that human health and diseases are largely determined by the interaction of the body’s own cells with the microbial (primarily bacterial) cells inhabiting the body (primarily the intestine). The dominance of intestinal bacteria in this aspect is explained by their overwhelming multiplicity, position on the primary border of exchange with the environment, and the impossibility of life without this exchange. Results of extensive theoretical and clinical research already today can become a basis for prevention and treatment of some current non-infectious pandemics. However, although further, large-scale success in overcoming these pandemics is scientifically quite achievable, certain political reasons hamper it. Intestinal microbiota connects human health with the global ecology, agriculture, and the food industry while actions of governments and international corporations are driven by obtaining maximum benefits in the shortest possible time rather than interests of health care.

Toward improved human health: efficacy of dietary selenium on immunity at the cellular level

2021 ◽  
Author(s):  
xiaojing xia ◽  
Xiulin Zhang ◽  
Mingcheng Liu ◽  
Mingyuan Duan ◽  
Shanshan Zhang ◽  
...  
Keyword(s):  
Trace Element ◽  
Human Health ◽  
Cellular Level ◽  
The Body ◽  
Biological Processes ◽  
Essential Trace Element ◽  
Dietary Selenium

Selenium, an essential trace element in the body, participates in various biological processes in the form of selenoproteins. In humans, a suitable concentration of selenium is essential for maintaining normal...

scholarly journals The Sources, Synthesis and Biological Actions of Omega-3 and Omega-6 Fatty Acids in Red Meat: An Overview

Foods ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1358
Author(s):  
Eric N. Ponnampalam ◽  
Andrew J. Sinclair ◽  
Benjamin W. B. Holman
Keyword(s):  
Fatty Acids ◽  
Human Health ◽  
Crop Production ◽  
Large Scale ◽  
The Body ◽  
Short Chain ◽  
Farm Animals ◽  
Omega 3 ◽  
Health And Wellbeing ◽  
Omega 6

The maximisation of available resources for animal production, food security and maintenance of human–animal wellbeing is important for an economically viable, resilient and sustainable future. Pasture and forage diets are common sources of short chain omega-3 (n-3) polyunsaturated fatty acids (PUFA), while grain-based and feedlot diets are common sources of short chain omega-6 (n-6) PUFA. Animals deposit n-3 and n-6 PUFA as a result of their direct consumption, as feeds or by synthesis of longer chain PUFA from short chain FA precursors in the body via desaturation and elongation processes. Research conducted over the last three decades has determined that the consumption of n-3 PUFA can improve the health and wellbeing of humans through its biological, biochemical, pathological and pharmacological effects. n-6 PUFA also play an important role in human health, but when consumed at high levels, are potentially harmful. Research shows that current consumption of n-6 PUFA by the human population is high due to their meal choices and the supplied food types. If consumption of n-3 PUFA from land- and marine-based foods improves human health, it is likely that these same food types can improve the health and wellbeing of livestock (farm animals) by likewise enhancing the levels of the n-3 PUFA in their circulatory and tissue systems. Modern agricultural systems and advanced technologies have fostered large scale animal and crop production systems. These allow for the utilisation of plant concentrate-based diets to increase the rate of animal growth, often based on economics, and these diets are believed to contribute to unfavourable FA intakes. Knowledge of the risks associated with consuming foods that have greater concentration of n-6 PUFA may lead to health-conscious consumers avoiding or minimising their intake of animal- and plant-based foods. For this reason, there is scope to produce food from plant and animal origins that contain lesser amounts of n-6 PUFA and greater amounts of n-3 PUFA, the outcome of which could improve both animal and human health, wellbeing and resilience to disease.

scholarly journals Empirical and computational innovative methods for the study of health in the educational process

2019 ◽  
Vol 1 (II) ◽  
pp. 34-43
Author(s):  
Марія ГОНЧАРЕНКО ◽  
Татьяна БОГОМАЗ
Keyword(s):  
Human Health ◽  
Information Structure ◽  
Computer Software ◽  
Cellular Level ◽  
The State ◽  
Educational Process ◽  
The Body ◽  
Software Systems ◽  
Student Groups ◽  
Modern Computer

In determining the state of human health, methods of empirical research and modern computer technologies are used. Nowadays, the science of valeology is developing, where human health is considered as a harmonious combination of physical, mental, emotional, intellectual, social, environmental and spiritual health. The Department of valeology in V.N. Karazin Kharkiv National University developed a system of diagnosis of health, which allows you to monitor the state of the body from the cellular level, the level of systems and organs, to the level of energy component, as well as to determine the psycho-physiological and adaptive characteristics of the body. Monitoring is carried out with the help of instrument - computer software systems, developed on the basis of the latest achievements of science and technology, based on modern ideas about man as a complex material and energy-information structure. The diagnosis system is noninvasive, which makes it possible to use it in children's and student groups in the pedagogical process, as well as to determine the level of health and correction of post-traumatic syndrome.

scholarly journals Mobile telephony and its effects on human health

2019 ◽  
pp. 225-234
Author(s):  
Andrzej Magiera ◽  
Jolanta Solecka
Keyword(s):  
Electromagnetic Radiation ◽  
Human Health ◽  
Mobile Phones ◽  
Brain Activity ◽  
The Body ◽  
Base Stations ◽  
Mobile Telephony ◽  
International Agency ◽  
Negative Effects ◽  
The Impact

In recent years, there has been a rapid increase in the number of electromagnetic radiation sources such as mobile phones and base stations of mobile telephony. This radiation has been classified by the International Agency for Research on Cancer as a possible human carcinogen (group 2B). For this reason, many studies have been carried out on the impact of mobile telephony on human health. The largest of the experiments were carried out on animals. Due to the divergent results of many studies, there was no clear answer on the possible carcinogenic effects of this type of radiation on health. Detection of cancer shortly after an exposure is the most difficult task in analyzing the results. Some of the studies require repetition and verification of the results. In the case of negative effects of electromagnetic fields on brain activity, sleep, heart rate, cognitive function and blood pressure, no consistent evidence has been obtained either. In view of the increasing popularity of mobile phones, their location at short distances from the body (mainly the head) and the development of mobile phone technologies (which entails an increase in the number of base stations), further research, especially among young people, is needed. The duration of human exposure to electromagnetic radiation is subject to an increase and only further research can provide an answer on the possible negative effects of mobile phones and base stations.

Mechanisms of Head Injury During High-Rate Blast and Blunt Impact Events

2010 ◽  
Author(s):  
Reuben Kraft
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Blast Wave ◽  
Large Scale ◽  
Cellular Level ◽  
The Body ◽  
High Rate ◽  
Blunt Impact ◽  
Simulation Based ◽  
Impact Events

Blasts and blunt impacts are clearly large-scale phenomena, yet traumatic brain injury (TBI) occurs at a cellular or sub-cellular level. A number of hypotheses have been offered as the root causes of TBI including mechanical insults due to reverberations inside the skull following the primary blast wave, secondary and tertiary blast injury due to impact from projectiles and individuals thrown by the blast wave, vascular pressure resulting from a blast wave to the body extremities and electromagnetic radiation [1,2]. There is anecdotal information that supports, as well as contradicts, each of these hypotheses. In this work, a simulation-based framework is developed to help elucidate the mechanisms of traumatic brain injury.

scholarly journals Detoxication agents and technologies for animal husbandry under conditions of anthropogenic pollution

2020 ◽  
Vol 27 ◽  
pp. 00018
Author(s):  
Lyubov L. Zakharova ◽  
Georgiy A. Zhorov ◽  
Vasiliy I. Dorozhkin ◽  
Viktor N. Obryvin ◽  
Natalya A. Brichko
Keyword(s):  
Animal Husbandry ◽  
Anthropogenic Pollution ◽  
Feed Additives ◽  
The Body ◽  
Farm Animals ◽  
Negative Effects ◽  
Human Economic Activity ◽  
Cadmium Lead ◽  
Livestock Products ◽  
The Impact

The impact of human economic activity on the environment is increasingly taking the form of combined pollution with various ecotoxicants including xenobiotics of radiation (caesium-137, strontium-90) and chemical (mercury, cadmium, lead and other toxic elements) nature. Today, this is one of the most urgent and insufficiently studied scientific problems. At current levels of systematic intake and accumulation of ecotoxicants in the body of productive animals, various anthropogenic and environmental organopathologies and diseases develop, and the risk of obtaining products that are dangerous to the consumer increases. In this regard, in the conditions of combined technogenic pollution of agroecosystems, it is necessary to solve the problem of ensuring the production of safe and biologically complete livestock products and maintaining the health and useful qualities of farm animals. The article presents the results of research on the development of compositions and technologies for the use of sorption-detoxifying complexes in the form of feed additives to reduce the accumulation and negative effects of ecotoxicants on the animal body and ensure the production of safe products.

Inspector Quadro - the complex of preparation for the treatment of ectoand endoparasitoses in cats and dogs

2018 ◽  
Vol 12 (2) ◽  
pp. 75-84
Author(s):  
M.V. Arisov ◽  
I.P. Belykh ◽  
V.V. Artemov
Keyword(s):  
Body Weight ◽  
Clinical Picture ◽  
High Efficiency ◽  
The Body ◽  
Negative Effects ◽  
Laboratory Methods ◽  
Diagnosis Of Infection

The purpose of the research: the study of the efficacy of the preparations for veterinary use "Inspector Quadro C" and "Inspector Quadro K" against ecto- and endoparasitoses of dogs and cats. Materials and methods. Studies were conducted on spontaneously infected dogs and cats of different sexes, age, weight and breed. The diagnosis of infection with ectoparasites was made based on the clinical picture and laboratory methods of investigation (microscopy of scrapings taken from ectoparasitized skin areas, examination of the coat for fleas, lice, worms, ixodids). Infection with helminths was established by detecting eggs of helminths in faeces of animals by the method of Füleleborn and mature segments of cestodes. Preparations were applied to the animals by drip application on dry undamaged skin in places inaccessible to licking in a dose of 0.1-0.4 ml per 1 kg of body weight. The results were statistically processed. Results and discussion. "Inspector Quadro S" and "Inspector Quadro K" showed 100% efficacy at sarcoptosis in dogs, notoedrosis in cats, otodectosis in dogs and cats, ixodidoses and entomoses. "Inspector Quadro C" showed a high efficiency (92.3%) at demodecosis in dogs. However, single mites were found in one dog. 100% efficacy of "Inspector Quadro C" and "Inspector Quadro K" has been established against intestinal nematodes and cestodes in dogs and cats. Negative effects of drugs on the body of animals have not been revealed.

СОЦИАЛЬНО-ЭКОНОМИЧЕСКИЕ КОНФЛИКТЫ В РАМКАХ «КАПИТАЛИЗМА ПЛАТФОРМ»

2019 ◽  
Vol 14 (3) ◽  
pp. 33
Author(s):  
L. V. Tomin
Keyword(s):  
Large Scale ◽  
Network Effects ◽  
Corporate Control ◽  
Balance Of Power ◽  
Negative Effects ◽  
Potential Threat ◽  
Communication Infrastructure ◽  
Political Effects ◽  
Information And Communication ◽  
Integrated Information

The article is devoted to the analysis of the structure, the peculiarities of functioning and the socio-economic and political effects of the «platform capitalism». The basis of this model is the network effects produced by the integrated information and communication infrastructure, which contribute to the monopolization and the constant expansion of platform companies into new areas. The principle of functioning of this infrastructure is the continuous collection and further monetization of data extracted from the interactions of individuals among themselves or with one of the elements of a digitalized economy or government structures. Such an infrastructure — forms a potential threat of strengthening state and corporate control over citizens. In addition, the activities of platform companies produce negative effects on the labor market, reinforcing the process of precarization of employment. The integrated information and communication infrastructure of platform companies form a system of a kind of «digital Taylorism», which deprives the employee of autonomy and privacy in the workplace. The influence of digitalization, subjected to the technocratic logic of the neoliberal model of governance in democratic countries, strengthens the de-politicization of relations between the citizen and the state and further changes the balance of power between labor and capital in favor of the latter. Large-scale protests of the last years against the companies of “capitalism of platforms” demonstrated the structural contradictions of this model and formed new forms of organization and actions of grassroots workers of the “digital economy”.

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