scholarly journals Gastric Cancer Accompanying Plummer-Vinson Syndrome

Author(s):  
Ho Joon Im ◽  
Sung Eun Kim ◽  
Moo In Park ◽  
Seun Ja Park ◽  
Won Moon ◽  
...  

Plummer-Vinson syndrome (PVS), also called sideropenic dysphagia or Paterson-Kelly syndrome, is a condition characterized by a triad of chronic iron-deficiency anemia, esophageal webs, and dysphagia. This syndrome is considered as a precancerous condition due to the occurrence of squamous cell carcinoma in the hypopharynx, upper esophagus and oral cavity. Although exact data on the prevalence of the syndrome are not evidently available, physicians need to recognize this rare syndrome. Most of the patients are elderly Caucasian women aged 40 to 70 years, but cases in children, adolescents, or men have also been described. At present, the prevalence of PVS is decreasing due to improvement in nutritional habits and intake of iron supplements. Therefore, the syndrome accompanied with gastric cancer is even more uncommon. We report a case of a 61-year-old woman with PVS who was diagnosed with gastric cancer and improved after treatment.

2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Ayisha Ayisha ◽  
Sheema Masood Ali

Plummer-Vinson syndrome (PVS), also called "Paterson-Brown-Kelly syndrome“, is a rare medical syndrome generally affecting middle-aged women. Iron deficiency anemia is the prime etiological factor and other probable factors include malnutrition, genetic predisposition, or autoimmune processes characterized by three distinctive features: iron deficiency anemia, dysphagia, and esophageal web. The dysphagia is generally painless and intermittent or progressive over years, restricted to solids, and associated with weight loss. The exact pathogenesis of PVS is still indistinguishable, but it is interconnected with iron deficiency anemia. Plummer-Vinson syndrome, if left untreated, carries an increased risk of developing squamous cell carcinoma of the upper alimentary tract.In this case report, a 40-year-old female patient presented long-standing dysphagia for months, which progressively developed to postcricoid squamous cell carcinoma by the time she approached to medical treatment. Diagnosis was confirmed through laboratory tests, showing iron deficiency anemia and whole-body positron emission tomography-computed tomography (PET-CT) presenting squamous cell carcinoma in postcricoid region (hypopharynx).


2021 ◽  
Vol 64 (2) ◽  
pp. 22-25
Author(s):  
Adriana Zapata González ◽  
María Elena Uc Miam ◽  
Felipe Irineo Hernández Rosales ◽  
Alberto Mandujano González ◽  
Karime Berenice Ramos Santos

Plummer-Vinson syndrome (Paterson-Brown-Kelly) is a rare entity, characterized by dysphagia, esophageal web formation, and iron deficiency anemia. We present the case of a 46-year-old woman with a clinical history of iron deficiency anemia who subsequently presents dysphagia and odynophagia. A subcricoid web that was successfully broken with the endoscope was found. First contact doctors should be familiar with the symptoms of Plummer-Vinson syndrome, and take them into account, when addressing a patient with the classic triad. Since the syndrome is a precancerous condition with high malignant potential, early diagnosis and treatment is of utmost importance for better prognosis. Keywords: Plummer-Vinson syndrome; chronic iron deficiency anemia; esophageal membrane; squamous cell esophageal cancer; Paterson-Brown-Kelly syndrome.


2021 ◽  
pp. 1-3
Author(s):  
Mahesh S ◽  

Plummer-Vinson syndrome is a classical triad of dysphagia, iron-deficiency anemia and esophageal webs, Plummer-Vinson or Paterson-Kelly syndrome occurs. There is no exact data on the epidemiology of the condition; the syndrome is extremely rare. Most of the patients are middle-aged white women, but the syndrome has also been identified in children and adolescents in the fourth to seventh decades of life. Over the years, dysphagia is typically painless and sporadic or incremental, restricted to solids and often related to weight loss. The association with upper alimentary tract cancers is one of the most significant clinical aspects of Plummer-Vinson syndrome. Etiopathogenesis is unknown due to Plummer-Vinson syndrome.


1970 ◽  
Vol 53 (4) ◽  
pp. 791-800
Author(s):  
Gwendolyn W Pla ◽  
James C Fritz

Abstract The high incidence of iron deficiency anemia in the United States and elsewhere is caused by insufficient iron intake, plus poor utilization of many dietary sources of iron. There is need to select assimilable sources of iron for fortification of foods; animal studies show that many of the iron compounds used for cereal enrichment are poorly utilized. A method to measure availability of iron is proposed and is currently being studied collaboratively. Preliminary data indicate that in vitro solubility tests are not satisfactory to evaluate availability of iron supplements.


2019 ◽  
Vol 10 (2) ◽  
pp. 723-732 ◽  
Author(s):  
Fengzheng Gao ◽  
Wei Guo ◽  
Mingyong Zeng ◽  
Yinong Feng ◽  
Guangxin Feng

Microalgae are functional iron nutritive fortifiers that can supply more intestinal nanosized iron.


Talanta ◽  
2017 ◽  
Vol 170 ◽  
pp. 523-529 ◽  
Author(s):  
Uenderson Araujo-Barbosa ◽  
Elena Peña-Vazquez ◽  
Maria Carmen Barciela-Alonso ◽  
Sergio Luis Costa Ferreira ◽  
Ana Maria Pinto dos Santos ◽  
...  

Author(s):  
L. D Gozhaya ◽  
Tat'yana Alekseevna Egorova ◽  
T. G Isakova ◽  
O. P Goncharova ◽  
M. V Dikanova

Comprehensive assessment of galvanosis and irondeficient anemia, by the results of electrochemical, patentological, spectro-graphic, hematological studies of the oral cavity hemostasis.


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