A CRITICAL REVIEW ON MADHUMEHA JANYA TWAK-GATA VATA WITH SPECIAL REFERENCE TO DIABETIC PERIPHERAL NEURITIS

2021 ◽  
Vol 12 (4) ◽  
pp. 124-127
Author(s):  
Karishma .

With the increasing prevalence of Diabetes mellitus especially in the middle age group, the chances of developing neuro-vascular complications are very high. One such complication is Diabetic Peripheral Neuropathy / Distal Symmetric sensory Polyneuropathy (DSPN). Diabetes mellitus can be correlated to Madhumeha and its complication Peripheral neuropathy to that of Twak-gata vata. Twakgata vata is one such vatavyadhi which can manifest in a Madhumeha Rogi. According to Acharya Charaka, Prakupita vata localized in twak brings about dryness of skin, skin cracks open, numbness in that part, emaciation, black discolouration, pricking type of pain, a feeling of stretching in that part, redness, and pain in small joints. Charaka has explained the special reason for the manifestation of a vatavyadhi. He says that depending upon the specific cause and site the aggravated vata produces different types of vyadhis, like twak-gata vata, raktagata vata, etc. Though, Daha as a lakshana has not been mentioned under Twakgata vata lakshanas, when there is anubandha of vata with pitta, daha is seen. Sushruta says in rasa-rakta etc., if vata gets associated with other doshas it produces various disorders. Ex: If there is daha, then association of vata with pitta should be inferred.

Author(s):  
K. Nithesh Kumar ◽  
Sushma Katkuri ◽  
I. Ramyacharitha

Background: Type 2 diabetes mellitus is a chronic, debilitating disease characterized by insulin resistance, impaired insulin secretion and hyperglycemia. It represents more than 90% of total prevalence of diabetes in the world and is responsible for 9% of the global mortality corresponding to four million deaths per year. The objective of the study was to assess the prevalence of diabetes mellitus type-2 in a rural population of age 30 years and above.Methods: A community based cross sectional study carried out in population 30 years and above in rural area of Khammam district in Telangana during the study period from 1st January to 31st December 2015. A total of 910 persons aged 30 years or more were included in study.Results: Near about 74 (8.1%) were diagnosed as type -2 diabetes mellitus. The prevalence of DM was 16.22% in 30-40 years age group, 24.32% in 41-50 years age group, 43.34% in 51-60 years age group and 16.2% in 61-70 years age group which shows that DM increases with age and the association between age and prevalence of type 2 DM was found to be statistically significant.Conclusions: There is a need to increase awareness of type–2 diabetes mellitus in the general population. Health education should be given in terms of risk factors of diabetes. They should be made aware about early screening methods. 


2019 ◽  
Vol 7 (1) ◽  
pp. 22
Author(s):  
Gajanan Gondhali ◽  
Ashish Kundalwal ◽  
Anant A. Takalkar

Background: Peripheral polyneuropathy is most common Chronic Kidney Diseases (CKD) related complication with prevalence of more than 60%. The prevalence of peripheral neuropathy is directly proportional to duration and severity of CKD. Objective of the study was to study and assess the prevalence of peripheral neuritis and its correlates in patients with chronic kidney diseases.Methods: The present study was a cross sectional; descriptive study was conducted in October 2016 to October 2018. Data analysed by using SPSS 23.0 version.Results: Out of 90 subjects, majority were from 45-54 years age group (26). 70% were male and 30% were females. Out of 60 pre-HD patients, 33(55%) showed peripheral neuropathy. Out of 30 HD patients, 24(80%) showed peripheral neuropathy. Maximum percentage of PN seen in 45-54 age group (76.92%) amongst the 60 males 39 (65%) and amongst 30 females 18(60%) showed peripheral neuropathy. Maximum percentage of PN seen in >5 years age group (79.31%). Pure axonal sensory motor neuropathy (28.88%) was most common pattern.Conclusions: Peripheral neuropathy is very common in CKD, more common in dialysis patients as compared to predialysis patients.


Author(s):  
Muhammad Rafique ◽  
Fouzia Ishaq ◽  
Muhammad Khalid Masood ◽  
Youssef Ali Mohamad Al-Qahtani ◽  
Walaa Ibrahim Ahmed Assiri ◽  
...  

<p><strong>Abstract</strong></p><p><strong>Objective:</strong>  To determine the clinical characteristics of newly diagnosed type 1 diabetes mellitus (T1DM) in children under15 years of age. Cross sectional study conducted at Aseer Central Hospital Abha, South-western Saudi Arabia from June 2011 – May 2015.</p><p><strong>Patients and Methods:</strong><strong>  </strong>Study included 141 Saudi children, &lt; 15 years old with newly diagnosed T1DM. The demographic and laboratory data were collected from file records. The patients were divided into younger (&lt; 5 yr), middle (5 – 10 yr) and older (&gt;10 – 15 yr) age groups. Data were analyzed by using SPSS version 16.</p><p><strong>Results:</strong><strong>  </strong>Age of 141 children at onset of T1DM (mean ± SD) was 6.5 ± 3.2 years and majority 62 (44%) belonged to middle age group. Older 43 (30.5%) age group had female predominance (2:1) (p &lt; 0.0001). Diabetic ketoacidosis (DKA) (39%), obesity (11%) and male predominance (2.6:1) were found in younger 36 (25.5%) age group (p &lt; 0.0001). Family history (F/Hx) of T1DM 29 (20.6%) and HbA1c (10.36 ± 1.8%) successively increased with advancing age of patients. Main presenting symptoms like polyuria (96%), polydipsia (85%), weight loss (62%), nocturia (47%), polyphagia (28%) and DKA (22%),were significantly more frequent in children with F/Hx of T1DM (p &lt; 0.0001). Duration of symptoms at first presentation was 17.3 ± 10.7 days and daily insulin requirement was found 0.82 ± 0.2 units/ Kg.</p><p><strong>Conclusion:</strong><strong>  </strong>Polyuria, polydipsia, weight loss, noctu-ria and polyphagia were the main presenting symptoms and more frequent in middle age group children especially having F/Hx of T1DM. Under five years, obese and male children were found at higher risk for DKA development. Girls usually present late in adolescent age.</p>


2021 ◽  
pp. 1-3
Author(s):  
B.K. Kundu ◽  
Deepak Kumar ◽  
Kirandeep Kaur

Aims and Objectives: To estimate the prevalence of Diabetes Mellitus and Hypertension in the young adults of age 18-39 years, who have undergone pre-employment screening at a tertiary care hospital and document their parameters. Materials and methods: Records of all candidates of either gender belonging to the age group 18 completed years to 39 completed years, who had st th undergone pre-employment screening during the period of 1 January 2016 till 30 June 2020, preserved in the Department of Medical Examination were examined for the purpose of this study. The candidates who had been diagnosed as hypertensive or diabetic or both were tabulated. The results and values were tabulated in MS Excel. The statistical software JASPwas used for calculations. Results: Records of 12257 candidates were scrutinized, out of which 9176 were males and 3081 were females. Atotal of 182 candidates were found to be Diabetic, Hypertensive or both. Majority of the candidates were males (175 out of 182, 96.15%). The prevalence of Diabetes Mellitus was 179 and that of Hypertension was 1362 per 100,000 population. Conclusion: Diabetes and/or Hypertension are not uncommon in the young population of 18 to 39 years of age. Most of them are males. End organ affection can start early. Proper screening programmes can identify these cases early and ensure timely intervention.


2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Galawezh Othman

This study aimed to investigate the prevalence of different types of Diabetes Mellitus; the data collected from 84 patients randomly in Layla Qasem Diabetic center in Erbil city to study some genetic factors on Diabetes Mellitus disease by depend on their ages, gender, family history, Blood group and albumin in urine. In case of age average of their age was 40% between 50_60 years old and by depending on their Gender, average of genders 70% was female and 30% male in type 2, while in type 1 40% female and 60% male. The relationship between their family strain 43% of them was positive in type 2DM, and 50% positive in type 1DM. Then we compared their blood group according to our results 39 % of them was O blood group,  and in case of albumin in their urine ,in type 2 DM 35% was 30mg/l ,37% was 10mg/l, 9% was 150mg/l, and  19% was 80 mg/l .also in type 1DM 43% was 10mg/l, 11% was 150mg/l, 33% was 30 mg/l, and  13% 80mg/l . We concluded that Diabetes Mellitus in our area is more common in female than male, the percentage of the diabetes increased with age and most diabetic patients have O blood Group.


2019 ◽  
Author(s):  
hongyun qin ◽  
chengping Hu ◽  
xudong Zhao ◽  
binggen Zhu ◽  
Zhicheng Cao ◽  
...  

Abstract Objective To investigate the effect of later onset of hypertension on the progression of MCI in community. Methods Participants are from The Study (NO.PKJ2010-Y26, 2011), a population-based longitudinal cognition survey of people aged 55+, sampled by probability proportional to size cluster. Hypertension onset age was estimated by self-reported information and medical insurance card records, then classified into two groups: the middle-age group (onset age < 65 years) and the old-age group (onset age ≥ 65 years). In order to study the effect of later onset of hypertension on dementia, the incidence of dementia was compared between the two groups. Results A total of 277 hypertensive mild cognitive impairment (MCI) participants without dementia were followed for 6 years. 56 MCI participants (20.22%) progressed to dementia (MCIp). The proportion of MCIp participants in the old-age onset hypertension group (≥ 65 years) was higher than that of middle-age onset one (27.0% vs 15.4%; X2 = 5.538, P = 0.019). And in the old-age onset hypertension group, the proportion of MCIp without diabetes mellitus was higher than those with diabetes mellitus (24.7% vs 12.6%; X2 = 5.321, P = 0.021), and the proportion of MCIp with increased pulse pressure was higher than those without increased pulse pressure (33.3% vs 15.4%; X2 = 3.902, P = 0.048). However, the multivariate logistic regression analysis showed that older age was the only risk for MCIp (OR=0.732, p=0.029). Conclusions These results suggest that, later onset hypertension was harmful to cognition even in cases where the level of blood pressure maintained at 130/80mmHg with antihypertensive management. It is necessary to expand the research sample and improve the experimental methods for further confirmation.


Author(s):  
Kaushal Kumar Sinha ◽  
Abhay Kumar

Background: Diabetes is one of the commonest chronic non communicable disease affecting the society at large both in developing and developed countries. Present study aimed to study the association between different types of microvascular complications with each other and dyslipidemia  in newly diagnosed type 2 diabetes mellitus.   Subjects and Methods: In this study, 100 newly diagnosed cases of type 2 diabetes mellitus patients were evaluated. A cross section of both male and female diabetes patients diagnosed within the last 3 months (new onset) was taken into study. A detailed history, clinical examination and relevant investigations were performed. Collected data were analysed by using appropriate software. Results: In our study 60% were male and 40% were female. Majority of cases were in the age group of 46-55 years, followed by in age group 56-65 years. Association was found between Dyslipidemia and nephropathy and also between retinopathy and nephropathy. Conclusion: Endeavour should be made to control hyperglycemia and dyslipidemia tightly by appropriate therapeutic measures so that the occurrence and worsening of complications could be mitigated.


Aim:Due to the chronic nature of diabetes mellitus and its dangerous effects on people, it is moving towards epidemic proportions. We proposed this work for evaluating the predictive measure of diabetic population of India, Pakistan and world. In this work diabetic people of age 20-79 years are considered as this age group is suffering more by this disease. The aim of this study is to estimate the prevalence of diabetes in these two nations covering all the regions of the country. Materials and Methods: Mathematical analysis has been done for showing the rapid prevalence of diabetic population of age more that 20 years and less than 79 years. Karl Pearson’s coefficient of Correlation is calculated to find the relativity of prevalence of diabetic people of this age group of both the countries. Regression equations are evaluated to find the various predictive factors for the diabetic populations of countries. Results: The study represented the value of the coefficient of correlation between the diabetic population of India and Pakistan is 0.89, between India and world is 0.77 and between Pakistan and world is 0.98. All these values are positive. Conclusion: The Pearson correlation coefficient test showed that there is a positive and strong correlation between diabetic population (20-79 years age) in both the countries as well as in world. From Regression equation future prediction of increasing number of diabetic patients can be made.


2020 ◽  
Vol 11 (SPL3) ◽  
pp. 1264-1270
Author(s):  
Shreya Kothari ◽  
Rakshagan ◽  
Balaji Ganesh

Diabetes Mellitus is one of the most common metabolic disorders with 1.82 times greater risk in edentulous patients than dentate patients. It is associated with complications like neuropathy, nephropathy, retinopathy, cardiovascular problems and periodontitis. They complain of burning sensation of the mouth and multiple ulcerations in the mouth. All these problems contribute to the failure of retention of complete denture. The aim of the study is to find the prevalence of diabetes mellitus in complete denture patients. Case records of 89,000 patients who visited the hospital between June 2019- April 2020 were retrieved and reviewed. This university setting study involved 351 complete denture patients. Data was tabulated with parameters - name, age, gender, medical history of diabetes or with other systemic diseases. Data was imported to SPSS for statistical analysis. Descriptive statistics and chi-square tests were done. 26.5% of the complete denture patients had diabetes mellitus. Males were found to be slightly more prevalent than females. The most common age group affected was 60-75 years age group. Chi-square test showed no significance between age or gender with diagnosis of diabetes. ( p-value &gt;0.05). Diabetes mellitus is associated directly with edentulism with 26.5% of prevalence with this disease. The most common age group prevalent was in the age group of 60-75 years and commonly seen in males.


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