Antibacterial Activities of some Medicinal Plants Used for Treatment of Infectious Diseases in the Vina and Mayo-Louti Divisions of Cameroon

2018 ◽  
Vol 22 (3) ◽  
pp. 1-13
Author(s):  
Benjamin Talom ◽  
Siméon Fodouop ◽  
Michel Fokam ◽  
Gring Zigla ◽  
Jules-Roger Kuiate ◽  
...  
Author(s):  
Azadeh Foroughi ◽  
Pouya Pournaghi ◽  
Fariba Najafi ◽  
Akram Zangeneh ◽  
Mohammad Mahdi Zangeneh ◽  
...  

Medicinal plants are considered modern resources for producing agents that could act as alternatives to antibiotics in demeanor of antibiotic-resistant bacteria. The aim of the study was to evaluate the chemical composition and antibacterial activities of essential oil of Foeniculum vulgare (FV) against Pseudomonas aeruginosa and Bacillus subtilis. Gas chromatography mass spectrometry was done to specify chemical composion. As a screen test to detect antibacterial properties of the essential oil, agar disk and agar well diffusion methods were employed. Macrobroth tube test was performed to determinate MIC. The results indicated that the most substance found in FV essential oil was Trans-anethole (47.41 %), also the essential oil of FV with 0.007 g/ml concentration has prevented P. aeruginosa and with 0.002 g/ml concentration has prevented B. subtilis from the growth. Thus, the research represents the antibacterial effects of the medical herb on test P. aeruginosa and B. subtilis. We believe that the article provide support to the antibacterial properties of the essential oil. The results indicate the fact that the essential oil from the plant can be useful as medicinal or preservatives composition.


2020 ◽  
Vol 10 (6) ◽  
pp. 7343-7355

The purpose of our study was to bring elements of knowledge on the anticancer and antibacterial effects of two plants, widely used in Moroccan traditional pharmacopeia. These plants are: Marrubium vulgare and Euphorbia resinifera. The aerial parts of each plant were extracted successively with Hexane, Dichloromethane, and finally with methanol. The MTT-based method was applied to evaluate the cytotoxicity of the cancer cells: animal cells BSR and Vero and human cell RD. We evidenced an anticancer activity of the extract of the Marrubium vulgare and the dichloromethane extract of Euphorbia resinifera against the studied cells. The antibacterial activity was evaluated for three species of Rhodococcus: Rhodococcus equi, and strains GK1, GK3, grown in a liquid medium, or this medium solidified with agar. In the last test, the method is based on substance diffusion from well throughout the solid medium. The obtained profiles showed that the growth of bacteria is strongly inhibited by the extracts of Marrubium vulgare. However, the extracts of Euphorbia resinifera had no significant effect on bacterial growth. The chemical analysis of the raw extracts of Marrubium vulgare and Euphorbia resinifera by GC-MS analysis showed the presence of several major chemical compounds, mainly: octadecane, 2,6,10,15-tetramethylheptadecane, 2,6,10-trimethyltetradecane, linoleic acid, and deisopropylatrazine. Our observations an encouraging for deepening the studies of the extracts, in order to target better the active molecules, isolate them and to determine their mechanisms of action. The suggested studies would result in the much better valorization of these two medicinal plants.


Molecules ◽  
2019 ◽  
Vol 24 (6) ◽  
pp. 1165 ◽  
Author(s):  
Niluni Wijesundara ◽  
H. Rupasinghe

Background: There is a growing interest in medicinal plants which have been traditionally used for the treatment of human infections. This study assessed 14 ethanol extracts (EEs) on bacterial growth and biofilm formation of Streptococcus pyogenes. Methods: Constituent major phytochemicals in the extracts were identified using ultra performance liquid chromatography-electrospray ionization-tandem mass spectrometry (UPLC-ESI-MS/MS). Micro-broth dilution and time-kill assays were used to determine antibacterial activities. Anti-biofilm activities were studied using MTT assay, and morphology of biofilms was observed by scanning electron microscopy (SEM). Transmission electron microscopy (TEM) was employed to visualize the ultra-cross section structure of bacteria treated with efficacious extracts. Results: Licorice root, purple coneflower flower, purple coneflower stem, sage leaves and slippery elm inner bark EEs were the most effective, with minimum inhibitory concentrations (MIC) and minimum bactericidal concentrations (MBC) of 62.5 μg/mL and 125 μg/mL, respectively. The minimum biofilm inhibitory concentration (MBIC) of extracts ranged from 31.5–250 μg/mL. Morphological changes were observed in treated biofilms compared to the untreated. The four most effective extracts exhibited the ability to induce degradation of bacterial cell wall and disintegration of the plasma membrane. Conclusion: We suggest that EEs of sage leaf and purple coneflower flower are promising candidates to be further investigated for developing alternative natural therapies for the management of streptococcal pharyngitis.


2017 ◽  
Vol 4 (3) ◽  
pp. 1-11
Author(s):  
Rajamanickam Karthika ◽  
Packirisamy Meenatchi ◽  
Ramalingam Sundaram ◽  
Ayyakkannu Purushothaman

2015 ◽  
Vol 5 (10) ◽  
pp. 858-864 ◽  
Author(s):  
Mahmoud Bahmani ◽  
Kourosh Saki ◽  
Somayeh Shahsavari ◽  
Mahmoud Rafieian-Kopaei ◽  
Reza Sepahvand ◽  
...  

Author(s):  
Inain Jaies ◽  
Feroz Ahmad Shah ◽  
Shabir Ahmad Dar ◽  
Syed Shariq Nazir Qadiri ◽  
Asifa Wali ◽  
...  

Bacterial diseases in fishes create one of the alarming situations that render significant loss to the fishing industries and aquacultural farm units worldwide. Various drugs have been formulated, standardized, and used in the industry to combat bacterial infections. However, non-judicious drugs can lead to pharmacological problems and induction of toxicity in fishes, leaving them less suitable for human consumption. These drugs can be supplemented with the natural herb plants having antibacterial activities, although they cannot be used solely to curb the menace. Therefore, the review put forth an idea, which plant herbs can be used as antibacterial drugs in fishes.


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