Contributions of Reality TV Consumption to College Women’s Endorsement of the Heterosexual Script and Acceptance of Sexualized Aggression

A prominent feature of mainstream television, especially reality programming, is a heterosexual script that outlines women’s and men’s traditional courtship roles. Although frequent media use is believed to produce greater acceptance of this script, existing analyses have not fully delineated contributions of scripted versus reality programming or tested these notions using a holistic heterosexual script scale. We addressed these limitations in two studies. In Study 1, 466 undergraduate women indicated their support of the heterosexual script and their consumption of popular reality programs, sitcoms, and dramas. Heavier viewing of reality programming predicted greater support for the heterosexual script, and heavier viewing of sitcoms predicted weaker support. In Study 2, we used longitudinal data to explore relations between viewing reality television, acceptance of the heterosexual script, and acceptance of sexualized aggression during undergraduate women’s first 2 years in college ( N = 244). We found that reality television consumption was not a direct predictor of acceptance of sexualized aggression but was a significant, indirect predictor through endorsement of the heterosexual script. These studies contribute to our understanding of unique media contributions to endorsement of the heterosexual script and illuminate one process by which women may come to normalize sexual mistreatment. Campus educational programming on sexuality, sexual assault, and healthy relationships may be able to intervene in this normalization through critique of the heterosexual script and media portrayals of dating and relationships.

Discrete LAT condensates encode antigen information from single pMHC:TCR binding events

LAT assembly into a two-dimensional protein condensate is a prominent feature of antigen discrimination by T cells. Here, we use single-molecule imaging techniques to resolve the spatial position and temporal duration of each pMHC:TCR molecular binding event while simultaneously monitoring LAT condensation at the membrane. An individual binding event is sufficient to trigger a LAT condensate, which is self-limiting, and neither its size nor lifetime is correlated with the duration of the originating pMHC:TCR binding event. Only the probability of the LAT condensate forming is related to the pMHC:TCR binding dwell time. LAT condenses abruptly, but after an extended delay from the originating binding event. A LAT mutation that facilitates phosphorylation at the PLC-γ1 recruitment site shortens the delay time to LAT condensation and alters T cell antigen specificity. These results identify a role for the LAT protein condensation phase transition in setting antigen discrimination thresholds in T cells.

Disciplinary Power, Surveillance, and the Docile Body in Mark Dunn’s Ella Minnow Pea

Power in contemporary society is a prominent feature in literary works, especially in postmodernist literary works. Mark Dunn is an American novelist who deals with the subject of power prominently in his works, especially his first novel Ella Minnow Pea (2001). While previous studies on Dunn’s Ella Minnow Pea focused on aspects of violence, sexuality, and psychological aspects of power, this study concentrates on disciplinary aspects of power, such as surveillance, which is used to subjugate subjects without the use of violence to transform them into productive, docile bodies. The study explores Ella Minnow Pea through Foucault’s concept of disciplinary power, surveillance, and docile body. In Foucault’s view, disciplinary power is used as a conversion method to force individuals into submission to authority characterised by conformity and obedience, or docility. The study examines power manipulation, disciplinary practices, and the effectiveness of surveillance as methods for converting people into productive docile bodies and how the novel achieved this result. In addition, it delves into the characters’ responses in the novel to these machinations, which ultimately reveal that the negative impacts of repressive disciplinary power contrast with the benefits anticipated by the authoritarian state. This study provides a valuable insight on the use of Foucauldian concepts in literary criticism as the concepts chosen for this analysis have not previously been applied to this text.

BORROWINGS AS A MEANS OF COINING STYLISTIC SYNONYMS IN THE KRYMCHAK LANGUAGE

Stylistic synonymy or hendiadys (Latinized from Old Greek έν διά δυοȋν «one through two») is an important feature frequently detected in Ottoman Turkish literary standard texts. Simultaneously several scholars found it as a prominent feature of the Bible language, precisely in Old Testament. Thus, it is not surprising to find it in the fragment of Book of Daniel in Krymchak manuscript, Yosif Gabai’s jonk, dated to the early 20th century, which is in the possession of the Crimean Ethnographic Museum. As linguistic data proves, Book of Daniel probably was translated much earlier in Ottoman period and represents Hebrew-Turkic translation literature. The translator employed hendiadys by using different strategies of combination, but usually they are two nouns, or two verbs connected by a conjunction. Phrases composed by Turkic and foreign words of the same meaning or synonymic loanwords with Turkic suffixes, expressing one notion. Stylistic figures found in the manuscript are represented by following types: Turkic-Hebrew, Hebrew-Arabic, Arabic-Persian, Persian-Turkic, Arabic-Mongolian, Arabic-Turkic. Some of them could be treated as religious hendiadys. Hendyadyoin is not attested in folklore texts of Yosif Gabai’s Krymchak jonk, but in religion texts, which are variety of standard.

Mast cells differentiated in synovial fluid and resident in osteophytes exalt the inflammatory pathology of osteoarthritis

Osteophytes are a prominent feature of osteoarthritis (OA) pathology. RNA-seq of osteophytes revealed patterns corresponding to active ECM re-modulation and participation of mast cells. The cells recruitment and their activity status were confirmed by anti-TPSAB1 and anti-FC epsilon RI antibodies in immunohistochemistry. Besides subchondral bone, which is a logical yet unproven route for the cells deployment into osteophytes, the authors propose that OA synovial fluid (SF) is necessary and sufficient for maturation of mast cell precursors (MCPs) in this channel. The authors present evidences to support their claim in the form of IHC, proteomics analysis of SF samples and in vitro cell differentiation assay, wherein human monocytes (ThP1) and hematopoietic stem cells (HSCs) showed differentiation in HLA-DR+/CD206+ and FCERI+ phenotype respectively after 9 days of SF treatment. These observations expound osteophytes and resident mast cells as yet unexplained functional epicenter in OA pathology.

All Different, Yet All the Same? The Place of New Parties in Lithuanian Party System

One of the prominent feature of the Lithuanian party system is constant success of new parties. Based on political parties’ programmatic stances, this article investigates the place of these new parties in the Lithuanian party system. Using three different metrics (place in two-dimensional political spectrum, programmatic differences, nicheness), article aims at locating new parties in the party system as well as finding common denominators in party programmatic stances, which could let to assign new parties to the specific type of political parties. Analysis reveals that even though one cannot say, that all new parties are totally the same, there are common features that defines these parties (central position in the political spectrum, lack of clear programmatic niche, stressing common political issue, which separates them from traditional parties).

Resurgence, Populism, and Politics ‘From Below’

Populist politics are an increasingly prominent feature of contemporary politics around the world. In settler colonies, Indigenous resurgence is also an increasingly important feature of political contestation. Both discourses involve questions of peoplehood, pluralism, and collective agency. The goal of this paper is to explore these phenomena side by side, and ask what they reveal about the present political conjuncture. I argue that both political projects involve a constructive element, as actors build spaces of political contestation beyond the state. In this way, each movement involves an often overlooked contest between politics ‘from above’ and ‘from below’. Ultimately, I conclude that the above/below distinction reveals important cleavages that are obscured by the traditional left/right distinction that structures much political analysis.

Metabolic Reprogramming in Kidney Diseases: Evidence and Therapeutic Opportunities

Metabolic reprogramming originally referred to the ability of cancer cells to metabolically adapt to changes in environmental conditions to meet both energy consumption and proliferation requirements. According to recent studies, renal cells are also capable of reprogramming their metabolism after kidney injury, and these cells undergo different kinds of metabolic reprogramming in different kidney diseases. Metabolic reprogramming also plays a role in the progression and prognosis of kidney diseases. Therefore, metabolic reprogramming is not only a prominent feature but also an important contributor to the pathophysiology of kidney diseases. Here, we briefly review kidney diseases and metabolic reprogramming and discuss new ways to treat kidney diseases.

EBRAINS Live Papers - Interactive resource sheets for computational studies in neuroscience

We present here an online platform for sharing resources underlying publications in neuroscience. It enables authors to easily upload and distribute digital resources, such as data, code, and notebooks, in a structured and systematic way. Interactivity is a prominent feature of the Live Papers, with features to download, visualise or simulate data, models and results presented in the corresponding publications. The resources are hosted on reliable data storage servers to ensure long term availability and easy accessibility. All data are managed via the EBRAINS Knowledge Graph, thereby helping maintain data provenance, and enabling tight integration with tools and services offered under the EBRAINS ecosystem.