Applications of Nanoemulsion for the Wound-Healing Process

Attention to nanoemulsions has significantly grown in recent years as a result of their unique features like better stability, special appearance, higher performance, and sensorial merits. Chronic injuries are the consequence of a disturbance in the extremely coordinated cataract of wound healing actions. Nevertheless, correlated with variations in the timescales of various physical methods embroiled in tissue renewal, the aggression of the tumor microenvironment, rich in decaying enzymes, as well as its increased pH, demands the use of efficient drug delivery applications. This chapter summarizes that the various stages of wound healing include four phases: hemostatic stage, inflammation, proliferation, and remodeling process, respectively. Moreover, the major reported classes of lipid-based elements were either vesicular (liposome, permeation increased vesicle, etc.), emulsion-based behavior (nano-emulsion and micro-emulsion), or comprise a solid-based liquid matrix in the wound-healing process.

Medical Cyber Physical System Architecture for Smart Medical Pumps

The transformations through technological innovations have influenced the medical field. There are significant developments in medical devices in their usage. The utilization of the devices is automated in a local, remote environment. The medical devices used in the remote cyber environment uses different network protocols. These devices comprise micro, nanofabricated sensors and actuators which have the facility to communicate using network protocols. The devices that have network capability to integrate into cyberspace through physical methods are typical medical cyber physical systems (MCPS). In MCPS, medical device modelling is an important aspect. Several medical devices are available, and here in the current research, emphasis is focused on smart medical pumps in the MCPS environment. This chapter highlights the essential concepts of the smart medical drug delivery device, its architecture, control, actuation, communication, and analysis in the cyber environment.

Physical methods of motor function correction in the acute period of rehabilitation after ischemic stroke

The paper presents the data on the use of percutaneous electrical spinal cord stimulation in patients in the acute period of rehabilitation treatment after ischemic stroke. It was revealed that inclusion of percutaneous electrostimulation of the spinal cord into the rehabilitation program improves the quality of motor skills recovery and can be used in the correction of locomotor functions during rehabilitation after ischemic stroke. Key words: ischemic stroke, percutaneous electrical spinal cord stimulation.

Coronavirus Disinfection Physical Methods

Since 2019, the spread of the Coronavirus pandemic becomes the global health crisis. To fight the pandemic, several measures were adopted such as: Hygiene measure, massive test, social distancing, quarantine and distancing. Disinfection is an important operation in the fight against the spread of Corona virus pandemic. The disinfection methods are of chemical and physical type. In this work, we focused our interest to the physical methods. These methods are classified in three principal categories: irradiation techniques, heat treatment and mechanical techniques. All the different aspect of techniques are exposed in this chapter. The efficiency of the used techniques is also discussed.

Preconditioning process for dermal tissue decellularization using electroporation with sonication

Decellularization to produce bioscaffolds composed of the extracellular matrix (ECM) uses enzymatic, chemical, and physical methods to remove antigens and cellular components from tissues. Effective decellularization methods depend on the characteristics of tissues, and in particular, tissues with dense, complex structure and abundant lipid content are difficult to completely decellularize. Our study enables future research on the development of methods and treatments for fabricating bioscaffolds via decellularization of complex and rigid skin tissues, which are not commonly considered for decellularization to date as their structural and functional characteristics could not be preserved after severe decellularization. In this study, decellularization of human dermal tissue was done by a combination of both chemical (0.05% trypsin-EDTA, 2% SDS, 1% Triton X-100) and physical methods (electroporation, sonication). After decellularization, the content of DNA remaining in the tissue was quantitatively confirmed, and the structural change of the tissue and the retention and distribution of ECM components were evaluated through histological and histochemical analysis, respectively. Conditions of the chemical pretreatment that increase the efficiency of physical stimulation as well as decellularization, and conditions for electroporation and sonication without the use of detergents, unlike the methods performed in previous studies, were established to enable the complete decellularization of the skin tissue. The combinatorial decellularization treatment formed micropores in the lipid bilayers of the skin tissues while removing all cell and cellular residues without affecting the ECM properties. Therefore, this procedure can be widely used to fabricate bioscaffolds by decellularizing biological tissues with dense and complex structures.

Troubleshooting Foaming in Membrane Bioreactor: Review of Foam Analysis, Causes and Remedies

Membrane Bioreactors have proved to be a useful alternative to conventional activated sludge systems for wastewater treatment. Merits of membrane bioreactors include more compact design saving a significant amount of space and lower sludge production due to longer sludge retention time. This system unfortunately has a downside with it comes to excessive foaming. Membrane bioreactors often act as foam traps leading to overflowing, wastage of sludge and difficulty in process control. Pre-Treatment of wastewater has proven to significantly reduce foaming caused by surfactants. Generally, physical methods are considered more economical and operationally convenient compared to conventional techniques including chemical treatment and advanced techniques like biological treatment. Polyaluminium chloride as a coagulant is recommended as a chemical treatment due to economic and effectiveness considerations. It has been concluded that the remedies for foaming issue are case specific and should be determined by the causes of foaming. This paper aims at reviewing techniques to analyse the foaming phenomenon, causes of foaming and its remedies to manage or eliminate foam.

Mutual Effects of Components of Protective Films Applied on Steel in Octadecylamine and 1,2,3-Benzotriazole Vapors

In this work, we used a combination of corrosion, electrochemical, and physical methods to determine the properties of nanoscale films obtained by treatment with octadecylamine (ODA), benzotriazole (BTA) vapors, and their mixtures at elevated temperatures. The mixture of ODA + BTA surpasses its components in protective aftereffect, but an analysis of their mutual effects shows that there is antagonism between them. Electrochemical impedance spectroscopy data indicate that the protection of steel by a mixture of ODA + BTA and its components is characterized by a mixed blocking activation mechanism. The processing of steel in hot vapors of the ODA + BTA mixture leads to hydrophobization of the surface and super-hydrophobization if a polymodal surface is created on the steel before processing in vapors.