A Sensor-Based Perspective in Early-Stage Parkinson’s Disease: Current State and the Need for Machine Learning Processes

Parkinson’s disease (PD) is a progressive neurodegenerative disorder associated with dysfunction of dopaminergic neurons in the brain, lack of dopamine and the formation of abnormal Lewy body protein particles. PD is an idiopathic disease of the nervous system, characterized by motor and nonmotor manifestations without a discrete onset of symptoms until a substantial loss of neurons has already occurred, enabling early diagnosis very challenging. Sensor-based platforms have gained much attention in clinical practice screening various biological signals simultaneously and allowing researchers to quickly receive a huge number of biomarkers for diagnostic and prognostic purposes. The integration of machine learning into medical systems provides the potential for optimization of data collection, disease prediction through classification of symptoms and can strongly support data-driven clinical decisions. This work attempts to examine some of the facts and current situation of sensor-based approaches in PD diagnosis and discusses ensemble techniques using sensor-based data for developing machine learning models for personalized risk prediction. Additionally, a biosensing platform combined with clinical data processing and appropriate software is proposed in order to implement a complete diagnostic system for PD monitoring.

Cardiac Disease Prediction using Supervised Machine Learning Techniques.

Diagnosis of cardiac disease requires being more accurate, precise, and reliable. The number of death cases due to cardiac attacks is increasing exponentially day by day. Thus, practical approaches for earlier diagnosis of cardiac or heart disease are done to achieve prompt management of the disease. Various supervised machine learning techniques like K-Nearest Neighbour, Decision Tree, Logistic Regression, Naïve Bayes, and Support Vector Machine (SVM) model are used for predicting cardiac disease using a dataset that was collected from the repository of the University of California, Irvine (UCI). The results depict that Logistic Regression was better than all other supervised classifiers in terms of the performance metrics. The model is also less risky since the number of false negatives is low as compared to other models as per the confusion matrix of all the models. In addition, ensemble techniques can be approached for the accuracy improvement of the classifier. Jupyter notebook is the best tool, for the implementation of Python Programming having many types of libraries, header files, for accurate and precise work.

An effective intrusion detection system using homogeneous ensemble techniques

In this work, homogeneous ensemble techniques, namely bagging and boosting were employed for intrusion detection to determine the intrusive activities in network by monitoring the network traffic. Simultaneously, model diversity was enhanced as numerous algorithms were taken into account, thereby leading to an increase in the detection rate Several classifiers, i.e., SVM, KNN, RF, ETC and MLP) were used in case of bagging approach. Likewise, tree-based classifiers have been employed for boosting. The proposed model was tested on NSL-KDD dataset that was initially subjected to preprocessing. Accordingly, ten most significant features were identified using decision tree and recursive feature elimination method. Furthermore, the dataset was divided into five subsets, each one them being subjected to training, and the final results were obtained based on majority voting. Experimental results proved that the model was effective for detecting intrusive activities. Bagged ETC and boosted RF outperformed all the other classifiers with an accuracy of 99.123% and 99.309%, respectively.

Modelling Particulate Matter Using Multivariate and Multistep Recurrent Neural Networks

Air quality is a major problem in the world, having severe health implications. Long-term exposure to poor air quality causes pulmonary and cardiovascular diseases. Several studies have also found that deteriorating air quality also causes substantial economic losses. Thus, techniques that can forecast air quality with higher accuracy may help reduce health and economic consequences. Prior research has utilized state-of-the-art artificial neural network and recurrent neural network models for forecasting air quality. However, a comprehensive investigation of different architectures of recurrent neural network, especially LSTMs and ensemble techniques, has been less explored. Also, there have been less explorations of long-term air quality forecasts via these methods exists. This research proposes the development and calibration of recurrent neural network models and their ensemble, which can forecast air quality in terms of PM2.5 concentration 6 hours ahead in time. For forecasting air quality, a vanilla-LSTM, a stack-LSTM, a bidirectional-LSTM, a CNN-LSTM, and an ensemble of individual LSTM models were trained on the UCI Machine Learning Beijing dataset. Data were split into two parts, where 80% of data were used for training the models, while the remaining 20% were used for validating the models. For comparative analysis, four regression losses were calculated, namely root mean squared error, mean absolute percentage error, mean absolute error and Pearson’s correlation coefficient. Results revealed that among all models, the ensemble model performed the best in predicting the PM2.5 concentrations. Furthermore, the ensemble model outperformed other models reported in literature by a long margin. Among the individual models, the bidirectional-LSTM performed the best. We highlight the implications of this research on long-term forecasting of air quality via recurrent and ensemble techniques.

Verification of district level weather forecast

IMD started issuing quantitative district level weather forecast upto 5 days on operational basis from 1st June, 2008. The products comprise of quantitative forecasts for seven weather parameters, viz., rainfall, maximum and minimum temperatures, wind speed and direction, relative humidity and cloudiness. The rainfall forecast is generated based on multi model-ensemble techniques (MME). For other parameters, ECMWF forecasts (presently IMDGFS) are used. These forecast products are further value added, by the respective MCs/RMCs and forwarded to 130 Agrometeorological Field Units (AMFUs) for preparation of weather based District Agromet Advisory Service bulletin. This Meteorological Monograph describes the performance skill of the operational district level weather forecasts over different parts of India rainfall during monsoon and temperature during winter and summer from 2012-14. The Monograph also highlights limitations and future scope for further improvement of the MME models. The verification results show weather forecasts are reasonably accurate and value addition has improved the accuracy of model forecast. Though the MME model could predict the weather in hill regions in the North but in other regions having some hilly areas, the same could not come true in respect of temperature. North East region of the country shows very less accuracy due to its predominantly humid sub-tropical climate with hot, humid summers, severe monsoons and mild winter.

COVID-19 Patient Detection Based on Fusion of Transfer Learning and Fuzzy Ensemble Models Using CXR Images

The COVID-19 pandemic has claimed the lives of millions of people and put a significant strain on healthcare facilities. To combat this disease, it is necessary to monitor affected patients in a timely and cost-effective manner. In this work, CXR images were used to identify COVID-19 patients. We compiled a CXR dataset with equal number of 2313 COVID positive, pneumonia and normal CXR images and utilized various transfer learning models as base classifiers, including VGG16, GoogleNet, and Xception. The proposed methodology combines fuzzy ensemble techniques, such as Majority Voting, Sugeno Integral, and Choquet Fuzzy, and adaptively combines the decision scores of the transfer learning models to identify coronavirus infection from CXR images. The proposed fuzzy ensemble methods outperformed each individual transfer learning technique and several state-of-the-art ensemble techniques in terms of accuracy and prediction. Specifically, VGG16 + Choquet Fuzzy, GoogleNet + Choquet Fuzzy, and Xception + Choquet Fuzzy achieved accuracies of 97.04%, 98.48%, and 99.57%, respectively. The results of this work are intended to help medical practitioners achieve an earlier detection of coronavirus compared to other detection strategies, which can further save millions of lives and advantageously influence society.