ECONOMIC POTENTIAL OF THE TRADE ENTERPRISE: STRUCTURAL ASPECT

The main approaches to the classification of influencing factors of the enterprise are studied in this article. The most important types of factors that affect the activities of the enterprise are identified. The existing approaches are fully systematized. The authors offer their vision of the environment of interrelation of the main influencing factors on the economic potential.

Biophysical characterization of the homodimers of HomA and HomB, outer membrane proteins of Helicobacter pylori

Helicobacter pylori is a Gram-negative bacterium that causes chronic inflammations in the stomach area and is involved in ulcers, which can develop into gastric malignancies. H. pylori attaches and colonizes to the human epithelium using some of their outer membrane proteins (OMPs). HomB and HomA are the most studied OMPs from H. pylori as they play a crucial role in adherence, hyper biofilm formation, antibiotic resistance and are also associated with severe gastric malignancies. The role of HomA and HomB in pathogenesis concerning their structure and function has not been evaluated yet. In the present study, we explored the structural aspect of HomA and HomB proteins using various computational, biophysical and small-angle X-ray scattering (SAXS) techniques. Interestingly, the in-silico analysis revealed that HomA/B consists of 8 discontinuous N and C terminal β-strands forming a small β-barrel, along with a large surface-exposed globular domain. Further, biophysical experiments suggested that HomA and HomB are dimeric and most likely the cysteine residues present on surface-exposed loops participate in protein–protein interactions. Our study provides essential structural information of unexplored proteins of the Hom family that can help in a better understanding of H. pylori pathogenesis.

Relevant aspects to the recognition of extensional environments in the field

The understanding of each geological-structural aspect in the field is fundamental to be able to reconstruct the geological history of a region and to give a geological meaning to the data acquired in the outcrop. The description of a brittle extensional environment, which is dominated by normal fault systems, is based on: (I) image interpretation, which aims to find evidence suggestive of an extensional geological environment, such as the presence of scarp lines and fault scarps, horst, graben and/or half-graben, among others, that allow the identification of the footwall and hanging wall blocks; ii) definition of the sites of interest for testing; and iii) analysis of the outcrops, following a systematic procedure that consists of the observation and identification of the deformation markers, their three-dimensional schematic representation, and their subsequent interpretation, including the stereographic representation in the outcrop. This procedure implies the unification of the parameters of structural data acquisition in the field, mentioning the minimum fields necessary for the registration of the data in tables. Additionally, the integration of geological and structural observations of the outcrop allows to understand the nature of the geological units, the deformation related to the extensional environment and the regional tectonic context of the study area.

Kilka uwag na temat nauczania aspektu polskiego czasownika

Some Remarks On Teaching Polish Verbal Aspect. The present paper draws attention to some problems related to the teaching of the Polish verbal aspect, while also shedding light on the possible theoretical linguistic back-ground of the description of the Slavic aspect category. The author examines the category of the Slavic verbal aspect in terms of two possible approaches: cognitive linguistics and functional grammar emphasizing the importance of teaching aids: a structural aspect dictionary of the Polish verb and teaching manuals presenting the theories about the Polish verbal aspect.

The asylum–child welfare paradox: unaccompanied minors in Austria

Existing research shows that right-wing populist imaginaries and discourses on “bogus asylum seekers” mobilise feelings of fear and panic and serve to legitimise increasingly restrictive asylum policies in Europe. In light of this ongoing development, this paper addresses a more intrinsic and structural aspect of asylum, which requires balancing the inclusion and exclusion of persecuted third-country nationals. This paradox is most evident with unaccompanied minors who are caught between state norms and practices that are both exclusionary and repressive (asylum) and inclusive and caring (child welfare). In order to tackle this dilemma, we explore how the asylum–child welfare paradox is organised and formalised by the state and how it affects unaccompanied minors. Based on interviews with unaccompanied minors in Austria and experts who work with them, the findings show that child and youth welfare norms and practices that are formalised as part of the asylum procedure improve unaccompanied minors’ living conditions without dismantling asylum norms and practices of surveillance, conditionality, and scarcity. Judging by their simultaneous implementation, the state preserves and reinforces exclusionary and repressive asylum norms not despite but through child welfare norms and practices.

Pharmacological actions and underlying mechanisms of Catechin: A review

Background: Catechin is a phytochemical and is a major component of our daily use beverages, which has shown great potential in improving general health and fighting against several medical conditions. Clinical studies have confirmed its effectiveness in conditions ranging from acute upper respiratory tract infection, neuroprotection, to cardio-protection effects. Though most studies relate their potential to anti-oxidative action and radical scavenging action, still the mechanism of action is not clearly understood. Objective: The present review article is focused on addressing various pharmacological actions and underlying mechanisms of catechin. Additionally, we will try to figure out the major adverse effect and success in trials with catechin and lead to a conclusion for its effectiveness. Methods: This review article is based on the recent/ most cited papers of PubMed and Scopus databases. Description: Catechin can regulate Nrf2 and NFkB pathways in ways that impact oxidative stress and inflammation by influencing gene expression. Other pathways like MAPKs and COMT and receptor tyrosine kinase are also affected by catechin and EGCG that alter their action and barge the cellular activity. This review article explored the structural aspect of catechin and its different isomers and analogs. It also evaluated its various therapeutic and pharmacological arrays . Conclusion: Catechin and its stereo-isomers have shown their effectiveness as anti-inflammatory, anti-diabetic, anti-cancer, anti-neuroprotective, bactericidal, memory enhancer, anti-arthritis, and hepato-protective mainly through its activity to alter the pathway by NF-κB, Nrf-2, TLR4/NF-κB, COMT, and MAPKs.

Forms of ethical dilemmas in industrial-organizational psychology

Professional ethics has not been a major focus in industrial-organizational (I-O) psychology—in comparison with our study of unethical behavior in organizations. Consequently, we know very little about ethical situations actually faced by I-O psychologists. This article presents and tests a structural perspective on understanding the nature of ethical dilemmas that can facilitate such study. A taxonomy of five paradigmatic forms of ethical dilemmas is defined and placed in a theoretical context. Narrative descriptions of 292 ethical situations were obtained from a sample of 228 professional members of the Society for Industrial and Organizational Psychology (SIOP) in the United States and were used to empirically test the taxonomy. The narratives were content analyzed for form of dilemma, work domain of occurrence, relevance to human resource administration concerns, and favorability of the situation’s resolution. The work domains that were most problematic were academic research/publication activities, individual assessment/assessment centers, consulting issues regarding the client, and academic supervising/mentoring. There were no significant differences as a function of respondents’ sex, seniority, or professional membership status (member/fellow). This relatively “content free” structural aspect of ethical dilemmas enables comparisons across different domains (of professions, organizations, demographic groups, age cohorts, etc.) in which the overt idiosyncratic ethical problems experienced are not commensurable. Similarly, it can yield interpretable longitudinal comparisons despite changes in the manifestations of ethical problems encountered over time.

Effect of ‘X’ Type Bracing on Response Modification Factor for R.C. Building with Special Shaped Column Cross Sections

Earthquake is the most destructive natural hazard in the world. While designing any earthquake resistant structure, actual forces developed are much higher than designed forces. Therefore, to get design lateral force, the actual base shear force should be reduced by the factor known as response modification factor(R). Response modification factor plays vital role in seismic design of structures. Components of response modification factor (R) are ductility factor, over strength factor, redundancy factor and damping factor. Generally, value of response modification factor is adopted from seismic design codes of developed countries such as Europe, United States and India. Column is important part of Reinforced concrete building as overall load is transferred through column. Not only from aesthetical point of view, but also from structural aspect special shaped columns performs better than rectangular columns. So this study aims at calculating components of response modification factor(R) for column cross section with special shapes (L, T, +) for ‘X’ type bracing. In this study total 16 models of different number of storeys i.e. 5,10 are analysed using Pushover analysis for different seismic zones. The study also involves comparison of response modification factor (R) for structures designed with Indian code IS1893:2016(Part1) and American code ASCE 7-16.