Orbital Cellulitis in Children: Experience of the Pediatric Service at Mohammed v Military Hospital

Background: Orbital cellulitis is a diagnostic and therapeutic emergency, jeopardizing the vital and functional prognosis. This study aimed to analyze the epidemiological, therapeutic and evolutional aspects of orbital cellulitis cases treated at the pediatric service at Mohamed V military hospital. Patients and methods: retrospective study including all the children aged between 1 month and 15 years treated for orbital cellulitis at the pediatric service of the Mohamed V Hospital over a period of 3 years (1st January 2016-31st December 2019). Results: 24 cases of orbital cellulitis were gathered. Age varied between 1 month and 15 years with a median of age of 6. years. Feminine predominance (58%) was noted . The disease mainly involved the sinus (32%).Clinically, fever was present in 10 patients (41%),palpebral edema was universal, proptosis was noted in 5 cases(20.8%),chemosis and ptosis were noted in 4 cases(16.6%),bacteriological testing identified micro-organisms in 3 cases. An orbital CT scan was performed in all cases of our study, showing preseptal cellulitis in 14 cases (58.3%), orbital cellulitis in 3 cases(12.5%),and orbital abscess in 7 cases. The medical treatment consisted of ceftriaxone, metronidazole and aminoside or amoxicilline clavulanic acid, corticosteroid therapy prescribed in 5 cases. Surgical treatment was indicated in 3 patients. The outcome of All cases was favorable. Conclusion: The majority of our cases had a positive evolution highlighting the advantage of an early diagnosis, and adapted antibiotic and a multidisciplinary patient care making the need for surgery rarely necessary.

COVID-19 recovery: benefits of multidisciplinary respiratory rehabilitation

Many patients struggle with ongoing symptoms in different domains (physical, mental, cognitive) after hospitalisation for COVID-19, calling out for a multidisciplinary approach. An outpatient multidisciplinary rehabilitation programme, according to a respiratory rehabilitation strategy, was set up for adult patients who were able to attend group sessions during 12 weeks. Results of 22 adult patients with COVID-19, of which 15 had required intensive care, were analysed and some general impressions and challenges of rehabilitation in COVID-19 were reported. Impressive results on physical recovery were determined after 6 weeks and 3 months, with significant improvement of lung function, muscle force and exercise capacity variables. A positive evolution of mental and cognitive burden was present, although less pronounced than the physical recovery. These mental and cognitive consequences seem, next to musculoskeletal and medical complications, the most challenging aspect of rehabilitating patients with COVID-19. These real-world data show feasibility and efficiency of a multidisciplinary respiratory rehabilitation programme after moderate to severe COVID-19 disease.

The influence of the Zoobior remedy, used in an implementation study on the health and clinical hematological status of young hens in the first laying phase

This article presents the scientific results focused on investigating the impact of the ZooBioR remedy, obtained from Spirulina platensis, tested on young hens, in the first technological phase of laying. The research was initiated on young hens, of 24 weeks old, belonging to the “Hy-Line” hybrid, bred in identical conditions of nutrition and maintenance. The hens in the experimental group received daily food supplemented with ZooBioR, in proportion of 10 mg active substance/kg feed. During the study the birds were monitored, and periodically were determined body temperature, frequency of respiratory movements. For haematological investigations, from birds was collected blood from the axial veins and, as the case may be, from the jugular veins, in standard model test tubes. It has been established that the ZooBioR remedy is well tolerated by young hens and exhibits anti-stress and adaptive properties. In addition, the tested product has a positive evolution on the hemogram, increases the natural body resistance, inducing at the end of the study a tendency of increase of platelets in blood.

Haemodialysed patient with lung cancer in the COVID-19 era: a clinical challenge

A 66-year-old man was referred to the oncological pneumology consultation due to a mass in the right upper lobe observed in a routine X-ray of the chest. The CT scan confirmed a mass in the same location. The biopsy revealed a lung adenocarcinoma. It was decided to start chemotherapy adapted to kidney function. In April 2020, the patient contracted SARS-CoV-2 infection and developed bilateral pneumonia with partial respiratory failure. He was transferred to the intensive care unit, where he had a positive evolution. In the next 5 months, there was a clinical improvement; however, the CT scan of the chest showed disease progression. After a new multidisciplinary approach, it was decided to start a second line with atezolizumab. After four cycles of atezolizumab, there was a clear clinical improvement, and a reduction by more than 50% in the tumour size, without significant adverse effects.

KEY DETERMINANTS OF INNOVATION IN THE BANKING SECTOR

Нацеленность современной экономической системы на инновации предопределяет необходимость создания специализированной финансовой инфраструктуры «нового уровня и качества», позволяющей обеспечивать поставленные задачи инновационного развития. Эти обстоятельства в полной мере относятся к банковскому сектору, сбалансированное, устойчивое и нацеленное на положительное эволюционирование функционирование которого находится в зависимости от банковской инфраструктуры, ее количественной и, главное, качественной представленности. В связи с этим, в исследовании приводятся ряд трактовок банковской инфраструктуры, а также определены детерминанты формирования кросс-канальной банковской инфраструктуры, определяющие основные принципы стратегии развития информационных ресурсов при выведении на рынок современных банковских продуктов The focus of the modern economic system on innovation predetermines the need to create a specialized financial infrastructure "of a new level and quality", which allows to ensure theset objectives of innovative development. These circumstances fully relate to the banking sector, balanced, stable and aimed at positive evolution, the functioning of which depends on the banking infrastructure, its quantitative and, most importantly, qualitative representation. In this regard, the study provides a number of interpretations of the banking infrastructure, as well as identifies the determinants of the formation of a cross-channel banking infrastructure, which determine the basic principles of the strategy for the development of information resources when introducing modern banking products to the market.

A chromosome-level Camptotheca acuminata genome assembly provides insights into the evolutionary origin of camptothecin biosynthesis

Camptothecin and its derivatives are widely used for treating malignant tumors. Previous studies revealed only a limited number of candidate genes for camptothecin biosynthesis in Camptotheca acuminata, and it is still poorly understood how its biosynthesis of camptothecin has evolved. Here, we report a high-quality, chromosome-level C. acuminata genome assembly. We find that C. acuminata experiences an independent whole-genome duplication and numerous genes derive from it are related to camptothecin biosynthesis. Comparing with Catharanthus roseus, the loganic acid O-methyltransferase (LAMT) in C. acuminata fails to convert loganic acid into loganin. Instead, two secologanic acid synthases (SLASs) convert loganic acid to secologanic acid. The functional divergence of the LAMT gene and positive evolution of two SLAS genes, therefore, both contribute greatly to the camptothecin biosynthesis in C. acuminata. Our results emphasize the importance of high-quality genome assembly in identifying genetic changes in the evolutionary origin of a secondary metabolite.

Efficiency of a pilot scheme for the separate collection of the biowaste from municipal solid waste in Spain

According to EU regulations, member states shall take measures to encourage the recycling of biowaste in a way that fulfils a high level of environmental protection. In Spain, the separate collection of biowaste is only implemented in some regions. For this reason, a pilot scheme based on an information campaign and the location of a specific brown container for biowaste in specific zones of the city was carried out in Castelló de la Plana (Spain) over a period of six months. In this period, the collection and composition of the biowaste was monitored in depth with the goal of determining the evolution of the efficiency of the new collection system over time. In the zones, the quality rate in the biowaste container increased as the pilot study progressed, finally reaching 90%. The rate of biowaste separation also increased in the three zones over time, although in different ways, which means that there is greater collaboration on the part of citizens. On the other hand, an analysis of the rate of net biowaste daily collection from zones 2 and 3 has shown that their value increases as the rate of containerization of biowaste decreases. Therefore, to obtain better results it will be necessary to increase the containerization of biowaste, that is, to reduce the distance from the citizen to the container. It can thus be said that there is a positive evolution of the experience, which boosts confidence when it comes to implementing the system throughout the city.

The Brazilian Economy in the 1980s

Known as a lost decade, the 1980s marked several events in Brazil and other Latin American countries. Such events had a profound impact not only on the economy but also on Brazilian democracy. The Brazilian economy in the 1980s went through one of the most serious crises in its history, which resulted in the stagnation of gross domestic product and unprecedented inflation rates. Despite this critical economic situation, social indicators showed positive evolution. It was shown that, although Brazilian families adopted as a strategy to face this crisis the overuse of family work force in the labor market, the evolution of income and poverty in this period was unfavorable.

nursing care process in a user diagnosed with acinetobacter baumannii

This research work is conceived as the analysis of the nursing care process in a user with a diagnosis of Acinetobacter baumannii, for this the methodology used is descriptive, with a non-experimental qualitative approach, since a study is carried out on the records of the nursing care applied to a polytraumatized patient with a history of a car accident, admitted to the Intensive Care Unit from the operating room, and later diagnosed with infection by Acinetobacter Baumannii, for which a care plan based on NANDA taxonomies was developed , NOC and NIC emphasizing the hemodynamic and respiratory improvement, which allowed the patient to achieve a positive evolution, managing to discharge her to general hospitalization without ventilatory support.

Cómics en bibliotecas: ¿sigue mejorando su aceptación y presencia?

The aim of this article is to present the positive evolution of the presence of comics in libraries while also identifying the reasons why their effective incorporation into libraries continues to be nonuniform rather than generalized. Large comic collections are not common in Spain, and the few examples present in most centers continue to be considered a strange element among other formats. Although some misunderstanding from librarians may persist, we identify some known difficulties regarding their inclusion, including persistent problems regarding their acquisition, a preference for other formats due to budget shortfalls, and the difficulty regarding the bibliographic processing of comics. Resumen El objetivo de este trabajo es, por un lado, mostrar cómo ha evolucionado la valoración de la presencia del cómic en las bibliotecas; y, por otro, identificar algunos factores por los que su incorporación efectiva y real sigue siendo desigual y no generalizada, pues las grandes comictecas no abundan en España, y los escasos ejemplares presentes en la mayoría de los centros siguen apareciendo como un elemento extraño entre otros formatos. Al margen de que pueda seguir habiendo cierta incomprensión desde el entorno bibliotecario, identificamos algunas dificultades ya conocidas para su extensión. Entre ellas, los persistentes problemas para su adquisición; la preferencia de compra de otros formatos ante la escasez presupuestaria; y la dificultad en el tratamiento bibliotecario de los cómics con multitud de formatos difícilmente compatibles entre sí.