What role can Universities, Academia and Youth Action do to win on negotiations at Conference of Parties (COP 27) next year ?

The Climate change action is a global call to everyone across the globe, but its action and involvement is not uniform everywhere. What would be the reason? Lack of uniform applicability and universities, academia, youth role in climate action at the negotiation table alongside corporate entities and other associated stakeholders. Universities are a source of seamless dissemination of knowledge, mobilization and capacity building. The educational organizations which includes the universities and other academic institutions are a bridge programme function for leveraging the learning to corporates and in turn with unified global climate action. Universities and academic institutions are where constant exchange of knowledge happens and are facilitators to build core competencies of varied stakeholders.

Study of the surface properties of glauconite

The acid-base properties of the glauconite surface has been studied by potentiometric titration. Using a surface complexation model with a constant exchange capacity, it was shown that positively charged surface centers and exchange centers dominate in the acidic pH region, and negatively charged centers dominate in the neutral and alkaline regions. The corresponding constants of acid-base equilibrium have been calculated. The data obtained were used to study the sorption of cadmium and lead on glauconite.

BULGARIA – MY ANCIENT, YET YOUNG HOMELAND

Every teacher knows that raising a pupil is a constant exchange of thoughts and feelings between the teacher and the children. Somewhere in the process of this exchange it happens that the teacher feels the spark of the national feeling in the pupils’ souls, so he must support it with the relevant knowledge in order to ignite and intensify the feeling. The education of a worthy citizen of his country is one of the leading tasks of the preschool education. Its essence consists of the creation and implementation of a well-thought-out system of pedagogical actions, aimed at the formation of a civic consciousness and feelings in the child. The main goals in my work with the children in the group „Flame“ of kindergarten „Brezichka“ in Vratsa was to get them acquainted with the concept of the Motherland in a suitable format, to instill in them a sense of pride for their country, a desire to actively participate in public life and last, but not least – in the preservation of the Bulgarian language.

O Aurora e Prática do Sem Preço: Reflexões sobre Política, Infraestrutura e Dinheiro na Vida Ordinária

O presente artigo faz uma análise sobre o ato de pagar a partir da discussão antropológica sobre infraestrutura. Mais especificamente, se apoia em ferramentas conceituais que apontam para a dimensão ordinária, banal e invisível com a qual as infraestruturas se revelam para as pessoas em suas interações. A reflexão enriquecida por um caso empírico em que este itinerário burocrático de consumo, pagar por algo, acontece de modo diferente: trata-se de um restaurante em que a refeição não tem um preço fixo, pré-estabelecido ou mesmo sugerido. O Aurora propõe o “sem preço” como uma prática “corresponsabilização e apoio mútuo” por entenderem o valor relativo do dinheiro em nossa sociedade. O efeito de contraste que tal experiência engaja permite aprofundar nossos comprometimentos naturalizados com as lógicas de funcionamento das infraestruturas.Beyond Price at Aurora. Reflection on politics, infrastructure and money in ordinary lifeAbstract: This article analyzes the act of paying from the anthropological perspective on infrastructure. More specifically, the argument relies on its conceptual tools that point out the ordinary, banal and invisible dimension in which infrastructures are revealed to people in their daily interactions. This reflexive exercise is enriched by an empirical case that this bureaucratic consumption itinerary, paying for something, is organized in a different way: a restaurant in which the meal does not have a fixed, pre-set or even suggested price. The Aurora proposes the “sem preço” (without price) as a practice of “co-responsibility and mutual support” based on the understanding that money has different values in our society for each person. The contrasting effect this experience engages allows us to deepen the understanding about our naturalized commitments to the logic of the functioning of infrastructures through the constant exchange between materiality and ideology in which we are always agents and subjects.Keywords: Infrastructure. Daily Life. Money, Consumption. Political Action.

Microbe-Driven Genotoxicity in Gastrointestinal Carcinogenesis

The intestinal epithelium serves as a barrier to discriminate the outside from the inside and is in constant exchange with the luminal contents, including nutrients and the microbiota. Pathogens have evolved mechanisms to overcome the multiple ways of defense in the mucosa, while several members of the microbiota can exhibit pathogenic features once the healthy barrier integrity of the epithelium is disrupted. This not only leads to symptoms accompanying the acute infection but may also contribute to long-term injuries such as genomic instability, which is linked to mutations and cancer. While for Helicobacter pylori a link between infection and cancer is well established, many other bacteria and their virulence factors have only recently been linked to gastrointestinal malignancies through epidemiological as well as mechanistic studies. This review will focus on those pathogens and members of the microbiota that have been linked to genotoxicity in the context of gastric or colorectal cancer. We will address the mechanisms by which such bacteria establish contact with the gastrointestinal epithelium—either via an existing breach in the barrier or via their own virulence factors as well as the mechanisms by which they interfere with host genomic integrity.

OP0330-HPR ‘THE BEST THING WE HAVE IS EACH OTHER’ – A QUALITATIVE DYADIC APPROACH TO EXPLORE SUPPORT IN EVERYDAY LIFE BETWEEN PERSONS WITH RA AND THEIR SIGNIFICANT OTHERS

Background:Participation in everyday life and the relationships between persons with rheumatoid arthritis (RA) and their significant others are often affected by the disease. Usually, both parts need to adapt to new roles [1]. However, the dyadic interaction between them in everyday life is yet to be understood on a deeper level.Objectives:To exploreI) How dyads consisting of persons with RA and their significant others comprehend support and participation in everyday life, andII) how the dyadic interaction can influence their experience of participation in everyday life.Methods:In-depth individual interviews were conducted both with the persons with RA 12-13 years after diagnosis and inclusion in the Swedish multicenter project TIRA-2 [2], and with their significant others as defined by the persons with RA. Demographic data and the Valued Life Activity Scale (VLA-swe) [3] was reported by the persons with RA. To avoid bias, the persons with RA and their significant others were interviewed by different researches. Data from the interviews were transcribed verbatim and content analysis with a dyadic approach was undertaken [4]. The process of coding and categorizing was discussed between the researchers. The study was approved by the Regional Ethics Committee at Linköping University (Dnr. 2018/158-31), all participants gave their written consent.Results:Three women and two men with RA and five significant others, all represented by spouses, participated (N=10). The age of the persons with RA ranged from 34 to 67 years and a majority experienced difficulties in ≥ 12 valued life activities.Three categories were revealed:1) A strong willpower affecting the dyadic relationship, meaning that the understanding within the dyads was that the persons with RA were not so keen to share status, which was mentioned in connection to tenacity and expectations.2) Being a support to each other, referring to the mutual understanding within the couples that there was a constant exchange of support, forming a basis for participation in everyday life. However, disagreement was expressed concerning an unequal amount of support.3) The dyads’ potential issues with awareness, addressing the difficulty in fully comprehending the impact of the diagnosis. The couples mentioned an unwillingness from the person with RA to share information, and the significant other viewing comments as complaining. This type of miscommunication was interpreted as a potential negative effect on participation in everyday life.Conclusion:A constant exchange of support within the dyads was evident. However, the dyadic relationships were often affected by the willpower of the persons with RA to be independent in everyday life. In addition, the dyads faced the concern of fully understanding the diagnosis. The results indicate further needs for interventions for both the persons with RA as well as the significant others, in order to boost the dyadic interaction, and thereby facilitate optimal participation in everyday life of persons with RA.References:[1]Brignon M, Vioulac C, Boujut E et al. (2019) Patients and relatives coping with inflammatory arthritis: care teamwork. Health Expect 2019;00:1-11[2]Thyberg I, Dahlström Ö, Björk M, et al. (2017) Hand pains in women and men in early rheumatoid arthritis, a one year follow-up after diagnosis. The Swedish TIRA project. Disabil Rehabil 2017;39(3):291-300[3]Björk M, Thyberg M, Valtersson, E et al. (2016) Validation and internal consistency of the Swedish version of the Valued Life Activities scale. Clin Rehabil 2016;30(12):1211-1219[4]Eiskovits Z, Koren C (2010) Approaches to and outcomes of dyadic interview analysis. Qual Health Res 2010;20(12):1642-55Disclosure of Interests:None declared

Bleaching-independent, whole-cell, 3D and multi-color STED imaging with exchangeable fluorophores

We demonstrate bleaching-independent STED microscopy using fluorogenic labels that reversibly bind to their target structure. A constant exchange of labels guarantees the removal of photobleached fluorophores and their replacement by intact fluorophores, thereby circumventing bleaching-related limitations of STED super-resolution imaging in fixed and living cells. Foremost, we achieve a constant labeling density and demonstrate a fluorescence signal for long and theoretically unlimited acquisition times. Using this concept, we demonstrate whole-cell, 3D, multi-color and live cell STED microscopy with up to 100 min acquisition time.

Eurasian Transfer of Knowledge vs. Eurasian Interchange of Knowledge ―The Times Before Writing―

/Summary In light of the widely discussed issues on the modernization and industrialization of East Asia, it is sometimes overlooked that there has been a constant exchange of knowledge between East Asia and Europe. This “transfer of knowledge” during all known times was associated with the traffic of humans, animals and goods and had an input on skills and techniques, too. And it were not only goods, skills and knowledge, but religions, world views and cultures that were exchanged. Thus is it productive to speak of an “transfer of knowledge”? Is it not rather productive to speak of a constant exchange and thus of an “interchange of knowledge” - and so of a steadily ongoing process of giving and taking? So is the real question what separates East Asia and Europe or what they have in common? It is precisely this general problem that is to be pursued in a special question in time, for which there are no written sources. So it is about the earliest history, possibly even the origin of exchange processes between East and West, which can be achieved with most modern methods. Are the latest methods and results of archeology providing us with information on whether, as of when and in what areas, an exchange of knowledge between East and West existed before the time of writing? This question is being examined in a central region of the exchange, namely the “Oasis Silk Road” with the “bottle neck” of the Taklamakan. The present study / presentation is only a small, highly incomplete “florilegium” - a selection of flowers. Pilot studies with precise questions would be needed. Such preliminary investigations and pilot studies could also be made for other regions of knowledge exchange and cultural interaction in East Asia in general. On the methodical side, all methods of historiography and archeology have their specific advantages, but also their specific disadvantages. In the issue “Eurasian Interchange of Knowledge in Times before Writing”, the combined results of historiography, modern archeology, and recent natural scientific and (molecular) biological archaeology are the basis for our current state of knowledge. On the long run the different methods and results from a variety of different scientific areas have to be evaluated in their meaningfulness, reach and validity for the historiography of human action. On the basis of the results from historiography and archeology in the widest sense, can be assumed that there has been an exchange of materials, products, skills and creatures - animals and humans - since the beginning of the early agrarian culture in the Neolithic Age. Exchange processes in the widest sense in the later times of writing therefore seldom meet an almost untouched field. Rather, exchange processes usually build on existing cultural peculiarities, which are already an amalgam and thus an inseparable mixture of previous exchange processes.

Mal-estar nas organizações: por que os jovens estão abandonando o mundo corporativo?

Resumo O crescimento da rotatividade da força de trabalho brasileira nos últimos anos, em especial de suas camadas mais jovens, vem sendo motivo de preocupação de empresários e governantes. Causa de prejuízos para toda a sociedade, a alta rotatividade dos jovens é comumente explicada pela questão geracional, sendo o comportamento fugaz desses profissionais combinado a aspirações como autonomia, qualidade de vida e flexibilidade, as supostas razões para a constante troca de emprego. Contudo, muitos desses jovens fazem essa migração reiniciando suas carreiras como servidores públicos, docentes ou empreendedores, o que sugere, também, uma rejeição às carreiras nas grandes empresas privadas. Dessa maneira, neste artigo propôs-se investigar as razões que vêm afastando jovens de empresas privadas tradicionais, levando-os a abdicarem do trabalho nessas empresas para recomeçarem suas vidas profissionais em outras bases. Para atingir esse objetivo foram entrevistados 12 profissionais que já fizeram essa migração, cujas entrevistas foram analisadas por meio da análise de conteúdo. Os resultados sugerem que, contrariando parte da literatura que homogeneíza esses jovens, não há um perfil único dentro da mesma geração e essas diferenças impactam as decisões de carreira desses indivíduos. Todavia, algumas caracterizações presentes nessa mesma literatura foram corroboradas pelos achados da presente pesquisa. Ademais, o sentido do trabalho, aspecto pouco mencionado na referida literatura, emergiu como importante fator que afasta o jovem da carreira tradicional.Palavras-chave: Geração Y. Rotatividade. Sentido do trabalho. Carreira. Abstract The growth of the turnover of the Brazilian workforce in recent years, especially of its younger generation, has been of concern to entrepreneurs and government. This issue, which causes losses for the whole society, is commonly explained by the generational issue, and the elusive behavior of these professionals is combined with aspirations to autonomy, quality of life and flexibility, the alleged reasons for the constant exchange of employment. However, many of these young people do this migration restarting their careers as public employees, teachers or entrepreneurs, and it also suggests a rejection of careers in big private companies. Thus, this article aimed to investigate the reasons why young people are steping away from traditional private businesses, leading them to abdicate the work in these companies for restarting their professional lives in other bases. To achieve this goal were interviewed 12 professionals who have made this migration, whose interviews were analyzed using content analysis. The results suggest that, contrary to some of the literature that homogenizes these young people, there is no single profile within the same generation and these differences impact on the career decisions of these individuals. However, some characterizations present in this same literature were corroborated by the findings of this research. Besides, the meaning of work, aspect little mentioned in this literature, emerged as an important factor that separates the young people from the traditional career.Keywords: Generation Y. Turnover. Meaning of labor. Career.