Pesticide residues in food and potential risk of health problems : a systematic literature review

Pesticide residue in food has been investigated since the growing demand of food safe. The determination of pesticides residues in food is becomes an essential requirement for consumers, producers, and authorities responsible for food quality control. Pesticides can poison humans through the mouth, skin, and breathing. Often unwittingly these toxic chemicals enter a person’s body without causing sudden pain and causing chronic poisoning. This study aimed to investigate the impact of pesticides residue to health problems from meta-synthesize, sourced from the Scopus and Sinta indexed articles and obtained 12 indexed articles that were used as references. Meta-synthesize result showed that there are some type of pesticide who used by farmers such as chlorphenapir, emamctin benzoate, abamectin, chlorpyrifos, mankozeb, chlorotalonil, and propineb. Continous use of pesticides can cause such as fatigue, excessive saliva, hard breathing, frequent urination, blurred vision, dizzinesss, and fingerpain. At the end, pesticides residue is adverse effect on human health problems.

NEURODEGENERATIVE DISEASES: IMPACT OF PESTICIDES

Pesticides are widely used to fulfill the higher yield requirement for humans in agricultural practices and the repellents to kill the unwanted insects but excess uses of these pesticides combat various diseases and also responsible for environmental pollution. Total 234 pesticides are registered in India out of these, four pesticides are WHO class 1a pesticide, 15 are WHO class 1b pesticides, and 76 are WHO class 2nd mentioned pesticides together constituting 40% registered pesticides. Excess use of pesticides can cause fatigue, headache, respiratory problems, and neurodegenerative diseases in human being. Neurodegenerative disease is the result of a process called neuron degeneration in which the structure and functions of the neurons are progressively degenerate. Alzheimer’s, Parkinson’s, Amyotrophic lateral sclerosis impose a burden on most of society. In the present study, we are emphasizing the mode of action of the various pesticides that influenced neurodegenerative diseases that is necessary to check the effect of neurotoxicants.

Effects of Insecticides and Microbiological Contaminants on Apis mellifera Health

Over the past two decades, there has been an alarming decline in the number of honey bee colonies. This phenomenon is called Colony Collapse Disorder (CCD). Bee products play a significant role in human life and have a huge impact on agriculture, therefore bees are an economically important species. Honey has found its healing application in various sectors of human life, as well as other bee products such as royal jelly, propolis, and bee pollen. There are many putative factors of CCD, such as air pollution, GMO, viruses, or predators (such as wasps and hornets). It is, however, believed that pesticides and microorganisms play a huge role in the mass extinction of bee colonies. Insecticides are chemicals that are dangerous to both humans and the environment. They can cause enormous damage to bees’ nervous system and permanently weaken their immune system, making them vulnerable to other factors. Some of the insecticides that negatively affect bees are, for example, neonicotinoids, coumaphos, and chlorpyrifos. Microorganisms can cause various diseases in bees, weakening the health of the colony and often resulting in its extinction. Infection with microorganisms may result in the need to dispose of the entire hive to prevent the spread of pathogens to other hives. Many aspects of the impact of pesticides and microorganisms on bees are still unclear. The need to deepen knowledge in this matter is crucial, bearing in mind how important these animals are for human life.

Using a sentinel colony of Apis mellifera (Hymenoptera: Apidae) to assess pesticides and food sources.

Honey bee populations are declining as occurs with other pollinators. One suggested cause of this decline is the impact of pesticides. To improve bees’ health, pesticides and food sources may be monitored using sentinel hives, given that bees forage in a 2.5 km radius around the hive. We extracted 20 (twenty) bees, as well as samples of wax, honey and pollen from a sentinel hive. Six pesticides were detected in the samples, except for the honey. All detected pesticides in the sentinel hive are pro- hibited in Argentina. Eight different plant families and genera were detected in the honey and pollen samples. Our work suggests that monitoring pesticides with sentinel beehives will be useful to improve agricultural practices in the region.

Microbiological Nitrogen Transformations in Soil Treated with Pesticides and Their Impact on Soil Greenhouse Gas Emissions

Research was conducted in connection with the pressure exerted by man on the environment through the use of pesticides. The aim of the study was to assess the impact of pesticides on soil and to evaluate the effect of these changes on greenhouse gas emissions into the atmosphere. The research was carried out on soil sown with oilseed rape. The activity of protease and urease, ammonification, nitrification in soil, as well as CO2 (carbon dioxide) and N2O (nitrous oxide) gas emissions from soil were assessed. The analyses were carried out directly after harvest and 2 months after. Pesticides most frequently negatively affected the tested parameters, in particular enzymatic activities. Of the two herbicides used, Roundup had a stronger negative impact on microbial activity. The application of pesticides, especially the fungicide, resulted in an increase in gas emissions to the atmosphere over time. Pesticides disturbed soil environmental balance, probably interfering with qualitative and quantitative relationships of soil microorganism populations and their metabolic processes. This led to the accumulation of microbial activity products in the form of, among others, gases which contribute to the greenhouse effect by escaping from the soil into the atmosphere.

Long-term field-realistic exposure to a next-generation pesticide, flupyradifurone, impairs honey bee behaviour and survival

The assessment of pesticide risks to insect pollinators have typically focused on short-term, lethal impacts. The environmental ramifications of many of the world’s most commonly employed pesticides, such as those exhibiting systemic properties that can result in long-lasting exposure to insects, may thus be severely underestimated. Here, seven laboratories from Europe and North America performed a standardised experiment (a ring-test) to study the long-term lethal and sublethal impacts of the relatively recently approved ‘bee safe’ butenolide pesticide flupyradifurone (FPF, active ingredient in Sivanto®) on honey bees. The emerging contaminant, FPF, impaired bee survival and behaviour at field-realistic doses (down to 11 ng/bee/day, corresponding to 400 µg/kg) that were up to 101-fold lower than those reported by risk assessments (1110 ng/bee/day), despite an absence of time-reinforced toxicity. Our findings raise concerns about the chronic impact of pesticides on pollinators at a global scale and support a novel methodology for a refined risk assessment.

Side Effects of Pesticides and Metabolites in Groundwater: Impact on Denitrification

The impact of two pesticides (S-metolachlor and propiconazole) and their respective main metabolites (ESA-metolachlor and 1,2,4-triazole) on bacterial denitrification in groundwater was studied. For this, the denitrification activity and the bacterial diversity of a microbial community sampled from a nitrate-contaminated groundwater were monitored during 20 days in lab experiments in the presence or absence of pesticides or metabolites at 2 or 10 μg/L. The kinetics of nitrate reduction along with nitrite and N2O production all suggested that S-metolachlor had no or only little impact, whereas its metabolite ESA-metolachlor inhibited denitrification by 65% at 10 μg/L. Propiconazole and 1,2,4-triazole also inhibited denitrification at both concentrations, but to a lesser extent (29–38%) than ESA-metolachlor. When inhibition occurred, pesticides affected the reduction of nitrate into nitrite step. However, no significant differences were detected on the abundance of nitrate reductase narG and napA genes, suggesting an impact of pesticides/metabolites at the protein level rather than on denitrifying bacteria abundance. 16S rRNA gene Illumina sequencing indicated no major modification of bacterial diversity in the presence or absence of pesticides/metabolites, except for ESA-metolachlor and propiconazole at 10 μg/L that tended to increase or decrease Shannon and InvSimpson indices, respectively. General growth parameters suggested no impact of pesticides, except for propiconazole at 10 μg/L that partially inhibited acetate uptake and induced a decrease in microbial biomass. In conclusion, pesticides and metabolites can have side effects at environmental concentrations on microbial denitrification in groundwater and may thus affect ecosystem services based on microbial activities.