scholarly journals Per‐ and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research

2020 ◽  
Author(s):  
Suzanne E. Fenton ◽  
Alan Ducatman ◽  
Alan Boobis ◽  
Jamie C. DeWitt ◽  
Christopher Lau ◽  
...  
Keyword(s):  
Human Health ◽  
Future Research ◽  
Current State ◽  
Review Current ◽  
Health Review

scholarly journals Gambling and Social Cognition: a Systematic Review

2019 ◽  
Vol 6 (4) ◽  
pp. 547-555
Author(s):  
Elodie Hurel ◽  
Gaëlle Challet-Bouju ◽  
Nicolas Bukowski ◽  
Emeline Eyzop ◽  
Marie Grall-Bronnec
Keyword(s):  
Social Cognition ◽  
Social Information Processing ◽  
Gambling Disorder ◽  
Social Cognitive ◽  
Cognitive Remediation ◽  
Future Research ◽  
Cognitive Remediation Therapy ◽  
Current State ◽  
Neuropsychological Tasks ◽  
Review Current

Abstract Purpose of Review The aim of this article was to review current research regarding social cognition (SC) in gambling disorder (GD), to (i) compile and synthetize the current state of existing literature on this topic, and (ii) propose cognitive remediation therapy approaches focused on SC for clinicians. Recent Findings It is well known that disordered gamblers show impairment regarding non-social cognitive functions such as inhibition, attention, and decision-making. Furthermore, patients with substance use disorders also present certain deficits regarding social information processing which are difficult to differentiate from the intrinsic toxic effects linked to drugs or alcohol consumption. Summary To date, relatively little research has been undertaken to explore SC in gambling disorder (GD) with neuropsychological tasks. Preliminary results suggest impaired non-verbal emotion processing, but only one study has directly measured SC in GD. As a consequence, future research on this framework should propose diverse measures of SC, while controlling for other factors such as personality traits and subtypes of disordered gamblers.

Self-leadership Training Review

2019 ◽  
Author(s):  
Andrew Sidwell ◽  
Michael Perry
Keyword(s):  
Leadership Training ◽  
Future Research ◽  
Training Methods ◽  
Current State ◽  
A Current

The purpose of this article was to examine the current state of self-leadership training. The authors analyzed all published, publicly available studies (in English) pertaining to self-leadership training methods, offering a current state of self-leadership training, and implications for future research.

Transferrin-Conjugated Nanocarriers as Active-Targeted Drug Delivery Platforms for Cancer Therapy

2017 ◽  
Vol 23 (3) ◽  
pp. 454-466 ◽  
Author(s):  
Daniele R. Nogueira-Librelotto ◽  
Cristiane F. Codevilla ◽  
Ammad Farooqi ◽  
Clarice M. B. Rolim
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Tumor Cells ◽  
Therapeutic Benefit ◽  
Active Targeting ◽  
Future Research ◽  
Passive Targeting ◽  
The Right ◽  
Review Current ◽  
Target Effects

A lot of effort has been devoted to achieving active targeting for cancer therapy in order to reach the right cells. Hence, increasingly it is being realized that active-targeted nanocarriers notably reduce off-target effects, mainly because of targeted localization in tumors and active cellular uptake. In this context, by taking advantage of the overexpression of transferrin receptors on the surface of tumor cells, transferrin-conjugated nanodevices have been designed, in hope that the biomarker grafting would help to maximize the therapeutic benefit and to minimize the side effects. Notably, active targeting nanoparticles have shown improved therapeutic performances in different tumor models as compared to their passive targeting counterparts. In this review, current development of nano-based devices conjugated with transferrin for active tumor-targeting drug delivery are highlighted and discussed. The main objective of this review is to provide a summary of the vast types of nanomaterials that have been used to deliver different chemotherapeutics into tumor cells, and to ultimately evaluate the progression on the strategies for cancer therapy in view of the future research.

scholarly journals The fragranced products phenomenon: air quality and health, science and policy

2020 ◽  
Author(s):  
Anne Steinemann
Keyword(s):  
Air Quality ◽  
Human Health ◽  
Consumer Products ◽  
Health Science ◽  
Future Research ◽  
Research Directions ◽  
Science And Policy ◽  
New Findings ◽  
Future Research Directions ◽  
Indoor And Outdoor

Abstract Fragrance is used in consumer products around the world. However, fragrance has been associated with adverse effects on indoor and outdoor air quality and human health. Questions arise, such as the following: Why does fragrance in products pose problems? What are sources of emissions and exposures? What are health and societal effects? What are possible solutions? This paper examines the issue of fragranced consumer products and its science and policy dimensions, with a focus on the implications for air quality and human health. Results include new findings and new questions for future research directions.

From Globalisation to Revolution? The Porfirian Political Economy: An Essay on Issues and Interpretations

2009 ◽  
Vol 41 (2) ◽  
pp. 347-368 ◽  
Author(s):  
PAOLO RIGUZZI
Keyword(s):  
Political Economy ◽  
Mexican Revolution ◽  
Future Research ◽  
The Political ◽  
Economic Relations ◽  
Future Research Agenda ◽  
Current State ◽  
International Economic Relations ◽  
Economic Strategies ◽  
State Finance

AbstractThis essay evaluates the political economy of Mexico during the Porfirian period (1876–1911), with the aim of discussing advances in scholarship and presenting an outline of the elements for a future research agenda. To this end, the essay examines the current state of knowledge on four crucial aspects of the Mexican economy: growth and its dimensions; the state, finance and economic strategies; the construction and functioning of the internal market; and the international economic relations of Mexico during the first period of globalisation. In particular, it assesses the arguments that link features of Porfirian economic organisation with the outbreak of the Mexican Revolution in 1910.

A Scoping Review of Resilience in Survivors of Human Trafficking

2021 ◽  
pp. 152483802098556
Author(s):  
Logan Knight ◽  
Yitong Xin ◽  
Cecilia Mengo
Keyword(s):  
Interpersonal Relationships ◽  
Scoping Review ◽  
National Origin ◽  
Future Research ◽  
Research Needs ◽  
Standardized Measures ◽  
Factors Associated ◽  
Current State ◽  
Case Files ◽  
Sexual Trafficking

Resilience is critical among survivors of trafficking as they are mostly vulnerable populations who face multiple adversities before, during, and after trafficking. However, resilience in survivors of trafficking is understudied. This scoping review aims to clarify the current state of knowledge, focusing on definitions of resilience, how resilience has been studied, and factors associated with resilience among survivors. Five databases were searched using key words related to trafficking and resilience. Studies were included if they were published in English between 2000 and 2019 and focused on resilience with the study design including at least one of these four features: (a) use of standardized measures of resilience, (b) qualitative descriptions of resilience, (c) participants were survivors or professionals serving survivors, and (d) data sources such as case files or program manuals directly pertained to survivors. Eighteen studies were identified. Findings indicated that resilience was primarily described as emergent from interactions between the survivor and the environment. Resilience in trafficking appeared largely similar to resilience in other kinds of victimization. Nonetheless, trafficking survivors also may display resilience in alternative ways such as refusing treatment. Positive interpersonal relationships were the most commonly mentioned resilience factor. In addition, current research lacks studies featuring longitudinal designs, interventions, participatory methods, types of trafficking other than sexual trafficking, and demographic characteristics such as age, gender, and national origin. Future research needs to establish definitions and measures of resilience that are culturally and contextually relevant to survivors and build knowledge necessary for designing and evaluating resilience-enhancing interventions.

scholarly journals Hepatic stellate cells: current state and open questions

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Claus Kordes ◽  
Hans H. Bock ◽  
Doreen Reichert ◽  
Petra May ◽  
Dieter Häussinger
Keyword(s):  
Hepatic Stellate Cells ◽  
Stellate Cells ◽  
Essential Elements ◽  
Future Research ◽  
Heinrich Heine ◽  
Current State ◽  
Open Questions ◽  
Sinusoidal Endothelium ◽  
Cell Niche ◽  
Space Of Disse

Abstract This review article summarizes 20 years of our research on hepatic stellate cells within the framework of two collaborative research centers CRC575 and CRC974 at the Heinrich Heine University. Over this period, stellate cells were identified for the first time as mesenchymal stem cells of the liver, and important functions of these cells in the context of liver regeneration were discovered. Furthermore, it was determined that the space of Disse – bounded by the sinusoidal endothelium and hepatocytes – functions as a stem cell niche for stellate cells. Essential elements of this niche that control the maintenance of hepatic stellate cells have been identified alongside their impairment with age. This article aims to highlight previous studies on stellate cells and critically examine and identify open questions and future research directions.

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