Phytochemical Constituents and Pharmacological Activities of a Traditional Medicinal Plant, Glochidion eriocarpum (Phyllanthaceae)

2020 ◽  
pp. 431-441
Author(s):  
Beixi Zhang ◽  
Sizhao Liu ◽  
Qiyi Lei ◽  
Jiangju Zhou ◽  
Chunlin Long
Keyword(s):  
Medicinal Plant ◽  
Pharmacological Activities ◽  
Phytochemical Constituents

Phytochemical Profiling, Pharmacological activities, Isolation and Identification of Phytochemicals from Sterculia urens Roxb. leaves

2021 ◽  
Vol 25 (11) ◽  
pp. 11-19
Author(s):  
Chaitanya Darapureddy ◽  
K.R.S. Prasad ◽  
R.S. Ch Phani
Keyword(s):  
Phenolic Compounds ◽  
Methanolic Extract ◽  
Radical Scavenging ◽  
Diffusion Method ◽  
Spectral Studies ◽  
Clot Lysis ◽  
Inhibition Activity ◽  
Pharmacological Activities ◽  
Sterculia Urens ◽  
Phytochemical Constituents

The study is intended to evaluate the pharmacological activities, isolation and characterization of the bioactive phytochemical constituents from the crude leaf extract of Sterculia urens Roxb. The extraction of the phytochemicals from the leaves was carried on Soxhlet extraction apparatus using solvents like hexane, ethyl acetate, methanol and water. Pharmacological activities such as DPPH free radical scavenging assay (antioxidant), α-amylase inhibition assay (antidiabetic), albumin denaturation assay (antiinflammatory), blood clot lysis method (thrombolytic) and well diffusion method (antibacterial) of the crude extracts were evaluated and then the semi-preparative HPLC analysis followed by spectral studies was carried for the purification and identification of bioactive compounds. The methanolic extract showed high DPPH radical scavenging activity, α-amylase inhibition activity and albumin denaturation inhibition activity with IC50 values of 29.51±0.11, 146.85±0.18 and 149.91±0.19 μg/mL respectively. The % clot lysis of the methanolic extract was found higher than the other extracts and all the extracts have potential inhibition on the growth of the bacterial studied. From the leaf methanolic extract, 4 phenolic compounds (2,4-dihydroxybenzoic acid, methyl 4- hydroxycinnamate, p-coumaric acid and stercurensin) and 3 phenolic compounds (gossypetin, farrerol and quercetin 5,7,3',4'-tetramethyl ether) were isolated and characterised. Based on the results observed, it can be concluded that the leaf extracts of Sterculia urens Roxb are having rich phytochemical constituents with prominent pharmacological activities.

scholarly journals A Review on Ethnopharmacological Applications, Pharmacological Activities, and Bioactive Compounds ofMangifera indica(Mango)

2017 ◽  
Vol 2017 ◽  
pp. 1-24 ◽  
Author(s):  
Meran Keshawa Ediriweera ◽  
Kamani Hemamala Tennekoon ◽  
Sameera Ranganath Samarakoon
Keyword(s):  
Amino Acids ◽  
Bioactive Compounds ◽  
Mangifera Indica ◽  
Fruit Peel ◽  
Pharmacological Activities ◽  
Phytochemical Constituents ◽  
Pharmacological Potential ◽  
Diverse Plant ◽  
Different Parts ◽  
Comprehensive Study

Mangifera indica(family Anacardiaceae), commonly known as mango, is a pharmacologically, ethnomedically, and phytochemically diverse plant. Various parts ofM. indicatree have been used in traditional medicine for the treatment of different ailments, and a number of bioactive phytochemical constituents ofM. indicahave been reported, namely, polyphenols, terpenes, sterols, carotenoids, vitamins, and amino acids, and so forth. Several studies have proven the pharmacological potential of different parts of mango trees such as leaves, bark, fruit peel and flesh, roots, and flowers as anticancer, anti-inflammatory, antidiabetic, antioxidant, antibacterial, antifungal, anthelmintic, gastroprotective, hepatoprotective, immunomodulatory, antiplasmodial, and antihyperlipemic. In the present review, a comprehensive study on ethnopharmacological applications, pharmacological activities, and bioactive compounds ofM. indicahas been described.

scholarly journals Pharmacognosy, phytochemistry, pharmacology and clinical application of Ginkgo biloba

2021 ◽  
Vol 16 (2) ◽  
pp. 229-240
Author(s):  
Manisha P. More ◽  
Anuja S. Motule ◽  
Prajakta N. Dongare ◽  
Prerna A. Patinge ◽  
Rahul D. Jawarkar ◽  
...  
Keyword(s):  
Cancer Treatment ◽  
Clinical Application ◽  
Ginkgo Biloba ◽  
Ginkgolide B ◽  
Pharmacological Profile ◽  
Pharmacological Activities ◽  
Potential Source ◽  
Ginkgolide A ◽  
Phytochemical Constituents ◽  
Different Parts

In the present review, we are highlighted various pharmacognostic and pharmacological aspects of the different parts of plant Ginkgo biloba. Leaves are mainly potential source of phytochemical constituents. The plant encompasses variety of pharmacological activities namely antioxidant, hypolipidemic, antibacterial, etc. The pharmacological profile of plant is mainly attributed to the presence of chemicals such as Ginkgolide A, Ginkgolide B, Ginkgolide C, Bilobalide, Ginkgotoxin, ginkgolides and bilobalide are the major constituents. The pills with the highest concentration of plant extract (100 mg) allow the intake of the highest antioxidants concentration. It is also used along with 5-flurouracil in cancer treatment. There is need to explore more activities of the plant.

scholarly journals Kasani beej (Cichorium intybus): Ayurvedic View, Folk View, Phytochemistry and Modern Therapeutic Uses

2021 ◽  
Vol 8 (2) ◽  
pp. 114-125
Author(s):  
Shailja Choudhary ◽  
Hemlata Kaurav ◽  
Gitika Chaudhary
Keyword(s):  
Medicinal Plant ◽  
Arid Regions ◽  
Sesquiterpene Lactones ◽  
Cichorium Intybus ◽  
Vegetable Crop ◽  
Therapeutic Uses ◽  
Traditional Remedy ◽  
Coffee Substitute ◽  
Phytochemical Constituents ◽  
Asteraceae Family

Cichorium intybus is commonly known as Chicory, kasani. It is a recognized medicinal plant that belongs to the Asteraceae family. This plant is a well-known traditional herb used in various medicinal systems like Ayurveda, Unani and Siddha medicinal system to treat variety of diseases ranging from wounds to diabetes. The species is native to the European region (Mediterranean region) but can also grow in the temperate and semi-arid regions. The juice extracted from this plant is used as a traditional remedy to cure uterus cancer and tumors. The plant is well-known for its roots that are used as an additive in coffee as it provides bitterness in taste without the caffeine. It is also reported that the roots of the plant contain 40% inulin and acts as an anti-diabetic agent. Historically, the plant was cultivated by ancient Egyptians as a medicinal plant, vegetable crop, coffee substitute and also used as animal forage. Cichorium intybus contains various phytochemical constituents mainly sesquiterpene lactones, caffeic acid derivatives, inulin flavonoids, alkaloids, phenols, steroids terpenoids and many more. The reported pharmacological properties of the C. intybus plant include hepatoprotective, anti-diabetic, anti-cancerous, anti-inflammatory, analgesic, cardiovascular, antioxidant, antimicrobial, anthelmintic, antimalarial, anti-allergic and gastroprotective activities. In this review article, the medicinal and ayurvedic importance of C. intybus plant along with its phytochemicals are briefly explained.

scholarly journals Review Based Upon Ayurvedic and Traditional Uses of Cinnamomum tamala (Tejpatta)

2021 ◽  
Vol 68 (2) ◽  
Author(s):  
Shifali Thakur ◽  
Gitika Chaudhary
Keyword(s):  
Chemical Constituents ◽  
Bioactive Constituents ◽  
Pharmacological Activities ◽  
The Past ◽  
Cinnamomum Tamala ◽  
Medicinal Use ◽  
Phytochemical Compounds ◽  
Phytochemical Constituents ◽  
Herbal Plant ◽  
Flavoring Agent

Cinnamomum tamala is an evergreen plant native to Sri Lanka and India. This herbal plant is commonly called Indian cassia, Tejpatta and Indian bay leaf. There are many bioactive constituents isolated from plant Cinnamomum tamala. Leaves of the plant possess aromatic fragrance and are also utilized as a flavoring agent. It is used in food curry, pickles and other spices. Besides food application, the leaves have also been used for curing a number of ailments. All parts of the plant possess many major bioactive chemical constituents like cinnamaldehyde, trans-cinnamaldehyde, 3,4,5,7- tetrahydroxyflavone, 3,3,4,5,6- pentahydroflavone (non-glycoside compounds), kaempferol, eugenol, etc. These phytochemical compounds have many pharmacological activities such as anticancer, antidiabetic, antimicrobial, hepatoprotective, antidiarrheal and immunomodulatory. In the past time, it is also considered for medicinal use. Their medicinal use was also mentioned in the literature of ayurveda, yunani and other traditional systems of medicine. Due to aromatic fragrance, it is also utilized in the perfume industry. The major aim of this review is to give a brief knowledge about the plant Cinnamomum tamala based on their phytochemical constituents, ayurvedic view, folk view and pharmacological application.

Pharmacological Importance of Chromolaena odorata: a review

2021 ◽  
pp. 8-11
Author(s):  
Angitha Ajay ◽  
Rupesh Kumar M ◽  
Shamal Badhusha PA ◽  
Abhishek K ◽  
Sanjay K Gowda ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
West Africa ◽  
Pharmacological Properties ◽  
Conventional System ◽  
Chromolaena Odorata ◽  
Pharmacological Activities ◽  
Tropical Asia ◽  
Clinical Investigations ◽  
Medicinal Use ◽  
Medicinal Properties

Chromolaena odorata (Asteraceae) is commonly referred to as Siam Weed, a major medicinal plant found in tropical Asia, Australia, and West Africa. The medicinal use of Chromolaena odorata had been documented in the conventional system such as the Siddha, Unani, Ayurveda. The pharmacological properties of this plant are widely varying. A wide variety of attractive but limited compounds were extracted from this Chromolaena odorata and the pharmacological  activities   were   screened   out.   This   review   the   various   properties  of Chromolaena odorata and focus on its various medicinal properties. It is an attractive subject for further experimental and clinical investigations. This article will give an exhaustive summary and analysis of Chromolaena odorata pharmacological activities. The present article including the detailed exploration of pharmacological properties of C. odorata is an attempt to provide a direction for further research.

PHYTOCHEMICAL, PHARMACOLOGICAL SCREENING AND IMPORTANCE OF MARSDENIA TENACISSIMA: A REVIEW

INDIAN DRUGS ◽  
2021 ◽  
Vol 58 (4) ◽  
pp. 7-22
Author(s):  
Mayur Porwal ◽  
◽  
Arvind Kumar ◽  
Kamal K. Maheshwari ◽  
Najam A. Khan ◽  
...  
Keyword(s):  
Heart Disease ◽  
Skin Disease ◽  
Recent Literature ◽  
Biological Activities ◽  
Intermittent Fever ◽  
Pharmacological Activities ◽  
Phytochemical Constituents ◽  
Pharmacological Screening ◽  
Anti Hiv ◽  
Marsdenia Tenacissima

In conventional methods of medication, Marsdenia tenacissima (family: Apocynaceae) is used in the treatment of scurvy, urinary diseases, arthritis, heart disease, skin disease, pruritus, vomiting and intermittent fever. Estimation of biological activities confirmed that M. tenacissima plant shows antipyretic, antioxidant, anticancer and anti-HIV activities. This assessment presents the phytochemical constituents, traditional importance and pharmacological activities accounted for the plant in recent literature and it will be supportive to explore incisive information about M. tenacissima for the researchers.

Medicinal Inula Species: Phytochemistry, Biosynthesis, and Bioactivities

2021 ◽  
pp. 1-44
Author(s):  
Cheng-Peng Sun ◽  
Zi-Li Jia ◽  
Xiao-Kui Huo ◽  
Xiang-Ge Tian ◽  
Lei Feng ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Drug Development ◽  
Scientific Basis ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Traditional Medicines ◽  
The World ◽  
Phytochemical Constituents ◽  
New Drug Development ◽  
First Time

As a genus of the Asteraceae, Inula is widely distributed all over the world, and several of them are being used in traditional medicines. A number of metabolites were isolated from Inula species, and some of these have shown to possess ranges of pharmacological activities. The genus Inula contains abundant sesquiterpenoids, such as eudesmanes, xanthanes, and sesquiterpenoid dimers and trimers. In addition, other types of terpenoids, flavonoids, and lignins also exist in the genus Inula. Since 2010, more than 300 new secondary metabolites, including several known natural products that were isolated for the first time from the genus Inula. Most of them exhibited potential bioactivities in various diseases. The review aimed to summarize the advance of recent researches (2010–2020) on phytochemical constituents, biosynthesis, and pharmacological properties of the genus Inula for providing a scientific basis and supporting its application and exploitation for new drug development.

scholarly journals The Phytochemical Constituents and Pharmacological Activities of Annona atemoya: A Systematic Review

2020 ◽  
Vol 13 (10) ◽  
pp. 269
Author(s):  
Bassam S. M. Al Kazman ◽  
Joanna E. Harnett ◽  
Jane R. Hanrahan
Keyword(s):  
Systematic Review ◽  
South America ◽  
Annona Squamosa ◽  
Pharmacological Activities ◽  
Annona Cherimola ◽  
Pharmacological Studies ◽  
Custard Apple ◽  
Phytochemical Constituents ◽  
North And South America ◽  
North And South

Annona atemoya also known as the custard apple is a hybrid between two Annonaceae species: Cherimoya (Annona cherimola) and the sugar apple (Annona squamosa). It is widely cultivated in tropical and subtropical continents including north and south America, Asia, Africa and Australia. Despite becoming an increasingly important commercial fruit plant due to its’ creamy succulent flesh, compared to other Annonaceae species relatively few studies have investigated the phytochemistry and bioactivities of A. atemoya. Studies that evaluated A. atemoya extracts and its constituents were searched through the databases Scopus, Pubmed and Embase from inception to June 2020. Constituents of A. atemoya include alkaloids, flavonoids, terpenes and acetogenins. The results indicate that the constituents of A. atemoya possess cytotoxic, anti-angiogenic, hypolipidemic, antioxidant, anti-inflammatory and neuroprotective activities. However, many of these studies are currently limited in quality and further phytochemical and pharmacological studies are required.

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