Postnatal thyroid function in low birth weight infants: A cross-sectional assessment of free thyroxine and thyroid hormone binding globulin

1982 ◽  
Vol 139 (4) ◽  
pp. 244-246 ◽  
Author(s):  
T. Hirano ◽  
J. Singh ◽  
G. Srinivasan ◽  
R. Pildes

1985 ◽  
Vol 110 (1) ◽  
pp. 56-60 ◽  
Author(s):  
Takeki Hirano ◽  
Jaideep Singh ◽  
Gopal Srinivasan ◽  
Rosita Pildes

Abstract. Because the concentrations of serum free thyroxine (FT4) and thyroid hormone binding globulin (TBG) have not been fully evaluated in preterm infants at the immediate post-natal period, we studied the longitudinal changes of serum FT4 and TBG, along with thyroxine (T4) and thyroid stimulating hormone (TSH), at birth (cord blood), 2 days, 1 week and 2 weeks of age in 7 infants with birth body weight ≦ 1000 g, 7 infants with body weight 1001 to 1350 g, 11 infants with body weight 1351 to 2499 g, and 11 full-term infants. Free T4 concentrations were measured by Corning Medical radio-immunoassay (RIA) kit. The infants with extremely low birth weight (ELBW) (body weight ≦ 1000 g) showed precipitous declines of total T4 and, to a lesser extent, of FT4 concentrations at 1 and 2 weeks of age. These post-natal T4 and FT4 decreases in ELBW neonates have not previously been reported. The clinical significance of this finding remains, speculative, but it may be due to metabolic or nutritional problems related to extreme prematurity itself. This study suggests that measurement of FT4 is a useful adjunct to the assessment of ELBW infants with wery low T4 values, if done between 1 to 2 weeks af age, and could be used as a primary hypothyroid screening tool instead of T4 measurements, provided that an FT4 assay is developed that uses the elute of blood spotted on filter paper.



Neonatology ◽  
2001 ◽  
Vol 80 (3) ◽  
pp. 210-214 ◽  
Author(s):  
J. Dembinski ◽  
V. Arpe ◽  
M. Kroll ◽  
P. Bartmann ◽  
G. Hieronimi


2020 ◽  
Vol 8 (1) ◽  
pp. 58-60
Author(s):  
Mahaboob Basha Kallur ◽  
K. Muralidhar

Background: Retinopathy of prematurity (ROP) is a vaso-proliferative retinopathy which occurs mostly in premature babies. The pathological change in ROP is peripheral retinal neovascularisation which may regress completely or leave sequelae from mild myopia to bilateral total blindness. International classification of ROP helped in uniform documentation and staging of ROP. In India, the incidence of ROP is between 38 and 51.9 p.c among low-birth-weight infants. Aim & Objectives: To estimate the incidence of ROP among premature and / or low birth weight babies who were born and admitted to neonatal intensive care unit and attending neonatal follow-up clinic.Subjects and Methods:A hospital based, prospective analytical cross-sectional study was conducted in Department of Pediatrics at Shadan Institute of Medical Sciences, Teaching hospital and research center, Hyderabad, Telangana for a period of 6 months from 1st October 2018 to 31st March 2019. Prior to the study initiation, ethical clearance was obtained and written consent was taken from the parents of the respective babies. The study subjects included premature babies (less than or equal to 35 weeks of gestation) or low birth weight babies (less than or equal to 1500 grams). A predesigned, pre-tested, semi-structured proforma was used to collected the data. The data was collected, entered in Microsoft excel-2013 and analyzed using SPSS version-22 (trial). Data was presented in percentages, proportions and figures.Result:The ROP incidence in the study group was reported among 17.1 p.c of the study subjects.Conclusion:Low birth weight and prematurity are important risk factors for ROP.



Author(s):  
S.H. Elbeely ◽  
M.A. AlQurashi

BACKGROUND: Very low birth weight infants born prematurely are at greater risk for growth delays that lead to Ex-utero Growth Restriction (EUGR) during vulnerable periods of organ structural and functional development. There is considerable evidence that early growth failure has adverse effects on long term neurodevelopment in children which often persists into adulthood. METHODS: This is a single-center cross-sectional study on live newborn infants with birth weight ranges from 500 to 1500 grams (VLBW) and gestational age (GA) between 24–32 weeks who were admitted to NICU at KAMC-Jeddah over a 5 year period (2009–2013). This study aims to evaluate predischarge growth pattern of VLBW infants in terms of weight, head circumference (HC) and length and to identify important variables that have influenced such growth pattern. RESULTS: Of the 135 infants included in the final analysis, 68 (50.4%) were male and 67 (49.6%) were female and the mean gestational age was 28.83±2.064 weeks and the mean birth weight 1166.74±256 grams. Ninety-two infants (68%) had discharge weight at ≤10th percentile and forty four (32%) had their weight >10th percentile. HC was the lowest affected among the anthropometric measurements with 42% ≤10th percentile. In terms of linear growth, 62% had their length ≤10th percentile. Amongst infants born ≤750 grams, 71% and 70% had HC and height at ≤10th percentile respectively, at the time of discharge. BPD was significantly associated with EUGR (p = 0.026). CONCLUSIONS: This study demonstrates that almost 2/3rd of VLBW infants born at KAMC-Jeddah with birth weight ≤750 grams were discharged home with EUGR as demonstrated by their weight, length, and HC ≤10th percentile. BPD was found to be significantly associated with EUGR amongst post-natal factors influencing EUGR.



1983 ◽  
Vol 103 (5) ◽  
pp. 793-796 ◽  
Author(s):  
Masao Sakaguchi ◽  
Shigeyoshi Suzuki ◽  
Kanji Nagashima ◽  
Satoshi Shimano ◽  
Satoshi Uchida ◽  
...  


2020 ◽  
Author(s):  
Marie Kouya ◽  
Annie Carole Nga Motaze ◽  
Jeannette Epee Ngoué ◽  
Arsene Brunelle Sandie ◽  
Paul Olivier Koki Ndombo ◽  
...  

Abstract Introduction. Vaccination is very often delayed in premature and low birth weight infants. However, timely vaccination is even more important in the latter because of their increased susceptibility to infection.Objective. To assess immunization practice and factors associated with vaccine promptness and completeness in former preterm and low-birth-weight infants.Methods. We conducted a retrospective analytical cross-sectional study (January 2017 to February 2019). Main measurement : Promptness and completeness at each contact, Statistical analysis was performed using R software version 3.6.2, logistic regression was used to estimate the Odds Ratio (OR) and their 95% Confidence Interval (CI).Results. We recruited 310 children aged 12 to 36 months born before 37 weeks with low birth weight, 163 (52.6%) of whom were female. Two hundred and fifty-three had received the vaccines at the indicated age, with promptness rate of 81.6%, and 97.7% had completed routine immunization at 9 months. The mean age at vaccination initiation was 6 days ±11 and the mean weight at vaccination initiation was 2233g ±494. High prematurity and very low birth weight were associated with a high rate of vaccine delay: 61.5% [OR: 15.56; (CI: 3.22-118.52; p=0.002)] and 66.7% [OR: 19.19; (CI: 4.67-92.52; p<0.001)] respectively. Distance > 5 km with HEC [OR: 3.48; (CI: 1.68-7.47; p=0.001)] was associated with poor vaccination. Women in common-law unions had the lowest vaccine readiness rate (60.6%), (OR: 3.36; CI: 1.006-10.70; p=0.038). The frequency of occurrence of post immunization adverse events was 24.5%, with fever type in 94.7%.Conclusion. Nearly all premature and/or low-birth-weight children hospitalized at Essos Hospital Center had completed routine immunization at 9 months, and the majority had received the vaccines in a timely manner. Similar study is needed in rural area.



2018 ◽  
Vol 12 (1) ◽  
pp. 61
Author(s):  
U. Evi Nasla Nasla

Abstract: The efforts of decreasing the infant mortality is focused on the causes of infant’s death. One of them  is the lowest Birth Weight that can be prevented through a quality and comprehensive antenatal care. The factors that affect the occurrence of low birth weight (LBW) in Singkawang city is age, parity, range of pregnancy, arm circumference, antenatal care, anemia history, newborn weight. The objective study was to determine the factors that affect the occurrence of LBW in Singkawang in 2015. This research employed analytical survey research design with retrospectively approach with cross sectional design. The sample used is the case of newborn with LBW as many as 105 with a ratio of 1: 1 with a total sample of 210 babies. The sample was random sampling. The data analysis used Chi Square and logistic regression test. Chi Square test results showed that there was a significant relationship between age, arm circumference, antenatal care of anemia (p = 0.005, p = 0.013, p = 0.020, p = 0.003) with the incidence of LBW. And there was no significant correlation between parity and range of pregnancy (p = 0.805, p = 0.766). This research is expected to be the basis of evaluating the occurrence of LBW thus it can be detected earlier.Keywords: Age; Parity; Antenatal Care; Arm Circumference; Anemia history; Lowest Birt Weight.



2014 ◽  
Vol 1 (2) ◽  
pp. 91
Author(s):  
Fatimah Sari ◽  
Evy Ernawati ◽  
Indartik Indartik

Background: One of the most common causes of death of neonates are low birth weight (LBW) either at term or preterm (premature). As a result of the premature births, children born will experience a variety of health problems due to lack of maturation of the fetus at birth which resulted in many organs of the body that have not been able to work perfectly. factors that can lead to preterm labor (preterm) or low birth weight infants is mother's first factor is less than 20 years of age or over 35 years . Method: This study aims to determine the relationship between maternal age with the incidence of preterm labor. Objective: This research is the type of observational analytic study with cross sectional approach. The sampling technique using saturated sample and the number of samples in this study were 75 respondents. Result: The results showed no association with maternal age on the incidence of preterm labor Puskesmas Kaliangkrik Magelang Regency in 2012 with a p value of 0.000 (0.000 < 0.05) and the relationship is strong enough that the value of the Contingency Coefficient .431. Conclusion: There is a relationship with the mother's age incidence of preterm labor.



2021 ◽  
Vol 1 ◽  
pp. 554-561
Author(s):  
Hesti Rizqiana ◽  
Benny Afief Sulistyanto

AbstractBabies with low brith weight (LBW) require special care to prevent neonatal death due to low birth weight. To identify the description of the implementation of Kangaroo Mother Care (KMC) care in low birth weight infants. This research method used Literature Review. Research articles from several databases, namely PubMed and Portal garuda, were identified using the keywords "Kangaroo Mother Care" AND "Low Brith Weight" AND "Practice".These articles were published in 2015-2021. Research articles that met the inclusion and exclusion criteria were reviewed using the JBI Cross Sectional Study instrument. There are five articles analyzed in this study. The results of the study showed the implementation of Kangaroo Mother Care (KMC) in LBW infants. The average time of KMC implementation duration 65 minutes. Most of the respondent carried out KMC in the hospital after giving birth with the correct SOP according to the hospital procedures. It can be concluded that the implementation of Kangaroo Mother Care (KMC) can increase body weight in LBW babies, normal body temperature, and increase breastfeeding or nutrition.Keywords: LBW Babies; Kangaroo Mother Care; Practice AbstrakBayi dengan berat badan lahir rendah (BBLR) memerlukan perawatan yang khusus untuk mencegah terjadinya kematian neonatal. Kangaroo Mother Care (KMC) adalah salah satu cara yang mudah dan efektif untuk mencegah terjadinya kematian neonatal akibat BBLR. Untuk mengidentifikasi gambaran pelaksanaan perawatan Kangaro Mother Care (KMC) pada bayi berat badan lahir rendah. Metode penelitian ini menggunakan Literature Review. Artikel penelitian dari beberapa database yaitu PubMed dan Portal garuda di identifikasi dengan menggunakan kata kunci “Kangaroo Mother Care” AND “Low Brith Weight” AND “Practice” yang di batesi dari tahun 2015-2021. Artikel penelitian yang memenuhi kriteria inklusi dan ekslusi di telaah dengan menggunakan instrument JBI Cross Sectional studi. Terdapat lima artikel yang dianalis pada penelitian ini. Hasil dari penelitian menunjukan pelaksanaan Kangaroo Mother Care (KMC) pada bayi BBLR yaitu terdapat durasi waktu pelaksanaan KMC yaitu rata-rata 65menit, mayoritas ibu yang melaksanakan, dilakukan di Rumah Sakit setelah bayi lahir dan dengan cara SOP KMC yang benar sesuai prosedur RS masing-masing. Dapat di simpulkan bahwa pelaksanaan Kangaroo Mother Care (KMC) yang dilakukan dapat meningkatkan berat badan pada bayi BBLR, suhu tubuh normal dan meningkatkan pemberian ASI atau nutrisi.Kata kunci: Bayi BBLR; Perawatan Metode Kanguru; Praktik



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