scholarly journals “Trooping the color”: restoring the original donor skin color by addition of melanocytes to bioengineered skin analogs

2012 ◽  
Vol 29 (3) ◽  
pp. 239-247 ◽  
Author(s):  
Sophie Böttcher-Haberzeth ◽  
Agnieszka S. Klar ◽  
Thomas Biedermann ◽  
Clemens Schiestl ◽  
Claudia Meuli-Simmen ◽  
...  
PeerJ ◽  
2018 ◽  
Vol 6 ◽  
pp. e4815 ◽  
Author(s):  
Wen-Shyan Huang ◽  
Yi-Wen Wang ◽  
Kun-Che Hung ◽  
Pai-Shan Hsieh ◽  
Keng-Yen Fu ◽  
...  

Background To treat skin color disorders, such as vitiligo or burns, melanocytes are transplanted for tissue regeneration. However, melanocyte distribution in the human body varies with age and location, making it difficult to select the optimal donor skin to achieve a desired color match. Determining the correlations with the desired skin color measurement based on CIELAB color, epidermal melanocyte numbers, and melanin content of individual melanocytes is critical for clinical application. Method Fifteen foreskin samples from Asian young adults were analyzed for skin color, melanocyte ratio (melanocyte proportion in the epidermis), and melanin concentration. Furthermore, an equation was developed based on CIELAB color with melanocyte ratio, melanin concentration, and the product of melanocyte ratio and melanin concentration. The equation was validated by seeding different ratios of keratinocytes and melanocytes in tissue-engineered skin substitutes, and the degree of fitness in expected skin color was confirmed. Results Linear regression analysis revealed a significant strong negative correlation (r =  − 0.847, R2 = 0.717) between CIELAB L* value and the product of the epidermal melanocyte ratio and cell-based melanin concentration. Furthermore, the results showed that an optimal skin color match was achieved by the formula. Discussion We found that L* value was correlated with the value obtained from multiplying the epidermal melanocyte ratio (R) and melanin content (M) and that this correlation was more significant than either L* vs M or L* vs R. This suggests that more accurate prediction of skin color can be achieved by considering both R and M. Therefore, precise skin color match in treating vitiligo or burn patients would be potentially achievable based on extensive collection of skin data from people of Asian descent.


2020 ◽  
Vol 3 ◽  
pp. 81-84
Author(s):  
Karen Chan

For me, rhythm means having consistency. The piece highlights my own experience with the disruption of my daily rhythm due to COVID-19. The first half shows my routine and interactions prior to COVID-19 while the second half shows my experiences in the present day. Prior to the virus, I had a day to day routine that was filled with noise. Everyday moved quickly and I established a daily rhythm. However, when COVID-19 spread, it changed everything. I felt like I didn’t have a routine anymore because I wasn’t allowed to go anywhere. Time was moving much slower and worst of all, xenophobia was growing at a significant rate. As a Chinese Canadian, this was the first time I truly felt the weight of the color of my skin. COVID-19 changed the way that I consistently assumed that the color of my skin wasn’t something that strangers would significantly care about. However, as I got on a bus, I unintentionally scared a woman simply because of my skin color. From that point, I knew that xenophobia would affect the way people perceived me everyday. The woman was scared of the virus— which in turn was scared of me—and I was scared that she would thwart her anger towards me because I am Chinese. If looks could kill, then the woman and I ironically both feared each other. Now, due to COVID-19, I am adapting to a new routine. A routine where the color of skin rings louder than any other sound.


2018 ◽  
Vol 9 (06) ◽  
pp. 20251-20256
Author(s):  
Mudassir Khan ◽  
Shahrukh Khan ◽  
Shohra Haider ◽  
Fazal Jalil ◽  
Muhsin Jamal ◽  
...  

Background: Prevalence of Hepatitis C viral infection and its major risk factors has been found out in population of Batkhela, Khyber Pakhtunkhwa, Pakistan by taking number of volunteers from the interested area. HCV prevalence has not been researched in recent time here in this area, so that’s why we contributed. Materials and Methods: Ab rapid test cassette serum/plasma (USA) kit has been used for the mentioned purpose following by ELISA and finally PCR to find out active infection of virus. ICT positive individuals were reconfirmed by ELISA and then ELISA positive samples were carefully investigated by RT-PCR for Hepatitis C Virus. Results: The study population was of 770 volunteers belonging to the mentioned area of research, 453 males and 317 females. The overall prevalence was found to be 5.32% of HCV in Batkhela. This prevalence ratio was 3.12% in males and 2.20 % in females. 3rd generation ELISA was used to refine ICT positive samples which showed that 37 of the ICT positive samples had antibodies detected by ELISA. To find out active HCV infection, ELISA positive samples were refined by real time PCR which showed 2.98% of prevalence of active HCV infection in Batkhela based on HCV RNA in their blood. Principle Conclusion: Overall prevalence was found 5.32%, contaminated reused syringes and blades at Barbour’s shop, blood transfusion, surgical operations and unhygienic food in stalls etc were found significant risk factors for acquiring HCV infection. Body weakness and pale yellow skin color was common symptom in HCV positive volunteers. Safe sexual activities, blood screening before donation and sterilizing surgical equipment’s can protect us from Hepatitis C Virus.


1993 ◽  
Vol 55 (3) ◽  
pp. 468-475 ◽  
Author(s):  
Hirotsugu TAKIWAKI ◽  
Shiro SHIRAI ◽  
Masahiro UTSUNOMIYA ◽  
Yasumori WATANABE ◽  
Yoshiyuki KANNO

Author(s):  
Yuchun Yan ◽  
Hayan Choi ◽  
Hyeon-Jeong Suk

It is difficult to describe facial skin color through a solid color as it varies from region to region. In this article, the authors utilized image analysis to identify the facial color representative region. A total of 1052 female images from Humanae project were selected as a solid color was generated for each image as their representative skin colors by the photographer. Using the open CV-based libraries, such as EOS of Surrey Face Models and DeepFace, 3448 facial landmarks together with gender and race information were detected. For an illustrative and intuitive analysis, they then re-defined 27 visually important sub-regions to cluster the landmarks. The 27 sub-region colors for each image were finally derived and recorded in L ∗ , a ∗ , and b ∗ . By estimating the color difference among representative color and 27 sub-regions, we discovered that sub-regions of below lips (low Labial) and central cheeks (upper Buccal) were the most representative regions across four major ethnicity groups. In future study, the methodology is expected to be applied for more image sources.


Author(s):  
Trương Thị Hồng Hải ◽  
Nguyễn Thị Diệu Thể ◽  
Phan Thu Thảo

In order to establish the pure line of sponge gourd containing aroma feature, we selected the desirable inbred lines by using a self-pollinating method. The present study was investigated to estimate the morphological traits and fruit quality of 6 sponge gourd inbred lines which generated at 4th generation of an aroma Luffa accession B29 under plastic house conditions. The experiment was conducted in a randomized complete block design (RCBD) with three replications, from May to November in 2016. Five plants per replication were examined. The results indicated that all inbred lines could grow well under plastic house conditions. The inbred lines had the same stem and leaf traits; whereas fruit shape, skin color and fruit veins color were observed differently among inbred lines. The aromatic trait was retained in all inbred lines either before or after cooking. The high yield was found in lines BC1 and BC2 by 10.1 tons/ha and 10.7 tons/ha, respectively. These inbred lines should be examined in open field condition to confirm the presence of aromatic trait and yield potential before completion of the procedures for recognition of new Luffa varieties.  


2019 ◽  
Vol 15 (2) ◽  
pp. 101-105
Author(s):  
Makful Makful ◽  
Kuswandi Kuswandi ◽  
Sahlan Sahlan ◽  
Mega Andini

Hybrid breeding of watermelon has led to the formation of high-yielding varieties. The objectives of the research were to determine the performance of hybrid watermelon of the Indonesian Tropical Fruit Research Institute (ITFRI) collection and to evaluate the superiority of each hybrid. The research has been conducted at Sumani Experimental Garden, ITFRI, Solok, West Sumatera, from April to July 2016. The material used consisted of 19 cross combinations. The data from this descriptive study were presented in the form of averages and pictures. The results showed that the hybrids that were tested showed diversity in size, fruit skin color, flesh color, skin thickness and fruit sweetness. Hybrids with three excellent characters, i.e. medium fruit weight, high total soluble solids (TSS) value, and moderate rind thickness, were not yet obtained. Hybrids that had the superiority in term of sweet taste and shelf life were BT1 × SGP, BT4 × BT4P, BT5 × BT4, BT6 × SGP and SGP × BT6. Keywords: hybrid, performance, total soluble solids, watermelon   ABSTRAK Pemuliaan hibrida pada semangka mengarah kepada pembentukan varietas berdaya hasil tinggi. Penelitian bertujuan untuk mengetahui keragaan hibrida semangka koleksi Balitbu Tropika dan untuk mengevaluasi keunggulan masing-masing hibrida Penelitian dilaksanakan di Kebun Percobaan Sumani, Balitbu Tropika, Solok, Sumatera Barat, dari bulan April sampai dengan Juli 2016. Materi yang digunakan terdiri dari 19 kombinasi persilangan. Data hasil penelitian deskriptif ini ditampilkan dalam bentuk rataan dan gambar. Hasil penelitian menunjukkan bahwa hibrida yang diuji memiliki keragaman dalam ukuran, warna kulit buah, warna daging buah, ketebalan kulit buah dan kemanisan. Belum ditemukan hibrida yang memiliki tiga karakter unggul, yang terdiri dari bobot buah sedang, total padatan terlarut (total soluble solid) tinggi, dan kulit buah agak tebal. Hibrida yang memiliki keunggulan berupa rasa manis dan tahan simpan adalah BT1 × SGP, BT4 × BT4P, BT5 × BT4, BT6 × SGP dan SGP × BT6. Kata kunci: hibrida, keragaan, semangka, total padatan terlarut


HortScience ◽  
1998 ◽  
Vol 33 (3) ◽  
pp. 520d-520
Author(s):  
Oswaldo Valor ◽  
Juan E Manzano

Mango fruits `Criollo de Bocado' harvested at the mature-green stage were treated with a hydrothermic treatment of 55 °C for 3 min and stored for 20 days to temperatures of 10 ± 2, 15 ± 2, and 28 ± 2 °C. A randomized design 2 × 3 × 4 with three replications was used. Physical parameters such as color (L*, a*, b*), firmnness, and fresh weight loss were studied. Results reported that mango fruits stored at 10.2 and 15.2 °C showed the highest firmness values. Skin color changed very fast during the first storage days, while pulp color required more time to achieve mature ripe color. Fresh weight loss tended to increase with storage time and with high storage temperature. The lowest storage temperture retarded softening in mango fruits and firmnness reached the highest values.


Sign in / Sign up

Export Citation Format

Share Document