scholarly journals Efficiency in PrEP Delivery: Estimating the Annual Costs of Oral PrEP in Zimbabwe

2021 ◽  
Author(s):  
Collin Mangenah ◽  
Definate Nhamo ◽  
Stephano Gudukeya ◽  
Emily Gwavava ◽  
Chiedza Gavi ◽  
...  

AbstractAlthough oral PrEP is highly effective at preventing HIV acquisition, optimizing continuation among beneficiaries is challenging in many settings. We estimated the costs of delivering oral PrEP to populations at risk of HIV in seven clinics in Zimbabwe. Full annual economic costs of oral PrEP initiations and continuation visits were estimated from the providers’ perspective for a six-clinic NGO network and one government SGBV clinic in Zimbabwe (January–December 2018). Disaggregating costs of full initiation and incremental follow-up visits enabled modeling of the impact of duration of continuation on the cost per person-year ($pPY) on PrEP. 4677 people initiated oral PrEP, averaging 2.7 follow-up visits per person. Average cost per person initiated was $238 ($183–$302 across the NGO clinics; $86 in the government facility). The full cost per initiation visit, including central and direct costs, was $178, and the incremental cost per follow-up visit, capturing only additional resources used directly in the follow up visits, was $22. The average duration of continuation was 3.0 months, generating an average $pPY of $943, ranging from $839 among adolescent girls and young women to $1219 in men. Oral PrEP delivery costs varied substantially by scale of initiations and by duration of continuation and type of clinic. Extending the average oral PrEP continuation from 2.7 to 5 visits (about 6 months) would greatly improve service efficiency, cutting the $pPY by more than half.

Author(s):  
Garth M. Bray ◽  
Deanna L. Huggett

AbstractThe National Population Health Study of Neurological Conditions, a partnership between Neurological Health Charities Canada and the Government of Canada, was the largest study of neurological diseases, disorders, and injuries ever conducted in Canada. Undertaken between 2009 and 2013, the expansive program of research addressed the epidemiology, impacts, health services, and risk factors of 18 neurological conditions and estimated the health outcomes and costs of these conditions in Canada through 2031. This review summarizes highlights from the component projects of the study as presented in the synthesis report, Mapping Connections: An Understanding of Neurological Conditions in Canada. The key findings included new prevalence and incidence estimates, documentation of the diverse and often debilitating effects of neurological conditions, and identification of the utilization, economic costs, and current limitations of related health services. The study findings will support health charities, governments, and other stakeholders to reduce the impact of neurological conditions in Canada.


Author(s):  
Shahabuddin Mohammed Ahmed Abdullah

The traffic accidents in the high ways and towns are still increasing, their effect on the community development clearly seen. The control of this problem is highly significant. The analysis of the data and the information about the traffic accidents, their direct, indirect, a variables and continues cost represented in curing the injured, paying the Diya, the cost of the medical operations on behalf of the government and the relatives of the injured dealt with through the accounting view. This paper aimed at measuring the effect of traffic accidents in terms of money, to be use for the development of Accer province – South of the kingdom of Saudi Arabia. The overall cost of the traffic accidents in 2013 is 23 pillions Riyal. The percentage of the injured is 30% per family. The cost account of traffic accidents in Accer province is 1. 6 pillions Riyal. These sums of money could have been use for the development of the province. The paper recommends The direct, indirect, a variables and continues costs of the traffic accidents should give a due consideration The traffic administration should give a due consideration as well, to be minimizing the number of the traffic accidents. There should be decisive practical measures to stop these accidents.


2011 ◽  
Vol 31 (6) ◽  
pp. 853-865 ◽  
Author(s):  
Claire McKenna ◽  
Karl Claxton

Methods to estimate the cost-effectiveness of technologies are well developed with increasing experience of their application to inform adoption decisions in a timely way. However, the experience of using similarly explicit methods to inform the associated research decisions is less well developed despite appropriate methods being available with an increasing number of applications in health. The authors demonstrate that evaluation of both adoption and research decisions is feasible within typical time and resource constraints relevant to policy decisions, even in situations in which data are sparse and formal elicitation is required. In addition to demonstrating the application of expected value of sample information (EVSI) in these circumstances, the authors examine and carefully distinguish the impact that the research decision is expected to have on patients while enrolled in the trial, those not enrolled, and once the trial reports. In doing so, the authors are able to account for the range of opportunity cost associated with research and evaluate a number of research designs including length of follow-up and sample size. The authors also explore the implications for research design of conducting research while the technology is approved for widespread use and whether approval should be withheld until research reports. In doing so, the authors highlight the impact of irrecoverable opportunity costs when the initial costs of a technology are compensated only by later gains in health outcome.


2020 ◽  
Vol 24 (9) ◽  
pp. 902-909
Author(s):  
D. Collins ◽  
H. Lam ◽  
H. Firdaus ◽  
J. Antipolo ◽  
P. Mangao

SETTING: The Philippines has a population of over 90 million people and is one of the 22 highest TB burden countries in the world.OBJECTIVE: To understand the economic cost of non-adherence to TB medicines due to loss to follow up and stock-outs in the Philippines.DESIGN: Data were collected on the economic costs of non-adherence to TB medicines and a model was developed to show those costs under different scenarios.RESULTS: The model showed that as many as 1958 and 233 persons are likely to have died as a result of DS-TB and MDR-TB loss to follow up, respectively, and 588 persons are likely to have died as a result of TB medicine stock outs. The related economic impact in each case is likely have been to be as much as US$72.2 million, US$13.4 million and US$21.0 million, respectively.CONCLUSION: The economic costs of non-adherence to TB medicines due to loss to follow-up and stock-outs represent a significant economic burden for the country and it is likely that the cost of addressing these problems would be much less than this burden and, therefore, a wise investment.


2014 ◽  
Vol 25 (4) ◽  
pp. 612-618 ◽  
Author(s):  
Amiya Kumar Bagchi

The need for a new economy is great and the obstacles are many: growing inequalities within and between nations and regions, new complicity between corporations and non-democratic political regimes and failure of workers worldwide to make common cause. There are alternative models, indicating that a more egalitarian approach does not necessarily reduce living standards. Environmental degradation cannot be addressed by a technological fix: the threat to our long-term survival is pre-figured in the impact of climate change and corporate rapacity on the land and sea resources of the indigenous minorities who live as humanity has lived for most of its existence. A 10-point plan for a follow-up to the United Nations’ Millennium Development Goals is suggested, but it will work only if solidarity networks can be built across divides of ascribed race, religion and nominal income levels, to express the will of the people in place of the government representatives who are prepared to gamble the future of humanity for corporate profit and power.


2021 ◽  
Author(s):  
Stacey Orangi ◽  
Angela Kairu ◽  
Anthony Ngatia ◽  
John Ojal ◽  
Edwine Barasa

Background: Vaccines are considered the path out of the COVID-19 pandemic. The government of Kenya is implementing a phased strategy to vaccinate the Kenyan population, initially targeting populations at high risk of severe disease and infection. We estimated the financial and economic unit costs of procuring and delivering the COVID-19 vaccine in Kenya across various vaccination strategies. Methods: We used an activity-based costing approach to estimate the incremental costs of COVID-19 vaccine delivery, from a health systems perspective. Document reviews and key informant interviews (n=12) with stakeholders involved in the vaccine delivery and administration at a national level and in two counties were done to inform the activities, assumptions and the resources required. Unit prices were derived from document reviews or from market prices. Both financial and economic vaccine procurement costs per person vaccinated with two doses, and the vaccine delivery costs per person vaccinated with two doses were estimated and reported in 2021 USD. Results: The financial costs of vaccine procurement per person vaccinated with two doses ranged from $2.89 to $13.09 in the 30% and 100% coverage levels respectively. The economic costs of vaccine procurement per person vaccinated with two doses was $17.34 across all strategies. With regard to unit vaccine delivery costs per person vaccinated with two doses, the financial costs ranged from $4.28 to $3.29 in the 30% and 100% coverage strategies: While the economic delivery costs were two to three times higher than the financial costs. The total procurement and delivery costs per person vaccinated with 2-doses ranged from $7.34 to $16.47 for the financial costs and $29.7 to $24.68 for the economic costs for the 30% and 100% coverage respectively. With the exception of procurement costs, the main cost driver of financial and economic delivery costs was supply chain costs (47-59%) and advocacy, communication and social mobilization (29-35%) respectively. Conclusion: This analysis presents cost estimates that can be used to inform local policy and may further inform parameters used in cost-effectiveness models. The results could potentially be adapted and adjusted to country-specific assumptions to enhance applicability in similar low-and middle-income settings.


2012 ◽  
Vol 37 (1-2) ◽  
Author(s):  
Marketa Rulikova

This paper considers the impact of the most recent global economic crisis on immigration in theCzechRepublic. Developments during this economically troubled period suggest that the “immigration-inexperienced”CzechRepublic, which has attracted significant numbers of people seeking economic opportunities in the past decade for the first time, has repeated historical mistakes made by Western European countries during the 1970s oil crisis. Initially, promising economic growth at the beginning of the decade allowed the Czech government to ignore issues of immigration, including controlling inflow and immigrants’ integration into the majority of society. The sudden reality of jobs disappearing in late 2008, irrespective of the fact that many employers in the economic sectors are dependent on foreign guest workers, caught the country unprepared. In an effort to level the unemployment rate and dampen societal unrest, theCzechRepublicoffered financial assistance to immigrants who opted to depart voluntarily, but officials overestimated the willingness of foreign labourers to return home, even if gainful work vanished.This paper is based on research conducted among participants of the government-assisted Voluntary Return Programme and a follow-up ethnographic study in the Vietnamese, Ukrainian and Mongolian communities in Prague. It can be shown that most immigrants decided to stay despite extreme declines in their living conditions. While the motivations of immigrants to leave or stay are multifaceted, this paper offers an alternative to the “pull-push” model that takes into consideration economic as well as cultural factors, which both impede and inhibit migrants from returning “home”.


2020 ◽  
Vol 6 (2) ◽  
pp. 401-418
Author(s):  
Tehmeena Iqbal ◽  
Ihtsham Ul Haq Padda ◽  
Shujaat Farooq

This study has explored the welfare impact of Benazir Income Support Program’s (BISP) unconditional cash transfers on women empowerment. The program was initiated in 2011 by the government of Pakistan. The impact has been computed by using two follow up rounds i.e, 2011 & 2016 where baseline was carried out in 2011 and follow-up round was carried out in 2016. Regression Discontinuity Design approach was used to measure casual effects of the BISP cash transfers on women empowerment by selecting target and control groups based on proxy means test. The overtime impact have been estimated by employing Difference in Difference (DiD) model on panel households from 2011-2016. The study observed that BISP led to improve socio-economic wellbeing of the beneficiary women. It has brought improvement in women mobility and women participation in voting. The important contribution is an improvement in the aspect of socio-economic and political empowerment and women mobility across time and overtime. This showed continues support for longer period brought desired results.


1970 ◽  
Vol 1 (2) ◽  
pp. 189-202
Author(s):  
Ernawati Ernawati

Consumers have the freedom to determine the type and quality of the goods/services in accordance with their needs. Food safety, quality problems and the impact of irregularities, as well as the strengths, weaknesses, opportunities and threats in the development of food industry quality system is a shared responsibility as the consumer protection efforts. The method in this research using qualitative methods. The research results showed that consumer protection conducted by government agencies and other institutions in the following way i.e. perform monitoring of food products by giving the number of the PIRT against businessmen who are qualified and have previously received counseling about the food products that may be released, as well as to provide warning and withdrawal of products that contain a positive dye textiles.  The efforts made by the North Buton Regency POM Halls namely collaborates with government agencies and Institutions Consumers North Buton Regency to do surveillance, sampling and testing, guidance products. Trade a proven violation reported to the District Health Office of North Buton for follow up. Restricting factors for the Government and Consumers North Buton Regency in coping with a circulation of foods that contain colouring substances in textiles, namely budget constraints to organise activities agenda so that there are no activities were carried out, bureaucratic system which is still so convoluted follow-up to businessmen.


2018 ◽  
Vol 7 (3.21) ◽  
pp. 200
Author(s):  
Ismiriai Nasip ◽  
Eka Sudarmaji

The IFRS-16 will shortly be implemented worldwide, where the operating lease is effectively removed, and all operational leases are qualified as debt. The operational lease is a major source and is important for off-balance sheet financing in Indonesia. Therefore, the implementation of IFRS-16 will probably hurt Indonesian business. The contract and/or service level agreements on the retrofits for the energy efficiency product can relieve the business owner from cash flow and new debts. This study established a framework for a critical comparative study; compare and assess the possibility of the retrofit financial practices under the current taxes regime, and the possibility upon IFRS-16 implementation to better understand the favorable measures for retrofit practitioners and future customers to handle the disputes. Triangulate the findings of comparative study and questionnaire survey to develop recommendation for the future researchers, practitioners and the government. The result indicates that the benefits of the retrofits financing implementation beat the cost and complexity posed by the enactment of new IFRS standards. Thus, the impact of the IFRS-16 and taxation are being considered as a part of business constraints that should be addressed together and able to manage the disputes over misperception on retrofits aspects with taxes officers.  


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