scholarly journals Climate events and the role of adaptive capacity for (im-)mobility

2022 ◽  
Author(s):  
Vally Koubi ◽  
Lena Schaffer ◽  
Gabriele Spilker ◽  
Tobias Böhmelt
Keyword(s):  
Adaptive Capacity ◽  
Sudden Onset ◽  
Economic Resources ◽  
Gradual Onset ◽  
And Migration ◽  
Climate Events ◽  
The Relationship ◽  
Representative Samples ◽  
Country Specific

AbstractThe study examines the relationship between sudden- and gradual-onset climate events and migration, hypothesizing that this relationship is mediated by the adaptive capacity of affected individuals. We use survey data from regions of Cambodia, Nicaragua, Peru, Uganda, and Vietnam that were affected by both types of events with representative samples of non-migrant residents and referral samples of migrants. Although some patterns are country-specific, the general findings indicate that less educated and lower-income people are less likely to migrate after exposure to sudden-onset climate events compared to their counterparts with higher levels of education and economic resources. These results caution against sweeping predictions that future climate-related events will be accompanied by widespread migration.

Credit constraints and Rural Migration: Evidence from Six Villages in Uttar Pradesh

2018 ◽  
Vol 15 (3) ◽  
pp. 389-398
Author(s):  
Ruchi Singh
Keyword(s):  
Credit Constraints ◽  
Uttar Pradesh ◽  
Binary Logistic Regression ◽  
Binary Logistic Regression Model ◽  
Male Migration ◽  
Rural Economies ◽  
And Migration ◽  
The Relationship ◽  
The Empirical Analysis

Rural economies in developing countries are often characterized by credit constraints. Although few attempts have been made to understand the trends and patterns of male out-migration from Uttar Pradesh (UP), there is dearth of literature on the linkage between credit accessibility and male migration in rural Uttar Pradesh. The present study tries to fill this gap. The objective of this study is to assess the role of credit accessibility in determining rural male migration. A primary survey of 370 households was conducted in six villages of Jaunpur district in Uttar Pradesh. Simple statistical tools and a binary logistic regression model were used for analyzing the data. The result of the empirical analysis shows that various sources of credit and accessibility to them play a very important role in male migration in rural Uttar Pradesh. The study also found that the relationship between credit constraints and migration varies across various social groups in UP.

The role of sustainability in the relationship between migration and smart cities: a bibliometric review

2020 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Ali Mohamad Mouazen ◽  
Ana Beatriz Hernández-Lara
Keyword(s):  
State Of The Art ◽  
Smart Cities ◽  
Developed Countries ◽  
The State ◽  
Social Dimension ◽  
Content Type ◽  
Bibliometric Review ◽  
And Migration ◽  
The Relationship

Purpose Smart cities attract efficient and profitable economic activities, contribute to the societal welfare of their citizens and foster the efficient use and conservation of natural resources. Developing smart cities has become a priority for many developed countries, but as they are preferred destinations for migrants, this raises sustainability issues. They attract people who are seeking a better quality of life, smart services and solutions, a better environment and business activities. The purpose of this paper is to review the state of the art on the relationship between smart cities and migration, with a view to determining sustainability. Design/methodology/approach A bibliometric review and text mining analyses were conducted on publications between 2000 and 2019. Findings The results determined the main parameters of this research topic in terms of its growth, top journals and articles. The role of sustainability in the relationship between smart cities and migration is also identified, highlighting the special interest of its social dimension. Originality/value A bibliometric approach has not been used previously to investigate the link between smart cities and migration. However, given the current relevance of both phenomena, their emergence and growth, this approach is appropriate in determining the state of the art and its main descriptors, with special emphasis on the sustainability implications.

Human pregnancy: the role of chemokine networks at the fetal–maternal interface

2004 ◽  
Vol 6 (11) ◽  
pp. 1-14 ◽  
Author(s):  
Kristy Red-Horse ◽  
Penelope M. Drake ◽  
Susan J. Fisher
Keyword(s):  
Chemokine Receptors ◽  
Immune Cell ◽  
Leukocyte Trafficking ◽  
Placental Development ◽  
Effector Cells ◽  
Chemokine Expression ◽  
Multifunctional Molecules ◽  
And Migration ◽  
The Relationship

Chemokines are multifunctional molecules initially described as having a role in leukocyte trafficking and later found to participate in developmental processes such as differentiation and directed migration. Similar events occur in pregnancy during development of the fetal–maternal interface, where there is extensive leukocyte trafficking and tissue morphogenesis, and this is accompanied by abundant chemokine expression. The relationship between chemokines, leukocytes and placental development is beginning to be delineated. During pregnancy a specialised population of maternal leukocytes infiltrates the implantation site. These leukocytes are thought to sustain the delicate balance between protecting the developing embryo/fetus and tolerating its hemiallogeneic tissues. A network of chemokine expression by both fetal and maternal components in the pregnant uterus functions in establishing this leukocyte population. Intriguingly, experiments investigating immune cell recruitment revealed the additional possibility that chemokines influence aspects of placental development. Specifically, cytotrophoblasts, the effector cells of the placenta, express chemokine receptors that can bind ligands found at key locations, implicating chemokines as regulators of cytotrophoblast differentiation and migration. Thus, as in other systems, at the fetal–maternal interface chemokines might regulate multiple functions.

Surface Energy-mediated Protein and Osteoblast Responses on Nanostructured Stiff Surfaces

2012 ◽  
Vol 1486 ◽  
Author(s):  
Lei Yang ◽  
Maswazi Sihlabela ◽  
Brian W. Sheldon ◽  
Thomas J. Webster
Keyword(s):  
Surface Energy ◽  
Chemical Vapor ◽  
Cellular Responses ◽  
Enzyme Linked Immunosorbent Assay ◽  
Plasma Chemical ◽  
Nanostructured Surfaces ◽  
Plasma Chemical Vapor Deposition ◽  
And Migration ◽  
The Relationship

ABSTRACTNanostructured surfaces have demonstrated extraordinary capacity to influence protein adsorption and cellular responses, although the mechanisms behind such capacity are still not clear to date. In the present study, the role of surface energy associated with nanostructured stiff surfaces in modulating fibronectin and consequently osteoblast (OB, bone forming cells) responses was investigated. Nanocrystalline diamond (NCD) and submicron crystalline diamond (SMCD) films with controllable surface energy were prepared by microwave-enhanced plasma chemical vapor deposition (MPCVD) techniques. Fibronectin adsorption on the diamond films with varied surface energy values was measured via the enzyme-linked immunosorbent assay (ELISA) and the relationship between the surface energy and fibronectin adsorption was studied. OB aggregates (each containing 30∼50 cells) on the NCD with varied surface energy values were also studied. The results indicated that fibronectin adsorption on nanostructured surfaces was closely related to both surface energy and material microstructures, and osteoblast spreading and migration on stiff nanosurfaces are surface energy-driven processes.

scholarly journals Papillary Thyroid Cancer-Promoting Activities of Combined Oral Contraceptive Components

2020 ◽  
Vol 9 ◽  
pp. 1648
Author(s):  
Mehdi Hedayati ◽  
Sadegh Rajabi ◽  
Abdolrahim Nikzamir
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Reproductive Age ◽  
Papillary Thyroid ◽  
Scratch Assay ◽  
Diphenyltetrazolium Bromide ◽  
High Incidence ◽  
And Migration ◽  
The Relationship

Background: Thyroid cancer is more common in women at reproductive age, suggesting the relationship between its high-incidence and therapeutic use of hormonal medications, such as oral contraceptives (OCPs). The aim of this study was to identify the effect of low-dose combined OCP (LD-COC) on proliferation, apoptosis, and migration of human papillary thyroid cancer (PTC) BCPAP cell line. Materials and Methods: BCPAP cells were cultured and treated with the combination of 90nM levonorgestrel (LNG) and 20nM ethinylestradiol (EE) for 48 hours. Afterward, using 3-(4, 5-dimethylthiazol-2-yl) -2, 5-diphenyltetrazolium bromide (MTT) assay, the proliferation of the cells was measured. Apoptosis was determined by using a Caspase-3 ELISA kit. Migratory properties of combined LNG and EE were studied through wound scratch assay. The expression levels of pro-apoptotic factor BAX, anti-apoptotic factor Bcl2, and proliferation marker Ki67 were analyzed by quantitative reverse transcriptase polymerase chain reaction (qRT-PCR) and western blotting. Results: Upon treatment with the combination of LNG and EE, proliferation and migration of BCPAP cells were significantly enhanced. However, LNG and EE remarkably inhibited apoptosis of these cells. Furthermore, treating PTC cells with combined LNG and EE caused a marked increase in the expression of Bcl2 and Ki67 and a considerable decrease in BAX levels (P˂ 0.05). Conclusion: Our data linked the use of COCs and the progression and aggressiveness of PTC, suggesting the role of these hormonal compounds as promoting factors for PTC tumors. Despite these observations, further investigations will be required to fully establish the pathogenic impact of these medications on PTC. [GMJ.2020;9:e1648] 

scholarly journals Climate migration and the UK

2021 ◽  
Vol 9 ◽  
pp. 3-26
Author(s):  
Laurie Parsons
Keyword(s):  
Climate Change ◽  
Domestic Politics ◽  
Migration Policy ◽  
Political Landscape ◽  
Academic Scholarship ◽  
New Directions ◽  
And Migration ◽  
The Uk ◽  
The Relationship

This article discusses the relationship between climate change and migration in the context of the UK. After a brief overview of climate migration scholarship, it examines the framing of climate migration as a crisis in UK policy discourse, highlighting the disjuncture between policy and academic scholarship in this respect. Subsequently, it examines the reasons for this schism, exploring both the framing of climate migration within the UK media landscape and the securitisation of the topic within UK government policy. Finally, the article explores how the UK�s political landscape undergirds the political logic of climate finance, emphasising the role of British domestic politics in shaping the boundaries and direction of climate change as it manifests in governance. The article closes by exploring potential new directions in UK climate migration policy.

scholarly journals ZBTB7A, A Potential Biomarker for Prognosis and Immune Infiltrates, Inhibits Progression of Endometrial Cancer Based on Bioinformatics Analysis and Experiments

2020 ◽  
Author(s):  
Rong Geng ◽  
Yuhua Zheng ◽  
Donghua Zhou ◽  
Qingdong Li ◽  
Ruiman Li ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Zinc Finger Protein ◽  
Immune Cell ◽  
Vital Role ◽  
Marker Genes ◽  
Potential Biomarker ◽  
And Migration ◽  
The Relationship

Abstract Backgroud: ZBTB protein is an important member of the C2H2 zinc finger protein family. As a transcription factor, it is widely involved in the transcriptional regulation of genes, cell proliferation, differentiation, and apoptosis. However, the role of ZBTB7A in uterine corpus endometrial carcinoma (UCEC) is unclear.Methods: In our work, we assessed the importance of ZBTB 7A in UCEC. Firstly, Using Oncomine and Tumor Immunoassay Resource (TIMER) databases to evaluate the expression of ZBTB7A. Secondly, we explored the co expression network of ZBTB7A through the cBioPortal online tool, Metascape, and LinkedOmics. TIMER was also used to explore the relationship between ZB TB7A and tumor immu ne invasion, and to detect the correlation between the ZBTB7A and the marker genes related to immune infiltration. Finally, CKK8,migration, ChIP assays were introduced to partly validate ZBTB7A function in endometrialcancer cells.Results: We found t he ZBTB7A expression in TIMER was associated with various cancers, especially UCEC. The decreased expre ssion of ZBTB7A was markedly related to the stage and prognosis of UCEC. Furthermore, ZBTB7A was also related to the expression of various immune markers s uch as Neutrophils, Dendritic cell, T cell (general), Th1, Th2, and Finally, we verified that ZBTB7 A repressed E2F4 transcription and inhibited cell s proliferation and migration . These results indicate that ZBTB7A may play a vital role in regulating immune cellinfiltration in UCEC, and is a valuable prognostic marker.Conclusions:In summary, we demonstrate that ZBTB7A is notably downregulated in UCEC, play s a vital role in regu lating immune cell infiltration, possesses diagnostic and pr ognostic values and attenuated E2F4 transcription and cell proliferation , migration in vitro.

Overexpression of EI2BL promoted human non-small cell lung cancer progression by inducing cell EMT phenotype

2019 ◽  
Vol 73 (3) ◽  
pp. 139-146
Author(s):  
Hao-Ran Li ◽  
Bai-Quan Qiu ◽  
Jian Gao ◽  
Chun Jin ◽  
Jia-Hao Jiang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Proliferation ◽  
Western Blot ◽  
Blot Analysis ◽  
Small Cell ◽  
Small Cell Lung ◽  
Invasion And Migration ◽  
And Migration ◽  
The Relationship

AimsTo unveil the role of EI2BL in non-small cell lung cancer (NSCLC) and the relationship between expression of EI2BL and the prognosis of patients with NSCLC.MethodsImmunohistochemistry (IHC), western blot analysis, immunofluorescence and real-time quantitative PCR (RT-qPCR) were used to evaluate EI2BL protein and mRNA levels in NSCLC and corresponding peritumour tissues. Cell Counting Kit-8, transwell assay and wound healing assay were used to analyse the abilities of cell proliferation, invasion and migration. In addition, the analysis of epithelial-mesenchymal transition (EMT) markers was also assessed by western blot analysis, RT-qPCR and immunofluorescence. Tissue micro-array analysis of 200 NSCLC cases was used to assess the relationship between EI2BL expression and clinicopathological characteristics. Moreover, the prognostic role of EI2BL in 200 patients with NSCLC was evaluated by Cox regression models and Kaplan-Meier methods.ResultsElevated EI2BL expression was more common in NSCLC tissues than paired peritumour tissues in both mRNA and protein level. EI2BL promoted the proliferation, invasion and migration of NSCLC cells. In addition, aberrant EI2BL expression might modulate the expression of key molecules of EMT by ERK1/2 signal pathway. The expression of EI2BL was significantly associated with tumour stage, lymph node metastasis and tumour size. Moreover, higher expression of EI2BL in patients with NSCLC had a poor overall survival rate.ConclusionsOur study illustrated that elevated expression of EI2BL promoted NSCLC cell proliferation, migration and invasion and EI2BL overexpression may be a reliable biomarker of poor prognosis.

The Legacy of Conflict: Reconstruction and Migration in the Aftermath of Civil War in Tajikistan

2021 ◽  
pp. 019791832110254
Author(s):  
Michelle L. O’Brien
Keyword(s):  
Civil War ◽  
Logistic Regression Models ◽  
Resource Center ◽  
Combining Data ◽  
And Migration ◽  
Data Program ◽  
Development Resource ◽  
The Relationship

How do civil war and subsequent reconstruction efforts affect international migration? Although a wealth of evidence points to violent conflict’s effects on contemporaneous migration and although a rich body of literature examines development’s effects on migration, we know less about the intersection of conflict, development, and migration. This article examines the intersection of these factors nearly a decade after the 1992–1997 civil war in Tajikistan, combining data from the 2007 Tajikistan Living Standards Survey, the Uppsala Conflict Data Program, and original interviews. In a series of logistic regression models, I show that conflict fatalities do not have a direct effect on subsequent migration, while the number of years a district has had a development resource center directly increases the likelihood of migrating. However, the interaction between development and conflict is negative and significant. These findings suggest that conflict’s legacy does not directly impact the likelihood of respondents migrating but instead changes the nature of the relationship between development and migration. This finding illuminates conflict’s potential long-term consequences for migration and extends the migration-development nexus by addressing the role of conflict in the relationship between development and migration. In particular, it suggests that migration research in conflict-affected countries should incorporate measures of both conflict and development, even after a given conflict has ended.

scholarly journals Apotheosis or Apparition?: Bombay and the Village in 1990s Women‘s Cinema

Film Studies ◽  
2007 ◽  
Vol 11 (1) ◽  
pp. 1-13 ◽  
Author(s):  
Rashmi Sawhney
Keyword(s):  
National Development ◽  
Economic Context ◽  
Women's Cinema ◽  
And Migration ◽  
Relations Of Power ◽  
The Village ◽  
The Relationship

This article examines the representation of Bombay in Aruna Raje‘s Rihaee (1988) and Sai Paranjpyes Disha (1990). It has been argued here that in both films, Bombay functions as a narrative anchor to the fictive village, which is depicted as the locus of Indian modernity. Symbolism of the village-city trope is used to reorganise the syntagm of modernity-location-gender in new relations of power and also to present alternative visions of national development within the socio-economic context of 1990s liberalisation in India. The dialectic between city and village in these films emphasises the role of memory and migration in women‘s cinema, and also serves as a means to probing the relationship between gender and films in the postcolonial context.

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