A New History of Vaccines for Infectious Diseases

2022 ◽  
Keyword(s):  
Infectious Diseases ◽  
History Of

Organization of restrictive quarantine measures to prevent especially dangerous infections

2020 ◽  
pp. 6-11
Author(s):  
Petr Ilyin
Keyword(s):  
Infectious Diseases ◽  
Clinical Symptoms ◽  
International Health ◽  
World Health ◽  
The World ◽  
History Of ◽  
Entire History ◽  
Health Organization ◽  
Former Ussr ◽  
Health Regulations

Especially dangerous infections (EDIs) belong to the conditionally labelled group of infectious diseases that pose an exceptional epidemic threat. They are highly contagious, rapidly spreading and capable of affecting wide sections of the population in the shortest possible time, they are characterized by the severity of clinical symptoms and high mortality rates. At the present stage, the term "especially dangerous infections" is used only in the territory of the countries of the former USSR, all over the world this concept is defined as "infectious diseases that pose an extreme threat to public health on an international scale." Over the entire history of human development, more people have died as a result of epidemics and pandemics than in all wars combined. The list of especially dangerous infections and measures to prevent their spread were fixed in the International Health Regulations (IHR), adopted at the 22nd session of the WHO's World Health Assembly on July 26, 1969. In 1970, at the 23rd session of the WHO's Assembly, typhus and relapsing fever were excluded from the list of quarantine infections. As amended in 1981, the list included only three diseases represented by plague, cholera and anthrax. However, now annual additions of new infections endemic to different parts of the earth to this list take place. To date, the World Health Organization (WHO) has already included more than 100 diseases in the list of especially dangerous infections.

scholarly journals A Framework of an Integrated Livestock Vehicle Trajectory Database Using Digital Tachograph Data

2021 ◽  
Vol 13 (5) ◽  
pp. 2694
Author(s):  
Heehyeon Jeong ◽  
Jungyeol Hong ◽  
Dongjoo Park
Keyword(s):  
Infectious Diseases ◽  
African Swine Fever Virus ◽  
African Swine Fever ◽  
Disease Spread ◽  
Transportation Engineering ◽  
The Public ◽  
Vehicle Trajectories ◽  
History Of ◽  
Vehicle Trajectory ◽  
Livestock Diseases

The outbreak of African swine fever virus has raised global concerns regarding epidemic livestock diseases. Therefore, various studies have attempted to prevent and monitor epidemic livestock diseases. Most of them have emphasized that integrated studies between the public health and transportation engineering are essential to prevent the livestock disease spread. However, it has been difficult to obtain big data related to the mobility of livestock-related vehicles. Thus, it is challenging to conduct research that comprehensively considers cargo vehicles’ movement carrying livestock and the spread of livestock infectious diseases. This study developed the framework for integrating the digital tachograph data (DTG) and trucks’ visit history of livestock facility data. The DTG data include commercial trucks’ coordinate information, but it excludes actual livestock-related vehicle trajectories such as freight types and facility visit history. Therefore, the integrated database we developed can be used as a significant resource for preventing the spread of livestock epidemics by pre-monitoring livestock transport vehicles’ movements. In future studies, epidemiological research on infectious diseases and livestock species will be able to conduct through the derived integrating database. Furthermore, the indicators of the spread of infectious diseases could be suggested based on both microscopic and macroscopic roadway networks to manage livestock epidemics.

Physical Development and Medical History of Children Who Were Treated Antenatally With Corticosteroids to Prevent Respiratory Distress Syndrome: A 10- to 12-Year Follow-up

PEDIATRICS ◽  
1990 ◽  
Vol 86 (1) ◽  
pp. 65-70 ◽  
Author(s):  
H. Smolders-de Haas ◽  
J. Neuvel ◽  
B. Schmand ◽  
p. E. Treffers ◽  
J. G. Koppe ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Medical History ◽  
Distress Syndrome ◽  
Hospital Admissions ◽  
Controlled Trial ◽  
Ophthalmological Examination ◽  
Double Blind ◽  
History Of

Potential side effects of antenatal administration of corticosteroids to prevent neonatal respiratory distress syndrome were studied in 10- to 12-year-old children whose mothers had participated in a randomized, double-blind, placebo-controlled trial of betamethasone. The children had a general physical examination; parents were interviewed about the medical history of their child with special attention to infectious diseases; growth data were collected; and a developmental neurological examination, an ophthalmological examination, and a lung function test were conducted. In the corticosteroid group significantly more hospital admissions because of infectious diseases during the first years of life were reported. On the other variables no differences between the corticoid and the placebo groups were found.

scholarly journals Kejadian Leptospirosis pada Anjing di Daerah Istimewa Yogyakarta (CASE OF CANINE LEPTOSPIROSIS IN THE CITY OF YOGYAKARTA)

2017 ◽  
Vol 18 (3) ◽  
pp. 403
Author(s):  
Guntari Titik Mulyani ◽  
Sri Hartati ◽  
Yuli Santoso ◽  
Kurnia Kurnia ◽  
Agung Budi Pramono ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Clinical Symptoms ◽  
Emerging Infectious Diseases ◽  
Agglutination Test ◽  
Microscopic Agglutination Test ◽  
Severe Illness ◽  
Leptospira Interrogans ◽  
Veterinary Research ◽  
History Of ◽  
The City

Leptospirosis is a zoonotic disease, which is caused by Leptospira interrogans. The incidence of leptospirosis in dogs varies according to region and season, and is considered as emerging infectious diseases in humans. Clinical symptoms of leptospirosis in dogs vary greatly, some dogs are asymptomatic, with mild symptoms, and others progress to severe illness until death. The study aims to determine cases of canine leptospirosis in Yogyakarta, and identify the serovar that infect them. A total of 20 dogs without symptoms, with mild symptoms, to severe symptoms of leptospirosis were collected their serum and further tested using Microscopic Agglutination Test (MAT) conducted at the Center for Veterinary Research (BBLitvet) Bogor. History of vaccination is recorded as a consideration in interpreting the MAT results. The results showed that three out of the 20 samples were positive leptospirosis. Of the three positive samples, one was identified as serovar bataviae, another one as serovar bataviae and tarrasovi, and the last as serovar bataviae, tarrasovi, ichterohaemorrhagiae, canicola, celledoni, pyrogenes, cynopteri, and rachmati, respectively. The three dogs with leptospirosis showed similar clinical symptoms i.e. Anorexia, lethargy, and fever. It can be concluded that there are cases of canine leptospirosis in Yogyakarta which is predominantly caused by Leptospira interrogans serovar bataviae. ABSTRAK Leptospirosis adalah penyakit zoonosis, yang disebabkan oleh Leptospira interrogans. Kejadian leptospirosis pada anjing bervariasi menurut wilayah dan musim, dan dianggap sebagai penyakit menular yang muncul pada manusia. Gejala klinis leptospirosis pada anjing sangat bervariasi, beberapa anjing tanpa menunjukkan gejala, dengan gejala ringan, dan yang lain melanjut menjadi penyakit yang parah sampai kematian. Penelitian ini bertujuan untuk mengetahui kasus leptospirosis pada anjing di Propinsi Daerah Istimewa Yogyakarta, dan mengidentifikasi serovar yang menginfeksinya. Sebanyak 20 ekor anjing tanpa gejala, dengan gejala ringan, sampai gejala parah leptospirosis diambil serumnya guna pemeriksaan Microscopic Agglutination Test (MAT) yang dilaksanakan di Balai Besar Penelitian Veteriner (BBLitvet), Bogor. Sejarah vaksinasi dicatat sebagai bahan pertimbangan dalam menginterpretasi hasil pemeriksaan MAT. Hasil penelitian menunjukkan bahwa tiga dari 20 sampel positif leptospirosis. Satu sampel positif terhadap serovar Bataviae, satu sampel positif terhadap serovar Bataviae dan Tarrasovi, dan satu sampel lagi positif terhadap serovar Bataviae, Tarrasovi, Ichterohaemorrhagiae, Canicola, Celledoni, Pyrogenes, Cynopteri, dan Rachmati. Anjing yang positif leptospirosis menunjukkan gejala klinis yang sama berupa anoreksia, kelemahan, dan demam. Dari hasil penelitian ini dapat disimpulkan bahwa terdapat kasus leptospirosis pada anjing di Yogyakarta yang penyebabnya dominan oleh Leptospira interrogans serovar Bataviae.

scholarly journals Dermoscopy revealing a case of Tinea Nigra*

2013 ◽  
Vol 88 (1) ◽  
pp. 128-129 ◽  
Author(s):  
Paulo Ricardo Criado ◽  
Lívia Delgado ◽  
Gustavo Alonso Pereira
Keyword(s):  
Infectious Diseases ◽  
Diagnostic Tool ◽  
Glabrous Skin ◽  
Daily Routine ◽  
Brown Patch ◽  
The Past ◽  
History Of ◽  
Tinea Nigra ◽  
Skin Conditions

Dermoscopy has being used over the past twenty years as a noninvasive aid in the diagnosis of innumerable skin conditions, including infectious diseases and infestations (Entodermoscopy).Tinea nigra is a superficial phaeohyfomycosis that affects mainly the glabrous skin of palms and soles. We describe a 14 year-old girl with a three-month history of an enlarging brown patch of her hand diagnosed as Tinea Nigra following clinical and dermoscopy examination.These images emphasize the importance of dermoscopy as a diagnostic tool in the daily routine of dermatologists.

scholarly journals THE RELATIONSHIP OF VITAMIN A SUPPLEMENTATION, GIVING IMMUNIZATION, AND HISTORY OF INFECTION DISEASE WITH THE STUNTING OF CHILDREN AGED 24-59 MONTHS IN PUSKESMAS MULYOREJO, SURABAYA

2021 ◽  
Vol 10 (1) ◽  
pp. 72
Author(s):  
Melvanda Gisela Putri ◽  
Roedi Irawan ◽  
Indri Safitri Mukono
Keyword(s):  
Vitamin A ◽  
Infectious Diseases ◽  
Secondary Data ◽  
Z Score ◽  
Chi Square ◽  
Cross Sectional ◽  
Vitamin A Supplementation ◽  
Chi Square Test ◽  
History Of ◽  
The Relationship

ABSTRAKLatar Belakang: Stunting merupakan suatu istilah yang menggambarkan kondisi pertumbuhan tinggi badan kurang berdasarkan umur disesuaikan dengan Z-Score (<-2SD). Stunting pada balita dapat diakibatkan oleh kurangnya asupan zat gizi yang diperlukan bagi pertumbuhan anak. Penelitian dilakukan untuk mengetahui hubungan suplementasi vitamin A, pemberian imunisasi dan riwayat penyakit infeksi yakni diare dan ISPA terhadap kejadian stunting.Tujuan: Mengetahui hubungan suplementasi vitamin A, pemberian imunisasi, dan penyakit infeksi terhadap stunting pada anak usia 24-59 bulan di Puskesmas Mulyorejo, Surabaya.Metode: Penelitian ini merupakan penelitian analitik observasional dengan metode cross sectional. Besar sampel adalah 107 anak usia 24-59 bulan di Puskesmas Mulyorejo, Surabaya. terdiri dari 25 anak kelompok stunting dan 82 anak kelompok non- stunting. Cara pengambilan data melalui data sekunder posyandu dan wawancara langsung orang tua anak dengan pengisian kuisioner. Data dianalisis menggunakan uji Chi-Square, Fisher Exact, dan Mann Whitney.Hasil: Penelitian ini menunjukkan hasil terdapat hubungan suplementasi vitamin A dengan stunting (p=0,000), tidak ada hubungan antara pemberian imunisasi terhadap stunting (p=0,332). Dalam riwayat penyakit infeksi, frekuensi diare dan ISPA ditemukan tidak ada hubungan dengan  stunting (p=0,053 dan p=0,082), begitu pula pada lama diare dan lama ISPA tidak berhubungan dengan stunting (p= 0,614 dan p=0,918).Kesimpulan: Suplementasi vitamin A berhubungan signifikan dengan stunting yang diamati pada anak usia 24-59 bulan di Puskesmas Mulyorejo, Surabaya. Kata kunci: kejadian stunting, vitamin A, imunisasi, penyakit infeksi, anak usia 24-59 bulanABSTRACTBackground: Stunting is a term that describes condition of lower height-for-age Z-Score (<-2SD). Stunting among children can be caused by a lack of nutrients needed for children's growth. This study was conducted to determine the relationship between vitamin A supplementation, immunization and a history of infectious diseases, namely diarrhea and ARI to the incidence of stunting.Objectives: To determine the relationship between vitamin A supplementation, immunization, and history of infectious disease with the incidence of stunting in children aged 24-59 months at Puskesmas Mulyorejo, Surabaya.Methods: This study was an observational analytic study with cross sectional method. The sample size was 107 children aged 24-59 months at Puskesmas Mulyorejo, Surabaya. This study consisted of 25 children in the stunting group and 82 children in the non-stunting group. The method of data collection was through secondary data from posyandu and direct interviews with parents by filling out questionnaires. Data were analyzed using the chi-square test, fisher exact, and Mann Whitney.Results: The results of this study indicated that there was a relationship between vitamin A supplementation and with stunting (p = 0.000). There was no relationship between immunization and stunting (p = 0.332). In the history of infectious diseases, the frequency of diarrhea and ARI was found to have no relationship with stunting (p = 0.053 and p = 0.082), as well as the duration of diarrhea and duration of ARI there was no association with the stunting (p = 0.614 and p = 0.918).Conclusion: Vitamin A supplementation has significant relationship with stunting in children aged 24-59 months at Puskesmas Mulyorejo, Surabaya.

scholarly journals The Principles of Antibody Therapy for Infectious Diseases with Relevance for COVID-19

mBio ◽  
2021 ◽  
Vol 12 (2) ◽  
Author(s):  
Arturo Casadevall ◽  
Liise-anne Pirofski ◽  
Michael J. Joyner
Keyword(s):  
Infectious Diseases ◽  
Antimicrobial Agents ◽  
Severe Disease ◽  
Antibody Therapy ◽  
Course Of Disease ◽  
Medical Practitioners ◽  
History Of ◽  
Serum Therapy ◽  
Effective Lessons ◽  
Further Development

ABSTRACT Antibody therapies such as convalescent plasma and monoclonal antibodies have emerged as major potential therapeutics for coronavirus disease 2019 (COVID-19). Immunoglobulins differ from conventional antimicrobial agents in that they mediate direct and indirect antimicrobial effects that work in concert with other components of the immune system. The field of infectious diseases pioneered antibody therapies in the first half of the 20th century but largely abandoned them with the arrival of conventional antimicrobial therapy. Consequently, much of the knowledge gained from the historical development and use of immunoglobulins such as serum and convalescent antibody therapies was forgotten; principles and practice governing their use were not taught to new generations of medical practitioners, and further development of this modality stalled. This became apparent during the COVID-19 pandemic in the spring of 2020 when convalescent plasma was initially deployed as salvage therapy in patients with severe disease. In retrospect, this was a stage of disease when it was less likely to be effective. Lessons of the past tell us that antibody therapy is most likely to be effective when used early in respiratory diseases. This article puts forth three principles of antibody therapy, namely, specificity, temporal, and quantitative principles, connoting that antibody efficacy requires the administration of specific antibody, given early in course of disease in sufficient amount. These principles are traced to the history of serum therapy for infectious diseases. The application of the specificity, temporal, and quantitative principles to COVID-19 is discussed in the context of current use of antibody therapy against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

scholarly journals Patterns of smallpox mortality in London, England, over three centuries

PLoS Biology ◽  
2020 ◽  
Vol 18 (12) ◽  
pp. e3000506
Author(s):  
Olga Krylova ◽  
David J. D. Earn
Keyword(s):  
Public Health ◽  
Infectious Disease ◽  
Time Series ◽  
Spectral Analysis ◽  
Infectious Diseases ◽  
Health Policies ◽  
Human Populations ◽  
Public Health Policies ◽  
History Of ◽  
History Of Control

Smallpox is unique among infectious diseases in the degree to which it devastated human populations, its long history of control interventions, and the fact that it has been successfully eradicated. Mortality from smallpox in London, England was carefully documented, weekly, for nearly 300 years, providing a rare and valuable source for the study of ecology and evolution of infectious disease. We describe and analyze smallpox mortality in London from 1664 to 1930. We digitized the weekly records published in the London Bills of Mortality (LBoM) and the Registrar General’s Weekly Returns (RGWRs). We annotated the resulting time series with a sequence of historical events that might have influenced smallpox dynamics in London. We present a spectral analysis that reveals how periodicities in reported smallpox mortality changed over decades and centuries; many of these changes in epidemic patterns are correlated with changes in control interventions and public health policies. We also examine how the seasonality of reported smallpox mortality changed from the 17th to 20th centuries in London.

scholarly journals Human T Lymphotropic virus-1 associated gastrointestinal histoplasmosis in Peru

2011 ◽  
Vol 5 (06) ◽  
pp. 484-488 ◽  
Author(s):  
Carlos Canelo-Aybar ◽  
Jose Cuadra-Urteaga ◽  
Fernando Atencia ◽  
Franco Romani
Keyword(s):  
Infectious Diseases ◽  
Immunosuppressive Drugs ◽  
Chronic Diarrhoea ◽  
Gastrointestinal Involvement ◽  
T Lymphotropic Virus ◽  
Documented Case ◽  
Histologic Evidence ◽  
Gastrointestinal Histoplasmosis ◽  
History Of

We report a 72-year-old patient with chronic diarrhoea and histologic evidence of gastrointestinal histoplasmosis. He had no history of HIV or of taking immunosuppressive drugs. The patient was found to be a carrier of Human T-lymphotropic virus-1, a condition associated with inflammatory, lymphoproliferative, and opportunistic infectious diseases. To our knowledge, there are only three previous cases reporting this coinfection and this is the first documented case with gastrointestinal involvement.

Sign in / Sign up

Export Citation Format

Share Document