scholarly journals Global data analysis and risk factors associated with morbidity and mortality of COVID-19

Gene Reports ◽  
2022 ◽  
pp. 101505
Author(s):  
Sina Salajegheh Tazerji ◽  
Fatemeh Shahabinejad ◽  
Mahya Tokasi ◽  
Mohammad Ali Rad ◽  
Muhammad Sajjad Khan ◽  
...  
2019 ◽  
Vol 7 (19) ◽  
pp. 3302-3306
Author(s):  
Nenni Dwi Aprianti Lubis ◽  
Sri Amelia ◽  
Nurfida Khairina Arrasyid ◽  
Muhammad Fakhrur Rozi

BACKGROUND: Foodborne disease (FBD) contributes several outbreaks worsening health quality of world population. Many risk factors associated with FBD are related to its processing, preparation, and storage as well as handling practice. AIM: The study aimed to evaluate several proposed risk factors of foodborne disease existed among school-aged children and food-handlers in the school environment. MATERIAL AND METHODS: The descriptive cross-sectional study enrolled 124 students consisting of 64 females and 60 males in two different public schools, 064024 and 066656, Medan, Indonesia, between April and August 2018. The bacterial and parasitological examination was carried out in Microbiology and Parasitology Department. Food-handlers were assessed their appropriateness using standardised questionnaire merit to the guidelines enacted by the Ministry of Health, Indonesia (Kepmenkes RI No.942 / Menkes / SK / VII / 2003 adapted from WHO guidelines) entitled food-handlers sanitation-hygiene requirement guidelines. Data analysis was conducted using logistic regression. RESULTS: The study obtained that there were no food-handlers performed basic principles rules producing high-risk environment and posing a threat to children. Suspected-FBD also found in 55 or 44.4% students, and it was significantly related to several risk factors such as nail hygiene, knowledge level, nail-trimming behaviour, and hand-washing behaviour among students. Data analysis revealed modeling risk factor, Y = 23.440 + 2.003 (Nail hygiene) + 1.294 (Knowledge level) + 5.025 (Nail trimming behavior) + 7.007 (Hand-washing behavior) from logistic regression equation. CONCLUSION: Poor hygiene and sanitation of food-handlers and children per se provide a supportive environment in producing FBDs.


2020 ◽  
Vol 148 ◽  
Author(s):  
M. Z. Islam ◽  
B. K. Riaz ◽  
A. N. M. S. Islam ◽  
F. Khanam ◽  
J. Akhter ◽  
...  

Abstract Diverse risk factors intercede the outcomes of coronavirus disease 2019 (COVID-19). We conducted this retrospective cohort study with a cohort of 1016 COVID-19 patients diagnosed in May 2020 to identify the risk factors associated with morbidity and mortality outcomes. Data were collected by telephone-interview and reviewing records using a questionnaire and checklist. The study identified morbidity and mortality risk factors on the 28th day of the disease course. The majority of the patients were male (64.1%) and belonged to the age group 25–39 years (39.4%). Urban patients were higher in proportion than rural (69.3% vs. 30.7%). Major comorbidities included 35.0% diabetes mellitus (DM), 28.4% hypertension (HTN), 16.6% chronic obstructive pulmonary disease (COPD), and 7.8% coronary heart disease (CHD). The morbidity rate (not-cured) was 6.0%, and the mortality rate (non-survivor) was 2.5%. Morbidity risk factors included elderly (AOR = 2.56, 95% CI = 1.31–4.99), having comorbidity (AOR = 1.43, 95% CI = 0.83–2.47), and smokeless tobacco use (AOR = 2.17, 95% CI = 0.84–5.61). The morbidity risk was higher with COPD (RR = 2.68), chronic kidney disease (CKD) (RR = 3.33) and chronic liver disease (CLD) (RR = 3.99). Mortality risk factors included elderly (AOR = 7.56, 95% CI = 3.19–17.92), having comorbidity (AOR = 5.27, 95% CI = 1.88–14.79) and SLT use (AOR = 1.93, 95% CI = 0.50–7.46). The mortality risk was higher with COPD (RR = 7.30), DM (RR = 2.63), CHD (RR = 4.65), HTN (RR = 3.38), CKD (RR = 9.03), CLD (RR = 10.52) and malignant diseases (RR = 9.73). We must espouse programme interventions considering the morbidity and mortality risk factors to condense the aggressive outcomes of COVID-19.


2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e15544-e15544
Author(s):  
Jingdong Liu ◽  
Haojie Li ◽  
Gang Zhao ◽  
Zekuan Xu ◽  
Guoxin Li ◽  
...  

e15544 Background: The incidence rate of proximal gastric cancer has been rising steadily, and laparoscopic total gastrectomy (LTG) has been widely adopted. However, the safety of LTG still lacks solid evidence to prove. The aim of this study was to evaluate morbidity and mortality of LTG, and determine the risk factors associated with early postoperative complications. Methods: A retrospective multicenter study was carried out in China, and medical records of 109 gastric cancer patients receiving LTG during September 2014 and June 2016 were retrieved from the database. Patient characteristics, surgical outcomes, and postoperative morbidities and mortalities were analyzed. Results: Morbidity and mortality rates were 22.0% and 0% respectively. Pulmonary infection (13.8%, n = 15) was the most common complication. Most complications were grade II (15.5%, n = 17) according to the Clavien-Dindo classification. Multivariable analysis identified comorbidity, type of reconstruction method (TLTG) were independent risk factors of early postoperative complications. Comorbidity was the only independent risk factor of complications graded more than II. Diabetes mellitus was found correlated with surgical complication in subgroup analysis. Conclusions: LTG is safe and technically feasible in treating gastric cancer. Careful selection of patients without comorbidity and applying laparoscopy-assisted total gastrectomy instead of totally laparoscopic total gastrectomy may decrease postoperative complications.


2018 ◽  
Vol 128 (1) ◽  
pp. 13-21 ◽  
Author(s):  
Brittany N. Burton ◽  
Sapideh Gilani ◽  
Milli Desai ◽  
Robert Saddawi-Konefka ◽  
Lindia Willies-Jacobo ◽  
...  

Objectives: Pediatric sinus surgery is indicated for a wide range of sinonasal and skull base pathologies, but it is most commonly performed for recalcitrant chronic rhinosinusitis or complicated acute sinusitis. The authors aim to report medical risk factors of morbidity and mortality following inpatient sinus surgery in the pediatric population. Methods: Using data from the Kids’ Inpatient Database from 2003 to 2012, patients with International Classification of Diseases, Ninth Revision, procedure codes for primary sinus surgery were identified. Mixed-effect multivariable logistic regression was used to identify risk factors of inpatient postoperative morbidity and mortality. Results: The final sample included a weighted estimate of 4965 pediatric patients. The rates of inpatient morbidity and mortality were 6% and 1%, respectively. Respiratory complications (2.5%) were the most prevalent postoperative adverse events. The most prevalent comorbidities were chronic sinusitis (59.8%), acute sinusitis (27.8%), and cystic fibrosis (26.4%). Compared with patients who did not experience any morbidity, patients with inpatient morbidity had higher rates of pneumonia, mycoses, and nasal or paranasal benign neoplasm ( P < .05). The odds of inpatient morbidity and mortality were highest for patients with leukemia (odds ratio, 2.74; 95% confidence interval, 1.59-4.72; P < .001) and mycoses (odds ratio, 15.84; 95% confidence interval, 6.45-38.89; P < .001), respectively. Conclusions: This study is the first to report the national comorbidity burden and risk factors for postoperative adverse events following inpatient sinus surgery. Knowledge of the comorbidities and independent factors associated with morbidity and mortality will help in directing preoperative optimization and counseling. Level of Evidence: 2c


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