Surfactant-free synthesis of high surface area silica nanoparticles derived from rice husks by employing the Taguchi approach

Over the past few decades, nanoparticles have been attracting significant attention of researches in chemical, biomedical, pharmaceutical sciences, due to their unique physicochemical properties. This includes ultra small size, large surface area, good biocompatibility and high reactivity. In particular, nanoparticles are promising for pharmaceutical and biomedical fields, as they can be applied as drug carriers and diagnostic tools. Among nanomaterials for biomedical application, silica nanoparticles exhibit great potential due to their straightforward synthesis and separation, low cost, safety, biocompatibility and possibility to further functionalization. Silica nanoparticles have been attractive for pharmaceutical science due to their unique properties, such as tunable size, high surface area and large pore volume, and potential in biomedical application as drug and gene delivery vectors and bioimaging agents. However, some of their properties remain poorly investigated. This short communication discusses the main routes for synthesis of silica nanoparticles, their properties and opportunities for their application in pharmaceutical and biomedical industries, as well as a few challenges in the development of silica-based systems that need to be overcome.

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Hyper-Crosslinked Polymer Nanocomposites Containing Mesoporous Silica Nanoparticles with Enhanced Adsorption Towards Polar Dyes

Polymers ◽

10.3390/polym12061388 ◽

2020 ◽

Vol 12 (6) ◽

pp. 1388

Author(s):

Marco Guerritore ◽

Rachele Castaldo ◽

Brigida Silvestri ◽

Roberto Avolio ◽

Mariacristina Cocca ◽

...

Keyword(s):

Mesoporous Silica ◽

Silica Nanoparticles ◽

Surface Area ◽

Organic Dyes ◽

Mesoporous Silica Nanoparticles ◽

High Surface ◽

High Surface Area ◽

Reactive Dye ◽

New Strategy ◽

Enhanced Adsorption

The development of new styrene-based hyper-crosslinked nanocomposites (HCLN) containing mesoporous silica nanoparticles (MSN) is reported here as a new strategy to obtain functional high surface area materials with an enhanced hydrophilic character. The HCLN composition, morphology and porous structure were analyzed using a multi-technique approach. The HCLN displayed a high surface area (above 1600 m2/g) and higher microporosity than the corresponding hyper-crosslinked neat resin. The enhanced adsorption properties of the HCLN towards polar organic dyes was demonstrated through the adsorption of a reactive dye, Remazol Brilliant Blue R (RB). In particular, the HCLN containing 5phr MSN showed the highest adsorption capacity of RB.

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Synthesis and characterization of mesalamine silica nanoparticles

Current Drug Therapy ◽

10.2174/1574885516666211207100200 ◽

2021 ◽

Vol 16 ◽

Author(s):

Balaji Maddiboyina ◽

Ramya Krishna Nakkala ◽

Prasanna Kumar Desu ◽

Vikas Jhawat

Keyword(s):

Particle Size ◽

Silica Nanoparticles ◽

Surface Area ◽

High Surface ◽

High Surface Area ◽

Silica Nanoparticle ◽

Water Soluble ◽

Infrared Spectrometry ◽

Burst Release ◽

Wide Range

Background: Nanoparticles made of silica are new materials that can be used in a wide range of drug delivery methods because they are biocompatible and biodegradable. Mesalamine, a classic water-soluble medication, remains loaded into the synthesized silica nanoparticle and is considered for sustained release proficiency. Precipitation approach using high surface area and pore volume tetraethyl orthosilicate yielded mesalamine-loaded silica nanoparticles. Methods: The drug-loaded nanoparticle was created and produced using two different techniques. Fourier transform infrared spectrometry, differential scanning calorimetry, X-ray powder diffraction, Brauer Emmett teller, scanning electron microscopy, particle size measurements, and dissolution investigations have all been used to analyse the substance in some way or another. Results: Because of the high surface area, well-known results like the complete silica nanoparticle created using method-2 remained mesoporous. The onset peak of the method-2 formulation's DSC was 182.27°c, and the offset peak was 192.14°c, consistent with the DSC results. The particle size range varies from 205-225nm. The results demonstrate that the uptake of the mesalamine by burst release it for 30 minutes initial, followed by sustained maintenance of dose even after 240 minutes. The results indicate that the loading process has an effect on the extent of loading. When silica nanoparticles were impregnated with mesalamine, the amount of the drug contained was significantly higher than when they were wetted. Conclusion: In addition, the XRD results show that both the pure mesalamine and the formulation did not show any polymorphic deviation.

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Mesoporous Graphitic Carbon Nitrides Decorated with Cu Nanoparticles: Efficient Photocatalysts for Degradation of Tartrazine Yellow Dye

Nanomaterials ◽

10.3390/nano8090636 ◽

2018 ◽

Vol 8 (9) ◽

pp. 636 ◽

Cited By ~ 6

Author(s):

Tao Zhang ◽

Isis Souza ◽

Jiahe Xu ◽

Vitor Almeida ◽

Tewodros Asefa

Keyword(s):

Silica Nanoparticles ◽

Surface Area ◽

Synergistic Effects ◽

High Surface ◽

High Surface Area ◽

Graphitic Carbon ◽

Charge Carriers ◽

High Porosity ◽

Cu Nanoparticles ◽

Excellent Photocatalytic Activity

A series of mesoporous graphitic carbon nitride (mpg-C3N4) materials are synthesized by directly pyrolyzing melamine containing many embedded silica nanoparticles templates, and then etching the silica templates from the carbonized products. The mass ratio of melamine-to-silica templates and the size of the silica nanoparticles are found to dictate whether or not mpg-C3N4 with large surface area and high porosity form. The surfaces of the mpg-C3N4 materials are then decorated with copper (Cu) nanoparticles, resulting in Cu-decorated mpg-C3N4 composite materials that show excellent photocatalytic activity for degradation of tartrazine yellow dye. The materials’ excellent photocatalytic performance is attributed to their high surface area and the synergistic effects created in them by mpg-C3N4 and Cu nanoparticles, including the Cu nanoparticles’ greater ability to separate photogenerated charge carriers from mpg-C3N4.

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