scholarly journals The apparent permeability and the amplification factor of magnetic wires and wire arrays

2021 ◽  
Vol 527 ◽  
pp. 167726
Author(s):  
P. Ripka ◽  
V. Grim ◽  
M. Mirzaei
Sensors ◽  
2020 ◽  
Vol 21 (1) ◽  
pp. 3
Author(s):  
Pavel Ripka ◽  
Vaclav Grim ◽  
Mehran Mirzaei ◽  
Diana Hrakova ◽  
Janis Uhrig ◽  
...  

Soft magnetic wires and microwires are currently used for the cores of magnetic sensors. Due to their low demagnetization, they contribute to the high sensitivity and the high spatial resolution of fluxgates, Giant Magnetoimpedance (GMI), and inductive sensors. The arrays of nanowires can be prepared by electrodeposition into predefined pores of a nanoporous polycarbonate membrane. While high coercivity arrays with square loops are convenient for information storage and for bistable sensors such as proximity switches, low coercivity cores are needed for linear sensors. We show that coercivity can be controlled by the geometry of the array: increasing the diameter of nanowires (20 µm in length) from 30 nm to 200 nm reduced the coercivity by a factor of 10, while the corresponding decrease in the apparent permeability was only 5-fold. Finite element simulation of nanowire arrays is important for sensor development, but it is computationally demanding. While an array of 2000 wires can be still modelled in 3D, this is impossible for real arrays containing millions of wires. We have developed an equivalent 2D model, which allows us to solve these large arrays with acceptable accuracy. Using this tool, we have shown that as a core of magnetic sensors, nanowires are efficiently employed only together with microcoils with diameter comparable to the nanowire length.


1993 ◽  
Vol 265 (2) ◽  
pp. H543-H552 ◽  
Author(s):  
Y. Yuan ◽  
W. M. Chilian ◽  
H. J. Granger ◽  
D. C. Zawieja

This study reports measurements of albumin permeability in isolated coronary venules. The isolated microvessel technique allows the quantification of transmural exchange of macromolecules under tightly controlled physical and chemical conditions. Transvenular exchange of albumin was studied in isolated coronary venules during alterations in filtration rate caused by changes in intravascular pressure. The apparent permeability coefficient of albumin (Pa) at an intraluminal pressure of 11 cmH2O was 3.92 +/- 0.43 x 10(-6) cm/s. Elevating intraluminal pressure to 16 and 21 cmH2O increased Pa to 5.13 +/- 0.57 x 10(-6) and 6.78 +/- 0.66 x 10(-6) cm/s, respectively. Calculation of the true diffusive permeability coefficient of albumin (Pd) at zero filtration rate was 1.54 x 10(-6) cm/s. The product of hydraulic conductance (Lp) and (1 - sigma), where sigma is the solute reflection coefficient, was 3.25 x 10(-7) cm.s-1 x cmH2O-1. At a net filtration pressure of 4-5 cmH2O, diffusion accounts for > 60% of total albumin transport across the venular wall. Transmural albumin flux is very sensitive to filtration rate, rising 6.7% for each cmH2O elevation of net filtration pressure. At 11 cmH2O net filtration pressure, convection accounts for nearly 70% of net albumin extravasation from the venular lumen. We suggest that the isolated coronary venule is a suitable preparation for the study of solute exchange in the heart.


Chemosensors ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 104
Author(s):  
Hung-Yang Kuo ◽  
Wei-Riu Cheng ◽  
Tzu-Heng Wu ◽  
Horn-Jiunn Sheen ◽  
Chih-Chia Wang ◽  
...  

This paper presents the synthesis and evaluation of a carbon molecular sieve membrane (CMSM) grown inside a MEMS-fabricated μ-preconcentrator for sampling highly volatile organic compounds. An array of µ-pillars measuring 100 µm in diameter and 250 µm in height were fabricated inside a microfluidic channel to increase the attaching surface for the CMSM. The surface area of the CMSM was measured as high as 899 m2/g. A GC peak amplification factor >2 × 104 was demonstrated with gaseous ethyl acetate. Up to 1.4 L of gaseous ethanol at the 100 ppb level could be concentrated without exceeding the capacity of this microchip device. Sharp desorption chromatographic peaks (<3.5 s) were obtained while using this device directly as a GC injector. Less volatile compounds such as gaseous toluene, m-xylene, and mesitylene appeared to be adsorbed strongly on CMSM, showing a memory effect. Sampling parameters such as sample volatilities, sampling capacities, and compound residual issues were empirically determined and discussed.


2021 ◽  
pp. 014459872199978
Author(s):  
Bingyu Ji ◽  
Yingfu He ◽  
Yongqiang Tang ◽  
Shu Yang

The low-frequency pulse wave makes the velocity of the fluid in the reservoir fluctuate dramatically, which results in a remarkable inertia force. The Darcy’s law was inapplicable to the pulse flow with strong effect of inertial force. In this paper, the non-Darcy flow equation and the calculation method of capillary number of pressure pulse displacement are established. The pressure pulse experiments of single-phase and two- phase flow are carried out. The results show that the periodic change of velocity can decrease the seepage resistance and enhance apparent permeability by generating the inertial force. The higher the pulse frequency improves the apparent permeability by enhancing influence of inertial force. The increase of apparent permeability of high permeability core is larger than that of low permeability core, which indicates that inertial force is more prominent in high permeability reservoir. For the water-oil two-phase flow, inertia force makes the relative permeability curve move towards right, and the equal permeability point becomes higher. In other words, with the increase of capillary number, part of residual oil is activated, and the displacement efficiency is improved.


Molecules ◽  
2021 ◽  
Vol 26 (14) ◽  
pp. 4267
Author(s):  
Kuo-Hui Wu ◽  
Ryota Sakamoto ◽  
Hiroaki Maeda ◽  
Eunice Jia Han Phua ◽  
Hiroshi Nishihara

We developed an efficient and convenient electrochemical method to synthesize π-conjugated redox metal-complex linear polymer wires composed of azobenzene-bridged bis(terpyridine)metal (2-M, M = Fe, Ru) units covalently immobilized on glassy carbon (GC). Polymerization proceeds by electrochemical oxidation of bis(4′-(4-anilino)-2,2′:6′,2″-terpyridine)metal (1-M) in a water–acetonitrile–HClO4 solution, affording ultralong wires up to 7400 mers (corresponding to ca. 15 μm). Both 2-Fe and 2-Ru undergo reversible redox reactions, and their redox behaviors indicate remarkably fast redox conduction. Anisotropic hetero-metal-complex polymer wires with Fe and Ru centers are constructed via stepwise electropolymerization. The cyclic voltammograms of two hetero-metal-complex polymer wires, GC/[2-Fe]–[2-Ru] (3) and GC/[2-Ru]–[2-Fe] (4), show irreversible redox reactions with opposite electron transfer characteristics, indicating redox diodelike behavior. In short, the present electrochemical method is useful to synthesize polymer wire arrays and to integrate functional molecules on carbon.


Pharmaceutics ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 595
Author(s):  
Norraseth Kaeokhamloed ◽  
Emillie Roger ◽  
Jérôme Béjaud ◽  
Nolwenn Lautram ◽  
Florence Manero ◽  
...  

Standard models used for evaluating the absorption of nanoparticles like Caco-2 ignore the presence of vascular endothelium, which is a part of the intestinal multi-layered barrier structure. Therefore, a coculture between the Caco-2 epithelium and HMEC-1 (Human Microvascular Endothelial Cell type 1) on a Transwell® insert has been developed. The model has been validated for (a) membrane morphology by transmission electron microscope (TEM); (b) ZO-1 and β-catenin expression by immunoassay; (c) membrane integrity by trans-epithelial electrical resistance (TEER) measurement; and (d) apparent permeability of drugs from different biopharmaceutical classification system (BCS) classes. Lipid nanocapsules (LNCs) were formulated with different sizes (55 and 85 nm) and surface modifications (DSPE-mPEG (2000) and stearylamine). Nanocapsule integrity and particle concentration were monitored using the Förster resonance energy transfer (FRET) technique. The result showed that surface modification by DSPE-mPEG (2000) increased the absorption of 55-nm LNCs in the coculture model but not in the Caco-2. Summarily, the coculture model was validated as a tool for evaluating the intestinal absorption of drugs and nanoparticles. The new coculture model has a different LNCs absorption mechanism suggesting the importance of intestinal endothelium and reveals that the surface modification of LNCs can modify the in vitro oral absorption.


Fractals ◽  
2019 ◽  
Vol 27 (08) ◽  
pp. 1950142
Author(s):  
JINZE XU ◽  
KELIU WU ◽  
RAN LI ◽  
ZANDONG LI ◽  
JING LI ◽  
...  

Effect of nanoscale pore size distribution (PSD) on shale gas production is one of the challenges to be addressed by the industry. An improved approach to study multi-scale real gas transport in fractal shale rocks is proposed to bridge nanoscale PSD and gas filed production. This approach is well validated with field tests. Results indicate the gas production is underestimated without considering a nanoscale PSD. A PSD with a larger fractal dimension in pore size and variance yields a higher fraction of large pores; this leads to a better gas transport capacity; this is owing to a higher free gas transport ratio. A PSD with a smaller fractal dimension yields a lower cumulative gas production; this is because a smaller fractal dimension results in the reduction of gas transport efficiency. With an increase in the fractal dimension in pore size and variance, an apparent permeability-shifting effect is less obvious, and the sensitivity of this effect to a nanoscale PSD is also impaired. Higher fractal dimensions and variances result in higher cumulative gas production and a lower sensitivity of gas production to a nanoscale PSD, which is due to a better gas transport efficiency. The shale apparent permeability-shifting effect to nanoscale is more sensitive to a nanoscale PSD under a higher initial reservoir pressure, which makes gas production more sensitive to a nanoscale PSD. The findings of this study can help to better understand the influence of a nanoscale PSD on gas flow capacity and gas production.


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