scholarly journals The epidemic of 2019-novel-coronavirus (2019-nCoV) pneumonia and insights for emerging infectious diseases in the future

2020 ◽  
Vol 22 (2) ◽  
pp. 80-85 ◽  
Author(s):  
Jin-Yan Li ◽  
Zhi You ◽  
Qiong Wang ◽  
Zhi-Jian Zhou ◽  
Ye Qiu ◽  
...  
2020 ◽  
Vol 11 (SPL1) ◽  
pp. 86-93
Author(s):  
Dhirajsingh Sumersingh Rajput

Evolution is continuous process of changes in structural and physiological mechanism in living being. Microbes/pathogens can evolve naturally or artificially and become resistant to various medicines. Novel coronavirus is such evolved pathogen of coronavirus group. Enough strong immunity is needed to prevent or survive from COVID-19 pandemic. Ayurveda provides ways for evolving physiological responses to built immunity. Present work is brief attempt to increase insight in this filed.Present review was done based on simple theory of evolution, recent updates regarding prevention of COVID-19, Ayurveda aspect toward infectious diseases and Ayurveda ways towards prevention of infectious diseases with special reference to COVID-19. Person with impaired immunity is more susceptible for COVID-19 and thus immunity is an important preventing factor. Ayurveda Rasayana (rejuvanation) herbs, Yoga exercises, Pranayama (special breathing exercise), daily regimens and personal hygiene guidelines can be helpful strategies in controlling the spread of COVID-19.The preventive aspects of pandemic situations are narrated in Ayurveda with enough details. These ways need to be scientifically explored and refined for precision. As prevention is always better than cure hence Ayurveda ways can be considered for future strategies to avoid pandemics such as COVID-19.  There is great need of research on Ayurveda medicines on COVID-19 like diseases.


Author(s):  
Toni Wandra

World Health Organization (WHO) defines zoonotic diseases (zoonoses) as those diseases and infections which are naturally transmitted between vertebrate animals and humans. More than 250 zoonoses have been described, over 60% of pathogens that cause diseases in humans are zoonoses of animals, and 75% of emerging infectious diseases. Most pandemics are caused by zoonoses.


Author(s):  
Yoshihiro Yamahata ◽  
Ayako Shibata

BACKGROUND Japan implemented a large-scale quarantine on the Diamond Princess cruise ship in an attempt to control the spread of the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in February 2020. OBJECTIVE We aim to describe the medical activities initiated and difficulties in implementing quarantine on a cruise ship. METHODS Reverse transcription–polymerase chain reaction (RT-PCR) tests for SARS-CoV-2 were performed for all 3711 people (2666 passengers and 1045 crew) on board. RESULTS Of those tested, 696 (18.8%) tested positive for coronavirus disease (COVID-19), of which 410 (58.9%) were asymptomatic. We also confirmed that 54% of the asymptomatic patients with a positive RT-PCR result had lung opacities on chest computed tomography. There were many difficulties in implementing quarantine, such as creating a dividing traffic line between infectious and noninfectious passengers, finding hospitals and transportation providers willing to accept these patients, transporting individuals, language barriers, and supporting daily life. As of March 8, 2020, 31 patients (4.5% of patients with positive RT-PCR results) were hospitalized and required ventilator support or intensive care, and 7 patients (1.0% of patients with positive RT-PCR results) had died. CONCLUSIONS There were several difficulties in implementing large-scale quarantine and obtaining medical support on the cruise ship. In the future, we need to prepare for patients’ transfer and the admitting hospitals when disembarking the passengers. We recommend treating the crew the same way as the passengers to control the infection. We must also draw a plan for the future, to protect travelers and passengers from emerging infectious diseases on cruise ships.


Author(s):  
Jayakumar K ◽  
Aneen Suresh ◽  
Sony Peter

Infectious diseases continue to impose unpredictable burdens on global health and economies. Therefore, this has become a concern, even in terms of national security.  In this sense, the objective of the present article was to review the role of wild animals as reservoirs and/or dispersers of etiological agents of human infectious diseases in order to compile data on the main wild animals and etiological agents involved in zoonotic outbreaks. The zoonotic threat of these etiological agents and the impact on public health can be enormous as shown by the ongoing epidemic of 2019 novel coronavirus (2019- nCoV) infections. Keywords:  Infection, Emerging, Virus, Epedimiology, Pandemic, COVID


Author(s):  
Sebastián Campbell-Quintero ◽  
Santiago Campbell-Quintero ◽  
Santiago Campbell-Silva

Emerging infectious diseases, such as severe acute respiratory syndrome (SARS), present a major threat to public health. In December 2019, a novel coronavirus referred to as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as the causative agent of a respiratory syndrome named coronavirus disease 2019 (COVID-19). Since then, the pandemic has escalated. The spectrum of COVID-19 presentations ranges from mild self-limited flulike illness to severe viral pneumonia leading to acute respiratory distress syndrome that can be potentially fatal.


GigaScience ◽  
2020 ◽  
Vol 9 (8) ◽  
Author(s):  
Dima Kagan ◽  
Jacob Moran-Gilad ◽  
Michael Fire

Abstract Background COVID-19 is the most rapidly expanding coronavirus outbreak in the past 2 decades. To provide a swift response to a novel outbreak, prior knowledge from similar outbreaks is essential. Results Here, we study the volume of research conducted on previous coronavirus outbreaks, specifically SARS and MERS, relative to other infectious diseases by analyzing >35 million articles from the past 20 years. Our results demonstrate that previous coronavirus outbreaks have been understudied compared with other viruses. We also show that the research volume of emerging infectious diseases is very high after an outbreak and decreases drastically upon the containment of the disease. This can yield inadequate research and limited investment in gaining a full understanding of novel coronavirus management and prevention. Conclusions Independent of the outcome of the current COVID-19 outbreak, we believe that measures should be taken to encourage sustained research in the field.


Author(s):  
Ronghua Ding ◽  
Jinzhao Long ◽  
Mingzhu Yuan ◽  
Yuefei Jin ◽  
Haiyan Yang ◽  
...  

The continued global pandemic of coronavirus disease 2019 (COVID-19) poses a serious threat to global public health and social stability and it has become a serious global public health problem. Unfortunately, existing diagnostic and therapeutic approaches for the prevention and control of COVID-19 have many shortcomings. In recent years, the emerging CRISPR/Cas technology can complement the problems of traditional methods. Biological tools based on CRISPR/Cas systems have been widely used in biomedicine. In particular, they are advantageous in pathogen detection, clinical antiviral therapy, drug, and vaccine development. Therefore, CRISPR/Cas technology may have great potential for application in the prevention and control of COVID-19 and emerging infectious diseases in the future. This article summarizes the existing applications of CRISPR/Cas technology in infectious diseases with the aim of providing effective strategies for the prevention and control of COVID-19 and other emerging infectious diseases in the future.


2020 ◽  
Vol 03 (01) ◽  
pp. 1-9
Author(s):  
Zhen Gao ◽  
Linwei Lu ◽  
Qin Bian ◽  
Jinfeng Wu ◽  
Feng Liu ◽  
...  

Based on the naming of diseases in the history and the nomenclature of diseases, especially that of novel human infectious diseases, in traditional Chinese medicine (TCM) and modern medicine, we put forward the following suggestions for the naming and severity classification of “coronavirus disease 2019 (COVID-19)”: (1) Patients with only nucleic acids positive or nucleic acid positive as well as some of the symptoms but without any evidence of pneumonia should be diagnosed more generally such as “Novel coronavirus respiratory infection (NCRI)” or “Novel coronavirus infection (NCI)”. (2) The manifestations concerning pneumonia can be used as the main basis for the classification of the severity of the disease. For instance, those with only nucleic acids positive or nucleic acid positive as well as mild symptoms are mild, those with nucleic acid positive as well as symptoms like fever and cough are moderate, those with nucleic acid positive as well as pneumonia are severe, those with severe symptoms as well as respiratory failure and multiple organ damage are critical. (3) Also, those with infections and clinical manifestations but no pneumonia can be called simple type, and those with pneumonia can be called pneumonia type. (4) Under the current background of integrative medicine, the naming of newly emerging infectious diseases by TCM should be changed from an ambiguous concept to a clearly defined one. It may define the disease according to the etiology, pathogenesis, clinical manifestation or prognosis of the disease, redefine the original concept in TCM and discard the excessively broad part, or carry out the common naming between TCM and modern medicine based on the specific pathogen. (5) According to the nomenclature of diseases in TCM plus that in modern medicine, the NCI may be named “Jihai (2019) — Pestilence” (Ji Hài (2019) — Yì Lì) in TCM.


Author(s):  
Dima Kagan ◽  
Jacob Moran-Gilad ◽  
Michael Fire

AbstractCOVID-19 is the most rapidly expanding coronavirus outbreak in the past two decades. To provide a swift response to a novel outbreak, prior knowledge from similar outbreaks is essential. Here, we study the volume of research conducted on previous coronavirus outbreaks, specifically SARS and MERS, relative to other infectious diseases by analyzing over 35 million papers from the last 20 years. Our results demonstrate that previous coronavirus outbreaks have been understudied compared to other viruses. We also show that the research volume of emerging infectious diseases is very high after an outbreak and drops drastically upon the containment of the disease. This can yield inadequate research and limited investment in gaining a full understanding of novel coronavirus management and prevention. Independent of the outcome of the current COVID-19 outbreak, we believe that measures should be taken to encourage sustained research in the field.


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