T03-P-004 Family history of early cardiovascular disease: Diastolic blood pressure as a main target

2005 ◽  
Vol 6 (1) ◽  
pp. 147
Author(s):  
R. Fabregate ◽  
O. Sanchez ◽  
B. Monge ◽  
A. Ugalde ◽  
E. Fenandez ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Family History ◽  
Diastolic Blood Pressure ◽  
Main Target ◽  
History Of

scholarly journals A pilot study investigating the relationship between heart rate variability and blood pressure in young adults at risk for cardiovascular disease

2022 ◽  
Vol 28 (1) ◽  
Author(s):  
Linda P. Bolin ◽  
Amelia D. Saul ◽  
Lauren L. Bethune Scroggs ◽  
Carolyn Horne
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Pilot Study ◽  
Family History ◽  
Diastolic Blood Pressure ◽  
Biofeedback Training ◽  
Paced Breathing ◽  
History Of

Abstract Background Cardiovascular disease is one of the leading causes of death globally with hypertension being a primary cause of premature death from this disease process. Individuals with a family history of cardiovascular disease and hypertension are at a greater risk for developing the same sequela. Autonomic cardiac control is important in the level of cardiac function. One intervention that is effective in improving cardiovascular function is heart rate variability biofeedback training. The purpose of our study was to determine the effectiveness of heart rate biofeedback training on HRV and blood pressure in individuals with a family history of cardiovascular disease. Methods Thirty-four participants (76.5% female, 22.7 ± 4.3 years) completed a baseline assessment and training using an established short-term HRV protocol followed by two weeks of at-home paced breathing employing a smartphone application. The participants were then reassessed in a biofeedback clinic. Results The participants physiological measures showed a significant increase in means between pre and post intervention of SDNN (t (32) = 2.177, p =.037) and TP, (t (32) = 2.327 p = .026). Correlation noted a medium effect on diastolic blood pressure and high frequency heart rate variability, F, r = .41, n =33, p < .05. A multiple regression with all predictor variables in the model found no significance with diastolic and systolic blood pressure. Conclusions The findings from this pilot study demonstrated that a two-week paced breathing intervention may assist in reducing heart rate and diastolic blood pressure while improving heart rate variability.

Abstract P355: Predicting the 20-year Risk of First Coronary or Ischemic Stroke Event in Northern Italy: The CAMUNI Absolute Risk Equation

Circulation ◽  
2013 ◽  
Vol 127 (suppl_12) ◽  
Author(s):  
Giovanni Veronesi ◽  
Lloyd E Chambless ◽  
Francesco Gianfagna ◽  
Giuseppe Mancia ◽  
Giancarlo Cesana ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Family History ◽  
Diastolic Blood Pressure ◽  
Cardiovascular Events ◽  
Absolute Risk ◽  
Northern Italy ◽  
Men And Women ◽  
Basic Model ◽  
History Of

Aims. Recent US guidelines advocate the introduction of lifetime or long-term absolute risk prediction for primary prevention of cardiovascular events, especially for young people and women. Therefore, long-term prediction models might be specially beneficial in population considered at low incidence. We aim to develop a 20-year absolute risk prediction equation in a Northern Italy population. Methods. Four independent population-based cohorts were enrolled between 1986 and 1994 from the Brianza population (Northern Italy), adopting standardized MONICA procedures. The study sample comprises n=2574 men and 2673 women, aged 35 to 69 years and free of CVD at baseline. Participants were followed-up for incidence of first coronary and ischemic stroke events (fatal and non-fatal; all MONICA validated) for a median time of 15 years (IQ range: 12-20) and up to the end of 2008. We compared several gender-specific Cox Proportional Hazards models: the basic one includes age, total cholesterol, HDL-cholesterol, systolic blood pressure, anti-hypertensive treatment, cigarette smoking and diabetes. Candidates to model addition were diastolic blood pressure, triglycerides, BMI, family history of CHD, and education. Model calibration was tested using the Grønnesby-Bogan goodness-of-fit statistic. The Area Under the ROC-Curve (AUC) was a measure of discrimination, corrected for over-optimism via bootstrapping. Changes in discrimination (Δ-AUC) and reclassification (Net Reclassification Improvement, NRI) defined the improvement from the basic model due to an additional risk factor. Intermediate risk was defined as 20-year risk between 10% and 40%. Results. We observed n=286 events in men (incidence rate 7.7 per 1000 person-years) and n=108 in women (2.6 per 1000 person-years). All risk factors included in the basic model were predictive of first cardiovascular event in both genders; discrimination was 0.725 and 0.802 in men and women, respectively. Average specificity in the top risk quintile (cut-off value: 23% in men and 8.5% in women) was similar in men and women (85% vs. 83%), while sensitivity was higher in women (63% vs. 46%). All the models were well-calibrated (p-values >0.05). The addition of a positive family history of CHD in men (Hazard Ratio: 1.6; 95%CI 1.2-2.1) and of diastolic blood pressure in women (HR: 1.4 for 11 mmHg increase; 1.1-1.8) significantly improved discrimination (Δ-AUC=0.01; 95%CI 0.002-0.02 [men] and Δ-AUC=0.005; 95%CI 0.0001-0.01 [women]) and reclassification of subjects at intermediate risk (NRI=8.4%;1.7%-19.1% [men]; and NRI=11.7%; -3.2%-33.5% [women]). Conclusions. Traditional risk factors are predictive of cardiovascular events after 20 years, with good discrimination. The addition of family history of CHD may contribute to model improvement, at least among men; the role of diastolic blood pressure in women should be carefully evaluated.

scholarly journals Evaluation of blood pressure in school children aged 12-16 years

2017 ◽  
Vol 4 (4) ◽  
pp. 1218
Author(s):  
Balakrishnan Nadesan ◽  
Mani Madhavan Sachithananthamoorthi ◽  
Sivaraman Thirumalaikumarasamy ◽  
Ezhilarasu Ramalingam
Keyword(s):  
Blood Pressure ◽  
Family History ◽  
Diastolic Blood Pressure ◽  
School Children ◽  
Diastolic Pressure ◽  
Systolic Pressure ◽  
Cross Sectional ◽  
Significant Difference ◽  
History Of ◽  
Family History Of Hypertension

Background: Hypertension is considered as a major health issue in developed as well as developing countries and its possible origin during childhood prompts pediatricians to routinely include measurement of blood pressure (BP) as an integral part of pediatric physical examination. The objectives of the study were to evaluate the normal range of blood pressure in adolescent school going students of 12-16 years, prevalence of hypertension and relationship of BP with variables like age, body mass index (BMI), socioeconomic status and family history of hypertension.Methods: A cross sectional study was undertaken for a period of one year in adolescent school children in age groups between 12-16 years. Detailed clinical examination was done in 1060 adolescent school children and BP was recorded in right upper limb and correlation of BP with BMI, family history of hypertension and diabetes were studied.Results: Mean systolic and diastolic pressure showed linear relationship with age. There was a highly statistically significant difference between mean systolic and diastolic blood pressure between lower and middle socio-economic class. Prevalence of obesity in our study was 1.13%, overweight was 7.83%. Prevalence of hypertension in obese children was 33.33% and in overweight children 18.07%. Family history of hypertension and diabetes carry a significant correlation with elevated systolic and diastolic blood pressure in adolescents.Conclusions: This study revealed that socio economic factors play a significant role in determining the blood pressure of the individual. Children of middle class have significantly elevated mean systolic pressure and mean diastolic pressure than low socio-economic groups. 

scholarly journals Blood Pressure and Its Association with Gender, Body Mass Index, Smoking, and Family History among University Students

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Hussein H. Alhawari ◽  
Sameeha Al-Shelleh ◽  
Hussam H. Alhawari ◽  
Aseel Al-Saudi ◽  
Dina Aljbour Al-Majali ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Family History ◽  
Cardiovascular Diseases ◽  
University Students ◽  
Diastolic Blood Pressure ◽  
Body Mass ◽  
Mean Difference ◽  
Significant Difference ◽  
History Of

Hypertension is one of the major risk factors associated with cardiovascular diseases. In this study, we will assess the frequency of hypertension among healthy university students and its association with gender, body mass index, smoking, and family history of both hypertension and cardiovascular diseases. We screened healthy university students ranging from 18 to 26 years of age. For each participant, we performed blood pressure measurements using a previously validated device and obtained demographic data, body mass index (BMI), smoking status, and family history of both hypertension and cardiovascular diseases. Out of the total number of 505 participants included in this study, 35.2% have blood pressure between 130/80 and 139/89, and 13.5% have blood pressure of more than 140/90. We found significant gender differences in both systolic pressure (p = 0.003) with mean difference = 18.08 mmHg (CI: 16.13 to 19.9) and diastolic pressure (p = 0.011) with mean difference = 3.6 mmHg (CI: 2.06 to 5.14), higher in males than in females. Upon comparing the mean difference in both systolic and diastolic blood pressure with BMI, we found significant differences in both systolic (p < 0.001) and diastolic (p = 0.002) blood pressure. We also found that smokers have significantly (p = 0.025) higher systolic blood pressure (mean difference = 4.2 mmHg, CI: 3.2 mmHg to 8.8 mmHg), but no significant difference for diastolic blood pressure (p = 0.386), compared to nonsmokers. First-degree family history of both hypertension and cardiovascular diseases affected systolic but not diastolic blood pressure. Taking into account the adverse short- and long-term effect of hypertension, we recommend adopting an awareness program highlighting the importance of screening blood pressure in young adolescent populations, keeping in mind that both high BMI and smoking are important modifiable factors.

scholarly journals Family history of cardiovascular disease and non-HDL cholesterol in prepubescent non-obese children

2016 ◽  
Vol 62 (4) ◽  
pp. 347-352 ◽  
Author(s):  
Maria Wany Louzada Strufaldi ◽  
Fabíola Isabel Suano de Souza ◽  
Rosana Fiorini Puccini ◽  
Maria do Carmo Pinho Franco
Keyword(s):  
Risk Factors ◽  
Insulin Resistance ◽  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Family History ◽  
Hdl Cholesterol ◽  
Systemic Blood Pressure ◽  
Normal Body Mass Index ◽  
Cross Sectional ◽  
History Of

Summary Objective: To describe the values of non-HDL cholesterol (NHDL-c) and the frequency of a family history of early cardiovascular disease (family HCVD) in healthy prepubescent children. Analyze the association between NHDL-c and family HCVD, and possible associations with other risk factors for cardiovascular disease (CVD). Method: Cross-sectional study including 269 prepubescent (aged 6-10 years) schoolchildren with a normal body mass index (+1SD<BMI>-2SD). Data collected: Family HCVD; weight and height, waist circumference and systemic blood pressure; lipid profile (total cholesterol TC, HDL-c, triglycerides and LDL-c), NHDL-c calculation (CT-HDL-c, cut-off = 145 mg/dL) and insulin resistance (HOMA-IR). Results: High levels were found for NHDL-c in 10 (3.7%) of these schoolchildren, and family early HCVD was found in 46 (17.1%) of them. There was a weak association between family HCVD and NHDL-c (Cramer’s-V-test = 0.120; p=0.050). Among the children with NHDL-c≥145 mg/dL, 4 (40%) have family HCVD. The presence of family HCVD was not associated with the variables being studied. The variables independently associated with NHDL-c ≥ 145 mg/dL were: HOMA-IR (OR=1.7; 95CI 1.1-2.6) and diastolic blood pressure (OR=1.1; 95CI 1.02-1.2). Conclusion: NHDL-c values were associated with blood pressure and insulin resistance. Family HCVD was not associated with other classic risk factors for CVD, even though the frequency found was five times higher than that of high NHDL-c.

scholarly journals Effect of Acute Aerobic Exercise on Diastolic blood Pressure in Preclinical Medical Students of Services Institute of Medical Sciences, Lahore

Esculapio ◽  
2021 ◽  
Vol 17 (2) ◽  
pp. 170-174
Author(s):  
Muhammad Shafiq ◽  
◽  
Miraa Qutab ◽  
Saqib Javaid ◽  
Rida Fatima ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Medical Students ◽  
Family History ◽  
Aerobic Exercise ◽  
Diastolic Blood Pressure ◽  
Medical Sciences ◽  
Post Exercise ◽  
Waist Hip Ratio ◽  
History Of ◽  
Preclinical Medical Students

Objectives: To evaluate the response of acute bout of moderate exercise on DBP in preclinical medical students of Services Institute of Medical Sciences (SIMS), Lahore and to compare it with gender, family history, lifestyle and waist-hip-ratio of the study participants. Methods: This cross-sectional study was performed in the Department of Physiology, SIMS from May to December 2019. Ninety-three (93) healthy male and female MBBS students were recruited through nonprobability convenient sampling. Socio-demographic components were gathered using a ques-tionnaire. Anthropometric data (height, weight and waist-hip-ratio) and resting DBP was recorded before the exercise. All participants underwent exercise challenge on a treadmill. Post-exercise DBP was measured by taking serial recordings at zero minutes, 2 minutes and 5 minutes after exercise cessation. Data was analyzed using SPSSv20. Results: Within the 93 participants, 87(93.5%) were physically inactive, with only 6(6.5%) were physically active. In comparison with the baseline DBP, the DBP at zero and 2 minutes post exercise was statistically significant (p<0.001) in study participants. There was no significant correlation between DBP immediately after exercise and gender (p = 0.751); family history of hypertension and diabetes mellitus (p = 0.603); and lifestyle (p = 0.954). A non-significant (p = 0.636) yet positive correlation was observed between post exercise DBPand waist-hip-ratio among males. Conclusion: Our study revealed that an acute bout of exercise significantly raised the DBPimmediately after exercise. This rise in BP was not significantly related to gender, lifestyle and family history of diabetes mellitus and hypertension. Keywords: Diastolic blood pressure, aerobic exercise, waist-hip-ratio, medical students, treadmill How to cite: Shafiq M., Qutab M., Javaid S., Fatima R., Ijaz M., Shafiq A. Effect of acute aerobic exercise on diastolic blood pressure in preclinical medical students of Services Institute of Medical Sciences, Lahore. Esculapio 2021;17(02):170-174.

The prevalence and predictors of high blood pressure in Kherameh cohort study: a population based study on 10663 persons in south of Iran

2019 ◽  
Author(s):  
Fatemeh Jafari ◽  
Abbas Rezaianzadeh ◽  
Seyed Ebrahim Sadeghi ◽  
Salar Rahimikazerooni
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Risk Factor ◽  
Cohort Study ◽  
Family History ◽  
Urban Areas ◽  
High Body Mass Index ◽  
Family History Of Cancer ◽  
History Of ◽  
History Of Cancer

Abstract Background: Hypertension (HTN) is an important risk factor for Cardiovascular Disease (CVD) mortality and morbidity among Iranians. The present study aimed to estimate the prevalence of HTN and some of its related factors in south of Iran.Methods: This cross-sectional survey was conducted on the data of the Persian cohort study in Kherameh. The participants consisted of 10663 people aged 40-70 years. HTN was defined as either Systolic/Diastolic Blood Pressure (SBP/DBP) greater than or equal to 140/90 mmHg or taking medications. Pre-HTN was defined as SBP = 120-139 mmHg and/or DBP = 80-89 mmHg. The logistic regression method was used to identify the factors associated with pre-HTN and HTN.Results: The prevalence of pre-HTN and HTN was 18.8% and 27.7%, respectively. Male gender, old age, being unemployed, low education level, high Body Mass Index (BMI), no smoking, diabetes, Cerebro-cardiovascular disease, suffering from another chronic disease, family history of CVD, and negative family history of cancer and other chronic diseases were independently associated with pre-HTN (p<0.05). All variables, except for gender, smoking, and family history of cancer, were significantly associated with HTN. Drug abuse was also correlated to HTN (p<0.05).Conclusion: This study revealed the increased prevalence of HTN in rural and urban areas. Therefore, the health system needs to develop strategies to raise the accessibility of screening and diagnostic services. Keywords: Prevalence, Risk factor, Blood pressure, Pre-hypertension

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