scholarly journals Computational aerodynamics: Advances and challenges

2016 ◽  
Vol 120 (1223) ◽  
pp. 13-36 ◽  
Author(s):  
Dimitris Drikakis ◽  
Dochan Kwak ◽  
Cetin C. Kiris

ABSTRACTComputational aerodynamics, which complement more expensive empirical approaches, are critical for developing aerospace vehicles. During the past three decades, computational aerodynamics capability has improved remarkably, following advances in computer hardware and algorithm development. However, most of the fundamental computational capability realised in recent applications is derived from earlier advances, where specific gaps in solution procedures have been addressed only incrementally. The present article presents our view of the state of the art in computational aerodynamics and assessment of the issues that drive future aerodynamics and aerospace vehicle development. Requisite capabilities for perceived future needs are discussed, and associated grand challenge problems are presented.

Author(s):  
Volker Stein

The German discourse on Human Capital Management (HCM) has a long history which resulted in the manifoldness of notions connected with HCM. The exact specification of the meaning of HCM basically depends on the frame of reference used: the frame of the past, of the present or of the future. The present article which concentrates on the German aspects of the HCM debate is aimed at systematizing this discourse by outlining the past and present HCM development in Germany as well as its future perspectives. It will result in a synoptic view, summing up the German state-of-the-art HCM.


Author(s):  
Benno Liebchen ◽  
Aritra Kumar Mukhopadyay

Abstract The past two decades have seen a remarkable progress in the development of synthetic colloidal agents which are capable of creating directed motion in an unbiased environment at the microscale. These self-propelling particles are often praised for their enormous potential to self-organize into dynamic nonequilibrium structures such as living clusters, synchronized superrotor structures or self-propelling molecules featuring a complexity which is rarely found outside of the living world. However, the precise mechanisms underlying the formation and dynamics of many of these structures are still barely understood, which is likely to hinge on the gaps in our understanding of how active colloids interact. In particular, besides showing comparatively short-ranged interactions which are well known from passive colloids (Van der Waals, electrostatic etc.), active colloids show novel hydrodynamic interactions as well as phoretic and substrate-mediated “osmotic” cross-interactions which hinge on the action of the phoretic field gradients which are induced by the colloids on other colloids in the system. The present article discusses the complexity and the intriguing properties of these interactions which in general are long-ranged, non-instantaneous, nonpairwise and non-reciprocal and which may serve as key ingredients for the design of future nonequilibrium colloidal materials. Besides providing a brief overview on the state of the art of our understanding of these interactions a key aim of this review is to emphasize open key questions and corresponding open challenges.


2008 ◽  
Vol 1097 ◽  
Author(s):  
Isabelle Denry

AbstractThe evolution of dental ceramics over the past four decades has been remarkable in light of the increase in the diversity of materials and fabrication techniques that have become available. As a consequence, the applications and indications for all-ceramic materials continue to expand. The purpose of the present article is to review the evolution of dental ceramics from the various aspects of crystalline phases, glassy matrix, flaws and in vivo performance.


Author(s):  
Carl E. Henderson

Over the past few years it has become apparent in our multi-user facility that the computer system and software supplied in 1985 with our CAMECA CAMEBAX-MICRO electron microprobe analyzer has the greatest potential for improvement and updating of any component of the instrument. While the standard CAMECA software running on a DEC PDP-11/23+ computer under the RSX-11M operating system can perform almost any task required of the instrument, the commands are not always intuitive and can be difficult to remember for the casual user (of which our laboratory has many). Given the widespread and growing use of other microcomputers (such as PC’s and Macintoshes) by users of the microprobe, the PDP has become the “oddball” and has also fallen behind the state-of-the-art in terms of processing speed and disk storage capabilities. Upgrade paths within products available from DEC are considered to be too expensive for the benefits received. After using a Macintosh for other tasks in the laboratory, such as instrument use and billing records, word processing, and graphics display, its unique and “friendly” user interface suggested an easier-to-use system for computer control of the electron microprobe automation. Specifically a Macintosh IIx was chosen for its capacity for third-party add-on cards used in instrument control.


2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Xudong Zhu ◽  
Zhiyang Chen ◽  
Weiyan Shen ◽  
Gang Huang ◽  
John M. Sedivy ◽  
...  

AbstractRemarkable progress in ageing research has been achieved over the past decades. General perceptions and experimental evidence pinpoint that the decline of physical function often initiates by cell senescence and organ ageing. Epigenetic dynamics and immunometabolic reprogramming link to the alterations of cellular response to intrinsic and extrinsic stimuli, representing current hotspots as they not only (re-)shape the individual cell identity, but also involve in cell fate decision. This review focuses on the present findings and emerging concepts in epigenetic, inflammatory, and metabolic regulations and the consequences of the ageing process. Potential therapeutic interventions targeting cell senescence and regulatory mechanisms, using state-of-the-art techniques are also discussed.


2021 ◽  
Vol 26 (4) ◽  
Author(s):  
Mazen Mohamad ◽  
Jan-Philipp Steghöfer ◽  
Riccardo Scandariato

AbstractSecurity Assurance Cases (SAC) are a form of structured argumentation used to reason about the security properties of a system. After the successful adoption of assurance cases for safety, SAC are getting significant traction in recent years, especially in safety-critical industries (e.g., automotive), where there is an increasing pressure to be compliant with several security standards and regulations. Accordingly, research in the field of SAC has flourished in the past decade, with different approaches being investigated. In an effort to systematize this active field of research, we conducted a systematic literature review (SLR) of the existing academic studies on SAC. Our review resulted in an in-depth analysis and comparison of 51 papers. Our results indicate that, while there are numerous papers discussing the importance of SAC and their usage scenarios, the literature is still immature with respect to concrete support for practitioners on how to build and maintain a SAC. More importantly, even though some methodologies are available, their validation and tool support is still lacking.


Author(s):  
Fabricio Almeida-Silva ◽  
Kanhu C Moharana ◽  
Thiago M Venancio

Abstract In the past decade, over 3000 samples of soybean transcriptomic data have accumulated in public repositories. Here, we review the state of the art in soybean transcriptomics, highlighting the major microarray and RNA-seq studies that investigated soybean transcriptional programs in different tissues and conditions. Further, we propose approaches for integrating such big data using gene coexpression network and outline important web resources that may facilitate soybean data acquisition and analysis, contributing to the acceleration of soybean breeding and functional genomics research.


Open Theology ◽  
2016 ◽  
Vol 2 (1) ◽  
Author(s):  
Thomas G. Plante

AbstractSince the publication of Bergin’s classic 1980 paper “Psychotherapy and Religious Values” in the Journal of Clinical and Consulting Psychology, an enormous amount of quality research has been conducted on the integration of religious and spiritual values and perspectives into the psychotherapy endeavor. Numerous empirical studies, chapters, books, blogs, and specialty organizations have emerged in the past 35 years that have helped researchers and clinicians alike come to appreciate the value of religion and spirituality in the psychotherapeutic process. While so much has been accomplished in this area of integration, so much more needs to occur in order for the psychotherapeutic world to benefit from the wisdom of the great religious and spiritual traditions and values. While state-of-the-art quality research has and continues to demonstrate how religious and spiritual practices and values can be used effectively to enhance the benefits of behavioral and psychological interventions, too often the field either gets overly focused on particular and perhaps trendy areas of interest (e.g., mindfulness) or fails to appreciate and incorporate the research evidence supporting (or not supporting) the use of certain religiously or spiritually informed assessments and interventions. The purpose of this article is to reflect on where the field integrating religion, spirituality and psychotherapy has evolved through the present and where it still needs to go in the future. In doing so I hope to reflect on the call for integration that Bergin highlights in his classic 1980 paper.


Erdkunde ◽  
2021 ◽  
Vol 75 (2) ◽  
pp. 87-104
Author(s):  
Nicola Di Cosmo ◽  
Sebastian Wagner ◽  
Ulf Büntgen

After a successful conquest of large parts of Syria in 1258 and 1259 CE, the Mongol army lost the battle of 'Ayn Jālūt against Mamluks on September 3, 1260 CE. Recognized as a turning point in world history, their sudden defeat triggered the reconfiguration of strategic alliances and geopolitical power not only in the Middle East, but also across much of Eurasia. Despite decades of research, scholars have not yet reached consensus over the causes of the Mongol reverse. Here, we revisit previous arguments in light of climate and environmental changes in the aftermath of one the largest volcanic forcings in the past 2500 years, the Samalas eruption ~1257 CE. Regional tree ring-based climate reconstructions and state-of-the-art Earth System Model simulations reveal cooler and wetter conditions from spring 1258 to autumn 1259 CE for the eastern Mediterranean/Arabian region. We therefore hypothesize that the post-Samalas climate anomaly and associated environmental variability affected an estimated 120,000 Mongol soldiers and up to half a million of their horses during the conquest. More specifically, we argue that colder and wetter climates in 1258 and 1259 CE, while complicating and slowing the campaign in certain areas, such as the mountainous regions in the Caucasus and Anatolia, also facilitated the assault on Syria between January and March 1260. A return to warmer and dryer conditions in the summer of 1260 CE, however, likely reduced the regional carrying capacity and may therefore have forced a mass withdrawal of the Mongols from the region that contributed to the Mamluks’ victory. In pointing to a distinct environmental dependency of the Mongols, we offer a new explanation of their defeat at 'Ayn Jālūt, which effectively halted the further expansion of the largest ever land-based empire.


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