Heavy metals as pollutants in the working and living environment are a
serious health and environmental problem because they are toxic,
non-biodegradable, accumulate in living systems and have a long half-life in
soil. Sources of lead contamination are combustion products in the chemical
industry and metallurgy, industrial waste water, landfills, traffic etc. Lead
enters into the body via the food chain and drinking water. In the body lead
is deposited in the liver, kidneys, brain and mineral tissues. Excretion of
lead causes damage to the epithelial cells of certain organs. High level
exposure to cadmium is usually the result of environmental pollution by human
activities. Exposure to cadmium can lead to acute and chronic tissue damage
of various organs, including liver and kidneys in humans and in animals. In
this paper we analyzed the effects of lead and cadmium exposure, in working
and living environment, on the model system of experimental animals,
particularly the activity of certain liver enzymes, acid and alkaline DNase,
and standard biochemical blood parameters. The study showed that lead and
cadmium significantly affect the protein content, red blood cells, hemoglobin
and hematocrit, and the activity of liver enzymes. This harmful effect of
this toxic metal can be reduced by the supplements.