Philosophy

2013 ◽  
Vol 60 (2) ◽  
pp. 341-358
Author(s):  
Luca Castagnoli

The interest in Presocratic philosophy, and the scholarly output on it, have been rising again in the last few years. I start this review with a sample of recent publications in the area. It is easy to expect that Daniel Graham's collection of The Texts of Early Greek Philosophy, in two volumes, will become a popular tool for the study of Presocratic philosophy (for some qualifications on this expectation see below). The sourcebook aims to present ‘the complete fragments and a generous selection of testimonies’ for the major early Greek philosophers. English translations (all by Graham himself) are set opposite to Greek and Latin texts (with slim textual notes identifying substantive textual variants), with succinct introductions for each philosopher, and brief commentaries and basic bibliographies following the texts. The Diels-Kranz (hereafter DK) collection is the starting point for this sourcebook, but Graham is quite selective in his shortlist of those who deserve a place in his sourcebook: out of ninety DK sections, he includes only nineteen philosophers (Thales, Anaximander, Anaximenes, Xenophanes, Heraclitus, Parmenides, Zeno of Elea, Anaxagoras, Empedocles, Diogenes of Apollonia, Melissus, Philolaus, Leucippus, Democritus, Protagoras, Gorgias, Antiphon, Prodicus, and Pythagoras, the last being relegated to an appendix) and two anonymous texts, the Anonymus Iamblichi and the Dissoi Logoi. Although the sourcebook includes some fragments and testimonies that did not appear in DK (e.g. the Strasbourg papyrus for Empedocles), and only a selection of the testimonies included there, the major difference in terms of the material included for the selected philosophers is the order in which fragments and testimonies are presented. The fragments are incorporated within the context of the broader testimonies containing them (and signalled in bold), rather than listed separately, as in DK; the numbering of fragments and testimonies does not correspond to DK, but the DK numbers are given in addition, and volume 2 includes a list of concordances (besides an index of sources, an index of other passages quoted by Graham in his end-of-chapter commentaries, and a short general index of names and topics). Graham's choice is definitely a healthy step forward from DK's largely artificial strategy of separating fragments and testimonies into two different sections; one might wonder whether the decision to signal in bold words, phrases, sentences, and sections that supposedly count as original fragments within the broader context in which they occur is still too heavily indebted to the DK model. For each author the texts are organized in four main sections: life, works, philosophy, and reception, with the philosophy section typically structured into thematic subsections. Of course the strengths and shortcomings of a monumental work such as Graham's can be fully appreciated only over time, once you use it repeatedly in your teaching and research. I have mentioned Graham's approach to the distinction between fragments and testimonies: some sustained methodological discussion, and explanation of the criteria guiding the distinction, would have been welcome. Unavoidably some readers will find Graham's shortlist of philosophers and selection of texts unsatisfactory and too narrow: some qualms about notable exclusions – such as Solon, Alcmaeon, Archytas, Pherecydes, the Orphics, and the Derveni author – have already been voiced (for example, by Jason Rheins in his review in Notre Dame Philosophical Reviews). As far as I could see, the translations are reliable, and the short introductions, commentaries, and bibliographies provide just enough information for readers to contextualize the authors and texts within the philosophical tradition (less so within the broader archaic Greek cultural and literary tradition), and appreciate some of the key exegetical and philosophical issues that they raise. Just enough, and this brings me to what I find to be the less convincing aspect of such an enterprise as Graham's. His collection will certainly be of some use as an accessible reference tool for advanced students and researchers, but its selectivity will prevent it from becoming a research tool in its own right, and standard editions of individual Presocratics will remain the first port of call (for example, the second edition of Coxon's The Fragments of Parmenides, reviewed below). At the same time, the breadth of the material that it contains, coupled with the relative thinness of the apparatus of introductions and commentaries, does not make The Texts of Early Greek Philosophy the kind of introductory sourcebook that could be used on its own in an introductory undergraduate course on ancient philosophy, or on the Presocratics. It is difficult to imagine lecturers of such courses prescribing to their students more than a small fraction of the material offered by Graham; and those students will still need to use standard introductions to Presocratic philosophy such as Kirk–Raven–Schofield, Barnes, McKirahan, or Warren to make real sense of the evidence presented by Graham, placing it within a unified narrative about the nature and development of early Greek philosophy. From this point of view, Graham's collection risks falling into no man's land from the point of view of its readership: it is neither a ground-breaking, research-shaping tool such as, for example, Long and Sedley's collection on The Hellenistic Philosophers has been for three decades now, nor an introductory textbook easily accessible (for both sheer bulk and price) to undergraduate students. That said, Graham's work still deserves a place in all university libraries and on the shelves of ancient philosophy scholars.

2020 ◽  
Vol 16 (6) ◽  
pp. 784-795
Author(s):  
Krisnna M.A. Alves ◽  
Fábio José Bonfim Cardoso ◽  
Kathia M. Honorio ◽  
Fábio A. de Molfetta

Background:: Leishmaniosis is a neglected tropical disease and glyceraldehyde 3- phosphate dehydrogenase (GAPDH) is a key enzyme in the design of new drugs to fight this disease. Objective:: The present study aimed to evaluate potential inhibitors of GAPDH enzyme found in Leishmania mexicana (L. mexicana). Methods: A search for novel antileishmanial molecules was carried out based on similarities from the pharmacophoric point of view related to the binding site of the crystallographic enzyme using the ZINCPharmer server. The molecules selected in this screening were subjected to molecular docking and molecular dynamics simulations. Results:: Consensual analysis of the docking energy values was performed, resulting in the selection of ten compounds. These ligand-receptor complexes were visually inspected in order to analyze the main interactions and subjected to toxicophoric evaluation, culminating in the selection of three compounds, which were subsequently submitted to molecular dynamics simulations. The docking results showed that the selected compounds interacted with GAPDH from L. mexicana, especially by hydrogen bonds with Cys166, Arg249, His194, Thr167, and Thr226. From the results obtained from molecular dynamics, it was observed that one of the loop regions, corresponding to the residues 195-222, can be related to the fitting of the substrate at the binding site, assisting in the positioning and the molecular recognition via residues responsible for the catalytic activity. Conclusion:: he use of molecular modeling techniques enabled the identification of promising compounds as inhibitors of the GAPDH enzyme from L. mexicana, and the results obtained here can serve as a starting point to design new and more effective compounds than those currently available.


2021 ◽  
pp. 44-54
Author(s):  
Michael Frede

This chapter evaluates the historical history of philosophy. Given the very strong philosophical assumptions underlying the early philosophical histories of philosophy, and given in particular the fact that they tended to be written from the point of view of some kind of idealism, it is not surprising that they should have met with some resistance, in particular outside philosophy. Thus, one finds Albert Schwegler criticizing Hegel’s method of treating the history of philosophy, rejecting any kind of philosophical history of philosophy as history. He insists that the systematical study of the history of philosophy is the task of a historian and has to be pursued in precisely the way one studies any other kind of history or history in general. Zeller therefore advocates a purely historical approach to the history of philosophy, a historian’s history of philosophy, and his own monumental work on the history of Greek philosophy is inspired by this conception, just as it, in turn, inspires a lot of work, at least on ancient philosophy of the same kind. The chapter then presents a systematical consideration of the historical history of philosophy.


Entropy ◽  
2020 ◽  
Vol 22 (10) ◽  
pp. 1148
Author(s):  
Michał Cieśla ◽  
Małgorzata Snarska

We study mechanisms leading to wealth condensation. As a natural starting point, our model adopts a neoclassical point of view, i.e., we completely ignore work, production, and productive relations, and focus only on bilateral link between two randomly selected agents. We propose a simple matching process with deterministic trading rules and random selection of trading agents. Furthermore, we also neglect the internal characteristic of traded goods and analyse only the relative wealth changes of each agent. This is often the case in financial markets, where a traded good is money itself in various forms and various maturities. We assume that agents trade according to the rules of utility and decision theories. Agents possess incomplete knowledge about market conditions, but the market is in equilibrium. We show that these relatively frugal assumptions naturally lead to a wealth condensation. Moreover, we discuss the role of wealth redistribution in such a model.


2019 ◽  
Vol 16 (2-3) ◽  
pp. 161-179
Author(s):  
Outi Paloposki

The article looks at book production and circulation from the point of view of translators, who, as purchasers and readers of foreign-language books, are an important mediating force in the selection of literature for translation. Taking the German publisher Tauchnitz's series ‘Collection of British Authors’ and its circulation in Finland in the nineteenth and early twentieth century as a case in point, the article argues that the increased availability of English-language books facilitated the acquiring and honing of translators' language skills and gradually diminished the need for indirect translating. Book history and translation studies meet here in an examination of the role of the Collection in Finnish translators' work.


2020 ◽  
Vol 7 (2) ◽  
pp. 34-41
Author(s):  
VLADIMIR NIKONOV ◽  
◽  
ANTON ZOBOV ◽  

The construction and selection of a suitable bijective function, that is, substitution, is now becoming an important applied task, particularly for building block encryption systems. Many articles have suggested using different approaches to determining the quality of substitution, but most of them are highly computationally complex. The solution of this problem will significantly expand the range of methods for constructing and analyzing scheme in information protection systems. The purpose of research is to find easily measurable characteristics of substitutions, allowing to evaluate their quality, and also measures of the proximity of a particular substitutions to a random one, or its distance from it. For this purpose, several characteristics were proposed in this work: difference and polynomial, and their mathematical expectation was found, as well as variance for the difference characteristic. This allows us to make a conclusion about its quality by comparing the result of calculating the characteristic for a particular substitution with the calculated mathematical expectation. From a computational point of view, the thesises of the article are of exceptional interest due to the simplicity of the algorithm for quantifying the quality of bijective function substitutions. By its nature, the operation of calculating the difference characteristic carries out a simple summation of integer terms in a fixed and small range. Such an operation, both in the modern and in the prospective element base, is embedded in the logic of a wide range of functional elements, especially when implementing computational actions in the optical range, or on other carriers related to the field of nanotechnology.


Trictrac ◽  
2016 ◽  
Vol 9 ◽  
Author(s):  
Liliana Danciu ◽  
Petru Adrian Danciu

The axes of the creation and birth of the imaginary as a mythical language. Our research follows the relationships of the concepts that are taking into account creation on the double axis of verticality and horizontality. We highlight those symbolic elements which would later constitute the mythical language about the sacred space-temporality. Inside this space-temporality a rich spectrum of mythical images develops; images capable of explaining the relationships of the creation plans. Without a religious perception of the temporality, the conceptualization of the axis would remain a philosophical approach. Through our point of view, the two are born simultaneously. Thanks to them, creation can be imagined. The first “frozen” formula of the mystical human spirit can be thought, brought to a palpable reality, expressed in an oral and then a written form. Studied together, temporality (sacred or not) and space are permanently imagined together. For example, a loss of mundane temporality in the secret ecstasy that offers to the soul an ascending direction does not mean getting out of universal temporality, but of its mundane section. In the sacred space the soul relates to time. Even the gods are submitted by the sacred, Aeon sometimes being synonymous to destiny. The universal creator seems to evade every touch, but not consistently, only when he avoids the descent into its created worlds. In sacredness, time and space seem or become confused, both expressing the same reality, by the immediate swing from thinking to deed. The mythical imagery conceives the displacement in the primary space-temporality by the spoken word. So, for something to appear and live, the spoken word is required. Even the divine dream appears as a pre-word of a creator’s thought. The thought follows the spoken word, the spoken word follows the gestures which finally indicate the meanings of the creative act, controlling the rhythm of the creation days. These three will later be adapted through imitation in rite. We are now situated at the limit of the physical world, a real challenge for the mythical imagery. The general feature of the mythical expression on the creation of the material world is the state of the divinity’s exhaustion, most often conceptualized by sacrifice or divine fatigue. The world geography identifies with the anatomy of a self-gutted god. Practically, material creation is most likely the complete revelation of God’s body autopsy. As each body decomposes, everything in it is an illusion. An axial approach of the phenomenon exists in all religious systems. The created element’s origin is exterior, with or without a pre-existing matter, by a god’s sacrifice or only because it has to be that way. This is the starting point of the discussion on the symbolism of axiality as a reason for the constitution of the language of creation, capable of retelling the imaginary construction of myth in an oral and then written form.


2019 ◽  
Vol 62 (6) ◽  
pp. 126-137
Author(s):  
Tatyana G. Korneeva

The article discusses the problem of the formation of philosophical prose in the Persian language. The first section presents a brief excursion into the history of philosophical prose in Persian and the stages of formation of modern Persian as a language of science and philosophy. In the Arab-Muslim philosophical tradition, representatives of various schools and trends contributed to the development of philosophical terminology in Farsi. The author dwells on the works of such philosophers as Ibn Sīnā, Nāṣir Khusraw, Naṣīr al-Dīn al-Ṭūsī, Aḥmad al-Ghazālī, ʼAbū Ḥāmid al-Ghazālī and gives an overview of their works written in Persian. The second section poses the question whether the Persian language proved able to compete with the Arabic language in the field of science. The author examines the style of philosophical prose in Farsi, considering the causes of creation of Persian-language philosophical texts and defining their target audience. The article presents viewpoints of modern orientalist researchers as well as the views of medieval philosophers who wrote in Persian. We find that most philosophical texts in Persian were written for a public who had little or no knowledge of the Arabic language, yet wanted to get acquainted with current philosophical and religious doctrines, albeit in an abbreviated format. The conclusion summarizes and presents two positions regarding the necessity of writing philosophical prose in Persian. According to one point of view, Persian-language philosophical works helped people who did not speak Arabic to get acquainted with the concepts and views of contemporary philosophy. According to an alternative view, there was no special need to compose philosophical texts in Persian, because the corpus of Arabic philosophical terminology had already been formed, and these Arabic terms were widely and successfully used, while the new Persian philosophical vocabulary was difficult to understand.


2020 ◽  
pp. 123-150
Author(s):  
Julia Saviello

Smell and taste – of the five senses these are the two most strongly stimulated by smoking tobacco. The article presents an in-depth analysis of the reflection of both these forms of sensory perception in textual and visual sources concerning the early consumption of the herb. In a first step, tobacco’s changing reception, first as medicine and then as stimulant, is traced through the years of its increasing distribution in Europe, starting in the middle of the 16th century. As this overview reveals, at that time the still little known substance gave rise to new forms of sense perception. Following recent studies on smell and gustation, which have stressed the need to take into account the interactions between these senses, the article probes the manifold stimulation of the senses by tobacco with reference to allegorical representations and genre scenes addressing the five senses. The smoking of tobacco was thematized in both of these art forms as a means of visualizing either smell or taste. Yet, these depictions show no indication of any deliberate engagement with the exchange of sense data between mouth and nose. The question posed at the end of this paper is whether this holds true also for early smoker’s still lifes. In the so-called toebakjes or rookertjes, a subgenre of stilllife painting that, like tobacco, was still a novelty at the beginning of the 17th century, various smoking paraphernalia – such as rolled or cut tobacco, pipes and tins – are arrayed with various kinds of foods and drinks. Finally, the article addresses a selection of such smoker’s still lifes, using the toebakje by Pieter Claesz., probably the first of its kind, as a starting point and the work by Georg Flegel as a comparative example. Through their selection of objects, both offer a complex image of how tobacco engages different senses.


2012 ◽  
pp. 66-80
Author(s):  
Michał Mrozowicki

Michel Butor, born in 1926, one of the leaders of the French New Novel movement, has written only four novels between 1954 and 1960. The most famous of them is La Modification (Second thoughts), published in 1957. The author of the paper analyzes two other Butor’s novels: L’Emploi du temps (Passing time) – 1956, and Degrés (Degrees) – 1960. The theme of absence is crucial in both of them. In the former, the novel, presented as the diary of Jacques Revel, a young Frenchman spending a year in Bleston (a fictitious English city vaguely similar to Manchester), describes the narrator’s struggle to survive in a double – spatial and temporal – labyrinth. The first of them, formed by Bleston’s streets, squares and parks, is symbolized by the City plan. During his one year sojourn in the city, using its plan, Revel learns patiently how to move in its different districts, and in its strange labyrinth – strange because devoid any centre – that at the end stops annoying him. The other, the temporal one, symbolized by the diary itself, the labyrinth of the human memory, discovered by the narrator rather lately, somewhere in the middle of the year passed in Bleston, becomes, by contrast, more and more dense and complex, which is reflected by an increasinly complex narration used to describe the past. However, at the moment Revel is leaving the city, he is still unable to recall and to describe the events of the 29th of February 1952. This gap, this absence, symbolizes his defeat as the narrator, and, in the same time, the human memory’s limits. In Degrees temporal and spatial structures are also very important. This time round, however, the problems of the narration itself, become predominant. Considered from this point of view, the novel announces Gerard Genette’s work Narrative Discourse and his theoretical discussion of two narratological categories: narrative voice and narrative mode. Having transgressed his narrative competences, Pierre Vernier, the narrator of the first and the second parts of the novel, who, taking as a starting point, a complete account of one hour at school, tries to describe the whole world and various aspects of the human civilization for the benefit of his nephew, Pierre Eller, must fail and disappear, as the narrator, from the third part, which is narrated by another narrator, less audacious and more credible.


2004 ◽  
Vol 155 (5) ◽  
pp. 142-145 ◽  
Author(s):  
Claudio Defila

The record-breaking heatwave of 2003 also had an impact on the vegetation in Switzerland. To examine its influences seven phenological late spring and summer phases were evaluated together with six phases in the autumn from a selection of stations. 30% of the 122 chosen phenological time series in late spring and summer phases set a new record (earliest arrival). The proportion of very early arrivals is very high and the mean deviation from the norm is between 10 and 20 days. The situation was less extreme in autumn, where 20% of the 103 time series chosen set a new record. The majority of the phenological arrivals were found in the class «normal» but the class«very early» is still well represented. The mean precocity lies between five and twenty days. As far as the leaf shedding of the beech is concerned, there was even a slight delay of around six days. The evaluation serves to show that the heatwave of 2003 strongly influenced the phenological events of summer and spring.


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