Frequency and heritability of depression symptomatology in the second half of life: evidence from Danish twins over 45

2002 ◽  
Vol 32 (7) ◽  
pp. 1175-1185 ◽  
Author(s):  
W. JOHNSON ◽  
M. McGUE ◽  
D. GAIST ◽  
J. W. VAUPEL ◽  
K. CHRISTENSEN
Keyword(s):  
Depressive Symptoms ◽  
Age Groups ◽  
Well Being ◽  
The Elderly ◽  
Depression Symptoms ◽  
Same Sex ◽  
Symptoms Of Depression ◽  
Genetic Origins ◽  
Depression Symptomatology ◽  
Special Risk

Background. Self-reported depressive symptoms among the elderly have generated considerable interest because they are readily available measures of overall well-being in a population often thought to be at special risk for mental disorder.Method. The heritability of depression symptoms was investigated in a sample of 2169 pairs of Danish twins (1033 MZ and 1136 same sex DZ) ranging in age from 45 to over 95. Twins completed an interview assessment that identified symptoms of depression, which were scored on Affective, Somatic and Total scales.Results. Overall heritability estimates (a2) for the Affective (a2 = 0.27, (95% CI 0.22–0.32)). Somatic (a2 = 0.26, (0.21–0.32)), and Total (a2 = 0.29, (0.22–0.34)) scales were all moderate, statistically significant and similar to results from other studies. To assess possible variations in heritability across the wide age span, the sample was stratified into age groups in increments of 10 years. The magnitude of heritable influence did not vary significantly with age or sex. Somatic scale heritability tended to be greater for females than for males, though this difference was not statistically significant. The genetic correlation between the Affective and Somatic scales was 0.71, suggesting substantial common genetic origins.Conclusions. Though the frequency of self-reported depressive symptoms increased with age in this sample, their heritability did not.

Examining the Temporal Dynamics of Anxiety and Depressive Symptoms During a Therapist-Supported, Smartphone-Based Intervention for Major Depression (Preprint)

2020 ◽  
Author(s):  
Santiago Allende ◽  
Valerie Forman-Hoffman ◽  
Philippe Goldin
Keyword(s):  
Depressive Symptoms ◽  
Temporal Relationship ◽  
Temporal Dynamics ◽  
Digital Health ◽  
Quadratic Function ◽  
Depression Symptoms ◽  
Symptoms Of Depression ◽  
Effect Model ◽  
End Of Treatment ◽  
Highly Correlated

UNSTRUCTURED Background: Anxiety and depression symptoms are highly correlated in adults with depression; however, little is known about their interaction and temporal dynamics of change during treatment. Thus, the primary aim of this study was to examine the temporal dynamics of anxiety and depressive symptoms during a 12-week therapist-supported, smartphone-delivered digital health intervention for symptoms of depression and anxiety, the Meru Health Program (MHP). Method: A total of 290 participants from the MHP were included in the present analyses (age Mean = 39.64, SD = 10.25 years; 79% female; 54% self-reported psychotropic medication use). A variance components model was used to examine whether (1) reporting greater anxiety during the current week relative to anxiety reported in other weeks would be associated with greater reporting of depressive symptoms during the current week, while a time-varying effect model was used to examine whether, (2) consistent with findings reported by Wright et al. (2014), the temporal relationship between anxiety and depressive symptoms during the intervention would be expressed as a quadratic function marked by a weak association at baseline, followed by an increase to a peak before demonstrating a negligible decrease until the end of treatment. Results: In support of hypothesis 1, we found that reporting greater anxiety symptoms during the current week relative to other weeks was associated with greater depressive symptoms during the current week. Contrary to hypothesis 2, the temporal relationship between anxiety and depressive symptoms evidenced a recurring pattern, with the association increasing during the initial weeks, decreasing during mid-treatment and sharply increasing toward the end of treatment. Conclusions: The present findings demonstrate that anxiety and depressive symptoms overlap and fluctuate in concert during a smartphone-based intervention for anxiety and depressive symptoms. The present findings may warrant more refined intervention strategies specifically tailored to co-occurring patterns of change in symptoms.

scholarly journals Exploring the Frequency of Anxiety and Depression Symptoms in a Brazilian Sample during the COVID-19 Outbreak

2021 ◽  
Vol 18 (9) ◽  
pp. 4847
Author(s):  
Fabiana Silva Ribeiro ◽  
Flávia H. Santos ◽  
Luis Anunciação ◽  
Lucas Barrozo ◽  
Jesus Landeira-Fernandez ◽  
...  
Keyword(s):  
Mental Health Professionals ◽  
Online Survey ◽  
Age Groups ◽  
Health Sector ◽  
Severe Depression ◽  
Well Being ◽  
Sociodemographic Factors ◽  
Anxiety And Depression ◽  
Depression Symptoms ◽  
Brazilian Sample

The COVID-19 pandemic is a public health emergency of international concern, and the main measures to contain the spread of the coronavirus causing COVID-19 were social distancing, quarantine, and self-isolation. Although these policies are effective in containing the spread of the virus, they might represent a challenge to psychological well-being, increasing levels of depressive and anxiety-related symptoms. Aims: We explored the frequency of anxiety and depression symptoms during COVID-19 restrictions and associations with sociodemographic factors in a Brazilian sample. Method: Data of a total of 936 Brazilian adults (68.2% women) aged 18 to 77 years old (M = 38.95, SD = 13.91) were collected through an online survey. Results: In general, we observed a frequency of 17.36% for severe anxiety and 66.13% for severe depression symptoms, in which younger participants (18–39 years old) and women showed higher scores in anxiety and depression scales compared to older age groups. Logistic regressions showed that women were more likely to present severe symptoms of anxiety (20.4%) compared to men (10.9%), as well as respondents in the educational sector (24.3%) compared to those in the health sector (10%). Conclusions: We highlight the importance of mental health professionals in developing strategies to help younger adults to mitigate the effects of social restriction.

scholarly journals Depressive Symptoms and Associated Factors in Female Students in Fukushima Four Years after the Fukushima Nuclear Power Plant Disaster

2018 ◽  
Vol 15 (11) ◽  
pp. 2411 ◽  
Author(s):  
Shinya Ito ◽  
Mie Sasaki ◽  
Satoko Okabe ◽  
Nobuhiro Konno ◽  
Aya Goto
Keyword(s):  
Depressive Symptoms ◽  
Risk Perceptions ◽  
Radiation Risk ◽  
Well Being ◽  
Female Students ◽  
World Health ◽  
Nuclear Radiation ◽  
Depression Symptoms ◽  
Cross Sectional Survey ◽  
Cross Sectional

Young women in their late teens and early 20s are at the highest risk for depression onset. The present study aimed to assess depressive symptoms among female college students in Fukushima. More specifically, it aimed to clarify factors predicting possible symptom profiles, with an emphasis on determining how nuclear radiation risks affect the reporting of depression symptoms. A cross-sectional survey was conducted of 310 female students at a college in the Fukushima prefecture, Japan, in December 2015, and 288 participants submitted valid questionnaires. In total, 222 (77.1%) participants lived in Fukushima at the time of the Great East Japan Earthquake. The measures included the World Health Organization-Five Well-Being Index, the Fukushima Future Parents Attitude Measure, and risk perception of radiation health effects. A total of 46.5% of participants reported depressive symptoms. Path analysis revealed that higher radiation risk perceptions and reduced efficacy with reproduction related to a decline in self-esteem and self-efficacy, which was subsequently associated with increased depressive symptoms. These findings highlight the importance of radiation education among children and young adults, both after a nuclear accident and during disaster preparation, particularly in the context of reproductive and mental health.

scholarly journals Family functioning of elderly with depressive symptoms

2014 ◽  
Vol 48 (3) ◽  
pp. 469-476 ◽  
Author(s):  
Rosely Almeida Souza ◽  
Gislaine Desani da Costa ◽  
Cintia Hitomi Yamashita ◽  
Fernanda Amendola ◽  
Jaqueline Correa Gaspar ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Family Functioning ◽  
Family Health ◽  
Female Gender ◽  
Well Being ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Dysfunctional Family ◽  
The Family

Objective: To classify families of elderly with depressive symptoms regarding their functioning and to ascertain the presence of an association between these symptoms, family functioning and the characteristics of the elderly. Method: This was an observational, analytical, cross-sectional study performed with 33 teams of the Family Health Strategy in Dourados, MS. The sample consisted of 374 elderly divided into two groups (with and without depressive symptoms). The instruments for data collection were a sociodemographic instrument, the GeriatricDepression Scale (15 items) and the Family Apgar. Results: An association was observed between depressive symptoms and family dysfunction, female gender, four or more people living together, and physical inactivity. Conclusion: The functional family may represent effective support for the elderly with depressive symptoms, because it offers a comfortable environment that ensures the well-being of its members. The dysfunctional family can barely provide necessary care for the elderly, which can exacerbate depressive symptoms.


scholarly journals The reliability and validity of the Patient Health Questionnaire-9 (PHQ-9) and PHQ-2 in patients with infertility

2019 ◽  
Vol 16 (1) ◽  
Author(s):  
Saman Maroufizadeh ◽  
Reza Omani-Samani ◽  
Amir Almasi-Hashiani ◽  
Payam Amini ◽  
Mahdi Sepidarkish
Keyword(s):  
Depressive Symptoms ◽  
Internal Consistency ◽  
Convergent Validity ◽  
Univariate Analysis ◽  
Reliability And Validity ◽  
Well Being ◽  
Patient Health Questionnaire ◽  
Depression Symptoms ◽  
Health Questionnaire ◽  
Patient Health

Abstract Background Depression in patients with infertility often goes undiagnosed and untreated. The Patient Health Questionnaire-9 (PHQ-9) and its ultra-brief version (i.e. PHQ-2) are widely used measures of depressive symptoms. These scales have not been validated in patients with infertility. The aim of the present study was to examine the reliability and validity of the PHQ-9 and PHQ-2 in patients with infertility. Methods In this cross-sectional study, a total of 539 patients with infertility from a referral infertility clinic in Tehran, Iran completed the PHQ-9, along with other relevant scales: the WHO-five Well-being Index (WHO-5), the Hospital Anxiety and Depression Scale (HADS), and the Generalized Anxiety Disorder-7 (GAD-7). Factor structure and internal consistency of PHQ-9 were examined via confirmatory factor analysis (CFA) and Cronbach’s alpha, respectively. Convergent validity was evaluated by relationship with WHO-5, HADS and GAD-7. Results The mean total PHQ-9 and PHQ-2 scores were 8.47 ± 6.17 and 2.42 ± 1.86, respectively, and using a cut-off value of 10 (for PHQ-9) and 3 (for PHQ-2), the prevalence of depressive symptoms was 38.6 and 43.6%, respectively. The Cronbach’s alphas for PHQ-9 and PHQ-2 were, respectively, 0.851 and 0.767, indicating good internal consistency. The CFA results confirmed the one-factor model of the PHQ-9 (χ2/df = 4.29; CFI = 0.98; RMSEA = 0.078 and SRMR = 0.044). Both PHQ-9 and PHQ-2 showed moderate to strong correlation with the measures of WHO-5, HADS-depression, HADS-anxiety, and the GAD-7, confirming convergent validity. In univariate analysis, female sex, long infertility duration, and unsuccessful treatment were significantly associated with depression symptoms. Conclusion Both PHQ-9 and PHQ-2 are brief and easy to use measures of depressive symptoms with good psychometric properties that appear suitable for routine use in patients with infertility.

scholarly journals The Blurred Line between Physical Ageing and Mental Health in Older Adults: Implications for the Measurement of Depression

2019 ◽  
Vol 10 ◽  
pp. 117955731988563
Author(s):  
Cassie M Hazell ◽  
Helen E Smith ◽  
Christina J Jones
Keyword(s):  
Older Adults ◽  
Discriminant Validity ◽  
Psychological Symptoms ◽  
Adult Population ◽  
The Elderly ◽  
Depression Symptoms ◽  
Physical Ageing ◽  
Conceptual Similarity ◽  
Symptoms Of Depression ◽  
General Adult Population

Objectives: Depression in older adults is assessed using measures validated in the general adult population. However, such measures may be inappropriate in the elderly due to the similarities between ageing and the symptoms of depression. This article discusses whether these measures are fit for the purpose and the implications of using inappropriate tools. Methods: A commentary on measuring depression in older adults. Results: Depression symptoms may be mistaken for signs of ageing. Several measures of depression include items that may have a physical cause and thus generate measurement error. Those studies that have assessed the psychometric properties of depression measures in older adults have failed to conduct appropriate assessments of discriminant validity. Discussion: Research is needed to determine whether the conceptual similarity between some symptoms of depression and the effects of ageing translate to factorial similarity. If so, there may be a need for a specific depression measure for older adults that prioritises psychological symptoms.

scholarly journals Age sequences of the elderly’ social network and its efficacies on well-being: an urban-rural comparison in China

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Zhenhua Zheng ◽  
Hong Chen
Keyword(s):  
Social Network ◽  
Rural Areas ◽  
Age Groups ◽  
Well Being ◽  
The Elderly ◽  
Urban Elderly ◽  
Family Network ◽  
The Social ◽  
Urban Rural ◽  
Urban And Rural Areas

Abstract Background Although social network is a known determinant of the elderly’s well-being, it is not clear, in urban-rural and age-comparison, what its structural characteristics are and how it works for well-being. The research aims to discuss the features of the elderly’s social network and the social network efficacies on the well-being of older adults in China’s urban and rural areas as well as revealing the urban-rural disparities among the elderly of different age groups. Methods In this study, descriptive statistical analysis and structural equation Modeling (SEM) were used to make a group comparison between the urban and rural elderly of different age groups. All data are quoted from 2014 China Longitudinal Aging Social Survey (CLASS). The survey adopted the multi-stage probability sampling method, targeting Chinese senior citizens aged 60 and above, the ultimate samples totaled 11,511. Results The social network of the elderly in China feature a “reverse structure” in age sequences: with ageing, family network of the elderly expand while their friend network shrink; also, the expansion scale of the rural elderly’s family network is significantly larger than that of the city’s while the shrinkage scale of their friend network is smaller compared with its urban counterpart. The effect of family network on the rural elderly’s well-being shows a remarkable increase with age. However, there is no noticeable change in urban elderly groups of different ages. Conclusion The social network characteristics of the Chinese elderly are different between different age stages. Namely, the family network and the friend network have the “reverse structure “ in age sequences. Meanwhile, the family network and the friend network have different efficacies on the well-being of the elderly in China, and the differences between urban and rural areas are even more obvious. For rural elderly, family network has very important effects on their well-being. Moreover, With the increase of age, family network’s efficacies increase gradually. For urban elderly, comparatively, family network is just as important as friend network.

Prevalence of mental disorders in non-demented elderly people in primary care

2015 ◽  
Vol 27 (5) ◽  
pp. 757-768 ◽  
Author(s):  
Luisa Baladón ◽  
Ana Fernández ◽  
Maria Rubio-Valera ◽  
Jorge Cuevas-Esteban ◽  
Diego J. Palao ◽  
...  
Keyword(s):  
Primary Care ◽  
Mental Disorders ◽  
Mental Disorder ◽  
Perceived Stress ◽  
Age Groups ◽  
Well Being ◽  
The Elderly ◽  
Cross Sectional Survey ◽  
Somatic Comorbidity ◽  
Axis I

ABSTRACTBackground:Mental disorders in the elderly are common, with a 12-month prevalence in the community ranging from 8.54% to 26.4%. Unfortunately, many mental disorders are unrecognized, untreated, and associated with poor health outcomes. The aim of this paper is to describe the prevalence of mental disorders in the elderly primary care (PC) population and its associated factors by age groups.Methods:Cross-sectional survey, conducted in 77 PC centers in Catalonia (Spain), 1,192 patients over 65 years old. The prevalence of mental disorders was assessed through face-to-face evaluations using the Structured Clinical Interview for DSM-IV Axis I Disorders, Research Version (SCID-I-RV) and the Mini International Neuropsychiatric Interview (MINI); chronic physical conditions were noted using a checklist; and disability through the Sheehan Disability Scales (SDS).Results:Nearly 20% of participants had a mental disorder in the previous 12 months. Anxiety disorders were the most frequent, (10.9%) (95% CI = 8.2–14.4), followed by mood disorders (7.4%) (95% CI = 5.7–9.5). Being female, greater perceived stress and having mental health/emotional problems as the main reason for consultation were associated with the presence of any mental disorder. There were no differences in prevalence across age groups. Somatic comorbidity was not associated with the presence of mental disorders.Conclusions:Mental disorders are highly prevalent among the elderly in PC in Spain. Efforts are needed to develop strategies to reduce this prevalence and improve the well-being of the elderly. Based on our results, we thought it might be useful to assess perceived stress regularly in PC, focusing on people who consult for emotional distress, or that have greater perceived stress.

scholarly journals Eye tracking and attentional bias for depressive internet memes in depression

2020 ◽  
Author(s):  
Umair Akram ◽  
Jason G. Ellis ◽  
Glhenda Cau ◽  
Frayer Hershaw ◽  
Ashlieen Rajenthran ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Eye Movements ◽  
Attentional Bias ◽  
Control Group ◽  
Depression Symptoms ◽  
Significant Group ◽  
Symptoms Of Depression ◽  
Total Fixation ◽  
Potential Benefits ◽  
Type Interaction

AbstractPrevious research highlights the potential benefits of engaging with depressive internet memes for those experiencing symptoms of depression. This study aimed to determine whether: compared to non-depressed controls, individuals experiencing depressive symptoms were quicker to orient and maintain overall attention for internet memes depicting depressive content relative to neutral memes. N = 21 individuals were grouped based on the severity of reported depression symptoms using the PhQ-9. Specifically, a score of:  ≤ 4 denoted the control group; and  ≥ 15 the depressive symptoms group. Participants viewed a series of meme pairs depicting depressive and neutral memes for periods of 4000 ms. Data for the first fixation onset and duration, total fixation count and total fixation and gaze duration of eye-movements were recorded. A significant group x meme-type interaction indicated that participants with depressive symptoms displayed significantly more fixations on depressive rather than neutral memes. These outcomes provide suggestive evidence for the notion that depressive symptoms are associated with an attentional bias towards socio-emotionally salient stimuli.

scholarly journals Effects of exercise training on quality of life, symptoms of depression, symptoms of anxiety and emotional well-being in type 2 diabetes mellitus: a systematic review

Diabetologia ◽  
2013 ◽  
Vol 56 (6) ◽  
pp. 1210-1225 ◽  
Author(s):  
M. M. P. van der Heijden ◽  
F. E. P. van Dooren ◽  
V. J. M. Pop ◽  
F. Pouwer
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Systematic Review ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Well Being ◽  
Depression Symptoms ◽  
Symptoms Of Depression
Sign in / Sign up

Export Citation Format

Share Document