Medical Relief Mission to Bosnia/Hercegovina: A Case Report

1997 ◽  
Vol 12 (2) ◽  
pp. 96-101 ◽  
Author(s):  
James R. Tryon
Keyword(s):  
Disaster Medicine ◽  
Regional Hospital ◽  
General Anesthetic ◽  
Industrial City ◽  
The Past ◽  
Anesthetic Agents ◽  
Medical Supplies ◽  
Private Organization ◽  
Medical Relief ◽  
The U.S

AbstractWorld attention has been focused on Bosnia/Hercegovina, where war erupted in 1992. The regional hospital of Mostar, an industrial city with a population of 100,000, operated -with chronic shortages of medical supplies including general anesthetic agents. In February 1992, just prior to the referendum for independence in that republic, a shipment of medical supplies with anesthesics, food, and clothing was delivered safely to Ljubuski, a village near Mostar, for Mostar hospital and surrounding clinics by a small, private organization from Birmingham, Alabama. No difficulties were encountered in delivering the supplies despite warnings from the U.S. State Department, the lengthy transit from Austria through Croatia to Bosnia, an active black market, and the inexperience of the relief agency. This disaster relief effort by a small, private sponsor was representative of both the positive aspects of such a project, as well as typical negative aspects. These efforts had been discouraged in the past, but as disaster medicine matures, there may be room for such endeavors, if properly directed.

Novel Drugs and Biologics of 2016: A Boom for Neurodrugs in the Pipelin

2017 ◽  
Vol 10 (5) ◽  
pp. 3809-3814
Author(s):  
D Samba Reddy
Keyword(s):  
Muscular Atrophy ◽  
Clinical Care ◽  
New Drugs ◽  
Essential Medicines ◽  
High Demand ◽  
The Past ◽  
Novel Drugs ◽  
Innovative Products ◽  
Cns Drugs ◽  
The U.S

This article provides a brief overview of novel drugs approved by the U.S. FDA in 2016.  It also focuses on the emerging boom in the development of neurodrugs for central nervous system (CNS) disorders. These new drugs are innovative products that often help advance clinical care worldwide, and in 2016, twenty-two such drugs were approved by the FDA. The list includes the first new drug for disorders such as spinal muscular atrophy, Duchenne muscular dystrophy or hallucinations and delusions of Parkinson’s disease, among several others. Notably, nine of twenty-two (40%) were novel CNS drugs, indicating the industry shifting to neurodrugs. Neurodrugs are the top selling pharmaceuticals worldwide, especially in America and Europe. Therapeutic neurodrugs have proven their significance many times in the past few decades, and the CNS drug portfolio represents some of the most valuable agents in the current pipeline. Many neuroproducts are vital or essential medicines in the current therapeutic armamentarium, including dozens of “blockbuster drugs” (drugs with $1 billion sales potential).  These drugs include antidepressants, antimigraine medications, and anti-epilepsy medications. The rise in neurodrugs’ sales is predominantly due to increased diagnoses of CNS conditions. The boom for neuromedicines is evident from the recent rise in investment, production, and introduction of new CNS drugs.  There are many promising neurodrugs still in the pipeline, which are developed based on the validated “mechanism-based” strategy. Overall, disease-modifying neurodrugs that can prevent or cure serious diseases, such as multiple sclerosis, epilepsy, and Alzheimer’s disease, are in high demand. 

Proton Hopping In Living Systems.

2020 ◽  
Vol 16 ◽  
Author(s):  
Lemont Kier
Keyword(s):  
Living Systems ◽  
Specific Information ◽  
General Anesthetic ◽  
Memory Functions ◽  
Anesthetic Agents ◽  
Drug Receptor

: This review focuses on the two-century old concept of proton hopping. Introduced in 1806 by Grottus, it has evolved into an explanation of great diversity in describing many functions in living systems. It is a process involving water, which expands on the belief that life exists only in the presence of water. This review describes the mechanism of the process as it carries information through water. A focus is initially made on the process in water in the nerve systems. The nature of the process in these systems is described as the passage of proton hopping in living systems. In drug-receptor encounters, proton hopping is initiated, carrying specific information from these specialized encounters. The review continues with an explanation of sleep, arising from an alteration in proton hopping. A similar phenomenon of the effect of general anesthetic agents is described, as they interfere with by proton hopping. Finally, memory functions are addressed in the realm of events carried by proton hopping.

The Future of FBI Counterintelligence through the Lens of the Past Hundred Years

2010 ◽  
pp. 504-517
Author(s):  
Raymond J. Batvinis
Keyword(s):  
United States ◽  
The United States ◽  
Main Concern ◽  
Federal Bureau ◽  
The Past ◽  
Intelligence Services ◽  
Terrorist Groups ◽  
Foreign Intelligence ◽  
Key Events ◽  
The U.S

Counterintelligence is the business of identifying and dealing with foreign intelligence threats to a nation, such as the United States. Its main concern is the intelligence services of foreign states and similar organizations of non-state actors, such as transnational terrorist groups. Counterintelligence functions both as a defensive measure that protects the nation's secrets and assets against foreign intelligence penetration and as an offensive measure to find out what foreign intelligence organizations are planning to defeat better their aim. This article addresses the Federal Bureau of Investigation's (FBI) foreign counterintelligence function. It briefly traces its evolution by examining the key events and the issues that effected its growth as the principle civilian counterintelligence service of the U.S. government.

scholarly journals General anesthesia with remimazolam in a patient with mitochondrial encephalomyopathy: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Yuji Suzuki ◽  
Matsuyuki Doi ◽  
Yoshiki Nakajima
Keyword(s):  
Lactic Acidosis ◽  
General Anesthesia ◽  
Mitochondrial Disease ◽  
Muscle Relaxation ◽  
Anesthetic Management ◽  
Perioperative Period ◽  
Mitochondrial Encephalomyopathy ◽  
Anesthesia Induction ◽  
General Anesthetic ◽  
Anesthetic Agents

Abstract Background Systemic anesthetic management of patients with mitochondrial disease requires careful preoperative preparation to administer adequate anesthesia and address potential disease-related complications. The appropriate general anesthetic agents to use in these patients remain controversial. Case presentation A 54-year-old woman (height, 145 cm; weight, 43 kg) diagnosed with mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes underwent elective cochlear implantation. Infusions of intravenous remimazolam and remifentanil guided by patient state index monitoring were used for anesthesia induction and maintenance. Neither lactic acidosis nor prolonged muscle relaxation occurred in the perioperative period. At the end of surgery, flumazenil was administered to antagonize sedation, which rapidly resulted in consciousness. Conclusions Remimazolam administration and reversal with flumazenil were successfully used for general anesthesia in a patient with mitochondrial disease.

scholarly journals Immunizing the Flock: How the Pandemic Court Rewrote Religious Freedom

Laws ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 12
Author(s):  
Paul Baumgardner
Keyword(s):  
United States ◽  
Supreme Court ◽  
Legal System ◽  
Religious Freedom ◽  
The United States ◽  
Religious Practices ◽  
The Past ◽  
The U.S

When coronavirus began to descend upon the United States, religious freedom advocates across the country sounded the alarm that citizens’ religious practices and institutions were under threat. Although some of the most extreme arguments championed by these advocates were not validated by our legal system, many were. This article explores the underappreciated gains made by religious freedom advocates before the U.S. Supreme Court over the past year. As a result of the “Pandemic Court”, religious freedom in the United States has been rewritten. This promises to radically change the educational, employment, and health prospects of millions of Americans for the rest of the pandemic and long afterwards.

The past is prologue

2018 ◽  
Vol 17 (3) ◽  
pp. 366-385 ◽  
Author(s):  
David Cassels Johnson ◽  
Crissa Stephens ◽  
Stephanie Gugliemo Lynch
Keyword(s):  
Language Policy ◽  
Language Ideologies ◽  
Public Policies ◽  
Social Structures ◽  
New Latino Diaspora ◽  
Policy Initiatives ◽  
The Past ◽  
Historical Processes ◽  
The U.S

Abstract This article examines reactions to the changing linguistic ecology in the U.S. state of Iowa, which is experiencing a demographic phenomenon often referred to as the New Latino Diaspora (NLD) (Hamann et al., 2002). We first examine the historical processes and social structures that link current language policy initiatives within Iowa to local and national nativism. We then analyze public policies and texts to reveal how language ideologies circulate across diverse texts and contexts, forming discourses that shape the experiences of Latin@s in Iowa.

The Madness beyond MAD—Current American Nuclear Strategy

1984 ◽  
Vol 17 (01) ◽  
pp. 33-40
Author(s):  
Robert Jervis
Keyword(s):  
Nuclear Weapons ◽  
Reagan Administration ◽  
Military Power ◽  
Nuclear Strategy ◽  
The Past ◽  
Means And Ends ◽  
Soviet Force ◽  
Nuclear Policy ◽  
The Impact ◽  
The U.S

A rational strategy for the employment of nuclear weapons is a contradiction in terms. The enormity of the destruction, either executed or threatened, severs the nexus of proportionality between means and ends which used to characterize the threat and use of force. This does not mean, however, that all nuclear strategies are equally irrational. The nuclear policy of the Reagan administration—which is essentially the same as that of the Carter administration and which has its roots in developments initiated by even earlier administrations—is particularly ill-formed. As I will demonstrate, the basic reason for this is that the strategy rests on a profound underestimation of the impact of nuclear weapons on military strategy and attempts to understand the current situation with intellectual tools appropriate only in the pre-nuclear era.American strategy for the past several years—the “countervailing strategy”—has been based on the assumption that what is crucial is the ability of American and allied military forces to deny the Soviets military advantage from any aggression they might contemplate. The U.S. must be prepared to meet and block any level of Soviet force. The strategy is then one of counterforce—blocking and seeking to destroy Soviet military power. The goal is deterrence. Although it is concerned with how the U.S. would fight many different kinds of wars, both nuclear and non-nuclear, it is not correct to claim that the strategy seeks to engage in wars rather than deter them.

scholarly journals How Effective Are Existing Phosphorus Management Strategies in Mitigating Surface Water Quality Problems in the U.S.?

2021 ◽  
Vol 13 (12) ◽  
pp. 6565
Author(s):  
Shama E. Haque
Keyword(s):  
Water Quality ◽  
Surface Water ◽  
Management Strategies ◽  
Surface Water Quality ◽  
Land Application ◽  
Water Soluble ◽  
Phosphorus Recovery ◽  
Water Bodies ◽  
The Past ◽  
The U.S

Phosphorus is an essential component of modern agriculture. Long-term land application of phosphorous-enriched fertilizers and animal manure leads to phosphorus accumulation in soil that may become susceptible to mobilization via erosion, surface runoff and subsurface leaching. Globally, highly water-soluble phosphorus fertilizers used in agriculture have contributed to eutrophication and hypoxia in surface waters. This paper provides an overview of the literature relevant to the advances in phosphorous management strategies and surface water quality problems in the U.S. Over the past several decades, significant advances have been made to control phosphorus discharge into surface water bodies of the U.S. However, the current use of phosphorus remains inefficient at various stages of its life cycle, and phosphorus continues to remain a widespread problem in many water bodies, including the Gulf of Mexico and Lake Erie. In particular, the Midwestern Corn Belt region of the U.S. is a hotspot of phosphorous fertilization that has resulted in a net positive soil phosphorous balance. The runoff of phosphorous has resulted in dense blooms of toxic, odor-causing phytoplankton that deteriorate water quality. In the past, considerable attention was focused on improving the water quality of freshwater bodies and estuaries by reducing inputs of phosphorus alone. However, new research suggests that strategies controlling the two main nutrients, phosphorus and nitrogen, are more effective in the management of eutrophication. There is no specific solution to solving phosphorus pollution of water resources; however, sustainable management of phosphorus requires an integrated approach combining at least a reduction in consumption levels, source management, more specific regime-based nutrient criteria, routine soil fertility evaluation and recommendations, transport management, as well as the development of extensive phosphorus recovery and recycling programs.

50th anniversary of the Department of Traumatology, Orthopedics and Disaster Medicine of A.I. Yevdokimov Moscow State University of Medicine and Dentistry

2021 ◽  
Vol 19 (3) ◽  
pp. 8-15
Author(s):  
N. V. YARYGIN ◽  
◽  
M. V. PARSHIKOV ◽  
I. G. CHEMYANOV ◽  
◽  
...  
Keyword(s):  
Detailed Analysis ◽  
50Th Anniversary ◽  
Disaster Medicine ◽  
Previous Experience ◽  
State University ◽  
Highly Qualified ◽  
Medical Work ◽  
The Past ◽  
Moscow State University

The purpose — to sum up the results of the work of the Department of Traumatology, Orthopedics and Disaster Medicine for 50 years. Material and methods. A detailed analysis was carried out of the stages of the Department development since its creation in 1971. The contribution of Professors Yu.V. Golyakhovskiy, A.S. Imamaliev, V.I. Zorya, N.V. Yarygin is highlighted. The achievements of the staff in scientific, educational, pedagogical and medical work over the past years are discussed.  Results. Today, the overall bed fund of the Traumatology and Orthopedics bases of the Department is 300 beds. Only in 2019-2020, according to the results of studies conducted in clinics, 155 scientific articles and theses were published, 92 reports were made, two patents for inventions were obtained. Two textbooks, two training manuals on traumatology and orthopedics, and two monographs were published. The 4th and the 5th International Pirogov Forums were organized, with the leading Russian and foreign specialists as speakers. Conclusion. The Professors of the Department of Traumatology, Orthopedics and Disaster Medicine are highly qualified specialists, renowned in the sphere of Traumatology, Orthopedics and Disaster Medicine. The collective of the Department of Traumatology, Orthopedics and Disaster Medicine, relying on the previous experience and traditions, is energetic and confident on its anniversary.

Surgical treatment for acute testicular diseases in boys

1985 ◽  
Vol 66 (5) ◽  
pp. 375-375
Author(s):  
A. I. Papikyan
Keyword(s):  
Surgical Treatment ◽  
Regional Hospital ◽  
The Past

In the children's regional hospital in Kirov, over the past 5 years, 88 children aged from 2 months to 14 years have been treated for acute testicular diseases.

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