scholarly journals The impact of socioeconomic and stimulus inequality on human brain physiology

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Dhanya Parameshwaran ◽  
S. Sathishkumar ◽  
Tara C. Thiagarajan
Keyword(s):  
Animal Studies ◽  
Human Society ◽  
Spectral Parameters ◽  
Brain Physiology ◽  
Brain Signals ◽  
Key Aspects ◽  
The Impact ◽  
The Brain ◽  
Motorized Transport ◽  
Stimulus Environment

AbstractThe brain undergoes profound structural and dynamical alteration in response to its stimulus environment. In animal studies, enriched stimulus environments result in numerous structural and dynamical changes along with cognitive enhancements. In human society factors such as education, travel, cell phones and motorized transport dramatically expand the rate and complexity of stimulus experience but diverge in access based on income. Correspondingly, poverty is associated with significant structural and dynamical differences in the brain, but it is unknown how this relates to disparity in stimulus access. Here we studied consumption of major stimulus factors along with measurement of brain signals using EEG in 402 people in India across an income range of $0.82 to $410/day. We show that the complexity of the EEG signal scaled logarithmically with overall stimulus consumption and income and linearly with education and travel. In contrast phone use jumped up at a threshold of $30/day corresponding to a similar jump in key spectral parameters that reflect the signal energy. Our results suggest that key aspects of brain physiology increase in lockstep with stimulus consumption and that we have not fully appreciated the profound way that stimulus expanding aspects of modern life are changing our brain physiology.

scholarly journals A Comprehensive Analysis of 2D&3D Video Watching of EEG Signals by Increasing PLSR and SVM Classification Results

2019 ◽  
Vol 63 (3) ◽  
pp. 425-434 ◽  
Author(s):  
Negin Manshouri ◽  
Temel Kayikcioglu
Keyword(s):  
3D Video ◽  
Support Vector ◽  
Least Squares Regression ◽  
Eeg Signals ◽  
3D Technology ◽  
Svm Classification ◽  
Brain Signals ◽  
Short Period ◽  
The Impact ◽  
The Brain

Abstract Despite the development of two- and three-dimensional (2D&3D) technology, it has attracted the attention of researchers in recent years. This research is done to reveal the detailed effects of 2D in comparison with 3D technology on the human brain waves. The impact of 2D&3D video watching using electroencephalography (EEG) brain signals is studied. A group of eight healthy volunteers with the average age of 31 ± 3.06 years old participated in this three-stage test. EEG signal recording consisted of three stages: After a bit of relaxation (a), a 2D video was displayed (b), the recording of the signal continued for a short period of time as rest (c), and finally the trial ended. Exactly the same steps were repeated for the 3D video. Power spectrum density (PSD) based on short time Fourier transform (STFT) was used to analyze the brain signals of 2D&3D video viewers. After testing all the EEG frequency bands, delta and theta were extracted as the features. Partial least squares regression (PLSR) and Support vector machine (SVM) classification algorithms were considered in order to classify EEG signals obtained as the result of 2D&3D video watching. Successful classification results were obtained by selecting the correct combinations of effective channels representing the brain regions.

scholarly journals Brain Physiology and Pathophysiology in Mental Stress

2013 ◽  
Vol 2013 ◽  
pp. 1-23 ◽  
Author(s):  
Karim Alkadhi
Keyword(s):  
Signal Transduction ◽  
Learning And Memory ◽  
Mental Stress ◽  
Negative Effects ◽  
Functional Changes ◽  
Brain Physiology ◽  
Brain Functions ◽  
Brain Structure And Function ◽  
The Impact ◽  
The Brain

Exposure to various forms of stress is a common daily occurrence in the lives of most individuals, with both positive and negative effects on brain function. The impact of stress is strongly influenced by the type and duration of the stressor. In its acute form, stress may be a necessary adaptive mechanism for survival and with only transient changes within the brain. However, severe and/or prolonged stress causes overactivation and dysregulation of the hypothalamic pituitary adrenal (HPA) axis thus inflicting detrimental changes in the brain structure and function. Therefore, chronic stress is often considered a negative modulator of the cognitive functions including the learning and memory processes. Exposure to long-lasting stress diminishes health and increases vulnerability to mental disorders. In addition, stress exacerbates functional changes associated with various brain disorders including Alzheimer’s disease and Parkinson’s disease. The primary purpose of this paper is to provide an overview for neuroscientists who are seeking a concise account of the effects of stress on learning and memory and associated signal transduction mechanisms. This review discusses chronic mental stress and its detrimental effects on various aspects of brain functions including learning and memory, synaptic plasticity, and cognition-related signaling enabled via key signal transduction molecules.

scholarly journals Understanding Drug Delivery to the Brain Using Liposome-Based Strategies: Studies that Provide Mechanistic Insights Are Essential

2021 ◽  
Vol 23 (6) ◽  
Author(s):  
Firda Juhairiyah ◽  
Elizabeth C. M. de Lange
Keyword(s):  
Drug Delivery ◽  
Drug Transport ◽  
Animal Studies ◽  
Time Course ◽  
Liposomal Formulation ◽  
Liposomal Drug ◽  
Brain Drug Delivery ◽  
Liposomal Formulations ◽  
The Impact ◽  
The Brain

AbstractBrain drug delivery may be restricted by the blood-brain barrier (BBB), and enhancement by liposome-based drug delivery strategies has been investigated. As access to the human brain is limited, many studies have been performed in experimental animals. Whereas providing interesting data, such studies have room for improvement to provide mechanistic insight into the rate and extent of specifically BBB transport and intrabrain distribution processes that all together govern CNS target delivery of the free drug. This review shortly summarizes BBB transport and current liposome-based strategies to overcome BBB transport restrictions, with the emphasis on how to determine the individual mechanisms that all together determine the time course of free drug brain concentrations, following their administration as such, and in liposomes. Animal studies using microdialysis providing time course information on unbound drug in plasma and brain are highlighted, as these provide the mechanistic information needed to understand BBB drug transport of the drug, and the impact of a liposomal formulations of that drug on BBB transport. Overall, these studies show that brain distribution of a drug administered as liposomal formulation depends on both drug properties and liposomal formulation characteristics. In general, evidence suggests that active transporters at the BBB, either being influx or efflux transporters, are circumvented by liposomes. It is concluded that liposomal formulations may provide interesting changes in BBB transport. More mechanistic studies are needed to understand relevant mechanisms in liposomal drug delivery to the brain, providing an improved basis for its prediction in human using animal data.

How reading in single- and multiple-column types influence our cognitive load: an EEG study

2019 ◽  
Vol 37 (4) ◽  
pp. 593-606 ◽  
Author(s):  
Hosam Al-Samarraie ◽  
Atef Eldenfria ◽  
Fahed Zaqout ◽  
Melissa Lee Price
Keyword(s):  
Cognitive Load ◽  
Cognitive Processing ◽  
Content Type ◽  
Brain Signals ◽  
Significant Difference ◽  
Reading Text ◽  
The Impact ◽  
Electroencephalogram Eeg ◽  
Instructional Design Practices ◽  
The Brain

Purpose The impact of different screen-based typography styles on individuals’ cognitive processing of information has not been given much consideration in the literature, though such differences would imply different learning outcomes. This study aims to enrich the current understanding of the impact of reading in single- and multiple-column types on students’ cognitive processing. Design/methodology/approach An electroencephalogram (EEG) was used to record and analyze the brain signals of 27 students while reading from single- and multiple- column layouts. Findings The results showed a significant difference in students’ cognitive load when reading text from different types of columns. All students exerted less processing efforts when text was presented in two-column format, thus experiencing less cognitive load. Originality/value Using EEG, this study examined the neural consequences of reading in single- and multiple-column types on cognitive load during reading. The findings can be used to enrich the current instructional design practices on how different typographical formats facilitate learners’ cognitive performance.

scholarly journals Key Aspects of Analytical and Transcendental Phenomenology within the Framework of Modern Philosophy of Consciousness

2019 ◽  
Vol 62 (5) ◽  
pp. 97-123
Author(s):  
Diana E. Gasparyan
Keyword(s):  
Transcendental Phenomenology ◽  
Phenomenal Consciousness ◽  
Phenomenological Approach ◽  
Natural World ◽  
Point Of View ◽  
Analytical Philosophy ◽  
Joint Research ◽  
Brain Physiology ◽  
Key Aspects ◽  
The Brain

The article discusses the peculiarities and specific features of phenomenological approach developed in contemporary analytical philosophy. Despite the fact that the trust in phenomenological approaches continue to grow in analytical philosophy, it is necessary to recognize the presence of noticeable divergence between the classical transcendental phenomenology of E. Husserl and contemporary versions of phenomenology in analytical philosophy. The article examines some of these divergences. It is shown that, unlike the skepticism of transcendental phenomenology in relation to scientific methodology in the research of consciousness, the analytical tradition of phenomenology is oriented toward cooperative dialogue with science. Phenomenology in analytical philosophy places great hopes on the possibility of making consciousness a subject of joint research of neuroscientists and phenomenologists. The article claims that in the course of realization of this task, phenomenology in analytical tradition often starts to be interpreted from realistic and partly from naturalistic positions, and that does not meet the project of transcendental phenomenology. As an illustration of this idea, certain approaches of analytical phenomenology are considered, in particular: phenomena are interpreted from the point of view of logical and linguistic analysis, intentionality is connected with the activity of the brain and is located in the natural world, phenomenal consciousness is interpreted as the awareness of a high order, and the phenomena have a gradual nature and are often identified only with sensual experience, which implies a correlative correspondence of the substrate data of brain physiology. In that regard, there are reasons to interpret phenomenological theories that are funded by analytical tradition as an example of a specific phenomenology of non-transcendental origin.

scholarly journals The Effect of Brain Teaser Games on the Attention of Players Based on Hormonal and Brain Signals Changes

2021 ◽  
Author(s):  
Hamed Aliyari ◽  
◽  
Hedayat Sahraei ◽  
Sahar Golabi ◽  
Masoomeh Kazemi ◽  
...  
Keyword(s):  
Computer Games ◽  
Alpha Amylase ◽  
Control Group ◽  
Recording Device ◽  
Brain Signals ◽  
Before And After ◽  
Cortisol Levels ◽  
The Impact ◽  
The Brain ◽  
Experimental Group

Introduction: Today, evaluation and determination of the impact of computer games as an interactive media, play a significant role in cognitive and behavioral health of the individuals in the society. Computer games have been shown to have either positive or negative effects on cognitive indices among players. They also directly influence the lifestyle and quality of life of children, adolescents, and young adults. The present study was aimed to evaluate the short-term effects of the Brain Teaser game on players. Methods: Among forty-five male volunteers, a total of forty subjects with an average age of twenty years were recruited, and divided into two groups, the experimental group and control group. All required tests were conducted before and after the experimentation (playing the game) on the experimental group. Also, the tests were performed on control group, in which participants were not allowed to play the game. All assigned subjects completed a questionnaire, comprised of demographic characteristics and specific information regarding the game (e.g. game style and hours spent on playing the game). The saliva samples were collected to measure levels of Cortisol and Alpha Amylase. The salivary Alpha Amylase (sAA) and Cortisol levels were analyzed using a specific ELISA kit. Also, cognitive tests were performed using PASAT software before and after the game to assess perceptual-cognitive abilities of the players. The Brain waveforms were acquired by a 14-channel Emotiv brain signal recording device before and after the experimentation. Data analysis was conducted using R and MATLAB software. Results: PASAT test suggested that mental health and sustained attention were significantly improved, after the experimentation. In addition, the sAA and salivary Cortisol levels were significantly higher prior to the experimentation. The results of the brainwave analysis revealed that stress index and attention were significantly higher before the experimentation. Conclusion: Findings of the present study suggest that Brain Teaser games positively influence the central nervous system, and activate stress path, leading to changes in brain signals and subsequently improved cognitive elements, such as attention among players.

Effect of Trabecular Architecture on Transferring Load/Impact to the Brain: A Local Model of Single Trabecula

2011 ◽  
Author(s):  
Parisa Saboori ◽  
Ali Sadegh
Keyword(s):  
Subarachnoid Space ◽  
External Load ◽  
Animal Studies ◽  
Trabecular Architecture ◽  
Local Models ◽  
Pia Mater ◽  
The Impact ◽  
External Loads ◽  
The Brain ◽  
Load Impact

In this paper the mechanotransduction of the external load through the trabeculae in the subarachnoid space (SAS) was investigated. This has been accomplished by employing the results of our animal studies, i.e. the histology and architecture of trabeculae, and by creating local models consist of a trabecula. It is concluded that the trabeculae are mainly configured as an upright tree-like shaped, where the branches are attached to the pia mater and the stems are attached to the arachnoid. The result of the analysis reveal that said configuration of the trabeculae creates less strain in the brain when the head in subjected to external loads, and thereby damps the impact.

NON-INVASIVE BCI METHOD: EEG - ELECTROENCEPHALOGRAPHY

2019 ◽  
pp. 139-145
Author(s):  
Selma Büyükgöze
Keyword(s):  
Brain Computer Interface ◽  
Computer Interface ◽  
Electrode Placement ◽  
Eeg Signals ◽  
Non Invasive ◽  
Brain Signals ◽  
Brain States ◽  
The Brain

Brain Computer Interface consists of hardware and software that convert brain signals into action. It changes the nerves, muscles, and movements they produce with electro-physiological signs. The BCI cannot read the brain and decipher the thought in general. The BCI can only identify and classify specific patterns of activity in ongoing brain signals associated with specific tasks or events. EEG is the most commonly used non-invasive BCI method as it can be obtained easily compared to other methods. In this study; It will be given how EEG signals are obtained from the scalp, with which waves these frequencies are named and in which brain states these waves occur. 10-20 electrode placement plan for EEG to be placed on the scalp will be shown.

Particularities of the independent auditor's report on reliability of accounting (financial) statements for 2019: COVID-19 as qualitatively essential information (Part 2)

2020 ◽  
Vol 23 (7) ◽  
pp. 777-799
Author(s):  
O.I. Shvyreva ◽  
Z.I. Kruglyak ◽  
A.V. Petukh
Keyword(s):  
Financial Reporting ◽  
Financial Statements ◽  
Economic Situation ◽  
Risk Disclosure ◽  
Essential Information ◽  
Logical Method ◽  
Annual Reporting ◽  
The Face ◽  
Key Aspects ◽  
The Impact

Subject. This article discusses the issues related to the practice of financial reporting in the face of uncertainties caused by the coronavirus contagion, as well as the specifics of the audit strategy and formation of an audit opinion on this reporting. Objectives. The article aims to identify the quality characteristics of financial reporting prepared in the context of the COVID-19 pandemic and justify the key aspects of assurance engagement completion in an extremely uncertain epidemiological and economic situation. Methods. For the study, we used an abstract-logical method, content analysis techniques, systematization, and classification. Results. Analyzing the impact of the extremely uncertain epidemiological and economic situation on financial statements, the article clarifies aspects of disclosure of events after the reporting date and threats to business continuity in the annual reporting of economic entities. The article identifies possible alternative procedures and algorithms to obtain proper evidence when it is insufficient in the face of the inability to meet certain audit standards requirements in a remote audit environment. The article defines the impact of COVID-19 risk disclosure on the structure of the audit report and opinion. Relevance. The results of the study can be used in the practical activities of economic entities that prepare financial statements in the face of significant uncertainty, as well as auditors and audit organizations.

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