A rhodamine B-based lysosomal pH probe

2015 ◽  
Vol 3 (5) ◽  
pp. 919-925 ◽  
Author(s):  
Shi-Li Shen ◽  
Xin-Peng Chen ◽  
Xiao-Fan Zhang ◽  
Jun-Ying Miao ◽  
Bao-Xiang Zhao

A novel rhodamine B-based lysosomal pH probe RML was developed. RML responded to acidic pH with short response time, high selectivity and high sensitivity and could detect lysosomal pH change in living cells.

2013 ◽  
Vol 96 (1) ◽  
pp. 71-75 ◽  
Author(s):  
Zhi-Qiang Hu ◽  
Ming Li ◽  
Ming-Dong Liu ◽  
Wen-Ming Zhuang ◽  
Guang-Ke Li

2013 ◽  
Vol 295-298 ◽  
pp. 475-478 ◽  
Author(s):  
Zhi Xiang Han ◽  
Ming Hui Du ◽  
Guo Xi Liang ◽  
Xiang Yang Wu

Rhodamine B thiohydrazide (RBS) was firstly employed as turn-on fluorescent probe for hypochlorite in aqueous solution and living cells. It exhibits a stable response to hypochlorite from 1.0×10-6to 1.0×10-5M with a detection limit of 3.3×10-7M. The response of this probe to hypochlorite is fast and highly selective compared with other reactive oxygen species (such as.OH,1O2, H2O2) and other common anions (such as X-, ClO2-, ClO4-, NO3-, NO2-, OH-, Ac-, CO32-, SO42-).


RSC Advances ◽  
2016 ◽  
Vol 6 (90) ◽  
pp. 87110-87114 ◽  
Author(s):  
Dongjian Zhu ◽  
Yanghe Luo ◽  
Xiaowei Yan ◽  
Wei Xie ◽  
Wen Cai ◽  
...  

FP can detect Cu2+ in complete aqueous solution with a rapid response time, high sensitivity, and high selectivity.


2018 ◽  
Vol 35 (3) ◽  
pp. 153-157 ◽  
Author(s):  
Samuel Zuk ◽  
Alena Pietrikova ◽  
Igor Vehec

Purpose The purpose of this paper is to analyse the possibilities of mechanical switch replacement by capacitive film touch sensor in applications requiring high reliability and short response time. Advantage of replacing mechanical switch by capacitive touch sensor is no mechanical wear and possible implementation of sensor in application where the switch could not be used or where the flexibility of the sensor substrate is required. The aim of this work is to develop a capacitive touch sensor with the advantage of maximum mechanical resistance, short response time and high sensitivity. Design/methodology/approach Based on various possible sensors layouts, the authors realized 18 different (14 self-capacitance and four mutual capacitance) topologies of capacitive sensor for touch applications. Three different technologies – PCB, LTCC and polymer technology – were used to characterize sensor’s behaviour. For precise characterization of different layouts realized on various substrates, the authors used integrated circuit FDC2214 capacitance-to-digital converter. Findings Sensing range of the capacitive touch (proximity) sensor is affected by the per cent of area covered by the sensor, and it does not depend on topology of sensor. The highest sensing range offers PCB technology. Flexible substrates can be used as proper substituent to rigid PCB. Originality/value The novelty of this work lies in finding the touch capacitive sensors that allow shorter switching times compared to standard mechanical switches.


RSC Advances ◽  
2016 ◽  
Vol 6 (43) ◽  
pp. 37085-37092 ◽  
Author(s):  
Ying Yang ◽  
Li Sun ◽  
Xiangting Dong ◽  
Hui Yu ◽  
Tingting Wang ◽  
...  

Fe3O4nanoparticles-decorated reduced graphene oxide nanocomposites have been successfully synthesized using solvothermal-pyrolytic method. They have superior gas sensing performance with low detection limit, high sensitivity and short response time.


The Analyst ◽  
2019 ◽  
Vol 144 (1) ◽  
pp. 331-341 ◽  
Author(s):  
Bhupendra Kumar Dwivedi ◽  
Roop Shikha Singh ◽  
Afsar Ali ◽  
Vinay Sharma ◽  
Shaikh M. Mobin ◽  
...  

Piperazine appended naphthalimide-BODIPYs (NPB1–NPB4) exhibiting solvatochromism, aggregation-induced emission, and high selectivity towards lysosomal pH in living cells have been described.


Biosensors ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 130
Author(s):  
Ruo-Jun Man ◽  
Meng-Ke Wu ◽  
Bing Yang ◽  
Yu-Shun Yang

In this work, a novel fluorescent probe with first-time-selected thiazepine backbone, TZPzine-1, was developed for selective detection of hydrazine in water samples and living cells. Chosen from our recent anti-cancer agents, TZPzine-1 inferred structurally based advantages of the optical adjustability and the hydrazine-trapping approach. It also showed applicable properties including high sensitivity (LOD = 50 nM), wide linear range (0–15 equiv.), high selectivity (especially from competing species), rapid response (within 20 min), and practical steadiness in various pH (6.0–11.0) and temperature (15–50 °C) conditions. To satisfy the interdisciplinary requirements in environmental toxicology, TZPzine-1 was successfully applied in water samples and living cells. We hope that the information in this work, as well as the concept of monitoring the nitrogen cycle, may be referable for future research on systematic management.


2021 ◽  
Vol 17 (7) ◽  
pp. 1249-1272
Author(s):  
Xiao-Lin Wang ◽  
Xiao Han ◽  
Xiao-Ying Tang ◽  
Xiao-Jun Chen ◽  
Han-Jun Li

With the development of nanomaterials, fluorescent nanoprobes have attracted enormous attention in the fields of chemical sensing, optical materials, and biological detection. In this paper, the advantages of “off–on” fluorescent nanoprobes in disease detection, such as high sensitivity and short response time, are attentively highlighted. The characteristics, sensing mechanisms, and classifications of disease-related target substances, along with applications of these nanoprobes in cancer diagnosis and therapy are summarized systematically. In addition, the prospects of “off–on” fluorescent nanoprobe in disease detection are predicted. In this review, we presented information from all the papers published in the last 5 years discussing “off–on” fluorescent nanoprobes. This review was written in the hopes of being useful to researchers who are interested in further developing fluorescent nanoprobes. The characteristics of these nanoprobes are explained systematically, and data references and supports for biological analysis, clinical drug improvement, and disease detection have been provided appropriately.


RSC Advances ◽  
2019 ◽  
Vol 9 (22) ◽  
pp. 12585-12589 ◽  
Author(s):  
Fa-Heng Zhang ◽  
Rui-Xue Jiang ◽  
Wei Cao ◽  
Bin Du ◽  
Ding-Yuan Cao ◽  
...  

Anisotropic fluorescent nanofibers constructed from the self-assembled perylene bisimide derivative and poly(vinylidene fluoride) show high sensitivity and short response time to aniline vapor.


2014 ◽  
Vol 196 ◽  
pp. 194-202 ◽  
Author(s):  
Jianlin Hu ◽  
Fan Wu ◽  
Shuo Feng ◽  
Jiahui Xu ◽  
Zhenghao Xu ◽  
...  
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