Iron-induced peroxidation of trilinolein nano-emulsions under model gastric conditions and its inhibition by dietary phenolic antioxidants

Background: Pomegranate peels are rich in bioactive compounds and could be an alternative natural source such as antioxidants. Aims: The aim of the present study was to assess the abilities of five solvents to extract phenolic antioxidants from pomegranate peels. Methods and Material: Pomegranate peels powder was subjected to extraction and the extraction yield was compared. The total phenolic, flavonoid, condensed and hydrolysable tannins contents were analyzed. The antioxidant activity of the extracts was evaluated by two methods (DPPH* and ABTS•+ scavenging capacities) and results were then compared. Results: Results showed that the mixture methanol/water (50:50) allowed higher extraction yield (37.33±5.3%) than the others solvents (P<0.05). Further, the total phenolic, flavonoid and condensed tannins contents were the highest in mixture water/methanol (50:50) extract. Phenolic antioxidants showed a distinct reducing capacity and a high DPPH* inhibition values were recorded for all extracts with no significant differences (P>0.05) between ethanol and mixture water/methanol (50:50) extracts. All extracts exhibited high inhibition against ABTS•+ but with a considerable variation. Phenolic content and antioxidant activities were well positively correlated with each other. Conclusions: Our findings revealed that the choice of the extracting solvent affects considerably the extraction of phenolic antioxidants from pomegranate peels. Keywords: Pomegranate peels, solvent extraction, antioxidant activity, phenolic antioxidants.

Lutein: Separation, Antioxidant Activity, and Potential Health Benefits

Antioxidant Measurement and Applications - ACS Symposium Series ◽

10.1021/bk-2007-0956.ch023 ◽

2007 ◽

pp. 352-372 ◽

Cited By ~ 3

Author(s):

Rong Tsao ◽

Mingchen Wang ◽

Zeyuan Deng

Keyword(s):

Antioxidant Activity ◽

Health Benefits ◽

Potential Health

Antioxidant Activity of Biphenolic Compounds Anchored on Mesoporous Alumina

Proceedings ◽

10.3390/ecsoc-23-06498 ◽

2019 ◽

Vol 41 (1) ◽

pp. 37

Author(s):

Vanina A. Guntero ◽

Cristián A. Ferretti ◽

Carla Ormachea ◽

Pedro M. E. Mancini ◽

María N. Kneeteman

Keyword(s):

Antioxidant Activity ◽

Antioxidant Properties ◽

Mesoporous Alumina ◽

Phenolic Antioxidants ◽

Radical Coupling ◽

Microwave Assisted ◽

Better Than

Phenolic antioxidants are used in the industry to delay the oxidation of fats, with the most used being butyl hydroxy anisole (BHA) and butyl hydroxy toluene (BHT). However, the consumer concern regarding their safety has motived the study of natural alternatives. In this sense, the aim of this work was to evaluate the behavior of 3,3′-dimethoxy-5,5′-di-2-propenyl-1,1′-biphenyl-2,2′-diol and 6,6′-dihidroxi-5,5′-dimethoxy-(1,1′-biphenyl)-3,3′-dicarbaldehyde free and supported on mesoporous alumina. Biphenolic compounds were synthetized by radical coupling and then anchored on alumina by microwave assisted process. The antioxidant activity of these compounds was investigated by phosphomolybdenum method. The results showed that biphenolic compounds anchored on mesoporous alumina have a marked antioxidant activity, better than free antioxidants. Biphenolic compounds supported on alumina display antioxidant properties allowing a new opportunity for the developing in food and cosmetics packaging.

The Nutritional Value of Non-Traditional Gluten-Free Flakes and Their Antioxidant Activity

Antioxidants ◽

10.3390/antiox8110565 ◽

2019 ◽

Vol 8 (11) ◽

pp. 565

Author(s):

Kristýna Šťastná ◽

Martina Mrázková ◽

Daniela Sumczynski ◽

Betül Cındık ◽

Erkan Yalçın

Keyword(s):

Antioxidant Activity ◽

High Performance ◽

Sugar Content ◽

Chenopodium Quinoa ◽

Biologically Active ◽

Eragrostis Tef ◽

Total Phenolic ◽

Phenolic Antioxidants ◽

In Vitro Digestibility

Nowadays, there is a growing interest for foods with a lower sugar content and rich in fiber and biologically active substances. The main purpose of this study was to prepare flakes from non-traditional pigmented cereals (Oryza sativa, Chenopodium quinoa, and Eragrostis tef) and to analyze their fibre, sugar, and in vitro digestibility values. Regarding phenolic antioxidants (soluble, soluble conjugated, and insoluble bound fractions), their content and antioxidant activity were measured using spectrophotometry and high performance liquid chromatography (HPLC) methods. Hydrothermally treated grains resulted in flakes with higher total dietary fibre contents (11.1–24.4%), quinoa and teff flakes were rich in maltose (up to 42.0 mg/g). Non-traditional flakes had lower in vitro digestibility, but conversely, they exhibited the highest phenolic contents corresponding with the highest antioxidant activity values (up to 2.33 mg Gallic acid equivalent/g of total phenolic content and 1.59 mg Trolox equivalent/g for 2,2-diphenyl-1-picrylhydrazyl (DPPH) in case of brown teff). Among free phenolics, the main contributors to an antioxidant activity were p-coumaric, o-coumaric, and gallic acids (r > 0.8186); among the soluble conjugated fractions, they were epigallocatechin, epicatechin, caffeic, and vanillic acids (r > 0.5935); while caffeic, protocatechuic, and ferulic acids (r > 0.5751) were the main contributors among the insoluble bound phenolics.

Functionality changes of natural antioxidants during food processing and storage

Czech Journal of Food Sciences ◽

10.17221/10617-cjfs ◽

2004 ◽

Vol 22 (SI - Chem. Reactions in Foods V) ◽

pp. S80-S83 ◽

Cited By ~ 1

Author(s):

J. Pokorný ◽

Š. Schmidt ◽

H. T T Nguyen

Keyword(s):

Antioxidant Activity ◽

Free Radicals ◽

Food Processing ◽

Degradation Products ◽

Raw Materials ◽

Natural Antioxidants ◽

Phenolic Antioxidants ◽

Oxidation Reactions ◽

Processing And Storage ◽

And Storage

Food raw materials and products contain inhibitors of oxidation reactions, both in the lipidic phase and the aqueous phase. The most important inhibitors are phenolic antioxidants. During food processing and storage, concentrations of antioxidants in the two phases reach an equilibrium. Phenolics react with lipidic free radicals, being converted into antioxidant free radicals, quinones, polymers and copolymers. Some degradation products possess an antioxidant activity, too. The relative antioxidant activity decreases with decreasing concentration of oxygen in the system and with increasing temperature. Antioxidants are more rapidly decomposed in surface layers. Health aspects of antioxidant degradation products are often neglected as the safety of antioxidant degradation products is mostly unknown.

Deposition Efficacy of Natural and Synthetic Antioxidants on Fabrics

Applied Sciences ◽

10.3390/app10186213 ◽

2020 ◽

Vol 10 (18) ◽

pp. 6213

Author(s):

Paola Giannì ◽

Heiko Lange ◽

Giulia Bianchetti ◽

Conny Joos ◽

David W. Brogden ◽

...

Keyword(s):

Antioxidant Activity ◽

Cotton Fabric ◽

Analytical Method ◽

Pine Bark ◽

Phenolic Antioxidants ◽

Synthetic Antioxidants ◽

Solid Matrices ◽

Natural And Synthetic

Pine bark extracts were tested as valid natural alternatives to common phenolic antioxidants to be deposited onto solid matrices. An analytical method for determining both deposition-efficacy and maintenance of antioxidant activity on fabrics surfaces was developed and successfully applied to phenolic antioxidants and pine tannins onto cotton fabric samples. Accumulated data suggest that common phenolic antioxidants and tannin contribute to an elevated antioxidant activity on fabric. A known source of odour is autoxidation of residual sebum on fabric, leading to the generation of malodourous compounds. Therefore, antioxidants hold the promise for mitigating malodour on fabrics, a top unmet consumer need around the globe.

Evaluation of a new benzothiazole derivative with antioxidant activity in the initial phase of acetaminophen toxicity

Arabian Journal of Chemistry ◽

10.1016/j.arabjc.2016.02.004 ◽

2019 ◽

Vol 12 (8) ◽

pp. 3871-3882 ◽

Cited By ~ 4

Author(s):

Laura C. Cabrera-Pérez ◽

Itzia I. Padilla-Martínez ◽

Alejandro Cruz ◽

Jessica E. Mendieta-Wejebe ◽

Feliciano Tamay-Cach ◽

...

Keyword(s):

Antioxidant Activity ◽

Initial Phase ◽

Acetaminophen Toxicity ◽

Benzothiazole Derivative

Phenolic Antioxidants and Antioxidant Activity in Pearling Fractions of Oat Groats

Journal of Cereal Science ◽

10.1006/jcrs.2000.0347 ◽

2001 ◽

Vol 33 (1) ◽

pp. 97-103 ◽

Cited By ~ 94

Author(s):

David M. Peterson ◽

Cheryld L. Emmons ◽

Alice H. Hibbs

Keyword(s):

Antioxidant Activity ◽

Phenolic Antioxidants

Determination of antioxidant activity of phenolic antioxidants in a Fenton-type reaction system by chemiluminescence assay

Analytical and Bioanalytical Chemistry ◽

10.1007/s00216-002-1692-1 ◽

2003 ◽

Vol 375 (3) ◽

pp. 376-380 ◽

Cited By ~ 36

Author(s):

Zhiyong Cheng ◽

Guangtao Yan ◽

Yuanzong Li ◽

Wenbao Chang

Keyword(s):

Antioxidant Activity ◽

Reaction System ◽

Phenolic Antioxidants ◽

Type Reaction ◽

Chemiluminescence Assay

Improvement of Phenolic Antioxidant-linked Cancer Cell Cytotoxicity of Grape Cell Culture Elicited by Chitosan and Chemical Treatments

HortScience ◽

10.21273/hortsci12248-17 ◽

2017 ◽

Vol 52 (11) ◽

pp. 1577-1584

Author(s):

Napaporn Sae-Lee ◽

Orapin Kerdchoechuen ◽

Natta Laohakunjit ◽

Benjawan Thumthanaruk ◽

Dipayan Sarkar ◽

...

Keyword(s):

Antioxidant Activity ◽

Cell Lines ◽

Cancer Cell ◽

Phenolic Content ◽

Cancer Cell Lines ◽

Phenolic Antioxidant ◽

Phenolic Antioxidants ◽

Vitro Assay ◽

Anticancer Properties ◽

Elicitor Treatments

Grape (Vitis vinifera cv. Pok Dum) is a rich source of health relevant phenolic antioxidants and can be targeted to mitigate chronic oxidative stress commonly associated with noncommunicable chronic diseases (NCDs), such as cancer. Furthermore, improving health relevant phenolic bioactives and associated antioxidant properties of fruits by using chemical elicitation strategy has significant merit. Based on this biochemical rationale, chitosan and other chemical elicitors potassium dihydrogen phosphate (KH2PO4), potassium nitrate (KNO3), sodium selenite (Na2SeO3), and aluminum sulphate [Al2(SO4)3] were targeted to improve phenolic bioactive profiles and associated antioxidant and anticancer properties of cultured grape cells grown for 28 days. After chemical elicitor treatments, phenolic content, resveratrol content, antioxidant activity, phenylalanine ammonia-lyase (PAL) enzyme activity, and cytotoxicity (cell inhibition) against cancer cell lines of cultured grape cells were investigated using in vitro assay models. Overall, stimulation of phenolic bioactives and improvement in associated cytotoxicity against cancer cell lines were found in cultured grape cells after chemical elicitation treatments. Chitosan and other chemical elicitors resulted in lower growth of cultured grape cells; however, they enhanced phenolic biosynthesis on a cell weight basis when compared with the control. Chemical elicitor treatments, such as Na2SeO3 (50 mg·L−1 and 100 mg·L−1) and Al2(SO4)3 (50 mg·L−1), resulted in enhanced phenolic content at the end of 14 days of culture (1.7, 1.4, and 1.0-fold increase, respectively). Higher accumulation of resveratrol and higher antioxidant activity with Al2(SO4)3 (50 mg·L−1) and Na2SeO3 (100 mg·L−1) elicitation treatments were also observed. Enhanced phenolic bioactives in cultured grape cells in response to chemical elicitation treatment, such as Na2SeO3, also resulted in higher cytotoxicity against different cancer cell lines. Therefore, this study indicates that chemical elicitors, such as Na2SeO3 and Al2(SO4)3, as well as chitosan in select doses can be targeted to improve phenolic bioactives and associated antioxidant and anticancer properties in cultured grape cells and such strategy has relevance for wider applications with other phenolic antioxidant-enriched fruits.