A hybrid hydrogel with in situ formed Ag-nanoparticles within 3D networks that exhibits broad antibacterial activities

A new hybrid hydrogel was constructed by in situ forming Ag NPs within the 3D network of a hydrogel that exhibits both excellent injectability and broad antibacterial activities, which makes it a potential candidate for various biomedical applications.

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A One-Pot Synthesis and Characterization of Antibacterial Silver Nanoparticle–Cellulose Film

Polymers ◽

10.3390/polym12020440 ◽

2020 ◽

Vol 12 (2) ◽

pp. 440 ◽

Cited By ~ 1

Author(s):

Qi-Yuan Chen ◽

Sheng-Ling Xiao ◽

Sheldon Q. Shi ◽

Li-Ping Cai

Keyword(s):

Composite Film ◽

Food Packaging ◽

Antibacterial Activities ◽

Light Transmittance ◽

Ag Nps ◽

One Pot ◽

One Pot Synthesis ◽

The One

Using N,N-dimethylacetamide (DMAc) as a reducing agent in the presence of PVP-K30, the stable silver nanoparticles (Ag-NPs) solution was prepared by a convenient method for the in situ reduction of silver nitrate. The cellulose–Ag-NPs composite film (CANF) was cast in the same container using lithium chloride (LiCl) giving the Ag-NPs-PVP/DMAc solution cellulose solubility as well as γ-mercaptopropyltrimethoxysilane (MPTS) to couple Ag-NPs and cellulose. The results showed that the Ag-NPs were uniformly dispersed in solution, and the solution had strong antibacterial activities. It was found that the one-pot synthesis allowed the growth of and cross-linking with cellulose processes of Ag-NPs conducted simultaneously. Approximately 61% of Ag-NPs was successfully loaded in CANF, and Ag-NPs were uniformly dispersed in the surface and internal of the composite film. The composite film exhibited good tensile properties (tensile strength could reach up to 86.4 MPa), transparency (light transmittance exceeds 70%), thermal stability, and remarkable antibacterial activities. The sterilization effect of CANF0.04 against Staphylococcus aureus and Escherichia coli exceed 99.9%. Due to low residual LiCl/DMAc and low diffusion of Ag-NPs, the composite film may have potential for applications in food packaging and bacterial barrier.

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Preparation of Hybrid Hydrogel Containing Ag Nanoparticles by a Green in Situ Reduction Method

Langmuir ◽

10.1021/la302011x ◽

2012 ◽

Vol 28 (30) ◽

pp. 11188-11194 ◽

Cited By ~ 41

Author(s):

Bihua Xia ◽

Qianling Cui ◽

Fang He ◽

Lidong Li

Keyword(s):

Ag Nanoparticles ◽

Reduction Method ◽

In Situ Reduction ◽

Hybrid Hydrogel

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Silver Nanoparticle-Based Nanocomposites for Combating Infectious Pathogens: Recent Advances and Future Prospects

Nanomaterials ◽

10.3390/nano11030581 ◽

2021 ◽

Vol 11 (3) ◽

pp. 581

Author(s):

Md A. Wahab ◽

Luming Li ◽

Hongmei Li ◽

Ahmed Abdala

Keyword(s):

Biomedical Applications ◽

Antibacterial Agents ◽

Structural Parameters ◽

Antibacterial Activities ◽

Food Preservation ◽

Resistant Bacteria ◽

Ag Nps ◽

Antibiotic Resistant ◽

The Impact ◽

Careful Investigation

Silver nanoparticles (Ag NPs) and their nanocomposites with polymers are potent agents for antibacterial and disinfectant applications. The structural parameters of Ag-NPs, such as size, shape, and surface area, are very critical for developing appropriate formulations for the targeted applications. The impact of these factors on the performance of Ag NPs is analyzed. Ag NPs with a broad spectrum of antibacterial activities have already found applications in wound and burn dressing, food preservation, agricultural ponds, treatment for infected areas, coatings, water treatment, and other biomedical applications. Ag NPs are quite useful against antibiotic-resistant bacteria, but their level of toxicity needs careful investigation as their toxicity could be very harmful to human health and the environment. This review discusses the challenges and prospects of various Ag NPs and their composites. The review will enrich the knowledge about the efficiency and mechanism of various Ag nanoparticle-based antibacterial agents.

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Hydroxyl-rich nanoporous carbon nanosheets synthesized by a one-pot method and their application in the in situ preparation of well-dispersed Ag nanoparticles

RSC Advances ◽

10.1039/c5ra18300f ◽

2015 ◽

Vol 5 (116) ◽

pp. 96062-96066 ◽

Cited By ~ 5

Author(s):

Xiaodi Guo ◽

Gaili Liu ◽

Shuang Yue ◽

Jing He ◽

Lianying Wang

Keyword(s):

Ag Nanoparticles ◽

High Surface ◽

High Surface Area ◽

Nanoporous Carbon ◽

Hydroxyl Groups ◽

Ag Nps ◽

One Pot ◽

Carbon Nanosheets ◽

In Situ Preparation

Nanoporous carbon nanosheets (CNSs) with high surface area have been synthesized by pyrolysis of organic–inorganic precursor. The CNSs with rich hydroxyl groups display remarkable reactivity and capability for in situ loading ultrafine Ag NPs.

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Enhancement of Energy Storage and Photoresponse Properties of Folic Acid–Polyaniline Hybrid Hydrogel by in Situ Growth of Ag Nanoparticles

ACS Applied Materials & Interfaces ◽

10.1021/acsami.6b09468 ◽

2016 ◽

Vol 8 (41) ◽

pp. 28055-28067 ◽

Cited By ~ 38

Author(s):

Sujoy Das ◽

Priyadarshi Chakraborty ◽

Sanjoy Mondal ◽

Arnab Shit ◽

Arun K. Nandi

Keyword(s):

Folic Acid ◽

Energy Storage ◽

Ag Nanoparticles ◽

In Situ Growth ◽

Hybrid Hydrogel

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Highly sensitive and colorimetric detection of hydrogen sulphide by in situ formation of Ag2S@Ag nanoparticles in polyelectrolyte multilayer film

RSC Advances ◽

10.1039/c4ra11526k ◽

2015 ◽

Vol 5 (5) ◽

pp. 3508-3511 ◽

Cited By ~ 5

Author(s):

Hongxia Fu ◽

Xinrui Duan

Keyword(s):

Hydrogen Sulphide ◽

Ag Nanoparticles ◽

Multilayer Film ◽

Colorimetric Detection ◽

Ag Nps ◽

Polyelectrolyte Multilayer ◽

Highly Sensitive ◽

In Situ Formation ◽

Polyelectrolyte Multilayer Film

Ag ion reacted with H2S gas in polyelectrolyte multilayer film to form Ag2S nanoparticles that catalyze the formation of Ag NPs.

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Enzyme-triggeredin situformation of Ag nanoparticles with oxidase-mimicking activity for amplified detection of alkaline phosphatase activity

The Analyst ◽

10.1039/c9an00105k ◽

2019 ◽

Vol 144 (7) ◽

pp. 2416-2422 ◽

Cited By ~ 25

Author(s):

Hongwei Song ◽

Zhibo Li ◽

Yinxian Peng ◽

Xin Li ◽

Xuechao Xu ◽

...

Keyword(s):

Alkaline Phosphatase ◽

Phosphatase Activity ◽

Alkaline Phosphatase Activity ◽

Ag Nanoparticles ◽

Colorimetric Detection ◽

Ag Nps

ALP-triggeredin situformation of Ag NPs with high oxidase-mimicking activity for colorimetric detection of alkaline phosphatase activity.

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Synthesis, Characterization and Antibacterial Activity of Ag/PVA Nanocomposite

Journal of Scientific Research ◽

10.3329/jsr.v5i1.11828 ◽

2012 ◽

Vol 5 (1) ◽

pp. 151-160 ◽

Cited By ~ 1

Author(s):

H. H. Saleh ◽

D. E. El-hadedy ◽

G. A. Meligi ◽

T. A. Afify

Keyword(s):

Antibacterial Activity ◽

Ag Nanoparticles ◽

Pathogenic Bacteria ◽

Pharmaceutical Products ◽

Poly Vinyl Alcohol ◽

X Ray Diffraction ◽

Ag Nps ◽

Transmission Electron ◽

Infection Treatment

Synthesis and characterization of Ag/PVA nanocomposite and comparison of its anti-bacterial activity with bacteriocin (nisin) for some pathogenic bacteria was carried out. Applications of the bacteriocin include dental care products, pharmaceutical products such as stomach ulcers, colon infection treatment and potential birth control. Ag/PVA nanocomposite was prepared by in situ reduction method, in which silver nitrate, gamma irradiation and poly(vinyl alcohol) (PVA) act as precursor, reductant and stabilizer, respectively. The synthesized Ag nanoparticles (Ag-Nps) have potential antibacterial activity toward both Gram-positive and Gram-negative bacteria. Further studies by X-ray diffraction (XRD) and transmission electron microscopy (TEM) have demonstrated the structure and the distribution of Ag nanoparticles caped within PVA polymer chain.© 2013 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.doi: http://dx.doi.org/10.3329/jsr.v5i1.11828 J. Sci. Res. 5 (1), 151-160 (2013)

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Multifunctional Hydroxyapatite/Silver Nanoparticles/Cotton Gauze for Antimicrobial and Biomedical Applications

Nanomaterials ◽

10.3390/nano11020429 ◽

2021 ◽

Vol 11 (2) ◽

pp. 429

Author(s):

Mohamed M. Said ◽

Mohamed Rehan ◽

Said M. El-Sheikh ◽

Magdy K. Zahran ◽

Mohamed S. Abdel-Aziz ◽

...

Keyword(s):

Biomedical Applications ◽

Antimicrobial Activities ◽

Uv Protection ◽

Hydroxyapatite Nanoparticles ◽

Ag Nps ◽

Cotton Gauze ◽

Cationic Modification ◽

Medical Textiles ◽

Anti Inflammation

Medical textiles have played an increasingly important protection role in the healthcare industry. This study was aimed at improving the conventional cotton gauze for achieving advanced biomedical specifications (coloration, UV-protection, anti-inflammation, and antimicrobial activities). These features were obtained by modifying the cotton gauze fabrics via in-situ precipitation of hydroxyapatite nanoparticles (HAp NP), followed by in-situ photosynthesis of silver (Ag) NPs with ginger oil as a green reductant with anti-inflammation properties. The HAp-Ag NPs coating provides good UV-protection properties. To further improve the HAp and Ag NPs dispersion and adhesion on the surface, the cotton gauze fabrics were modified by cationization with chitosan, or by partial carboxymethylation (anionic modification). The influence of the cationic and anionic modifications and HAp and Ag NPs deposition on the cotton gauze properties (coloration, UV-protection, antimicrobial activities, and water absorption) was thoroughly assessed. Overall, the results indicate that chemical (anionic and cationic) modification of the cotton gauze enhances HAp and Ag NPs deposition. Chitosan can increase biocompatibility and promotes wound healing properties of cotton gauze. Ag NP deposition onto cotton gauze fabrics brought high antimicrobial activities against Candida albicans, Gram-positive and Gram-negative bacteria, and improved UV protection.

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