Environmental Science: Atmospheres at one year

AbstractWe aimed to develop two models to estimate first AMI and stroke/TIA, respectively, in type 2 diabetes mellitus patients, by applying backward elimination to the following variables: age, sex, duration of diabetes, smoking, BMI, and use of antihyperglycemic drugs, statins, and aspirin. As time-varying covariates, we analyzed blood pressure, albuminuria, lipid profile, HbA1c, retinopathy, neuropathy, and atrial fibrillation (only in stroke/TIA model). Both models were stratified by antihypertensive drugs. We evaluated 2980 patients (52.8% women; 67.3 ± 11.2 years) with 24,159 person-years of follow-up. We recorded 114 cases of AMI and 185 cases of stroke/TIA. The factors that were independently associated with first AMI were age (≥ 75 years vs. < 75 years) (p = 0.019), higher HbA1c (> 64 mmol/mol vs. < 53 mmol/mol) (p = 0.003), HDL-cholesterol (0.90–1.81 mmol/L vs. < 0.90 mmol/L) (p = 0.002), and diastolic blood pressure (65–85 mmHg vs. < 65 mmHg) (p < 0.001). The factors that were independently associated with first stroke/TIA were age (≥ 75 years vs. < 60 years) (p < 0.001), atrial fibrillation (first year after the diagnosis vs. more than one year) (p = 0.001), glomerular filtration rate (per each 15 mL/min/1.73 m2 decrease) (p < 0.001), total cholesterol (3.88–6.46 mmol/L vs. < 3.88 mmol/L) (p < 0.001), triglycerides (per each increment of 1.13 mmol/L) (p = 0.031), albuminuria (p < 0.001), neuropathy (p = 0.01), and retinopathy (p = 0.023).

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Mortality in older adults following a fragility fracture: real-world retrospective matched-cohort study in Ontario

BMC Musculoskeletal Disorders ◽

10.1186/s12891-021-03960-z ◽

2021 ◽

Vol 22 (1) ◽

Cited By ~ 2

Author(s):

Jacques P. Brown ◽

Jonathan D. Adachi ◽

Emil Schemitsch ◽

Jean-Eric Tarride ◽

Vivien Brown ◽

...

Keyword(s):

Cohort Study ◽

Hip Fracture ◽

Fragility Fracture ◽

Mortality Risk ◽

Real World ◽

First Year ◽

Matched Cohort ◽

Matched Cohort Study ◽

Fracture Cohort ◽

One Year

Abstract Background Recent studies are lacking reports on mortality after non-hip fractures in adults aged > 65. Methods This retrospective, matched-cohort study used de-identified health services data from the publicly funded healthcare system in Ontario, Canada, contained in the ICES Data Repository. Patients aged 66 years and older with an index fragility fracture occurring at any osteoporotic site between 2011 and 2015 were identified from acute hospital admissions, emergency and ambulatory care using International Classification of Diseases (ICD)-10 codes and data were analyzed until 2017. Thus, follow-up ranged from 2 years to 6 years. Patients were excluded if they presented with an index fracture occurring at a non-osteoporotic fracture site, their index fracture was associated with a trauma code, or they experienced a previous fracture within 5 years prior to their index fracture. This fracture cohort was matched 1:1 to controls within a non-fracture cohort by date, sex, age, geography and comorbidities. All-cause mortality risk was assessed. Results The survival probability for up to 6 years post-fracture was significantly reduced for the fracture cohort vs matched non-fracture controls (p < 0.0001; n = 101,773 per cohort), with the sharpest decline occurring within the first-year post-fracture. Crude relative risk of mortality (95% confidence interval) within 1-year post-fracture was 2.47 (2.38–2.56) in women and 3.22 (3.06–3.40) in men. In the fracture vs non-fracture cohort, the absolute mortality risk within one year after a fragility fracture occurring at any site was 12.5% vs 5.1% in women and 19.5% vs 6.0% in men. The absolute mortality risk within one year after a fragility fracture occurring at a non-hip vs hip site was 9.4% vs 21.5% in women and 14.4% vs 32.3% in men. Conclusions In this real-world cohort aged > 65 years, a fragility fracture occurring at any site was associated with reduced survival for up to 6 years post-fracture. The greatest reduction in survival occurred within the first-year post-fracture, where mortality risk more than doubled and deaths were observed in 1 in 11 women and 1 in 7 men following a non-hip fracture and in 1 in 5 women and 1 in 3 men following a hip fracture.

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Across the COVID-19 Waves; Assessing Temporal Fluctuations in Perceived Stress, Post-Traumatic Symptoms, Worry, Anxiety and Civic Moral Disengagement over One Year of Pandemic

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18115651 ◽

2021 ◽

Vol 18 (11) ◽

pp. 5651

Author(s):

Alessio Gori ◽

Eleonora Topino

Keyword(s):

Perceived Stress ◽

State Anxiety ◽

Moral Disengagement ◽

Online Survey ◽

Well Being ◽

First Year ◽

Effective Interventions ◽

Post Traumatic ◽

One Year ◽

Traumatic Symptoms

This study aimed at investigating the psychological effect of the COVID-19 pandemic in Italy by analysing the trends of perceived stress, post-traumatic symptoms, state anxiety, worry, and civic moral disengagement in four different moments from March 2020 to March 2021. The study involved a total of 1827 Italian participants (30% men and 70% women; Mage = 34.72; SD = 12.40) divided into four groups to which an online survey was administered. The first group completed the survey in March 2020, the second one in August 2020, the third one in November 2020, and the fourth one in March 2021. Results highlighted significant decreases in post-traumatic symptoms and a significant increase in civic moral disengagement over the first year of the COVID-19 pandemic. The levels of perceived stress, worry, and state anxiety remained constant. The correlations between the variables at different times were also explored, as well as gender differences over the year. The COVID-19 emergency has had significant effects on the mental state of the population, with important repercussions for individual and collective well-being during but probably also after the pandemic. This study offers a clear snapshot of the psychological outcomes over one COVID-19 pandemic year, providing important information that may contribute to tailor more effective interventions for mental health.

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Teething Symptoms in the First Year of Life and Associated Factors: A Cohort Study

Journal of Clinical Pediatric Dentistry ◽

10.17796/jcpd.34.3.h318882h52616225 ◽

2010 ◽

Vol 34 (3) ◽

pp. 201-206 ◽

Cited By ~ 7

Author(s):

Carlos Alberto Feldens ◽

Italo Medeiros Faraco Junior ◽

Andréia Bertani Ottoni ◽

Eliane Gerson Feldens ◽

Márcia Regina Vítolo

Keyword(s):

Associated Factors ◽

Primary Outcome ◽

First Year ◽

Structured Interviews ◽

Self Medication ◽

Nuclear Families ◽

Dental Examination ◽

Pediatric Dentists ◽

One Year ◽

First Year Of Life

Objective: To investigate the occurrence and management of teething symptoms during the first year of life and associated factors. Study design: 500 children were recruited at birth. Research assessments including structured interviews, anthropometric measurements and dental examination were carried out after birth, at 6 months and at one-year of age. The primary outcome of this study was defined as the occurrence of one or more teething symptoms within the first year of life, as reported by the mother. Results: Teething symptoms were reported in 73% of the children analyzed (273/375). The symptoms most frequently reported were irritability (40.5%), fever (38.9%), diarrhoea (36.0%) and itching (33.6%). Dentists had little influence on the management of symptoms and self-medication to relieve them was a common practice. The risk of reporting teething symptoms was higher for children from nuclear families (p=0.040) and for children from families with higher income (p=0.040). Conclusions: Teething symptoms were highly reported in this population. Pediatric dentists should be accessible and provide adequate orientation when symptoms can be managed at home or immediate referral to health services when more serious diseases are suspected.

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Partnership in Post-Adoption Services Evaluating the First Year of a Complementary Contract

Adoption & Fostering ◽

10.1177/030857599702100308 ◽

1997 ◽

Vol 21 (3) ◽

pp. 50-56 ◽

Cited By ~ 1

Author(s):

Alan Burnell ◽

Adrian Briggs

Keyword(s):

Social Services ◽

Comprehensive Assessment ◽

First Year ◽

Service Users ◽

Adoptive Families ◽

Treatment Services ◽

Assessment And Treatment ◽

One Year ◽

Families With Children ◽

Consultation Services

In the autumn 1995 edition of Adoption & Fostering, Alan Burnell and Adrian Briggs described the origins and objectives of a novel complementary contract between East Sussex Social Services and the Post-Adoption Centre (PAC), aimed at providing post-adoption counselling and consultation services to all those involved in adoption in the county. The same authors now evaluate the operation of the contract, one year on. After filling in some background they assess its achievements so far, with particular regard to the extra support to service users and staff, and reducing the risk of disruption. The article concludes that the first year of the contract has demonstrated the need for comprehensive assessment and treatment services for adoptive families with children experiencing attachment difficulties.

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Environmental Science: Nano – the first year a successful launch

Environmental Science Nano ◽

10.1039/c4en90025a ◽

2015 ◽

Vol 2 (1) ◽

pp. 9-10

Author(s):

Vicki H. Grassian

Keyword(s):

Environmental Science ◽

First Year ◽

Successful Launch

Editor-in-Chief Vicki H. Grassian introduces the second volume of Environmental Science: Nano.

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ADENOVIRUS COMPLEMENT-FIXING ANTIBODY TITERS FROM BIRTH THROUGH THE FIRST YEAR OF LIFE

PEDIATRICS ◽

10.1542/peds.32.4.497 ◽

1963 ◽

Vol 32 (4) ◽

pp. 497-500

Author(s):

Rosa Lee Nemir ◽

Donna O'Hare ◽

Stanley Goldstein ◽

Charles B. Hilton

Keyword(s):

Cytopathic Effect ◽

Gradual Increase ◽

Newborn Infants ◽

First Year ◽

Placental Barrier ◽

Culture Studies ◽

Antibody Titers ◽

Level 1 ◽

One Year ◽

First Year Of Life

Complement fixing antibody titers to the adenoviruses were determined in 251 newborn infants, using cord blood. Approximately 95% of these were found to have CF titers of 1:16 or over, the majority (75%) were 1:32 or more. Material from the pharyngeal and rectal swabs of these infants on tissue culture studies (542) on HeLa and amnion cells showed no cytopathic effect in oven 96% of these infants. A longitudinal study of 114 of these infants was made at 3 months intervals; 67 have been observed for one year. At 3 months, only 12% still showed CF antibody titers, and these were chiefly at a low level, 1:16. At the subsequent 3-month interval observations, a gradual rise in CF antibodies were found. At one year of age, approximately 37% had titers of 1:32 on over. The findings of this report support the statement that CF antibodies to adenovirus pass the placental barrier. There is a gradual increase in the percentage of infants with positive CF antibodies after 3 months.

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Mentorship program in a tertiary care private medical college of Eastern India: evaluation, appraisal and recommendations (Preprint)

10.2196/preprints.28194 ◽

2021 ◽

Author(s):

Dipmala Das ◽

Asitava Deb Roy ◽

Alka Rawekar

Keyword(s):

Analytical Study ◽

Tertiary Care ◽

First Year ◽

Eastern India ◽

Mentorship Program ◽

Medical College ◽

Validated Questionnaire ◽

Mentorship Programs ◽

One Year ◽

Strongly Agree

BACKGROUND Mentorship programs are becoming increasingly common in undergraduate medical education all over the world. However, very few medical colleges are running mentorship programs in India. A mentorship program was introduced in our college for the first year MBBS students to help them cope up with the stress of the new environment. OBJECTIVE The aim of this study is to evaluate the mentorship program with regard to its efficacy, utility, limitation and potential for improvement after successful completion of one year of the program. METHODS It was an observational analytical study including 143 mentees and 15 mentors conducted in a tertiary care teaching hospital for five months from November 2019 to March 2020. Two sessions of FGD were carried out involving 7 students in each session. One session of FGD was conducted involving 7 mentors. The feedback was collected with a pre validated questionnaire containing 10 questions (8 close ended and 2 open ended). Feedback of closed ended questions were obtained by using a 5-point Likert scale (1 to 5) where 5 indicated ‘Strongly Agree’ and 1 indicated ‘Strongly Disagree’ RESULTS Most of the mentees (86.7%) and mentors (66.7%) mentioned that mentorship program is necessary for the welfare of the students. However, it was also noted that better communication and frequent meetings can improve the outcome of the program. CONCLUSIONS Mentorship program is deemed essential, however, a well-structured framework and dedicated time from both mentors and mentees will make the program more successful. This type of feedback evaluation is however important to validate such program.

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Use of Trained Mothers to Teach Interviewing Skills to First-Year Medical Students: A Follow-up Study

PEDIATRICS ◽

10.1542/peds.60.2.165 ◽

1977 ◽

Vol 60 (2) ◽

pp. 165-169 ◽

Cited By ~ 1

Author(s):

Paula L. Stillman ◽

Darrell L. Sabers ◽

Doris L. Redfield

Keyword(s):

Medical Students ◽

School Curriculum ◽

Control Group ◽

First Year ◽

Feedback Session ◽

Optimal Learning ◽

Interviewing Skills ◽

One Year ◽

First Year Medical Students

This report describes an attempt to evaluate the effectiveness of "trained mother" interviews early in the medical school curriculum. As an adjunct to a first-year course that teaches interviewing techniques, half of the students were exposed to an interview with one of three trained mothers early in the course. This treatment interview was immediately followed by a feedback session which concentrated on the content and process of interviewing. At the end of the course, all students had an evaluative interview. Those students who had an initial interview and feedback session with a trained mother scored significantly higher on both the content and process of their interviews than the control group. This technique is an effective and efficient way to teach interviewing skills to medical students prior to entering any of their clinical clerkships. A follow-up assessment conducted one year later indicated that one interview with a trained mother is sufficient for optimal learning and that the skills learned are retained over at least that period of time.

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Immunity to Diphtheria, Pertussis, Tetanus, and Poliomyelitis in Children with Acute Lymphocytic Leukemia After Cessation of Chemotherapy

PEDIATRICS ◽

10.1542/peds.67.2.222 ◽

1981 ◽

Vol 67 (2) ◽

pp. 222-229 ◽

Cited By ~ 1

Author(s):

A. van der Does-van den Berg ◽

J. Hermans ◽

J. Nagel ◽

G. van Steenis

Keyword(s):

Acute Lymphocytic Leukemia ◽

Lymphocytic Leukemia ◽

First Year ◽

Healthy Children ◽

Healthy Control ◽

Antibody Titers ◽

Group A ◽

One Year ◽

Group B ◽

Antibody Levels

Antibody titers to diphtheria, pertussis, tetanus, and poliomyelitis (types I to III) were measured in previously vaccinated children with acute lymphocytic leukemia in remission after cessation of therapy. The response to revaccination one year after therapy was stopped was also studied. The patients' antibody titers were compared with those of healthy children, matched for age and sex. Two groups of patients were studied: one group (group A, N = 30) was given two drugs (6-mercaptopurine, methotrexate); the other group (group B, N= 19) was given three drugs (6-mercaptopurine, methotrexate, and cyclophosphamide) for maintenance treatment. In general, the patients' antibody titers were lower than those of healthy children, but in most patients they were still at levels considered to be protective. No significant differences in antibody levels between the two patient groups were found. A spontaneous rise in antibody titers in the first year after termination of therapy was not observed. After revaccination the rise in antibody titers was correlated with preexisting antibody titers in the same way in patients as in healthy children, and the antibody titers in patients and in healthy control subjects were on roughly the same level.

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