Rates of New Bone Formation in Patients with Crush Fracture Osteoporosis

1982 ◽  
Vol 63 (2) ◽  
pp. 153-160 ◽  
Author(s):  
J. Reeve ◽  
J. R. Green ◽  
R. Hesp ◽  
Patricia Hulme
Keyword(s):  
Bone Resorption ◽  
Bone Formation ◽  
Accretion Rate ◽  
Positive Association ◽  
Calcium Balance ◽  
Tracer Technique ◽  
New Bone Formation ◽  
True Rate ◽  
Exchange Processes

1. Calcium balances and formation rates of new bone measured with an improved tracer technique using 85Sr have been determined simultaneously in 21 patients with idiopathic osteoporosis and vertebral crush fractures. 2. A weak positive association was found between calcium balance and the kinetically measured calcium accretion rate, which is the sum of the true rate of bone formation and various long-term exchange processes. 3. The more negative balances were associated with significantly greater early loss of tracer taken up into bone by ‘accretion’, so that long-term (> 200 day) uptake was reduced. 4. This indicates that patients actively losing bone mineral have lower true rates of bone formation and higher rates of long-term exchange than their fellow patients who are more nearly in calcium equilibrium. 5. No statistically significant association was found between measured rates of bone resorption and calcium balance.

Changes in bone metabolism associated with exposure to industrial vibration

2020 ◽  
pp. 766-766
Author(s):  
A. V. Sukhova ◽  
E. N. Kryuchkova
Keyword(s):  
Bone Mineral Density ◽  
Alkaline Phosphatase ◽  
Bone Resorption ◽  
Bone Formation ◽  
Bone Metabolism ◽  
Biochemical Markers ◽  
Mineral Density ◽  
Local Vibration ◽  
Markers Of Bone Formation

The influence of general and local vibration on bone remodeling processes is investigated. The interrelations between the long - term exposure of industrial vibration and indicators of bone mineral density (T-and Z-criteria), biochemical markers of bone formation (osteocalcin, alkaline phosphatase) and bone resorption (ionized calcium, calcium/creatinine) were established.

Strontium delivery on topographical titanium to enhance bioactivity and osseointegration in osteoporotic rats

2015 ◽  
Vol 3 (24) ◽  
pp. 4790-4804 ◽  
Author(s):  
Jin Wen ◽  
Jinhua Li ◽  
Hongya Pan ◽  
Wenjie Zhang ◽  
Deliang Zeng ◽  
...  
Keyword(s):  
Bone Resorption ◽  
Bone Formation ◽  
New Bone Formation

Strontium-substituted hierarchical Ti surface can enhance the osseointegration by both increasing new bone formation and reducing bone resorption under osteoporotic conditions.

scholarly journals Long-term reaction to bone cement in osteoporotic bone: new bone formation in vertebral bodies after vertebroplasty

2008 ◽  
Vol 212 (5) ◽  
pp. 697-701 ◽  
Author(s):  
Volker Braunstein ◽  
Christoph M. Sprecher ◽  
Armando Gisep ◽  
Lorin Benneker ◽  
Kathrin Yen ◽  
...  
Keyword(s):  
Bone Formation ◽  
Bone Cement ◽  
Osteoporotic Bone ◽  
New Bone Formation ◽  
Vertebral Bodies

Long-Term Tissue Reactions of Three Biomaterials in Craniofacial Surgery

2007 ◽  
Vol 361-363 ◽  
pp. 1343-1346 ◽  
Author(s):  
Matti Peltola ◽  
Kalle Aitasalo ◽  
Teemu Tirri ◽  
Jami Rekola ◽  
A. Puntala
Keyword(s):  
Bone Formation ◽  
Close Contact ◽  
Healing Process ◽  
Tissue Growth ◽  
Bovine Bone ◽  
New Bone Formation ◽  
Electron Microscopic ◽  
Composition Profiles ◽  
Tissue Reactions

Successful craniofacial reconstruction needs both a well-known and a reliable reconstruction material. However, there is often a lack of long-term knowledge of the tissue reactions and healing process in the human body. In this study, frontal sinus obliterations with bovine bone natural hydroxyapatite derivative (BHA), synthetic bioactive glass S53P4 (BAG) and hydroxyapatite cement (HAC) were investigated with clinical, histologic, scanning electron microscopic (SEM) and energy dispersive x-ray analysis (EDXA) 27, 12 and 3 years postoperatively. The aim was to determine the long-term clinical biocompatibility of the used materials. Histologic studies revealed bone formation with BHA particles and lamellar bone with BAG granule remnants in close contact to the new bone formation. In HAC reconstruction there was scattered fibroconnective tissue growth without new bone formation in the surface of HAC implantation. Neither foreign body reaction nor any abnormal findings were seen. SEM studies revealed a CaP layer on the surface of BAG granule remnants. In EDXA studies, composition profiles showed Ca-, P- and Si- rich layers on the BAG granule surface. No differences were found in CaO and P2O5 levels between BHA granules and HAC implantation and the surrounding bone. All investigated biomaterials were well tolerated in long-term applications.

scholarly journals SCREENING FOR VIETNAMESE PLANT EXTRACTS WITH POTENTIAL BENEFIT FOR ANTI OSTEOCLASTOGENESISH

2021 ◽  
Vol 59 (4) ◽  
pp. 507
Author(s):  
Hai Dang Nguyen ◽  
Thanh Huong Le ◽  
Thu Trang Duong
Keyword(s):  
Side Effects ◽  
Bone Resorption ◽  
Bone Formation ◽  
Plant Extracts ◽  
Potential Benefit ◽  
Mouse Macrophage ◽  
Potential Source ◽  
Inhibitory Activities ◽  
First Time

Bone's homeostasis is only achieved when there is a balance between bone formation and bone resorption. A metabolic disorder of bone-resorbing osteoclasts can lead to osteoporosis. Long-term use of anti-osteoporosis drugs can lead to undesirable side effects so traditional herbal can be a potential source of alternative medicine. In the present study, forty one Vietnamese plants (seventy methanol extracts) were screened for osteoclastogenesis inhibitory activities on RAW264.7 mouse macrophage cells. For the first time, 29 extracts from 24 species showed potential as effective inhibitors of osteoclastogenesis.

Type II Collagen-Induced Autoimmune Otospongiosis

1983 ◽  
Vol 92 (2) ◽  
pp. 103-108 ◽  
Author(s):  
T. J. Yoo ◽  
K. Tomoda ◽  
A. H. Kang ◽  
J. M. Stuart ◽  
A. S. Townes
Keyword(s):  
Bone Resorption ◽  
Bone Formation ◽  
Bone Matrix ◽  
Type Ii Collagen ◽  
Antibody Responses ◽  
Type Ii ◽  
New Bone Formation ◽  
Chemical Alteration ◽  
Immunofluorescence Studies ◽  
Dark Staining

Otospongiosis-like lesions were induced in rats by immunizing them with native type II collagen. Immunized rats had antibody responses specific for native type II collagen and developed otospongiosis-like lesions. The spongiotic lesion was characterized by numerous osteocytes and osteoblasts in the vascular spaces and by dark staining probably due to the chemical alteration of ground substances. Bone resorption and new bone formation were clearly visible. Immunofluorescence studies demonstrated deposition of immunoglobulin and complement on the bone matrix and wall within the area of spongiosis. An antibody-mediated etiopathogenesis was suspected.

Bone Formation in Psoriatic Arthritis: A Report from the GRAPPA 2013 Annual Meeting

2014 ◽  
Vol 41 (6) ◽  
pp. 1218-1219 ◽  
Author(s):  
Georg Schett
Keyword(s):  
Rheumatoid Arthritis ◽  
Psoriatic Arthritis ◽  
Bone Resorption ◽  
Bone Formation ◽  
Annual Meeting ◽  
Simultaneous Presence ◽  
New Bone Formation ◽  
Bone Erosions

The simultaneous presence of bone erosions and bony spurs (osteophytes, enthesophytes) in the joints of patients with psoriatic arthritis (PsA) suggests that the disease leads to enhanced bone resorption as well as increased bone formation, the latter of which has not been observed in patients with rheumatoid arthritis. At the 2013 Annual Meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), members heard an update on the current research into the cytokine signature in PsA and its effects on new bone formation.

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