scholarly journals Phytochemical analysis and antioxidant assay of Melissa officinalis L. (lemon balm)

2021 ◽  
Vol 40 ◽  
pp. 02004
Author(s):  
Lidia-Ioana Virchea ◽  
Felicia Gabriela Gligor ◽  
Adina Frum ◽  
Monica Mironescu ◽  
Nina I. Myachikova ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Acids ◽  
Volatile Oil ◽  
Antioxidant Compounds ◽  
Phytochemical Analysis ◽  
Melissa Officinalis ◽  
Lemon Balm ◽  
Beneficial Effects ◽  
Aerial Parts ◽  
Popular Language

Melissa officinalis L. called in popular language lemon balm is a medicinal plant belonging to the Lamiaceae family. The plant contains a variety of bioactive compounds among which volatile oils, flavonoids and phenolic acids. These are responsible for a lot of beneficial effects in disease relief. Lemon balm has antioxidant, antimicrobial, neuroprotective, anxiolytic, spasmolytic and other effects. Important for its antioxidant activity are flavonoids and phenolic acids which are well known for their ability to scavenge the free radicals. Due to this effect, lemon balm protects against the development of degenerative diseases such as Alzheimer’s disease, cardiovascular disease, cancer and dermatological disorders. In this study we extracted and determined the content of the volatile oil and flavonoids from Melissa officinalis L. and we investigated the antioxidant activity of an extract obtained from dried aerial parts of lemon balm. The results showed that the volatile oil content was low (0.17 mL/100 g vegetal material). The total flavonoid content was 0.965 g rutoside/100 g of vegetal product and the antioxidant activity was 90.40 %. From this study, we concluded that Melissa officinalis L. is a potential source of antioxidant compounds with a lot of other benefits for human health.

scholarly journals Brewing By-Product Upcycling Potential: Nutritionally Valuable Compounds and Antioxidant Activity Evaluation

Antioxidants ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 165
Author(s):  
Elisabetta Bravi ◽  
Giovanni De Francesco ◽  
Valeria Sileoni ◽  
Giuseppe Perretti ◽  
Fernanda Galgano ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Acids ◽  
Liquid Waste ◽  
Value Added ◽  
Total Phenolic ◽  
Antioxidant Compounds ◽  
Brewing Industry ◽  
Antioxidant Power ◽  
Spent Grains ◽  
By Products

The brewing industry produces high quantities of solid and liquid waste, causing disposal issues. Brewing spent grains (BSGs) and brewing spent hop (BSH) are important by-products of the brewing industry and possess a high-value chemical composition. In this study, BSG and BSH, obtained from the production process of two different types of ale beer (Imperial red and Belgian strong beer) were characterized in terms of valuable components, including proteins, carbohydrates, fat, dietary fiber, β-glucans, arabinoxylans, polyphenols, and phenolic acids, and antioxidant activity (Ferric Reducing Antioxidant Power Assay (FRAP), 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-Azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS)). Significant concentrations of total polyphenols were observed in both BSH and BSG samples (average of about 10 mg GAE/g of dry mass); however, about 1.5-fold higher levels were detected in by-products of Belgian strong ale beer compared with Imperial red. Free and bound phenolic acids were quantified using a validated chromatographic method. A much higher level of total phenolic acids (TPA) (about 16-fold higher) was found in BSG samples compared with BSHs. Finally, their antioxidant potential was verified. By-products of Belgian strong ale beer, both BSG and BSH, showed significantly higher antioxidative capacity (about 1.5-fold lower inhibitory concentration (IC50) values) compared with spent grains and hop from the brewing of Imperial red ale. In summary, BSG and BSH may be considered rich sources of protein, carbohydrates, fiber, and antioxidant compounds (polyphenols), and have the potential to be upcycled by transformation into value-added products.

scholarly journals Effects of Drying Temperature on Antioxidant Activity of Lemon Balm (Melissa officinalis) Leaves

2008 ◽  
Vol 55 (6) ◽  
pp. 293-298 ◽  
Author(s):  
Chizuko Yukizaki ◽  
Miho Sakai ◽  
Taeko Kosaka ◽  
Masumi Dozono ◽  
Masanobu Sakono ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Melissa Officinalis ◽  
Lemon Balm ◽  
Drying Temperature

scholarly journals Antioxidant Principles of Tanacetum vulgare L. Aerial Parts

2009 ◽  
Vol 4 (11) ◽  
pp. 1934578X0900401 ◽  
Author(s):  
Malindra Juan-Badaturuge ◽  
Solomon Habtemariam ◽  
Caroline Jackson ◽  
Michael JK Thomas
Keyword(s):  
Antioxidant Activity ◽  
Crude Extract ◽  
Radical Scavenging ◽  
Major Constituent ◽  
Antioxidant Compounds ◽  
Rheumatic Arthritis ◽  
Tanacetum Vulgare ◽  
Medicinal Uses ◽  
Inflammatory Conditions ◽  
Aerial Parts

The methanolic extract of aerial parts of Tanacetum vulgare L. (Asteraceae) and its fractions were investigated for antioxidant activity. The crude extract displayed DPPH radical scavenging effects with an EC50 value of 37 ± 1.2 μg/mL (n=3). Activity-guided fractionations of the crude extract resulted in the isolation of three antioxidant compounds; 3,5-O-dicaffeoylquinic acid (3,5-DCQA), axillarin and luteolin. 3,5-DCQA was the major constituent with antioxidant activity (IC50 = 9.7 μM) comparable with that of the standard quercetin (IC50 = 8.8 μM). Though the isolated compounds were previously known for their antioxidant effects, this is the first report on the identification of 3,5-DCQA from Tanacetum vulgare. The displayed potent antioxidant activity of the crude extract and isolated active principles is in support of the traditional medicinal uses of the plant for disease conditions such as wound healing, rheumatic arthritis and other inflammatory conditions.

Flavonoids and Phenolic Acids in Methanolic Extracts, Infusions and Tinctures from Commercial Samples of Lemon Balm

2015 ◽  
Vol 10 (6) ◽  
pp. 1934578X1501000 ◽  
Author(s):  
Agnieszka Arceusz ◽  
Marek Wesolowski ◽  
Beata Ulewicz-Magulska
Keyword(s):  
Phenolic Compounds ◽  
Phenolic Acids ◽  
Principal Component ◽  
Hierarchical Cluster ◽  
Dry Weight ◽  
Melissa Officinalis ◽  
Lemon Balm ◽  
Biochemical Pathways ◽  
Methanolic Extracts ◽  
Principal Component Analyses

The aim of this study was to quantify the levels of flavonoids (rutin, myricetin, quercetin, kaempferol) and phenolic acids (gallic, p-coumaric, rosmarinic, syringic, caffeic, chlorogenic, ellagic, ferulic) in lemon balm ( Melissa officinalis L.) commonly used as a culinary, aromatic and medicinal herb. A rapid and reliable HPLC procedure was developed to determine the phenolic compounds in methanolic extracts, infusions and tinctures prepared from lemon balm. Except for myricetin and quercetin, as well as ellagic, gallic and rosmarinic acids, higher levels of the analytes under study were determined in the methanolic extracts (up to 22 mg/g of dry weight, DW), than in infusions (up to 5 mg/g DW). Tinctures were the poorest in flavonoids and phenolic acids (below 550 μg/g DW), except for ellagic and rosmarinic acids, which were quantified in tinctures at higher levels (mg/g DW). To sum up, the flavonoids were extracted more effectively in the infusions and tinctures than the phenolic acids. Statistically significant correlations were found between phenolic acids, possibly owing to similar biochemical pathways of the compounds. The hierarchical cluster and principal component analyses have also shown that the samples of lemon balm could be differentiated based on the levels of flavonoids and phenolic acids.

scholarly journals Grapevine as a Rich Source of Polyphenolic Compounds

Molecules ◽  
2020 ◽  
Vol 25 (23) ◽  
pp. 5604
Author(s):  
Iva Šikuten ◽  
Petra Štambuk ◽  
Željko Andabaka ◽  
Ivana Tomaz ◽  
Zvjezdana Marković ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Secondary Metabolites ◽  
Human Health ◽  
Phenolic Acids ◽  
Polyphenolic Compounds ◽  
Wine Quality ◽  
Primary And Secondary Metabolites ◽  
Grape Berries ◽  
Beneficial Effects ◽  
Grape Varieties

Grapes are rich in primary and secondary metabolites. Among the secondary metabolites, polyphenolic compounds are the most abundant in grape berries. Besides their important impacts on grape and wine quality, this class of compounds has beneficial effects on human health. Due to their antioxidant activity, polyphenols and phenolic acids can act as anti-inflammatory and anticancerogenic agents, and can modulate the immune system. In grape berries, polyphenols and phenolic acids can be located in the pericarp and seeds, but distribution differs considerably among these tissues. Although some classes of polyphenols and phenolic acids are under strict genetic control, the final content is highly influenced by environmental factors, such as climate, soil, vineyard, and management. This review aims to present the main classes of polyphenolic compounds and phenolic acids in different berry tissues and grape varieties and special emphasis on their beneficial effect on human health.

scholarly journals Historical Course of Neuropsychiatric Effects of Lemon Balm (Melissa Officinalis L.) as a Medicinal Herb

2021 ◽  
Author(s):  
Javid Ghazizadeh ◽  
Reza Mohammadinasab ◽  
Nikolaj Travica ◽  
Saeed Sadigh-Eteghad ◽  
Mohammadali Torbati ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Middle Ages ◽  
Neuropsychiatric Disorders ◽  
Therapeutic Effects ◽  
Depression And Anxiety ◽  
Melissa Officinalis ◽  
Lemon Balm ◽  
Beneficial Effects ◽  
15Th Century ◽  
History Of

Abstract Affective disorders have become prevalent and costly worldwide chronic conditions. Lemon Balm (Melissa Officinalis L.) is a medicinal plant with beneficial effects on neuropsychiatric disorders. Its potential to specifically treat conditions such as depression and anxiety has been investigated for over 20 centuries. Given the lack of a historical overview of lemon balm in mood disorders, the present review aimed to introduce the historical course of the neuro-psychiatric applications of lemon balm across the centuries. We investigated several viable medieval Arabic sources up to the 15th century, to distinguish the neuropsychiatric applications, especially anxiolytic and anti-depressive effects of lemon balm. In the early centuries, lemon balm was mainly prescribed to treat gastrointestinal disorders. Over time, physicians identified the efficient use of lemon balm in sadness, sleep disorders, anxiety, depression, epilepsy, ischemic stroke, amnesia, sciatalgia, and radicular neuropathy. Importantly, it was established that the therapeutic effects of lemon balm in the field of neuro-psychiatric diseases were emphasized by physicians during the Middle Ages. These findings have since been validated in human clinical trials. Lemon balm has also demonstrated the ability to be utilized in epilepsy, amnesia and ischemic stroke. Based on the extensive history of lemon balm in neuropsychiatry, future investigations could use this knowledge to extensively investigate the potential of lemon balm in neuropsychiatric disorders such as depression and anxiety, and possibly develop an efficient neuropsychiatric remedy.

scholarly journals The Economic Analysis of Semi-mechanised Harvesting of Lemon Balm

2016 ◽  
Vol 64 (1) ◽  
pp. 291-296
Author(s):  
Vladimír Mašán ◽  
Tomáš Kopta
Keyword(s):  
Economic Analysis ◽  
Purchase Price ◽  
Melissa Officinalis ◽  
Lemon Balm ◽  
Aerial Parts ◽  
Intensive Use ◽  
Effective Use

In recent years area for cultivation of Melissa officinalis is ranged around 40 ha. Low production could be also caused by less intensive use of machinery. Aerial parts could be fully harvested by mechanisation, but in case of small growers using of special machinery is not economic. The majority of growers harvest manually and this type of harvest represents up to 80% of the costs associated with the cultivation. The less expensive alternative of harvest by a hedge trimmer is evaluated in this article. The goal is to compare two ways of harvest (manual harvest and hedge trimmer harvest) of lemon balm aerial parts in production practise. According to results of experiments were calculated and determined boundaries of effective use of hedge trimmer in production of lemon balm in comparision to manual harvest and fully mechanised harvest. Obtained data shown an increase of harvest performance in case of hedge trimmer (0.0425–0.0525 ha.hr−1) compared to manual harvest (0.0185–0.0216 ha.hr−1). According to calculations, we can say that effective use of hedge trimmer (including purchase price) is from 0.37 ha at planting surface and 0.48 ha at planting rows. Results could also be used for other MAP crops with similar harvest technology as for lemon balm (for example Mentha spp., Origanum spp., Achillea spp.).

scholarly journals SANTALUM ALBUM;

2019 ◽  
Vol 26 (05) ◽  
Author(s):  
Sonia Gull ◽  
Asim Mushtaq ◽  
Muhammad Umer ◽  
Sajid Mehmood
Keyword(s):  
Antioxidant Activity ◽  
Antibacterial Activity ◽  
Medicinal Plants ◽  
Radical Scavenging ◽  
Antioxidant Compounds ◽  
Phytochemical Analysis ◽  
Santalum Album ◽  
Zone Of Inhibition ◽  
Staph Aureus ◽  
Lemon Grass

Medicinal plants are good alternate of antibiotics against many bacterial as well as other diseases. Santalum album (Sandal) and Cymbopogon (Lemon grass) are two important medicinal plants whose important components were extracted by sequential extraction from non-polar to polar solvents. The study was aimed at finding antibacterial and radical scavenging potential of Santalum album (Sandal) and Cymbopogon (Lemon grass). Study Design: In vitro study. Setting: Department of Biochemistry and Molecular Biology, University of Gujrat, Gujrat. Period: 12 months. Material and Methods: Sequential extracts of Santalum album and Cymbopogon with n-hexane, chloroform, acetone, ethylacetate, ethanol, butanol and water respectively were prepared to evaluate antibacterial activity against Staph aureus (25923), Staph aureus (38541), E.coli (25922), E.coli (35318), Streptococcus pyrogenes (Tc-11-2) and Shigella sonnei (BB-8). 2,2-Diphenyl-1-picrylhydrazyl (DPPH) was used to assess antioxidant activity. Results: Ethanolic and acetone extracts of sandal and lemongrass showed significant inhibtory activity against all seven strains. In case of sandal, acetone extract exhibited highest inhibitory activity against Staph aureus (25923) with 17±2 mm zone of inhibition while ethanolic extract of lemon grass showed highest activity with 16.333 ± 1.154mm zone of inhibition against E.Coli (35318). Other solvents including chloroform, n-hexane, ethyl acetate and butanol also showed considerable antibacterial activity, but water extracts of both plants showed no activity. All polarity based extracts of both plants exhibited antioxidant activity, ethanolic extracts of sandal and lemon grass showed highest radical scavenging activity with 84.366 ±1.504% and 83.766 ±4.272% inhibitions respectively. The minimum antioxidant activity was observed for chloroform extracts of sandal and n-hexane extract of lemongrass. Conclusion: we concluded that some plants have good antibacterial and antioxidant potential. Their phytochemical analysis can be carried out to find potent antibacterial and antioxidant compounds. This will be effective in combating bacterial diseases because mostly microbes are developing resistance against currently available antibiotics.

scholarly journals Evaluation of phytochemical and superoxide dismutase activities of Enhalus acoroides (L.f.) Royle from coastal waters of North Sulawesi, Indonesia

2020 ◽  
Vol 13 (4) ◽  
pp. 676-680
Author(s):  
Febry S. I. Menajang ◽  
Mohammad Mahmudi ◽  
Uun Yanuhar ◽  
Endang Yuli Herawati
Keyword(s):  
Antioxidant Activity ◽  
Superoxide Dismutase ◽  
Natural Antioxidants ◽  
Antioxidant Compounds ◽  
Beneficial Effects ◽  
Enhalus Acoroides ◽  
North Sulawesi ◽  
Antioxidant Agents ◽  
Phytochemical Constituents ◽  
Concentration Series

Background and Aim: Seagrasses are an excellent and potential bioresource to discover new natural bioactive compounds such as antioxidants that have beneficial effects on health. Natural antioxidants have many functions in biological systems, primarily for defense against oxidation which produces free radicals in food, chemicals, and living systems. This study aimed to discover new natural antioxidant agents, Enhalus acoroides (L.f.) Royle was evaluated for phytochemical constituents and the antioxidant activity against superoxide dismutase (SOD) was assessed. Materials and Methods: Sample specimens of E. acoroides (L.f.) Royle collected from two different areas, Manembo- Nembo, Bitung (SG-A) and Bahoi, Likupang Barat (SG-B) waters, were extracted with methanol and solutions were prepared in a concentration series. Results: Extracts of the seagrass E. acoroides (L.f.) Royle cultivated in different areas have different phytochemical constituents and SOD activities. The secondary metabolites of phenols, flavonoids, and steroids contained in the ethyl acetic extracts of E. acoroides were linearly correlated with their antioxidant activity, which exhibited an IC50 of 7 ppm. Conclusion: E. acoroides (L.f.) Royle samples cultivated in the two areas contained different phytochemical constituent profiles, indicating an effect of environmental factors, and both can be used as potential natural sources of antioxidant compounds.

scholarly journals Quantitative Analysis of Phenolic Acids and Antiplatelet Activity of Melissa officinalis Leaf Extracts

2017 ◽  
Vol 12 (1) ◽  
pp. 1934578X1701200 ◽  
Author(s):  
Željan Maleš ◽  
Andrea Antolić ◽  
Ivana Babić ◽  
Sandra Jurić ◽  
Mirza Bojić
Keyword(s):  
Statistical Analysis ◽  
Quantitative Analysis ◽  
Phenolic Acids ◽  
Rosmarinic Acid ◽  
Final Concentration ◽  
Total Phenolic ◽  
Antiplatelet Activity ◽  
Melissa Officinalis ◽  
Leaf Extracts ◽  
Lemon Balm

The contents of total phenolic acids and rosmarinic acid were determined and the antiplatelet potential assessed of extracts of lemon balm ( Melissa officinalis L., Lamiaceae) leaf samples collected during 2014 and 2015. The quantity of total phenolic acids ranged from 4.8 to 8.5%, while the rosmarinic acid content ranged from 1.78 to 4.35%. Results of statistical analysis showed that the undiluted extracts have antiplatelet activity in the ADP test (final concentration 31.25 mg/L). While there are reports on antiplatelet activity of lemon balm essential oil, to the best of our knowledge, this is the first report on antiplatelet activity of lemon balm leaf extracts.

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