scholarly journals Bacterial isolates from burn wound infections and their antibiograms: A eight-year study

2007 ◽  
Vol 40 (01) ◽  
pp. 91-93
Author(s):  
Mehta Manjula ◽  
Dutta Priya ◽  
Gupta Varsha
Keyword(s):  
Multi Drug Resistance ◽  
Resistance Pattern ◽  
Periodic Review ◽  
Bacterial Isolates ◽  
Burn Wound ◽  
Klebsiella Species ◽  
Acinetobacter Species ◽  
Bacteriological Profile ◽  
Pseudomonas Species ◽  
Burns Unit

ABSTRACT Background:Infection is an important cause of mortality in burns. Rapidly emerging nosocomial pathogens and the problem of multi-drug resistance necessitates periodic review of isolation patterns and antibiogram in the burn ward. Aim:Keeping this in mind, the present retrospective study from wounds of patients admitted to burns unit was undertaken to determine the bacteriological profile and the resistance pattern from the burn ward over a period of three years (June 2002 to May 2005) and was compared with the results obtained during the previous five years (June 1997-May 2002), to ascertain any change in the bacteriological profile and antimicrobial resistance pattern. Materials and Methods:Bacterial isolates from 268 wound swabs taken from burn patients were identified by conventional biochemical methods and antimicrobial susceptibility was performed. Statistical comparison of bacterial isolates and their resistance pattern with previous five years data was done using c2 test.Results and Conclusions:During the period from 2002 to 2005 Pseudomonas species was the commonest pathogen isolated (51.5%) followed by Acinetobacter species (14.28%), Staph. aureus (11.15%), Klebsiella species (9.23%) and Proteus species (2.3%). When compared with the results of the previous five years i.e., 1997 to 2002, Pseudomonas species was still the commonest pathogen in the burns unit. However, the isolation of this organism and other gram-negative organisms had decreased in comparison to previous years. Newer drugs were found to be effective.

scholarly journals ESBL producing Gram Negative Aerobic Bacteria Isolated from Burn Wound Infection with Their Antibiogram in Dhaka

2014 ◽  
Vol 10 (2) ◽  
pp. 63-69 ◽  
Author(s):  
MS Islam ◽  
M Abdullah Yusuf ◽  
M Shah Jahirul Hoque Chowdhury ◽  
M Afzal Hossain
Keyword(s):  
Wound Infection ◽  
Multi Drug Resistance ◽  
Periodic Review ◽  
Burn Wound ◽  
Esbl Producer ◽  
College Hospital ◽  
Klebsiella Species ◽  
E Coli ◽  
Medical College ◽  
Sensitivity Pattern

Background: Infection is an important cause of mortality in burns. Rapidly emerging nosocomial pathogens and the problem of multi-drug resistance necessitates periodic review of isolation patterns and antibiogram in the burn ward. Objective: The purpose of the present study was to see the frequency of bacteria in burn wound with their antibiotic sensitivity pattern. Method: This cross sectional study was conducted in the laboratory of Department of Microbiology at Dhaka Medical College, Dhaka and samples were collected from the burn unit of Dhaka Medical College Hospital, Dhaka. Bacterial isolates from 108 wound swabs taken from burn patients were identified by conventional biochemical methods and antimicrobial susceptibility was performed. Result: Out of 98 bacteria E. coli (20.4%) was most common and 25.0% of these bacteria were ESBL producer. Out of 14 Klebsiella species ESBL producer was in 6(42.9%). ESBL producing Proteus species (21.4%) and Pseudomonas species (14.9%) were also detected. Klebsiella (33.91%) was the predominant organism closely followed by Pseudomonas (31.84%). Conclusion: E. coli is the most common ESBL producing bacteria causing the burn wound infection. DOI: http://dx.doi.org/10.3329/jsf.v10i2.17959 J Sci Found, 2012;10(2):63-69

scholarly journals Antibiotic Susceptibility Pattern of Bacteria Isolated from an Urban Referral Hospital in Dhaka City

2016 ◽  
Vol 2 (2) ◽  
pp. 7-11
Author(s):  
M Mushfequr Rahman ◽  
J Ashraful Haq ◽  
MAH Golam Morshed ◽  
Farida Huq
Keyword(s):  
Antibiotic Susceptibility ◽  
Referral Hospital ◽  
Dhaka City ◽  
Bacterial Strains ◽  
Klebsiella Species ◽  
Acinetobacter Species ◽  
Pseudomonas Species ◽  
Judicious Choice ◽  
Almost All ◽  
First And Second Generation

The present study was to assess the pattern of antibiotic susceptibility of the isolated bacteria in an urban referral hospital in Dhaka City. A total of 393 bacterial strains were isolated from various specimens over a l0-months period. The majority of the organisms were Escherichia coli Q3.33oh) followed by Klebsiella species (27.480 ), Staphylococcas aureus (l7.Oioh),Lcinetobacter species (8.l4yo), Pseudomonas species (7.l2Yo), and others. The thirdgeneration Cephalosporins Hke Ceftriaxone, Ceftazidime and Cefotaxime were sensitive against 45-66yo isolated Enterobacteriaceae. The first- and second-generation Cephalosporins were less effective. The sensitivity to Ciprofloxacin of various Enterobacteriaceae was only between 33-4Oo compared to 52.8-67.9Vo against Gentamicin. Majority of the Enterobacteriaceae were resistant to Ampicillin, whereas almost all of the Enterobacteriaceae (94-100%o) were sensitive to Imipenem. Ahont97.UY;s Acinetobacter species were susceptible to Imipenem. Sensitivity of the organism (Acinetobacter) to third-generation Cephalosporins ranged between 50-560 , whereas 40.60/o were found sensitive to Ciprofloxacin. The sensitivity to Chloramphenicol, Co-trimoxazole, Cephalexin and Ampicillin ranged between 9.3oh to 34.30 . About 93.0%o of Pseudomonas species were sensitive to Imipenem. The rate of susceptibility to Gentamicin and Netilmicin was higher than those of the Ciprofloxacin and Ceftriaxone (67.80/o and, 53.57o vs, 39.2yo), About 707o of isolated S. aureus were resistant to OxacilHn but all were sensitive to Vancomycin. The result of this study would help the physicians to make a judicious choice of,.anti.biotics for therapeutic purposes.Bangladesh J Med Microbiol 2008; O2 (02):7-ll

scholarly journals Bacterial Isolates and Their Antibiograms of Burn Wound Infections in Burns Specialist Hospital in Baghdad

2013 ◽  
Vol 10 (2) ◽  
pp. 331-340 ◽  
Author(s):  
Baghdad Science Journal
Keyword(s):  
Generation Cephalosporin ◽  
Multi Drug Resistance ◽  
Resistant Bacteria ◽  
Bacterial Isolates ◽  
Burn Wound ◽  
Hospital Policy ◽  
Acinetobacter Baumanii ◽  
Fifth Generation ◽  
Drug Resistant Bacteria ◽  
Providencia Stuartii

A total of 54 out of 67 (80.59%) of burn wound swab showed growth of one, or two, or three bacterial pathogens. Pseudomonas aeruginosa was the commonest pathogen, isolated in 48.14% of swab samples, followed by Klebsiella pneumoniae (31.48%), Staphylococcus aureus (27.77%), Acinetobacter baumanii (14.81%), Escherichia coli (7.40%), and Citrobacter freundii, Providencia stuartii, Enterobacter cloacae, with 1.85% isolation percentage for each. All bacterial isolates were tested against 19 antibiotics, and showed multi-drug resistance to 10 antibiotics, or more. The most effective antibiotics were the fifth-generation cephalosporin, ceftobiprole, and and antibiotic combinations, as Ceftazidime / clavulanic acid, and Cefoperazone /sulbactam, and newer generation fluoroquinolone, levofloxacin, and gemifloxacin, which are attractive candidates to be the basic antibiotics in establishment of new hospital policy in Iraq for treatment of burn wound infection of multi-drug resistant bacteria

Resistance Pattern of Extended Spectrum β-Lactamase Producing Gram-Negative Pathogens from Surgical Site Infections

2019 ◽  
Vol 12 (6) ◽  
pp. 4709-4712
Author(s):  
G. S. Sharanathe ◽  
S. A Gadgil
Keyword(s):  
Surgical Site Infections ◽  
Resistance Pattern ◽  
Klebsiella Species ◽  
Gram Negative ◽  
E Coli ◽  
Diffusion Technique ◽  
Pseudomonas Species ◽  
Esbl Producers ◽  
Standard Disk ◽  
Operative Wound

There is an increasing resistance for drugs in first line of treatment for post-operative wound. It has imposed the practitioners the use of newer antibiotics. β-lactamase production is the most important mechanism of resistance to the penicillin and cephalosporins. The present study was undertaken with the objective of isolation of ESBL producing gram-negative pathogens from surgical site infections and to study their resistance pattern. A total number of 28 surgical hospitals were selected for the collection of post operative wound infection samples. The ESBL producing pathogens were detected by phenotypic screening and confirmatory methods as recommended by CLSI guidelines 2012. A standard disk diffusion technique for antimicrobial susceptibility testing was performed as recommended by clinical and laboratory standard institute (CLSI). The total number of ESBL producers was 141 (37.80 %) while the number of non-ESBL producers was 232 (62.20 %). The distribution of ESBL producing E. coli, Klebsiella species, Proteus species and Pseudomonas species was 74 (55.64%), 42 (6.20%), was 16 (22.22 %) and 09 (17.31 %) respectively. The ESBL producing isolates were highly resistant to Cephalosporin, Ampicillin, Ciprofloxacin, Gentamycin and Cotromoxazole while they were highly susceptible to Ceftazidime/Cluvanic acid, Piperacillin / Tazobactam, Imipenem and Meropenum. In conclusion, the present study shows the considerable occurrence of ESBL producers among the Gram-negative isolates from surgical site infections and their increasing multidrug resistance.

scholarly journals Antimicrobial activity of Ankaferd Blood Stopper® against nosocomial bacterial pathogens

Open Medicine ◽  
2010 ◽  
Vol 5 (2) ◽  
pp. 198-202 ◽  
Author(s):  
Zeynep Saribas ◽  
Burcin Sener ◽  
Ibrahim Haznedaroglu ◽  
Gulsen Hascelik ◽  
Serafettin Kirazli ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Enterococcus Species ◽  
Klebsiella Species ◽  
Acinetobacter Species ◽  
Pseudomonas Species ◽  
Ankaferd Blood Stopper ◽  
Hemostatic Disorders ◽  
Clinical Conditions

AbstractThe aim of this study is to investigate the in vitro antimicrobial activity of Ankaferd Blood Stopper® against methicillin-resistant Staphylococcus aureus (MRSA), Enterococcus species, Escherichia coli, Pseudomonas species, Acinetobacter species and Klebsiella species of nosocomial origin. Ankaferd inhibited growth in 72.4% to 100% of the bacteria tested, depending on the type of the isolate. As a result, it can be stated that Ankaferd inhibits the in vitro growth of nosocomial bacteria. This is a novel, important finding since severe hospital infections coexist with many hemostatic disorders, and the use of Ankaferd may increase hemostatic potential in such clinical conditions.

scholarly journals Bacteriology of the burn wound at the Bai Jerbai Wadia Hospital for children, Mumbai, India-A 13-year study, Part I-Bacteriological profile

2009 ◽  
Vol 42 (02) ◽  
pp. 213-218
Author(s):  
Shankar Srinivasan ◽  
Arvind M. Vartak ◽  
Aakanksha Patil ◽  
Jovita Saldanha
Keyword(s):  
Antibiotic Sensitivity ◽  
Age Group ◽  
Treatment Facility ◽  
Burn Wound ◽  
Bacteriological Profile ◽  
Sensitivity Pattern ◽  
Burn Unit ◽  
Set Up ◽  
Burns Unit ◽  
Microbiological Data

ABSTRACT Aim: To study which organisms were prevalent in our burn unit and their antibiotic sensitivity pattern in brief. Method: Microbiological data of 1534 patients admitted to the burns unit of the Bai Jerbai Wadia Hospital for Children, Mumbai over a period of 13 years (1994-2006) was reviewed retrospectively. A total of 9333 swabs were cultured and antibiotic sensitivities to the isolated organisms determined. The age group of patients admitted to our facility ranged from one month to 15 years. Result: Klebsiella was the predominant organism in our set-up (33.91%), closely followed by Pseudomonas (31.84%). The antibiotic sensitivities of the isolated organisms are discussed in detail in the text. Conclusion: Every treatment facility has microorganisms unique to it and these change with time. It is therefore of paramount importance to have an in-depth knowledge of the resident organisms and their antibiotic sensitivity pattern so that infection-related morbidity and mortality are improved.

scholarly journals Aerobic Bacterial Isolates and Their Antibiotic Susceptibility Patterns of Pus Samples at Tertiary Healthcare Center of Northern India

2021 ◽  
Vol 8 (9) ◽  
pp. 247-251
Author(s):  
Aditya Rana ◽  
Veehteeanveshna Gupta ◽  
Subhash Chand Jaryal
Keyword(s):  
Staphylococcus Aureus ◽  
Antibiotic Resistance ◽  
Antibiotic Susceptibility ◽  
Diffusion Method ◽  
Resistance Pattern ◽  
Bacterial Isolates ◽  
Northern India ◽  
Gram Staining ◽  
Bacteriological Profile ◽  
Tertiary Healthcare

Introduction: Emerging resistance in microorganisms is a matter of great concern in health care setups. Bacterial isolate and AMR pattern changes from place to place and time to time. Unprofessional use of antibiotics has resulted in an increasing burden of antibiotic resistance. This study focused over the aerobic bacteriological profile and antibiotic resistance pattern in pus isolates. Materials and Methods: A retrospective study was carried out from June, 2020 to May 2021. 1174 pus samples collected during the study period were included. The samples were cultured on Blood and MacConkey agar. After aerobic incubation at 37°C for 18-24 hrs, organisms were identified by biochemical reactions, gram staining and antibiotic susceptibility was tested by Kirby Bauer disc diffusion method. Result: Among the total 1174 pus samples, 712 (60.6%) were male and 462 (39.3%) were females. 857(72.9%) samples showed positive results. Among them, Staphylococcus aureus was the most common isolate followed by Escherichia coli, Pseudomonas spp. and Klebsiella spp. The sensitivity of Staphylococcus aureus was highest with Vancomycin and Linezolid, whereas Enterobacterales and Pseudomonas were sensitive with Piperacillin tazobactam. Conclusion: Increasing resistance always poses a challenge in treating infections. The development of resistant strains of pathogens can be limited by the judicious use of antibiotics. This study shows the infecting bacterial isolates and their antibiogram from this area. Keywords: Pus, antimicrobial resistance, bacterial isolates.

scholarly journals Bacterial profile and multi-drug resistance pattern of bacterial isolates among septicemia suspected cases: a meta-analysis report in Ethiopia

2021 ◽  
Vol 45 (3) ◽  
pp. 167-178
Author(s):  
Mengistu Abayneh ◽  
Shewangizaw HaileMariam ◽  
Molla Asnake
Keyword(s):  
Drug Resistance ◽  
Blood Culture ◽  
Meta Analysis ◽  
Multi Drug Resistance ◽  
Resistance Pattern ◽  
Bacterial Isolates ◽  
Gram Positive ◽  
Gram Negative ◽  
Drug Resistance Pattern ◽  
Culture Positive

Abstract Background Bloodstream infections (BSIs) are one of the most common infections seen in all age groups and in all locations. The current knowledge on the patterns of bacterial profile, and its antibiotic resistance are essential to design and implement appropriate interventions. This study was conducted to assess the prevalence and multi-drug resistance pattern of bacterial isolates among septicemia and/or bacteremia suspected cases in Ethiopia. Methods Searching was conducted in databases of PubMed, Research Gate, Scopus and Google Scholar. In addition, manual searching is also conducted in bibliographies of included studies and in other meta-analysis studies. Required data were extracted from articles published up to 2020 on the bacterial profile of septicemia in Ethiopia, and analyzed using comprehensive meta-analysis version 3.3.0 software. Results A total of 5,823 septicemia suspected cases were extracted from 18 included studies and the overall blood culture positive rate of 31.9% (95% CI: 0.261–0.382). Of these, the overall Gram positive and Gram negative isolates was 57.8% (95% CI: 0.534–0.584) and 42.2% (95% CI: 0.416–0.466), respectively. Among Gram positives, predominantly reported isolates was Staphylococcus  aureus (47.9%: 480 of 1,003), followed by Coagulase-Negative Staphylococcus (42.7%: 428 of 1,003), whereas among Gram negatives, the most frequently reported isolates was Klebsiella species (29.8%: 218 of 731), followed by Escherichia  coli (23.1%: 169 of 731). Significant levels of resistance was reported against ampicillin, amoxicillin, ceftriaxone, co-trimoxazole and tetracycline with a pooled resistance range of 40.6–55.3% in Gram positive and 52.8–85.7% in Gram negative isolates. The pooled estimates of multi-drugs resistance (MDR) was (66.8%) among Gram positives and (80.5%) among Gram negatives, with the overall MDR rate of (74.2%). Conclusions The reported blood culture positive rates among septicemia cases were relatively high. Second, the level of drug and multi-drug resistant isolates against commonly prescribed antibiotics was significant. However, the scarcity of data on culture confirmed septicemia cases as well as patterns of antimicrobial resistance may overshadow the problem.

scholarly journals Distribution of Bacterial Strains and their Antibiotic Sensityvity Profile in an Urban Referral Hospital

2018 ◽  
Vol 25 ◽  
pp. 72-76
Author(s):  
M Bulbul Hasan ◽  
S Gul Nahar ◽  
M Nawshad Ali ◽  
Mst Rokeya Khatun ◽  
Chinmoy Kanti Das
Keyword(s):  
Referral Hospital ◽  
Third Generation ◽  
Bacterial Strains ◽  
Klebsiella Species ◽  
Acinetobacter Species ◽  
The Third ◽  
Pseudomonas Species ◽  
Judicious Choice ◽  
Almost All ◽  
Third Generation Cephalosporins

Then Present study was done to assess the distribution of bacterial pathogens with their pattern of antibiotic susceptibility in an urban referral hospital in RMCH. A total of 393 bacteria strains were isolated from various specimens over a 10-months period. The majority of the organisms were Escherichia coli (33.33%) followed by Klebsiella species (27.48%), staphylococcus aureus (17.05%), Acinetobcter species (8.14%), Pseudomonas species (7.12%), and others. The third-generation Cephalosporins like Ceftriaxone, Ceftazidime and Cefotaxime were sensitive to Ciprofloxacin of various Enterobacteriaceae was only between 33-40% compared to 52.8-37.9% against Gentamicin. Majority of the Enterobacteriaceae were resistant to Ampicillin, whereas almost all of the Enterobacteriaceae (94-100%) were sensitive to Imipenem. About 97.0% Acinetobacter species were susceptible to Imipenem. Sensitivity of the organism (Acinetobacter) to third-generation Cephalosporins ranged between 50-56%, whereas 40.6% were found sensitive to Ciprofloxacin. The sensitivity to Chloramphenicol, Co-trimixazole, Cephalexin and Ampicillin ranged between 9.3% to 34.3%. About 93.0% of Pseudomonas species were sensitive to Imipenem. The rate of susceptibility to Gentamicin and Netilmicin was higher than those of the Ciprofloxacin and Ceftriaxone (37.8% and 53.5% vc. 39.2%). About 70% of isolated S. aureus were resistane of Oxacillin but all were sensitive to Vancomycin. The result of this study would help the physicians to make a judicious choice of antibiotics for therapeutic purposes.TAJ 2012; 25: 72-76

scholarly journals Incidence and Antibiogram of Acinetobacter Causing Neonatal Sepsis Among Hospitalised Patients

2020 ◽  
Vol 19 (1) ◽  
pp. 20-23
Author(s):  
Syeda Shahnoor Hasina Mamtaz ◽  
Abu Hena Md Saiful Karim Chowdhury ◽  
Gulshan Ara Begum ◽  
Asma Ferdousi ◽  
Mohammad Shahab Uddin
Keyword(s):  
Neonatal Sepsis ◽  
Antibiotic Sensitivity ◽  
Testing Time ◽  
Sensitivity Testing ◽  
Klebsiella Species ◽  
Acinetobacter Species ◽  
Bacteriological Profile ◽  
Hospitalised Patients ◽  
Sensitivity Pattern ◽  
Acinetobacter Spp

Background: Acinetobacter species are typical nosocomial pathogens causinginfections and high mortality, almost exclusively in compromised hospitalizedpatients. Multidrug-resistant Acinetobacter spp. blood infection in the neonatalintensive care unit patients create a great problem in hospital settings. The studywas done to detect prevalence of acinetobacter spp. as the causative agent ofneonatal sepsis with its antibiogram Materials and methods: A total of 100 clinically suspected neonatal sepsis caseswas enrolled in the study. Bacteriological profile and antibiotic sensitivity pattern ofacinetobacter spp. were done accordingly. Results: Among the 100 suspected neonatal sepsis cases, 28% were culture positiveand 72% were culture negative. Klebsiella species was the predominant isolatedbacteria which was 53.58% followed by Acinetobacter spp. (14.28%) E. coli(10.72%)Pseudomonas spp. (7.14%) S. aureus (7.14%) & Candida (7.14%). Acinetobacter spp.showed 100% resistant to ampicillin, ciprofloxacin, gentamycin, amikacin,ceftazidime, cefotaxime & cefepime, 75% resistant to meropenem & 50% sensitiveto levofloxacin. Conclusion: It is essential to conduct periodic bacteriological profile along withroutine antimicrobial sensitivity testing time to time for effective management ofneonatal sepsis. Chatt Maa Shi Hosp Med Coll J; Vol.19 (1); January 2020; Page 20-23

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