scholarly journals Temperature and Humidity of Expired Air of Sheep

1988 ◽  
Vol 41 (3) ◽  
pp. 309 ◽  
Author(s):  
KG Johnson ◽  
SM Callahan ◽  
R Strack
Keyword(s):  
Air Temperature ◽  
Upper Respiratory Tract ◽  
Deep Body Temperature ◽  
Thermally Induced ◽  
Air Temperatures ◽  
Temperature And Humidity ◽  
Before And After ◽  
Upper Respiratory ◽  
Deep Body ◽  
Expired Air

The temperature and humidity of expired air from three adult Merino sheep were measured at air temperatures of 20, 30 and 40�C before and after the animals were shorn. Expired air was apparently always saturated with water vapour. At the higher air temperatures the temperature of expired air was close to deep body temperature; at lower air temperatures, expired air had been significantly cooled, e.g. to 32� 3�C in shorn sheep at 20�C air temperature. Expired air was cooler from shorn than from unshorn animals at 20 and 30�C air temperature, possibly due to thermally induced vasomotor changes in the upper respiratory tract. Cooling of expired air would be expected to lead to recovery of some of the water evaporated during inspiration; at 20�C air temperature, this fraction was estimated to be 25% in unshorn sheep and 36% in shorn sheep.

scholarly journals Inappropriate Azithromycin Use in Nine Primary-Care Clinics Before and After Implementation of Provider Guidance in the EMR

2020 ◽  
Vol 41 (S1) ◽  
pp. s292-s293
Author(s):  
Alexandria May ◽  
Allison Hester ◽  
Kristi Quairoli ◽  
Sheetal Kandiah
Keyword(s):  
Primary Care ◽  
Retrospective Chart Review ◽  
Antibiotic Prescribing ◽  
Upper Respiratory Tract ◽  
National Guidelines ◽  
Targeted Interventions ◽  
Primary Care Clinics ◽  
Before And After ◽  
Upper Respiratory ◽  
Tract Infections

Background: According to the CDC Core Elements of Outpatient Stewardship, the first step in optimizing outpatient antibiotic use the identification of high-priority conditions in which antibiotics are commonly used inappropriately. Azithromycin is a broad-spectrum antimicrobial commonly used inappropriately in clinical practice for nonspecific upper respiratory infections (URIs). In 2017, a medication use evaluation at Grady Health System (GHS) revealed that 81.4% of outpatient azithromycin prescriptions were inappropriate. In an attempt to optimize outpatient azithromycin prescribing at GHS, a tool was designed to direct the prescriber toward evidence-based therapy; it was implemented in the electronic medical record (EMR) in January 2019. Objective: We evaluated the effect of this tool on the rate of inappropriate azithromycin prescribing, with the goal of identifying where interventions to improve prescribing are most needed and to measure progress. Methods: This retrospective chart review of adult patients prescribed oral azithromycin was conducted in 9 primary care clinics at GHS between February 1, 2019, and April 30, 2019, to compare data with that already collected over a 6-month period in 2017 before implementation of the antibiotic prescribing guidance tool. The primary outcome of this study was the change in the rate of inappropriate azithromycin prescribing before and after guidance tool implementation. Appropriateness was based on GHS internal guidelines and national guidelines. Inappropriate prescriptions were classified as inappropriate indication, unnecessary prescription, excessive or insufficient treatment duration, and/or incorrect drug. Results: Of the 560 azithromycin prescriptions identified during the study period, 263 prescriptions were included in the analysis. Overall, 181 (68.8%) of azithromycin prescriptions were considered inappropriate, representing a 12.4% reduction in the primary composite outcome of inappropriate azithromycin prescriptions. Bronchitis and unspecified upper respiratory tract infections (URI) were the most common indications where azithromycin was considered inappropriate. Attending physicians prescribed more inappropriate azithromycin prescriptions (78.1%) than resident physicians (37.0%) or midlevel providers (37.0%). Also, 76% of azithromycin prescriptions from nonacademic clinics were considered inappropriate, compared with 46% from academic clinics. Conclusions: Implementation of a provider guidance tool in the EMR lead to a reduction in the percentage of inappropriate outpatient azithromycin prescriptions. Future targeted interventions and stewardship initiatives are needed to achieve the stewardship program’s goal of reducing inappropriate outpatient azithromycin prescriptions by 20% by 1 year after implementation.Funding: NoneDisclosures: None

EFFECT OF THE THERMAL ENVIRONMENT ON COLD RESISTANCE AND GROWTH OF SMALL INFANTS AFTER THE FIRST WEEK OF LIFE

PEDIATRICS ◽  
1968 ◽  
Vol 41 (6) ◽  
pp. 1033-1046 ◽  
Author(s):  
Leonard Glass ◽  
William A. Silverman ◽  
John C. Sinclair
Keyword(s):  
Cold Resistance ◽  
Thermal State ◽  
Thermal Environment ◽  
Test Environment ◽  
Deep Body Temperature ◽  
Abdominal Skin ◽  
Thermal Environments ◽  
Rate Of Increase ◽  
Before And After ◽  
Deep Body

Twelve matched pairs of small (1,001-2,000 gm birth weight) asymptomatic neonates, age 1 week, were placed in either of two frequently recommended thermal environments ("standard": abdominal skin controlled at 35.0°C to approximate the thermal state commonly realized in nurseries for premature infants; "warm": abdominal skin controlled at 36.5°C to approximate thermoneutral condition). Both groups were fed 120 calories/kg/day. Before and after 2 weeks in the test environment, the infants were placed in a simulated room environment-28°C incubator wall—for 1 hour and the change in body temperatures was measured. Cold resistance–the ability to prevent a fall of deep body temperature in the 28°C environment– was significantly greater among infants who had spent 2 weeks in the slightly cooler environment. The rate of increase in body weight and length was significantly faster in the warmer condition.

Infection Rates Before and After Diagnosis of IgA Vasculitis in Childhood: A Population-wide Study Using Non-exposed Matched Controls

2019 ◽  
Vol 47 (3) ◽  
pp. 424-430 ◽  
Author(s):  
Johannes C. Nossent ◽  
Warren Raymond ◽  
Helen Keen ◽  
David B. Preen ◽  
Charles A. Inderjeeth
Keyword(s):  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Upper Respiratory Tract Infections ◽  
Iga Vasculitis ◽  
Upper Respiratory Tract ◽  
Serious Infection ◽  
Serious Infections ◽  
Before And After ◽  
Upper Respiratory ◽  
Tract Infections

Objective.Clinical data suggest that infections can trigger IgA vasculitis (IgAV), but longterm observations are lacking. We compared rates, types, and microorganisms for serious infection before and after diagnosis for children with IgAV and non-exposed controls.Methods.Using population-based administrative linked health datasets we estimated incidence rates (IR) for serious infection per 1000 person-months for patients with IgAV (n = 504, age 5 yrs, 59.1% males) and controls matched for age, sex, and year of presentation (n = 1281, age 6 yrs, 66% males). Time zero (T0) was the date of IgAV diagnosis or equivalent date in controls, lookback (median 38 mos) was the period prior to T0, and followup (median 239 mos) was the period after T0.Results.During lookback, prevalence of serious infection was similar in patients with IgAV and controls (11.5% vs 9.5%, respectively), but patients with IgAV had a higher rate of upper respiratory tract infections [incidence rate ratio (IRR) 1.79; 95% CI 1.39–2.31] with shorter time between first serious infection and T0 (27 vs 43 mos; p = 0.02). During followup, patients were at a constant increased risk for serious infections (IRR 1.46, 95% CI 1.35–1.58). These rates were higher during followup: sepsis (IRR 12.6), pneumonia (IRR 6.19), upper respiratory tract infections (IRR 2.36), and skin infections (IRR 1.85). There was little overlap between patients with serious infections in the lookback and followup periods.Conclusion.In patients with childhood IgAV there is an increased longterm risk for a broader spectrum of infections, which is unrelated to serious infections prior to diagnosis or treatment. This suggests disease-specific factors may have a lasting effect on immune competence in childhood IgAV.

Glutamine and the effects of exhaustive exercise upon the immune response

1998 ◽  
Vol 76 (5) ◽  
pp. 524-532 ◽  
Author(s):  
Linda M Castell ◽  
Eric A Newsholme
Keyword(s):  
Immune Response ◽  
Respiratory Tract Infections ◽  
Opportunistic Infections ◽  
Exhaustive Exercise ◽  
Upper Respiratory Tract ◽  
High Incidence ◽  
Before And After ◽  
Prolonged Training ◽  
Upper Respiratory ◽  
Tract Infections

There is a high incidence of infections in athletes undergoing intense, prolonged training or participating in endurance races (e.g., the marathon), in particular, upper respiratory tract infections. Prolonged, exhaustive exercise can lower the plasma level of the amino acid, glutamine, which is an important fuel for some cells of the immune system and may have specific immunostimulatory effects. This could therefore be an important factor in the event of an impaired response of immune cells to opportunistic infections. The effects of feeding glutamine to sedentary individuals and to marathon and ultramarathon runners before and after prolonged, exhaustive exercise has been investigated in a series of studies that monitored the incidence of infections and some acute-phase response markers. Oral glutamine, compared with a placebo, appeared to have a beneficial effect on the incidence of infections reported by runners after a marathon.Key words: glutamine, endurance exercise, infections, immune response.

INFLUENCE OF TEMPERATURE AND HUMIDITY ON THE EMERGENCE BEHAVIOUR OF ANAX JUNIUS (ODONATA: AESHNIDAE)

1973 ◽  
Vol 105 (7) ◽  
pp. 975-984 ◽  
Author(s):  
Robert Trottier
Keyword(s):  
Relative Humidity ◽  
Water Temperature ◽  
Air Temperature ◽  
Water Surface ◽  
Average Speed ◽  
Anax Junius ◽  
Air Temperatures ◽  
Stage 4 ◽  
Temperature And Humidity ◽  
Three Stages

AbstractEmergence from the water of Anax junius Drury normally occurred after sunset. The onset was affected independently by water temperature and air temperature; low water temperature and high air temperature delayed the onset of emergence. In the field, the net vrtical distance travelled above the water, before ecdysis, was positively correlated with air temperature. In the laboratory, the vertical distance travelled above the water was greatest when air and water temperatures were approximately the same. The average speed of climbing to the first resting position above the water surface was faster at high than low water temperature, but the average speed of climbing from there to the final position, where ecdysis occurred, was reduced due to the effects of air temperature and humidity. Air temperatures below 12.6 °C were found to retard ecdysis and larvae returned to the water and emerged early the following day making the final process of emergence and ecdysis diurnal instead of nocturnal. The duration of ecdysis was shorter at high than low air temperatures and only the first three stages, as arbitrarily defined, were longer at low than high relative humidity; stage 4, shortened with low relative humidity. This study shows that A. Junius, emerging from the water is affected at first by the temperature experienced when submerged, but it becomes gradually and cumulatively affected by air temperature and humidity while climbing to the ecdysial position and moulting.

THE INFLUENCE OF ENVIRONMENTAL TEMPERATURE AND HUMIDITY ON SHOCK PRODUCED BY A CLAMPING PROCEDURE

1959 ◽  
Vol 37 (2) ◽  
pp. 165-174
Author(s):  
R. E. Haist ◽  
Rebeka Moscarello ◽  
T. L. Friedlich ◽  
J. R. Hamilton
Keyword(s):  
Air Temperature ◽  
Significant Influence ◽  
Environmental Temperature ◽  
Limb Ischemia ◽  
Optimum Temperature ◽  
Standard Temperature ◽  
Air Temperatures ◽  
Temperature And Humidity ◽  
Different Temperatures ◽  
Environmental Temperatures

The influence of environmental temperature on the development of shock produced by a clamping technique in rats was studied. In experiments in which the animals were subjected to different environmental temperatures during the period of limb ischemia, the best survival was obtained with an air temperature of 15 °C. At 9.5 °C and 40 °C the rats did not survive the 10-hour clamping period. When the clamping was carried out at a standard temperature (27 °C) and the rats were then transferred to a room at different temperatures just prior to clamp release, the best survival was obtained at or near a temperature of 24 °C. The temperature in the colon of the shocked rats fell quickly in a cooler environment and rose in a warmer one. When chlorpromazine (0.35 mg/100 g rat) was given at the time of clamp removal to rats kept thereafter at 9.4 °C, 20–21 °C, 24 °C, and 30 °C, survival was significantly prolonged at air temperatures of 20–21 °C, but not at 9.4 °C, 24 °C, or 30 °C. Changes in humidity had no significant influence on survival. The experiments show that the optimum temperature during the period of ischemia is different from that for hindering the development of shock following a period of ischemia.

THE INFLUENCE OF ENVIRONMENTAL TEMPERATURE AND HUMIDITY ON SHOCK PRODUCED BY A CLAMPING PROCEDURE

1959 ◽  
Vol 37 (1) ◽  
pp. 165-174
Author(s):  
R. E. Haist ◽  
Rebeka Moscarello ◽  
T. L. Friedlich ◽  
J. R. Hamilton
Keyword(s):  
Air Temperature ◽  
Significant Influence ◽  
Environmental Temperature ◽  
Limb Ischemia ◽  
Optimum Temperature ◽  
Standard Temperature ◽  
Air Temperatures ◽  
Temperature And Humidity ◽  
Different Temperatures ◽  
Environmental Temperatures

The influence of environmental temperature on the development of shock produced by a clamping technique in rats was studied. In experiments in which the animals were subjected to different environmental temperatures during the period of limb ischemia, the best survival was obtained with an air temperature of 15 °C. At 9.5 °C and 40 °C the rats did not survive the 10-hour clamping period. When the clamping was carried out at a standard temperature (27 °C) and the rats were then transferred to a room at different temperatures just prior to clamp release, the best survival was obtained at or near a temperature of 24 °C. The temperature in the colon of the shocked rats fell quickly in a cooler environment and rose in a warmer one. When chlorpromazine (0.35 mg/100 g rat) was given at the time of clamp removal to rats kept thereafter at 9.4 °C, 20–21 °C, 24 °C, and 30 °C, survival was significantly prolonged at air temperatures of 20–21 °C, but not at 9.4 °C, 24 °C, or 30 °C. Changes in humidity had no significant influence on survival. The experiments show that the optimum temperature during the period of ischemia is different from that for hindering the development of shock following a period of ischemia.

The effect of milk given at various temperatures on the oxygen consumption of young calves

1971 ◽  
Vol 13 (4) ◽  
pp. 619-625 ◽  
Author(s):  
C. W. Holmes
Keyword(s):  
Oxygen Consumption ◽  
Energy Balance ◽  
Air Temperature ◽  
Rectal Temperature ◽  
Heat Production ◽  
Young Female ◽  
Cool Liquid ◽  
Air Temperatures ◽  
Before And After

SUMMARY1. Measurements of oxygen consumption and rectal temperature were made on young female calves at air temperatures of 9° and 20°C, before and after 4·5 kg milk was drunk at 23° and 39°C.2. When cool milk (23°C) was drunk at an air temperature of 9°C, vigorous shivering occurred, and during the 2-hr period after feeding, oxygen consumption was significantly higher than in the three other treatments.3. In all other treatments oxygen consumption increased considerably during the 30-min period which included drinking activity; the average increment, when no thermo-regulatory shivering occurred, was 1·9 ml O2 min−1kg−1.4. It was estimated that the 58 kcal ‘heat of warming’ required by milk at 23°C drunk at an air temperature of 9°C could be accounted for by the increment in heat production during the 2 hr after feeding and the fall in rectal temperature of 0-2-0-3°C which persisted after feeding in this treatment. These calculations suggested that the effect of a cool liquid on the energy balance of an animal would be less than that predicted from the ‘heat of warming’ required by the cool liquid.

Thermoregulatory control of expired air temperature in diving harp seals

1989 ◽  
Vol 257 (2) ◽  
pp. R306-R310 ◽  
Author(s):  
L. P. Folkow ◽  
A. S. Blix
Keyword(s):  
Heat Exchange ◽  
Critical Temperature ◽  
Metabolic Rate ◽  
Water Temperature ◽  
Air Temperature ◽  
Dive Duration ◽  
Phoca Groenlandica ◽  
Lower Critical Temperature ◽  
Before And After ◽  
Expired Air

Expired air temperature (Tex), metabolic rate (MR), and skin (Ts) and body (Tb; rectal) temperatures were recorded in four or five young (1-2 yr) harp seals (Phoca groenlandica) in air [mean air temperature (Ta) = -30, -10, or 10 degrees C] and in water [mean water temperature (Tw) = 2.3 or 24.8 degrees C, with Ta = -30, -10, 0, or 10 degrees C]. Apparent lower critical temperature was below -10 degrees C in air. Above this Ta, mean MR was 5.85 W.kg-0.75 (2.23 W.kg-1), while mean MR was 12.56 W.kg-0.75 (4.69 W.kg-1) at Ta -30 degrees C. When seals were immersed in water of 2.3 degrees C, mean MR was 6.13 W.kg-0.75 (2.31 W.kg-1), regardless of Ta.At Ta -30, -10, and 10 degrees C, mean Tex in air were 9.5, 13.0, and 25.0 degrees C, respectively. The corresponding values for seals in water (Tw = 2.3 degrees C) were 8.0, 9.5, and 15.5 degrees C, respectively. The low Tex recorded at Ta -30 and -10 degrees C in air and at all Ta in water (Tw = 2.3 degrees C) suggests that heat was conserved by nasal heat exchange. At Ta 10 degrees C, mean Tex of seals in air was approximately 10 degrees C higher than mean Tex of seals in water (Tw = 2.3 degrees C). Furthermore, seals subjected to a Tw of 24.8 degrees C at Ta 0 degrees C had a mean Tex 10 degrees C higher than when subjected to Tw 2.3 degrees C at the same Ta. These observations suggest that Tex in seals is under thermoregulatory control. In a series of forced dives of up to 5-min duration Tex was found to be the same before and after the dive regardless of dive duration and Ta.

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