Australia’s rangelands: a future vision

2012 ◽  
Vol 34 (1) ◽  
pp. 33 ◽  
Author(s):  
Guy Fitzhardinge
Keyword(s):  
Systems Thinking ◽  
Ecological Systems ◽  
Agricultural Products ◽  
Historical Trends ◽  
The Real ◽  
Community Attitudes ◽  
Future Vision ◽  
Ecologically Sustainable ◽  
Range Of Values

The rangelands of Australia and their communities can be represented as a diverse and interrelated complex of social and ecological systems. For the development of a sustainable future for both social and ecological systems, thinking needs to be at a level that accommodates the interaction of all systems and not just part of them. Historical trends show that continued emphasis on increased production in agriculture does little to improve the real wealth of the industry in the long term. Changing community attitudes in relation to the value of the rangelands present both threats and opportunities for the inhabitants of the rangelands. It is argued that capitalising on the wider range of values represented by the landscape beyond only production of generic agricultural products and mining presents a more viable path to an ecologically sustainable and socially acceptable future for the Australian rangelands.

Hidden “holes” in the capital of banks and the supply of credit to the real sector of economy

2018 ◽  
pp. 49-68 ◽  
Author(s):  
M. E. Mamonov
Keyword(s):  
Credit Risk ◽  
The Other ◽  
Real Sector ◽  
Capital Management ◽  
Loan Loss ◽  
Short Term ◽  
The Real ◽  
Ex Post ◽  
The One

Our analysis documents that the existence of hidden “holes” in the capital of not yet failed banks - while creating intertemporal pressure on the actual level of capital - leads to changing of maturity of loans supplied rather than to contracting of their volume. Long-term loans decrease, whereas short-term loans rise - and, what is most remarkably, by approximately the same amounts. Standardly, the higher the maturity of loans the higher the credit risk and, thus, the more loan loss reserves (LLP) banks are forced to create, increasing the pressure on capital. Banks that already hide “holes” in the capital, but have not yet faced with license withdrawal, must possess strong incentives to shorten the maturity of supplied loans. On the one hand, it raises the turnovers of LLP and facilitates the flexibility of capital management; on the other hand, it allows increasing the speed of shifting of attracted deposits to loans to related parties in domestic or foreign jurisdictions. This enlarges the potential size of ex post revealed “hole” in the capital and, therefore, allows us to assume that not every loan might be viewed as a good for the economy: excessive short-term and insufficient long-term loans can produce the source for future losses.

Predictors of long-term cryoglobulinemic vasculitis outcomes after HCV eradication with direct-acting antivirals in the real-life

2021 ◽  
pp. 102923
Author(s):  
Laura Gragnani ◽  
Serena Lorini ◽  
Silvia Marri ◽  
Caterina Vacchi ◽  
Francesco Madia ◽  
...  
Keyword(s):  
Real Life ◽  
Cryoglobulinemic Vasculitis ◽  
Direct Acting Antivirals ◽  
The Real ◽  
Direct Acting

scholarly journals Einsatz von Secukinumab bei Patienten mit Psoriasis und Psoriasis-Arthritis – Ergebnisse einer nichtinterventionellen Studie unter Praxisbedingungen (SERENA-Studie)

2021 ◽  
pp. 1-3
Author(s):  
Michael Sticherling
Keyword(s):  
Observational Study ◽  
Real World ◽  
Human Monoclonal Antibody ◽  
Rapid Onset ◽  
Onset Of Action ◽  
The Real ◽  
Interleukin 17A ◽  
Favourable Safety ◽  
Favourable Safety Profile

<b>Introduction:</b> Secukinumab, a fully human monoclonal antibody that directly inhibits interleukin-17A, has demonstrated robust efficacy in the treatment of moderate to severe psoriasis (PsO), psoriatic arthritis (PsA) and ankylosing spondylitis (AS), with a rapid onset of action, sustained long-term clinical responses and a consistently favourable safety profile across phase 3 trials. Here, we report the clinical data at enrolment from SERENA, designed to investigate the real-world use of secukinumab across all three indications. <b>Methods:</b> SERENA is an ongoing, longitudinal, observational study conducted at 438 sites across Europe in patients with moderate to severe plaque PsO, active PsA or active AS. Patients should have received at least 16 weeks of secukinumab treatment before enrolment in the study. <b>Results:</b> Overall 2800 patients were included in the safety set; patients with PsA (N = 541) were older than patients with PsO (N = 1799) and patients with AS (N =  460); patients with PsO had a higher mean body weight than patients with PsA and patients with AS; and patients with PsO and patients with AS were predominantly male. Time since diagnosis was longer in patients with PsO compared with patients with PsA and patients with AS, and about 40% of patients were either current or former smokers. The proportion of obese patients (body mass index ≥ 30 kg/m<sup>2</sup>) was similar across indications. Patients were treated with secukinumab for a mean duration of 1 year prior to enrolment (range 0.89–1.04). The percentages of patients with prior biologics exposure were 31.5% PsO, 59.7% PsA and 55% AS. The percentages of patients prescribed secukinumab monotherapy were 75% (n =  1349) in PsO, 48.2% (n = 261) in PsA and 48.9% (n = 225) in AS groups. <b>Conclusion:</b> Baseline demographics of the study population are consistent with existing literature. This large observational study across all secukinumab indications will provide valuable information on the long-term effectiveness and safety of secukinumab in the real-world setting.

scholarly journals CANDIDE et la monnaie

2009 ◽  
Vol 52 (1) ◽  
pp. 75-103
Author(s):  
Jean-Pierre Aubry ◽  
Pierre Duguay
Keyword(s):  
Interest Rate ◽  
Interest Rates ◽  
Term Structure ◽  
Structural Equations ◽  
Reduced Form ◽  
Real Sector ◽  
Short Term ◽  
The Real ◽  
Structure Equations

Abstract In this paper we deal with the financial sector of CANDIDE 1.1. We are concerned with the determination of the short-term interest rate, the term structure equations, and the channels through which monetary policy influences the real sector. The short-term rate is determined by a straightforward application of Keynesian liquidity preference theory. A serious problem arises from the directly estimated reduced form equation, which implies that the demand for high powered money, but not the demand for actual deposits, is a stable function of income and interest rates. The structural equations imply the opposite. In the term structure equations, allowance is made for the smaller variance of the long-term rates, but insufficient explanation is given for their sharper upward trend. This leads to an overstatement of the significance of the U.S. long-term rate that must perform the explanatory role. Moreover a strong structural hierarchy, by which the long Canada rate wags the industrial rate, is imposed without prior testing. In CANDIDE two channels of monetary influence are recognized: the costs of capital and the availability of credit. They affect the business fixed investment and housing sectors. The potential of the personal consumption sector is not recognized, the wealth and real balance effects are bypassed, the credit availability proxy is incorrect, the interest rate used in the real sector is nominal rather than real, and the specification of the housing sector is dubious.

scholarly journals Alemtuzumab in the long-term treatment of relapsing-remitting multiple sclerosis: an update on the clinical trial evidence and data from the real world

2017 ◽  
Vol 10 (10) ◽  
pp. 343-359 ◽  
Author(s):  
Tjalf Ziemssen ◽  
Katja Thomas
Keyword(s):  
Multiple Sclerosis ◽  
Adverse Events ◽  
Mechanism Of Action ◽  
Real World ◽  
Continuous Treatment ◽  
The Real ◽  
Relapsing Remitting ◽  
Remitting Multiple Sclerosis ◽  
Relapsing Remitting Multiple Sclerosis

Alemtuzumab is a humanized monoclonal antibody approved for the treatment of relapsing-remitting multiple sclerosis (RRMS), given as two annual courses on five consecutive days at baseline and on three consecutive days 12 months later. Here we provide an update on the long-term efficacy and safety of alemtuzumab in RRMS, including real-world experience, and advances in our understanding of its mechanism of action. Recent data from the phase II/III extension study have demonstrated that alemtuzumab reduces relapse rates, disability worsening, and the rate of brain volume loss over the long term, with many patients achieving no evidence of disease activity. In high proportions of patients, preexisting disability remained stable or improved. Alemtuzumab is associated with a consistent safety profile over the long term, with no new safety signals emerging and the overall annual incidence of reported adverse events decreasing after the first year on treatment. Acyclovir prophylaxis reduces herpetic infections, and monitoring has been shown to mitigate the risk of autoimmune adverse events, allowing early detection and overall effective management. Data from clinical practice and ongoing observational studies are providing additional information on the real-world use of alemtuzumab. Recent evidence on the mechanism of action of alemtuzumab indicates that in addition to its previously known effects of inducing depletion and repopulation of T and B lymphocytes, it also results in a relative increase of cells with memory and regulatory phenotypes and a decrease in cells with a proinflammatory signature, and may further promote an immunoregulatory environment through an impact on other innate immune cells (e.g. dendritic cells) that play a role in MS. These effects may allow preservation of innate immunity and immunosurveillance. Together, these lines of evidence help explain the durable clinical efficacy of alemtuzumab, in the absence of continuous treatment, in patients with RRMS.

scholarly journals Análisis del tostado del grano de café

2019 ◽  
pp. 1-16
Author(s):  
Adolfo RAMÍREZ-ROMÁN ◽  
Ángel SUÁREZ-ÁLVAREZ ◽  
Jacqueline CHABAT-URANGA ◽  
Francisco ORTIZ-MARTÍNEZ
Keyword(s):  
Quality Management ◽  
Case Studies ◽  
Continuous Improvement ◽  
Educational Program ◽  
Agricultural Products ◽  
Environmental Care ◽  
Roasting Process ◽  
Statistical Results ◽  
Ground Powder

Analyzing coffee grain roasting operations - Veracruz Region will contribute to the distribution of equipment and machinery in the Industrial Engineering workshop of the Educational Program. It aims to obtain improvements in the roasting process through the study of the work (January–June 2019), to lay the foundation for the proposals of Systems of Quality Management, Safety and Environmental Care in the following phases of the project (2019-2020) with effects on continuous improvement. In the coffee industry in Mexico has in the medium and long term, opportunities to grow and consolidate. As with most agricultural products from smallholders, such as coffee, the prices paid for the input ("cherry coffee") They are far from what the processed coffee comes to obtain in presentations of soluble and ground powder for coffee makers, and the process of improvement, quality, efficiency in roasting activities is necessary. The method analyzed the case studies of the operations of companies, producers and research related to the coffee and coffee industry and the interpretation of the statistical results.

scholarly journals State and prospects of competition, communications and logistics of agro-food products

2021 ◽  
Vol 262 ◽  
pp. 03017
Author(s):  
Hadis Rakhaev ◽  
Anzor Gyatov ◽  
Zalina Ivanova ◽  
Elvira Kokova ◽  
Akhmat Chochaev
Keyword(s):  
Communication Systems ◽  
Raw Materials ◽  
Agricultural Products ◽  
Real Situation ◽  
The Real ◽  
Logistics Networks ◽  
Chemical Products ◽  
The Government ◽  
Set Up ◽  
New Criteria

Communication and logistics are one of the most important features of the markets; they permeate and constitute its content. Communication and logistics for commodity producers are also as important attribute as production itself, and sometimes even more. For this reason, commodity producers themselves directly and explicitly, but more often through other institutions (including the government), tend to set up stable exclusive communication systems and logistics. This article analyzes the state of the prospects for the formation of communications and logistics networks for agricultural products. The correlation of existing communications and logistics of agricultural products and other types of products (including finished industrial products of various purposes: from machinery, equipment, chemical products to defense, hydrocarbon, carbon and other raw materials, timber and other goods) is analyzed. The established linkages are revealed. They were quantified, calibrated and classified. The existing principles (comparative and absolute advantages) are reviewed and new principles are formulated (marginal player, marginal linkages), which describe the real situation in the markets of agricultural products more correctly. New criteria for grouping and reformatting existing communication and logistics networks, which make it possible to increase the competitiveness of domestic agricultural products are proposed.

scholarly journals Conditions for increasing the export of agricultural products in our country in the context of a pandemic

2021 ◽  
Vol 2 (2/S) ◽  
pp. 172-178
Author(s):  
Hojiakbar Fayzullaev ◽  
Umidjon Dadabaev
Keyword(s):  
Agricultural Sector ◽  
Agricultural Products ◽  
High Quality ◽  
Vegetables And Fruits ◽  
Dignified Life

This article examines the sectors of the economy of countries during the pandemic, as well as the issues of growing and exporting agricultural products. The article examines the processes of production of vegetables and fruits in the agricultural sector, their processing high - quality supply of the population, and export. In this article, the authors emphasize the importance of reforms and measures taken in our country not only to save the economy in the event of a pandemic but also to protect our greatest wealth from threats, to ensure their dignified life and long-term development.

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