Analysis of females with Chlamydia trachomatis infections attending a sexually transmissible infection clinic in Singapore in 2010

Sexual Health ◽  
2013 ◽  
Vol 10 (5) ◽  
pp. 470
Author(s):  
Lynette C. M. Low ◽  
Feng Ling G. Tan ◽  
Ellen Chan ◽  
Martin Chio ◽  
Roy Chan ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Sexual Partners ◽  
Diagnostic Methods ◽  
Chlamydia Infection ◽  
Skilled Workers ◽  
Population Demographics ◽  
Sexual Histories ◽  
Rising Incidence ◽  
Sexually Transmissible Infection ◽  
Transmissible Infection

Background Chlamydia (Chlamydia trachomatis) is the most commonly diagnosed sexually transmissible infection (STI) in Singapore, with rising incidence. Method: Random sampling was performed on all chlamydia-positive samples collected from female patients who attended a women’s clinic from January 2010 to December 2010. Some 250 electronic medical records were analysed. Population demographics, sexual histories, symptoms, diagnostic methods and management were recorded. Results: One hundred and forty-two (56.8%) patients were under 25 years of age. The predominant race diagnosed with Chlamydia cervicitis were Chinese (116 cases, 46.4%) followed by 86 (34.4%) Malays and 20 (8%) Filipinos. Sixty-three (25.2%) were skilled workers and (47) 18.8% were students. Professionals and office workers together formed 68 (27.2%) of the patients. Some 248 (99.2%) patients were heterosexual and 2 (0.8%) patients were bisexual; 229 (91.6%) patients had regular partners, 18 (7.2%) had casual partners and 3 (1.2%) had both. Concurrency prevalence accounted for 49 cases (19.6%) and condom use was less common. Patients were generally asymptomatic, with 114 (45.5%) presenting with symptoms. One hundred and eight (43.2%) patients had 2–5 sexual partners in their lifetime. Patients with a termination made up 12% of our cohort. This episode of infection was the first diagnosis of an STI for 198 (79.2%) patients; 24 (9.6%) of patients had been previously diagnosed with chlamydia. Conclusion: Chlamydia infection was most prevalent in skilled workers and their regular partners with heterosexual practices under 25 years old. Most patients had 2–5 sexual partners and did not use condoms consistently or at all.

Unsupervised screening for chlamydia and gonorrhoea in backpacker hostels in Manly, Sydney

Sexual Health ◽  
2013 ◽  
Vol 10 (2) ◽  
pp. 185 ◽  
Author(s):  
Stephen C. Davies ◽  
Brooke Shepherd ◽  
Rebecca Wiig ◽  
Iain Kaan
Keyword(s):  
Chlamydia Trachomatis ◽  
Neisseria Gonorrhoeae ◽  
Sexual Partner ◽  
Pilot Project ◽  
Sexual Partners ◽  
Priority Group ◽  
A Priority ◽  
Sexually Transmissible Infection ◽  
Transmissible Infection

Young international backpackers frequently have new sexual partners. We conducted a pilot project of unsupervised screening for chlamydia (Chlamydia trachomatis) and gonorrhoea (Neisseria gonorrhoeae) by self-collected specimens at two backpacker hostels in Manly, Sydney. The median age was 24 years for men and 23 years for women. A new sexual partner during travel was reported by 94%, of whom only 20% always using condoms. The prevalence of chlamydia was 11.9% (14.3% of 35 men and 10.2% of 49 women). No cases of gonorrhoea were detected. Half of the dispensed testing kits went missing or were tampered with, and there was spoilage of the receptacle bins, which persisted despite a redesign to a more secure and locked box. While populations such as young backpackers may be a priority group for sexually transmissible infection screening, we advise caution for projects contemplating an unsupervised model.

Men's attitudes towards chlamydia screening: a narrative review

Sexual Health ◽  
2012 ◽  
Vol 9 (2) ◽  
pp. 120 ◽  
Author(s):  
Myles Balfe ◽  
Ruairi Brugha ◽  
Emer O'Connell ◽  
Deirdre Vaughan ◽  
Diarmuid O'Donovan
Keyword(s):  
General Practice ◽  
Chlamydia Trachomatis ◽  
Narrative Review ◽  
Future Research ◽  
Chlamydia Screening ◽  
Perceived Vulnerability ◽  
Screening Services ◽  
Urine Testing ◽  
Sexually Transmissible Infection ◽  
Transmissible Infection

Objectives Chlamydia trachomatis is a sexually transmissible infection (STI) that affects significant numbers of men. Research on men’s perspectives on chlamydia screening (or testing) has been limited. We conducted a narrative review to examine: (1) what factors encourage or discourage men from attending health services for chlamydia screening, and/or from accepting screening once it has been offered to them, and (2) where men want chlamydia screening services to be located. Methods: A narrative review of the recent peer-reviewed literature (published between 1999 and 2009) on men’s attitudes towards chlamydia screening. To be included, articles had to explore men’s perspectives on screening (which could be ascertained through quantitative or qualitative studies, or from relevant discussion papers or reviews). Results: Forty-eight articles were included in all. Men’s attitudes towards chlamydia screening are influenced by their knowledge about the infection, their perceived vulnerability to the infection, the degree of embarrassment and shame that they associate with screening and the stigma that they associate with screening. Men prefer to be offered urine testing for chlamydia. Men want to be offered screening by non-judgemental professionals. Men’s attitudes towards screening for chlamydia in general practice, genito-urinary medicine clinics, home and outreach settings are also explored in this review. Conclusions: Several factors influence men’s attitudes towards screening. Two central themes underlie and influence many of these factors: men’s needs to make positive impressions on others, and men’s identification with particular ideals of masculinity. The review concludes with suggestions for future research on this topic.

Association between sexually transmissible infection testing, numbers of partners and talking to partners and friends about sexual health: survey of young adults

Sexual Health ◽  
2017 ◽  
Vol 14 (4) ◽  
pp. 378 ◽  
Author(s):  
Natalie A. Hendry ◽  
Graham Brown ◽  
Gary W. Dowsett ◽  
Marina Carman
Keyword(s):  
At Risk ◽  
Young Adults ◽  
Sexual Health ◽  
Health Knowledge ◽  
Sexual Partners ◽  
Group Method ◽  
Friendship Networks ◽  
Sti Testing ◽  
Sexually Transmissible Infection ◽  
Transmissible Infection

Background Young adults, aged 18–30 years, comprise the largest proportion of sexually transmissible infection (STI) notifications in Australia compared with other age groups. Understanding the influence of partner and friendship networks on their STI testing practices may enhance health promotion efforts to increase testing for this group. Method: Participants aged 21–30 years, living in Australia for ≥3 years, were recruited within nightlife precincts in Melbourne, Australia. They completed a survey on demographic items, sexual health attitudes, sexual health knowledge and STI testing experiences and perceptions. Responses to items related to talking to partners and friends about STI testing were allocated partner and friend communication scores. Analyses included χ2 tests of independence and independent sample t-tests. Results: Overall, 36.5% (61/167) of participants had tested for STIs in the previous 12 months. Of those who had tested for STIs, most had significantly higher numbers of sexual partners in the same period (P < 0.05), and were significantly more likely to have felt at risk of STI acquisition (P < 0.05). Significantly greater mean partner and friend communication scores were associated with higher numbers of sexual partners, feeling at risk of STIs, and testing for STIs in the previous 12 months (all P < 0.05). There were no significant differences when participants were stratified by gender or age. Conclusion: Talking to partners and friends about STI testing is associated with testing rates for young adults. Feeling at risk and increased numbers of sexual partners may be associated with the promotion of STI testing among friends and partners.

Young women's misperceptions about sexually transmissible infection testing: a 'clean and clear' misunderstanding

Sexual Health ◽  
2007 ◽  
Vol 4 (4) ◽  
pp. 273 ◽  
Author(s):  
Sara K. Head ◽  
Richard A. Crosby ◽  
Lydia A. Shrier ◽  
Gregory R. Moore
Keyword(s):  
Young Women ◽  
Sexual Debut ◽  
Risk Behaviour ◽  
Healthcare Setting ◽  
Cross Sectional Study ◽  
Sexual Risk Behaviour ◽  
Cross Sectional ◽  
Sti Testing ◽  
Sexually Transmissible Infection ◽  
Transmissible Infection

Background: This exploratory study investigated young women’s perceptions of sexually transmissible infection (STI) testing received during gynaecological care. Correlates of the incorrect perception that STI testing occurred were assessed. Methods: Cross-sectional study of sexually active young women, age 18–24 years, attending a university healthcare setting for gynaecological care (n = 109). Two hundred and four women were approached and 87 were ineligible; of the remaining 117, 93.2% chose to enrol. Results: Of the women enrolled, 25.7% falsely perceived that they were STI tested (labelled ‘clean and clear’). Only approximately one in seven (14.7%) accurately understood the STI for which they were tested. In multivariate analyses, controlling for race, STI symptoms, depression, number of lifetime visits to the gynaecologist, and suspicion of current STI, three variables were significant: minority race (adjusted odds ratio (AOR) = 4.84, confidence interval (CI) = 1.38–16.96, P = 0.01), earlier age at sexual debut (AOR = 4.67, CI = 1.73–12.57, P = 0.002), and previous STI diagnosis (AOR = 3.38, CI = 1.07–10.66, P = 0.04). Comment: The findings suggest that many young women may have an inaccurate understanding of the STI testing they undergo during gynaecological care and may operate under the misperception they are ‘clean and clear’ of STI. Women with said misperception were more likely to be of minority race and report relatively earlier age of sexual debut and previous STI diagnosis. Further investigation is warranted to determine whether the ‘clean and clear’ misperception influences young women’s sexual risk behaviour.

Exploring the acceptability of online sexually transmissible infection testing for rural young people in Victoria

2014 ◽  
Vol 22 (1) ◽  
pp. 40-44 ◽  
Author(s):  
Jane E. Tomnay ◽  
Lisa Bourke ◽  
Christopher K. Fairley
Keyword(s):  
Young People ◽  
Sexually Transmissible Infection ◽  
Transmissible Infection

Addressing sexually transmissible infection in HIV-positive patients. A clinical audit

Sexual Health ◽  
2007 ◽  
Vol 4 (1) ◽  
pp. 75 ◽  
Author(s):  
Danielle Esler ◽  
Catriona Ooi
Keyword(s):  
New England ◽  
Clinical Audit ◽  
Sexual History ◽  
Hiv Positive ◽  
History Taking ◽  
Health Unit ◽  
Sti Testing ◽  
Sexual History Taking ◽  
Sexually Transmissible Infection ◽  
Transmissible Infection

Australian guidelines for sexual history taking and sexually transmissible infection (STI) screening of HIV-positive patients do not exist. An audit was conducted to assess current practices of sexual history taking and STI testing of HIV-positive patients attending Hunter New England Sexual Health Unit.

scholarly journals Australian sexually transmissible infection and HIV testing guidelines for asymptomatic men who have sex with men 2014: a review of the evidence

Sexual Health ◽  
2014 ◽  
Vol 11 (3) ◽  
pp. 217 ◽  
Author(s):  
David J. Templeton ◽  
Phillip Read ◽  
Rajesh Varma ◽  
Christopher Bourne
Keyword(s):  
Nucleic Acid Amplification ◽  
Effective Control ◽  
Sexually Active ◽  
Chlamydia Testing ◽  
Sexually Transmissible Infections ◽  
Sex With Men ◽  
Time Required ◽  
Sexually Transmissible Infection ◽  
Transmissible Infection ◽  
Asymptomatic Men

Men who have sex with men (MSM) in Australia and overseas are disproportionately affected by sexually transmissible infections (STIs), including HIV. Many STIs are asymptomatic, so regular testing and management of asymptomatic MSM remains an important component of effective control. We reviewed articles from January 2009–May 2013 to inform the 2014 update of the 2010 Australian testing guidelines for asymptomatic MSM. Key changes include: a recommendation for pharyngeal chlamydia (Chlamydia trachomatis) testing, use of nucleic acid amplification tests alone for gonorrhoea (Neisseria gonorrhoeae) testing (without gonococcal culture), more frequent (up to four times a year) gonorrhoea and chlamydia testing in sexually active HIV-positive MSM, time required since last void for chlamydia first-void urine collection specified at 20 min, urethral meatal swab as an alternative to first-void urine for urethral chlamydia testing, and the use of electronic reminders to increase STI and HIV retesting rates among MSM.

scholarly journals Chlamydia trachomatis detection in HIV infected patients using polymerase chain reaction

2013 ◽  
Vol 2 (1) ◽  
pp. 12-16
Author(s):  
A Shrestha ◽  
N Adhikari ◽  
Y Shah ◽  
P Poudel ◽  
B Acharya ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Chlamydia Trachomatis ◽  
Public Health Problem ◽  
Chlamydia Infection ◽  
Hiv Positive ◽  
Chain Reaction ◽  
Hiv Patients ◽  
Important Public Health Problem ◽  
Sexually Transmitted ◽  
Polymerase Chain

Introduction: Chlamydia trachomatis is a sexually transmitted organism and causes important public health problem in the sexually active age group. Limited studies are found regarding the prevalence of C. trachomatis in Nepal. Moreover, currently there are no any study in Nepal reporting the association of chlamydia and HIV infection. This study attempts to determine the burden of chlamydia on HIV positive patients. Materials and Methods: A total of 117 HIV positive patients visiting a HIV clinic in Kathmandu, were screened for chlamydia infection. For this, urine samples were collected and analyzed using the Polymerase Chain Reaction Technique (PCR). Results: C. trachomatis was detected in 4.2% of the total 117 HIV patients. Out of positive cases 60% were males and 40% were females. However, chlamydia was found more prevalent among females (6.8%) than males (3.4%). Eighty percent of positive cases were asymptomatic. Conclusions: Although, the prevalence of chlamydia infection was found less HIV patients, most of those cases were asymptomatic. Therefore, routine checkup is recommended for all suspected cases for timely management of the disease. DOI: http://doi.dx.org/10.3126/ijim.v2i1.8003 Int J Infect Microbiol 2013;2(1):12-16

scholarly journals Identification of differentially expressed circular RNAs in HeLa cells infected with Chlamydia trachomatis

2019 ◽  
Vol 77 (7) ◽  
Author(s):  
Yuanjun Liu ◽  
Chunmin Hu ◽  
Yina Sun ◽  
Haoqing Wu ◽  
Xiaojun Chen ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Signaling Pathways ◽  
Hela Cells ◽  
Expression Profiles ◽  
Quantitative Polymerase Chain Reaction ◽  
Host Cells ◽  
Differentially Expressed ◽  
Chlamydia Infection ◽  
Circular Rnas ◽  
Mrna Microarray

ABSTRACT Non-coding circular RNAs (circRNAs) have been shown to have important roles in many diseases; however, no study has indicated circRNAs are involved in Chlamydia trachomatis infection. In this study, we used circRNA microarray to measure the global circRNA expression profiles in HeLa cells with or without C. trachomatis serovar E (Ct.E) infection. CircRNA/miRNA/mRNA interactions were predicted and bioinformatics analyses were performed. The differentially expressed circRNAs were selected according to our criterion for validation by reverse-transcription and quantitative polymerase chain reaction (RT-qPCR). The mRNA microarray was used to detect the mRNA expression profiles after Ct.E infection. Among 853 differentially expressed circRNAs, 453 were upregulated and 400 were downregulated after Ct.E infection. Target miRNAs and miRNA-targeted mRNAs of these circRNAs were predicted. RT-qPCR analysis indicated hsa_circRNA_001226, hsa_circRNA_007046 and hsa_circRNA_400027 were elevated similar to those determined in the circRNA microarray analysis. The mRNA microarray results showed 915 genes were upregulated and 619 genes were downregulated after Ct.E infection. Thirty-four differentially expressed genes overlapped in the bioinformatics and mRNA microarray results. KEGG pathway analysis revealed several signaling pathways, including endocytosis, MAPK and PI3P-Akt signaling pathways, that were targeted by circRNAs may play important roles in Chlamydia infection. This study provides evidence that circRNAs in host cells are involved in the process of Chlamydia infection.

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