Analyzing Blood Pressure Ascent during Aging in Non-Diabetics: Focusing on Links to Insulin Resistance and Body Fat Mass

2021 ◽  
Vol 40 (4) ◽  
pp. 317-326
Author(s):  
Harry G. Preuss ◽  
Gilbert R Kaats ◽  
Nate Mrvichin ◽  
Debasis Bagchi
Keyword(s):  
Insulin Resistance ◽  
Blood Pressure ◽  
Body Fat ◽  
Fat Mass ◽  
Body Fat Mass

scholarly journals Dietary Isoliquiritigenin at a Low Dose Ameliorates Insulin Resistance and NAFLD in Diet-Induced Obesity in C57BL/6J Mice

2018 ◽  
Vol 19 (10) ◽  
pp. 3281 ◽  
Author(s):  
Youngmi Lee ◽  
Eun-Young Kwon ◽  
Myung-Sook Choi
Keyword(s):  
Insulin Resistance ◽  
Energy Expenditure ◽  
Body Fat ◽  
Fat Mass ◽  
High Fat Diet ◽  
Plasma Cholesterol ◽  
Cellular Respiration ◽  
Body Fat Mass ◽  
High Fat ◽  
Diet Induced Obesity

Isoliquiritigenin (ILG) is a flavonoid constituent of Glycyrrhizae plants. The current study investigated the effects of ILG on diet-induced obesity and metabolic diseases. C57BL/6J mice were fed a normal diet (AIN-76 purified diet), high-fat diet (40 kcal% fat), and high-fat diet +0.02% (w/w) ILG for 16 weeks. Supplementation of ILG resulted in decreased body fat mass and plasma cholesterol level. ILG ameliorated hepatic steatosis by suppressing the expression of hepatic lipogenesis genes and hepatic triglyceride and fatty acid contents, while enhancing β-oxidation in the liver. ILG improved insulin resistance by lowering plasma glucose and insulin levels. This was also demonstrated by the intraperitoneal glucose tolerance test (IPGTT). Additionally, ILG upregulated the expression of insulin signaling-related genes in the liver and muscle. Interestingly, ILG elevated energy expenditure by increasing the expression of thermogenesis genes, which is linked to stimulated mitochondrial biogenesis and uncoupled cellular respiration in brown adipose tissue. ILG also suppressed proinflammatory cytokine levels in the plasma. These results suggest that ILG supplemented at 0.02% in the diet can ameliorate body fat mass, plasma cholesterol, non-alcoholic fatty liver disease, and insulin resistance; these effects were partly mediated by increasing energy expenditure in high-fat fed mice.

scholarly journals Zat gizi, massa lemak tubuh, dan tekanan darah pada wanita vegetarian dan nonvegetarian berusia 20-30 tahun

2017 ◽  
Vol 6 (1) ◽  
pp. 17-28
Author(s):  
Stela Maris Adinda Budi Kirana ◽  
Etisa Adi Murbawani ◽  
Binar Panunggal
Keyword(s):  
Blood Pressure ◽  
Fatty Acids ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Diastolic Blood Pressure ◽  
Saturated Fatty Acid ◽  
Body Fat ◽  
Fat Mass ◽  
Monounsaturated Fatty Acids ◽  
Body Fat Mass

Background : Vegetarians tend to have a risk of underfat. Several studies have reported that vegetarians have lower fat and higher fiber intake, lower body fat mass and blood pressure than nonvegetarians. There are only few studies about those variabels in 20-30 year-old subject. Objective : To analyze the difference of nutrients intake, body fat mass, and blood pressure between 20-30-year-old vegetarian and nonvegetarian women.Methods : Cross-sectional study design in 26 vegetarian women and 26 nonvegetarian women who was selected by consecutive sampling. Nutrients intake were obtained by Semi Quantitative Food Frequency Questionaire (SQFFQ) and analyzed by Nutrisurvey. Body fat mass was measured using Bioelectrical Impedance Analysis (BIA). Blood pressure was measured using Mercury sphygmomanometer. Data were analyzed using Independent t-test and Mann-Whitney test.Result : There were 38.5% of  vegetarians and 3.8% of nonvegetarians classified as underfat. There were 30.7% of vegetarians and 50% of  nonvegetarians classified as prehypertension. There were difference in fat (p=0.005), saturated fatty acid (p=0.000), monounsaturated fatty acids (p=0.002), polyunsaturated fatty acids (p=0.043), fiber (p=0.000), potassium (p=0.000), magnesium (p=0.004); body fat mass (p=0.021); and sistolic blood pressure (p=0.004) between both of groups. There weren’t difference energy intake (p=0.098), carbohydrate (p=0.207), protein (p=0.535), sodium (p=0.784), calcium (p=0.798), and diastolic blood pressure (p=0.799) between both of groups.Conclusion : Between vegetarian group and nonvegetarian group, there were difference in fat, saturated fatty acid, monounsaturated fatty acids, polyunsaturated fatty acids, fiber, potassium, magnesium intake; body fat mass; and sistolic blood pressure. However, there weren’t diffference in energy, carbohydrate, protein, sodium, calcium intake, and diastolic blood pressure between vegetarian group and nonvegetarian group 

scholarly journals HUBUNGAN STATUS GIZI DAN TEKANAN DARAH DENGAN KADAR C-REACTIVE PROTEIN DARAH PADA SUBJEK DISLIPIDEMIA

2013 ◽  
Vol 8 (1) ◽  
pp. 17
Author(s):  
Mira Dewi ◽  
Rimbawan Rimbawan ◽  
Agustino Agustino
Keyword(s):  
Blood Pressure ◽  
Nutritional Status ◽  
Diastolic Blood Pressure ◽  
Body Fat ◽  
Fat Mass ◽  
Body Fat Mass ◽  
C Reactive Protein ◽  
Cross Sectional Survey ◽  
Reactive Protein ◽  
Waist Hip Ratio

The objective of this study was to analyze the association of nutritional status (Body Mass Index, waist circumference, waist-hip ratio, and body fat mass) and blood pressure with inflammation status which was assessed by blood C-reactive protein level in dyslipidemic subjects. The study design was cross sectional survey involving 81 dyslipidemic subjects in Bogor. The study showed that there were significant correlations between BMI, waist-hip ratio, body fat mass, and diastolic blood pressure with blood CRP level (p&lt;0.05). In conclusion, the higher percentage of over nutritional status, body fat mass, and diastolic blood pressure, the higher status of inflammation.<br />Keywords:

scholarly journals Body fat mass and the proportion of very large adipocytes in pregnant women are associated with gestational insulin resistance

2015 ◽  
Vol 40 (4) ◽  
pp. 646-653 ◽  
Author(s):  
H Svensson ◽  
L Wetterling ◽  
M Bosaeus ◽  
B Odén ◽  
A Odén ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Pregnant Women ◽  
Body Fat ◽  
Fat Mass ◽  
Body Fat Mass

scholarly journals Strong and Bitter Vegetables from Traditional Cultivars and Cropping Methods Improve the Health Status of Type 2 Diabetics: A Randomized Control Trial

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1813
Author(s):  
Anne Cathrine Thorup ◽  
Hanne Lakkenborg Kristensen ◽  
Ulla Kidmose ◽  
Max Norman Tandrup Lambert ◽  
Lars Porskjær Christensen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Fat ◽  
Fat Mass ◽  
Daily Intake ◽  
Area Under The Curve ◽  
Tolerance Test ◽  
Normal Diet ◽  
Oral Glucose ◽  
Body Fat Mass ◽  
Root Vegetables

Vegetables rich in bitter-tasting phytochemicals may exert enhanced beneficial effects against key factors associated with type two diabetes (T2D). This study investigates whether selected cultivars of bitter and strong-tasting (BST) Brassica and root vegetables exert greater health benefits on T2D patients compared to equivalent modern mild and sweet tasting (MST) vegetables. A 12-week randomized, controlled, parallel intervention study involved 92 T2D patients, who were allocated three different diets: (1) 500 g daily of bitter and strong-tasting (BST) vegetables; (2) 500 g daily of mild and sweet-tasting (MST) vegetables; (3) 120 g daily MST normal diet (control). Both vegetable diets contained root vegetables and cabbages selected based on sensory differences and content of phytochemicals. Prior to and after the study, all participants underwent an oral glucose tolerance test (OGTT), 24 h blood pressure measurements, DEXA scans, and fasted blood samples. Both diets high in vegetables significantly reduced the participants’ BMI, total body fat mass, and HbA1c levels compared to control, but in the BST group, significant differences were also found regarding incremental area under the curve glucose 240 min (OGTT) and fasting glucose levels. A high daily intake of root vegetables and cabbages showed significant health improvements in both vegetable groups. BST vegetables had the greatest impact on insulin sensitivity, body fat mass, and blood pressure compared to control; moreover, they further improved glycemic control compared to MST vegetables.

scholarly journals Overweight and blood pressure: results from the examination of a selected group of adolescents in northern Italy

2008 ◽  
Vol 11 (9) ◽  
pp. 905-913 ◽  
Author(s):  
G Turconi ◽  
L Maccarini ◽  
R Bazzano ◽  
C Roggi
Keyword(s):  
Blood Pressure ◽  
Body Fat ◽  
Fat Mass ◽  
Body Height ◽  
Cross Sectional Study ◽  
Northern Italy ◽  
Body Fat Mass ◽  
Cross Sectional ◽  
High Prevalence ◽  
Linear Correlation Analysis

AbstractObjectiveThe aim of the present study was to investigate blood pressure (BP) levels and their relationship with different indices of body fat in a group of adolescents, in order to evaluate the prevalence of hypertension and plan preventive and corrective strategies.DesignCross-sectional study in primary care.SettingAll high schools in the Aosta Valley region, northern Italy.SubjectsFive hundred and thirty-two adolescents of both sexes, aged 15·4 (standard deviation 0·7) years. The following parameters were measured: body weight, body height, body mass index (BMI), four skinfold thicknesses, body fat mass, waist and hip circumferences and BP.ResultsBMI data indicated a high prevalence of overweight subjects in both sexes, but higher in males, while the prevalence rate of obese adolescents was lower. Of the total, 11·8 % of subjects suffered from systolic hypertension, while 6·9 % suffered from diastolic hypertension. In linear correlation analysis, BMI and all adiposity indices, except waist:hip ratio, were found to be significantly associated (P ranging between 0·05 and 0·001) with both systolic BP and diastolic BP in both sexes, with r ranging between 0·152 and 0·359. Multiple regression analysis with the stepwise method showed BMI and body fat mass to have the strongest association (P < 0·001) with BP, with r ranging between 0·275 and 0·359.ConclusionUnless reversed, these conditions are worrying and predict the possible development of cardiovascular disease in adulthood. There is a pressing need to develop a comprehensive medical and nutrition plan, together with preventive and corrective strategies, in school programmes.

scholarly journals Serum Fibroblast Growth Factor 21 Levels Are Positively Associated with Metabolic Syndrome in Patients with Type 2 Diabetes

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Ruo-Yao Gao ◽  
Bang-Gee Hsu ◽  
Du-An Wu ◽  
Jia-Sian Hou ◽  
Ming-Chun Chen
Keyword(s):  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Body Fat ◽  
Fat Mass ◽  
Density Lipoprotein ◽  
Fibroblast Growth Factor 21 ◽  
Body Fat Mass ◽  
Fibroblast Growth

Background. Fibroblast growth factor 21 (FGF21) acts as a potent metabolic regulator. Serum FGF21 levels were significantly higher in obesity and type 2 diabetes mellitus (T2DM) populations. The aim of this study was to evaluate the relationship between serum FGF21 levels and metabolic syndrome (MetS) in T2DM patients. Methods. Fasting blood samples were obtained from 126 T2DM patients. MetS and its components were defined according to the diagnostic criteria from the International Diabetes Federation. Serum FGF21 concentrations were measured using a commercially available enzyme-linked immunosorbent assay. Results. Among these patients, 84 (66.7%) had MetS. Female gender, hypertension, systolic blood pressure (SBP), diastolic blood pressure (DBP), waist circumference (WC), body weight (BW), body mass index (BMI), body fat mass, fasting glucose, glycated hemoglobin level (HbA1c), triglyceride level (TG), urine albumin-to-creatinine ratio (UACR), insulin level, homeostasis model assessment of insulin resistance (HOMA-IR), and FGF21 levels were higher, whereas high-density lipoprotein cholesterol level (HDL-C) and estimated glomerular filtration rate (eGFR) were lower in DM patients with MetS. Univariate linear analysis revealed that hypertension, BMI, WC, body fat mass, SBP, DBP, logarithmically transformed TG (log-TG), low-density lipoprotein cholesterol (LDL-C) level, log-glucose, log-creatinine, log-UACR, log-insulin, and log-HOMA-IR positively correlated, whereas HDL-C and eGFR negatively correlated with serum FGF21 levels in T2DM patients. Multivariate forward stepwise linear regression analysis revealed that body fat mass (adjusted R2 change = 0.218; P=0.008) and log-TG (adjusted R2 change = 0.036; P<0.001) positively correlated, whereas eGFR (adjusted R2 change = 0.033; P=0.013) negatively correlated with serum FGF21 levels in T2DM patients. Conclusions. This study showed that higher serum FGF21 levels were positively associated with MetS in T2DM patients and significantly positively related to body fat mass and TG but negatively related to eGFR in these subjects.

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