scholarly journals Vitamin D insufficiency as a risk factor for reproductive losses in miscarriage

2021 ◽  
Vol 37 (sup1) ◽  
pp. 8-12
Author(s):  
V. E. Radzinsky ◽  
F. U. Ramazanova ◽  
M. B. Khamoshina ◽  
M. M. Azova ◽  
M. R. Orazov ◽  
...  
Keyword(s):  
Vitamin D ◽  
Risk Factor ◽  
Vitamin D Insufficiency ◽  
Reproductive Losses

Does vitamin D status predict weight gain or increase in waist circumference? Results from the longitudinal Health 2000/2011 Survey

2020 ◽  
Vol 23 (7) ◽  
pp. 1266-1272 ◽  
Author(s):  
Tuija Jääskeläinen ◽  
Satu Männistö ◽  
Tommi Härkänen ◽  
Katri Sääksjärvi ◽  
Seppo Koskinen ◽  
...  
Keyword(s):  
Vitamin D ◽  
Risk Factor ◽  
Weight Gain ◽  
Waist Circumference ◽  
Healthy Lifestyle ◽  
Adult Population ◽  
Population Based ◽  
Vitamin D Insufficiency ◽  
Vitamin D Status

AbstractObjective:To investigate whether vitamin D status predicts weight gain or increase in waist circumference during the 11-year follow-up in general adult population.Design:A population-based longitudinal study.Setting:The study was conducted using data from the nationally representative Health 2000/2011 Survey. The analyses were based on regression models adjusted for sociodemographic and lifestyle factors.Participants:Weight, waist circumference and vitamin D status (serum 25-hydroxyvitamin D concentration analysed with radioimmunoassay) were measured from 2924 participants aged 30–64 years at baseline.Results:In men, low vitamin D status at baseline predicted ≥10 % increase in waist circumference during the follow-up when adjusted for age only (OR for sufficient v. deficient S-25(OH)D 0·41; 95 % CI 0·25, 0·67; P for trend <0·01), but the association with weight gain was only borderline significant. After adjustment for potential confounders, low vitamin D status remained a significant predictor of increase in waist circumference, but the association with weight gain was further attenuated. In women, vitamin D status at baseline did not predict weight gain or increase in waist circumference.Conclusions:Our results suggest that vitamin D insufficiency may be a risk factor of abdominal obesity among men but not among women. In men, it may also increase the risk of weight gain. Further studies are required to confirm these findings and examine potential mechanisms behind them. There is also a possibility that vitamin D is a biomarker of healthy lifestyle rather than an independent risk factor for obesity.

Vitamin D insufficiency: A risk factor to vertebral fractures in community-dwelling elderly women

Maturitas ◽  
2009 ◽  
Vol 64 (4) ◽  
pp. 218-222 ◽  
Author(s):  
Jaqueline B. Lopes ◽  
Camille F. Danilevicius ◽  
Liliam Takayama ◽  
Valeria F. Caparbo ◽  
Márcia Scazufca ◽  
...  
Keyword(s):  
Vitamin D ◽  
Risk Factor ◽  
Vertebral Fractures ◽  
Elderly Women ◽  
Vitamin D Insufficiency ◽  
Community Dwelling

scholarly journals Is Vitamin D Insufficiency Associated with Mortality of Critically Ill Patients?

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Gulbin Aygencel ◽  
Melda Turkoglu ◽  
Ayse Fitnat Tuncel ◽  
Burcu Arslan Candır ◽  
Yelda Deligoz Bildacı ◽  
...  
Keyword(s):  
Vitamin D ◽  
Risk Factor ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Independent Risk Factor ◽  
Vitamin D Insufficiency ◽  
University Hospital ◽  
Median Serum ◽  
Vitamin D Levels ◽  
Sufficient Vitamin

Objective. To evaluate the vitamin D status of our critically ill patients and its relevance to mortality.Patients and Methods. We performed a prospective observational study in the medical intensive care unit of a university hospital between October 2009 and March 2011. Vitamin D levels were measured and insufficiency was defined as <20 ng/mL.Results. Two hundred and one patients were included in the study. The median age was 66 (56–77) and the majority of patients were male (56%). The median serum level of vitamin D was 14,9 ng/mL and 139 (69%) patients were vitamin D insufficient on admission. While we grouped the ICU patients as vitamin D insufficient and sufficient, vitamin D insufficient patients had more severe acute diseases and worse laboratory values on admission. These patients had more morbidities and were exposed to more invasive therapies during stay. The mortality rate was significantly higher in the vitamin D insufficient group compared to the vitamin D sufficient group (43% versus 26%,P=0,027). However, logistic regression analysis demonstrated that vitamin D insufficiency was not an independent risk factor for mortality.Conclusion. Vitamin D insufficiency is common in our critically ill patients (69%), but it is not an independent risk factor for mortality.

scholarly journals Vitamin D Deficiency as a Risk Factor for Schizophrenia: A meta-analysis of Observational Studies

2019 ◽  
Author(s):  
Jia-Lian Zhu ◽  
Wen-Wen Luo ◽  
Xuan Cheng ◽  
Yun Li ◽  
Qi-Zhi Zhang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
Risk Factor ◽  
Vitamin D Deficiency ◽  
Meta Analysis ◽  
Vitamin D Insufficiency ◽  
Cochrane Library ◽  
Vitamin D Levels ◽  
Schizophrenic Patients

Abstract Background: Schizophrenia is a heterogeneous disorder in which there is interaction between genetic and environmental factors. Study have found that vitamin D deficiency is a risk factor for schizophrenia. We conducted a meta-analysis to investigate the relationship between schizophrenia and blood vitamin D level.Methods: A systematic review and meta-analysis have been conducted. All published observational articles have been searched from PubMed, Web of Science, Scopus, Cochrane library and Embase until September 2019. The Newcastle-Ottawa scale was used to examine the quality of the included studies.Results: A total of 38 articles have been included in this study. The lower level of vitamin D was found in people with schizophrenia compared with controls (WMD =-4.50, 95%CI [-6.69, -2.32]). Subgroup analyses based on study design, the patient’s hospitalization status, quality of the study, outcomes, and the country explained part of between-study heterogeneity. No significant differences in publication bias were observed. The overall prevalence of vitamin D deficiency and insufficiency in schizophrenic patients were 66%, 95%CI [57%–76%] and 76%, 95%CI [69%, 83%], respectively. Subjects with schizophrenia were more likely to have vitamin D deficiency or vitamin D insufficiency compared to controls (2.03, 95%CI [1.49, 2.77]; 2.43, 95%CI [1.40, 4.23]).Conclusion: The results of this systematic review show that low vitamin D levels might contribute to the development of schizophrenia. The prevalence of vitamin D deficient or insufficient in schizophrenia was higher than that in healthy controls or another psychotic disease .

scholarly journals Vitamin D Insufficiency as Risk Factor of Severe Pneumonia in Children

2021 ◽  
Vol 9 (2) ◽  
pp. 058-056
Author(s):  
Christin Natalia Kalembang ◽  
Ayu Setyorini Mestika Mayangsari ◽  
Komang Ayu Witarini ◽  
Ni Putu Siadi Purniti ◽  
I Made Kardana ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Risk Factor ◽  
Odds Ratio ◽  
Adjusted Odds Ratio ◽  
Severe Pneumonia ◽  
Vitamin D Insufficiency ◽  
High Morbidity ◽  
Chi Square ◽  
Chi Square Test

Severe pneumonia is an infectious disease with high morbidity and mortality in children under five. Several risk factors of severe pneumonia have been established, one of them is vitamin D insufficiency. Risk factors for severe pneumonia can help clinicians to provide better quality of life. This research aimed to prove that vitamin D insufficiency is a risk factor for severe pneumonia in children. This analytical study with case-control design performed in children aged 2 months until 59 months old. Case consisted of 42 subjects who suffered severe pneumonia, while control consisted of 42 subjects who suffered pneumonia. Both groups fulfilled the eligibilities and matched proportionally based on age. The study was conducted from June 2019 to March 2021, level of 25(OH) D was checked in both groups. Data was analyzed by Chi-square test and logistic regression with significant level set at p<0, 05. Total eighty-four subjects with median age 11, 5 month were included in this study and most of them were male (59, 5%). The risk factors of severe pneumonia was vitamin D insufficiency with adjusted odds ratio 4.71 (CI95% 1.15-19.31, p=0.031) and exposure of cigarette smoke with adjusted odds ratio 5.19 (CI95% 1.76-15.31, p=0.003). There was no association of gender, mild malnutrition, non-exclusive breastfeeding and incomplete immunization in this study. Vitamin D insufficiency is a risk factor for severe pneumonia in children.

scholarly journals Examining chronic inflammatory markers on blood pressure measures in the presence of vitamin D insufficiency among indigenous cree adults: results from the cross-sectional Multi-Community Environment-and-Health Study in Eeyou Istchee, Quebec, Canada

BMJ Open ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. e043166
Author(s):  
Aleksandra M Zuk ◽  
Eric N Liberda ◽  
Leonard J S Tsuji
Keyword(s):  
Blood Pressure ◽  
Vitamin D ◽  
Risk Factor ◽  
Inflammatory Markers ◽  
Vitamin D Insufficiency ◽  
Health Study ◽  
Cross Sectional ◽  
Community Environment ◽  
Environment And Health ◽  
Tnf Α

ObjectiveHigh blood pressure (BP) is a risk factor for cardiovascular disease. Examining the role of inflammatory mediators on BP is important since vitamin D (VD) is a modifiable risk factor, which possibly modulates inflammatory cytokines. This study simulated what are known as average ‘controlled direct effects (CDE)’ of inflammatory markers, C reactive protein (CRP), tumour necrosis factor-α (TNF-α), and interlukin-6 (IL-6) on continuous BP measures, while fixing VD, an intermediate variable to specific level.DesignCross-sectional study.SettingWe analysed data from the Multi-Community Environment-and-Health Study, 2005–2009, conducted in Eeyou Istchee, Quebec, Canada.ParticipantsThis study recruited 1425 study Indigenous Cree participants from seven Cree communities. Only adults with serum VD levels, inflammatory markers and BP measures were included in this data analysis.Primary and secondary outcomes measuresInflammatory markers examined the top 25th exposure percentiles. VD ‘insufficiency’ (ie, 25-hydroxyvitamin-D levels<50 nmol/L) defined by the Institute of Medicine. CDE for each inflammatory marker in the presence and absence of population VD insufficiency simulated the average direct effect change for systolic and diastolic BP (SBP and DBP) measures. All models were adjusted for exposure-and-mediator outcome relationship.ResultsAmong 161 participants, 97 (60 %) were female. The prevalence of VD insufficiency was 32%. CDE estimates show in the presence and absence of population vitamin D insufficiency, inflammatory markers have a slightly different association on BP. TNF-α significantly and inversely associated with SBP in the presence of vitamin D insufficiency, fully adjusted model β = −13.61 (95% CI −24.42 to −2.80); however, TNF-α was not associated with SBP in the absence of vitamin D insufficiency. CRP, IL-6 were also not significantly associated with BP measures, although the magnitude of association was greater for those with elevated inflammation and VD insufficiency.ConclusionThis novel analysis shows in the presence of VD insufficiency, inflammation (particularly TNF-α) may affect SBP. Additional research is needed to elucidate these findings, and the temporal relationship between these variables.

Sign in / Sign up

Export Citation Format

Share Document