scholarly journals Vitamin D Insufficiency as Risk Factor of Severe Pneumonia in Children

2021 ◽  
Vol 9 (2) ◽  
pp. 058-056
Author(s):  
Christin Natalia Kalembang ◽  
Ayu Setyorini Mestika Mayangsari ◽  
Komang Ayu Witarini ◽  
Ni Putu Siadi Purniti ◽  
I Made Kardana ◽  
...  

Severe pneumonia is an infectious disease with high morbidity and mortality in children under five. Several risk factors of severe pneumonia have been established, one of them is vitamin D insufficiency. Risk factors for severe pneumonia can help clinicians to provide better quality of life. This research aimed to prove that vitamin D insufficiency is a risk factor for severe pneumonia in children. This analytical study with case-control design performed in children aged 2 months until 59 months old. Case consisted of 42 subjects who suffered severe pneumonia, while control consisted of 42 subjects who suffered pneumonia. Both groups fulfilled the eligibilities and matched proportionally based on age. The study was conducted from June 2019 to March 2021, level of 25(OH) D was checked in both groups. Data was analyzed by Chi-square test and logistic regression with significant level set at p<0, 05. Total eighty-four subjects with median age 11, 5 month were included in this study and most of them were male (59, 5%). The risk factors of severe pneumonia was vitamin D insufficiency with adjusted odds ratio 4.71 (CI95% 1.15-19.31, p=0.031) and exposure of cigarette smoke with adjusted odds ratio 5.19 (CI95% 1.76-15.31, p=0.003). There was no association of gender, mild malnutrition, non-exclusive breastfeeding and incomplete immunization in this study. Vitamin D insufficiency is a risk factor for severe pneumonia in children.

2018 ◽  
Vol 18 (1) ◽  
pp. 208
Author(s):  
Listautin Listautin

Diarrhea is one of health problem in the world including Indonesia. The Morbidity survey undertaken by Sub-Directorate of diarrhea, Health Department from 2007 to 2010is improved. According to the data gained from Puskesmas in Tanjung Pinang Jambi in 2017, it is found out that 5 different districs in Tanjung Pinang are the district which has the highest rate of diarrhea sufferers. The aim of this study is to find out the risk factors of the flies density and the dwelling sanitation to the occurance of diarrhea in Tanjung Pinang Jambi in 2017. This study is quantitative study by using case control design. The sample of this study is 68 people who consists of 34 samples of case group and 34 samples of control group. This study is analyzed through univariate and bivariate analysis by using chi-square test. The instruments of this study are the reviewed document, ceklist, and the measurement through fly grill. The result of analysis are found out that toilet is the main risk factor for the occurance of diarrhea with odds ratio (OR) value is 3,519. Sewerage (SPAL) is one the risk factor of the diarrhea occurance with odds ratio (OR) value is 3,361. The waste is the other risk factors for the occurance of diarrhea with odds ratio (OR) value is 4,418. The flies density is the protective factor for the diarrhea occurance with odds ratio (OR) value is 0,773.Based on the result of this study, it can be concluded that it is necesarry to do the coorporation across program to optimize the noticing of information to public concerning on the importance of good dwelling sanitation and the low flies density in order to avoid from the occurance of diarrhea.Keyword : Diarrhea, Dwelling Sanitation, Flies Density


2008 ◽  
Vol 19 (1) ◽  
pp. 34-39 ◽  
Author(s):  
Carlos Estrela ◽  
Cláudio Rodrigues Leles ◽  
Augusto César Braz Hollanda ◽  
Marcelo Sampaio Moura ◽  
Jesus Djalma Pécora

The aim of this study was to assess the prevalence and risk factors of apical periodontitis in endodontically treated teeth in a selected population of Brazilian adults. A total of 1,372 periapical radiographs of endodontically treated teeth were analyzed based on the quality of root filling, status of coronal restoration and presence of posts associated with apical periodontitis (AP). Data were analyzed statistically using odds ratio, confidence intervals and chi-square test. The prevalence of AP with adequate endodontic treatment was low (16.5%). This percentage dropped to 12.1% in cases with adequate root filling and adequate coronal restoration. Teeth with adequate endodontic treatment and poor coronal restoration had an AP prevalence of 27.9%. AP increased to 71.7% in teeth with poor endodontic treatment associated with poor coronal restoration. When poor endodontic treatment was combined with adequate coronal restoration, AP prevalence was 61.8%. The prevalence of AP was low when associated with high technical quality of root canal treatment. Poor coronal restoration increased the risk of AP even when endodontic treatment was adequate (OR=2.80; 95%CI=1.87-4.22). The presence of intracanal posts had no influence on AP prevalence.


2013 ◽  
Vol 131 (1) ◽  
pp. 27-34 ◽  
Author(s):  
Orlando Milhomem Mota ◽  
Maria Paula Curado ◽  
José Carlos Oliveira ◽  
Edesio Martins ◽  
Daniela Medeiros Milhomem Cardoso

CONTEXT AND OBJECTIVESEsophageal cancer is the eighth commonest type of cancer worldwide, occupying sixth place in terms of mortality. Smoking and alcohol use are known risk factors for this type of cancer. The aim here was to evaluate the risk factors for esophageal cancer in a low-incidence area.DESIGN AND SETTINGCase-control study in Goiânia, with 99 cases of esophageal cancer and 223 controls.METHODSThe variables were sociodemographic, dietary, occupational and lifestyle data. The sample was analyzed using the chi-square test, Mann-Whitney test and Mantel-Haenszel approach for multivariate analysis. Odds ratios (OR) were calculated with 5% significance and 95% confidence intervals.RESULTSThe risk of esophageal cancer was higher in patients ≥ 55 years (OR = 1.95; P < 0.001). Patients from rural areas were at greater risk of esophageal cancer (OR = 4.9; P < 0.001). Smoking was a risk factor among the cases (OR = 3.8; P < 0.001), as was exposure to woodstoves (OR = 4.42; P < 0.001). The practice of oral sex was not a risk factor (OR = 0.45; P = 0.04). Consumption of apples, pears, vegetables, cruciferous vegetables and fruit juices were protective against esophageal cancer.CONCLUSIONIn a region in which the incidence of esophageal cancer is low, the most significant risk factors were exposure to woodstoves, smoking and living in rural areas.


2016 ◽  
Vol 7 (01) ◽  
pp. 99-112
Author(s):  
Chairil

Diarrhea is one of the diseases that get priority eradication program because of the high morbidity and caused many deaths. In an effort to decrease the morbidity due to diarrhea important to know the factors that become menyebab incidence of the disease include the state of the environment, disease vector, personal hygiene, snack habits, and health services. The research was done at Village West Sidomulyo Tuah Karya and Sidomulyo subdistrict Puskesmas Handsome that during the period of the last 4-6 months of diarrhea always get into the top 10 diseases. The research objective was to determine the relationship between risk factors with the incidence of diarrhea. The study was a cross sectional study, using a questionnaire. Sampling was done by randomsampling, some 96 respondents. Results of research for the environmental health situation no association with diarrhea because of the test results chi-square statistic with continuity correction values obtained p = (1.00)> α = (0.05), disease-carrying vector no association with diarrhea because of test results chi-square statistic with continuity correction values obtained p = (1.00)> α = (0.05), there is no relationship between personal hygiene with diarrhea, because of the results of statistical chi-square test with continuity correction values obtained p = (0.69)> α = (0.05), there was no relationship between snacks at roadside with diarrhea, because of the results of statistical chi-square test with continuity correction values obtained p = (1.00)> α = (0, 05) there is no relationship between counseling with diarrhea, because of the results of statistical chi-square test with continuity correction values obtained p = (0.42)> α = (0.05), the variables being researched nothing to do with diarrhea , but it diskritif there, it is to note could be a risk for diarrhea will occur, it is necessary to promotive and preventive efforts. 


Author(s):  
Alviano Satria Wibawa ◽  
Hermina Novida ◽  
Muhammad Faizi ◽  
Deasy Ardiany

Introduction: Diabetic ketoacidosis (DKA) is a complication of diabetes mellitus which has a high risk of mortality. Mortality in DKA patients in developed countries is less than 5%, some other sources mention 5-10%, 2-10%, or 9-10%. Mortality events at clinics with simple facilities and elderly patients can reach 25-50%. The mortality rate of DKA patients is generally higher in infection conditions, especially in developing countries and in septic patients. Several factors such as age, sex, and high blood glucose can increase mortality risk of DKA patients. Other risk factors such as history of discontinued insulin therapy, impaired bicarbonate levels, pH, and increased leukocytes of DKA patients due to infection, abnormal albumin levels, electrolyte disturbances, and Serum Creatinine (SK) were thought to affect mortality of DKA patients. The purpose of this study was to determine the risk factors associated with mortality of DKA patients in Dr. Soetomo General Hospital Surabaya. Methods: The method used in this study was observational analytic involving 63 adult patients diagnosed with DKA with analysis using Chi-Square test. Results: From 63 patients included in this study, 37 patients diagnosed with DKA died and 26 patients lived. In a multivariate analysis, DKA severity with p = 0.001 (p < 0.005) was identified as having a relationship with mortality of DKA patients Dr. Soetomo General Hospital Surabaya. Conclusion: Severity is the only risk factor associated with mortality of DKA patients in Dr. Soetomo General Hospital Surabaya.


2015 ◽  
Vol 4 (4) ◽  
Author(s):  
Riska Agustina ◽  
Bambang Budi Raharjo

Hipertensi di Puskesmas Kedungmundu meningkat dari tahun ke tahun. Tujuan penelitian ini adalah untuk mengetahui faktor risiko yang berhubungan dengan kejadian hipertensi usia produktif (25-54 tahun) di wilayah kerja Puskesmas Kedungmundu tahun 2013. Jenis penelitian ini adalah survey analitik dengan pendekatan case control. Sampel berjumlah 30 orang pada masing-masing kelompok kasus dan kontrol yang diambil dengan teknik accidental sampling. Analisis data menggunakan uji chi square dengan derajat kemaknaan (α) = 0,05. Hasil penelitian menunjukkan bahwa faktor risiko yang berhubungan dengan hipertensi usia produktif (25-54 tahun)  adalah faktor genetik (p value=0,019, OR=4,125), obesitas (p value=0038, OR=3,5), kebiasaan merokok (p value=0,017, OR=6,0), konsumsi garam (p value=0,004, OR=5,675), penggunaan minyak jelantah (p value=0,009, OR=4,929) dan stress psikis (p value=0,002, OR=6,417). Variabel yang tidak berhubungan adalah aktifitas fisik (p value=0,065), konsumsi alkohol (p value=0,148), jenis pekerjaan (p value=0,333), pendapatan keluarga (p value=0,531) lama kerja (p value=0,588). Saran bagi penderita hipertensi usia produktif (25-54 tahun) di Kedungmundu supaya lebih meningkatkan status kesehatan dengan lebih teratur memeriksakan kesehatannya, khususnya tekanan darah. Bagi Puskesmas untuk meningkatkan pengetahuan masyarakat tentang hipertensi. Bagi peneliti lain untuk menambah faktor risiko lain yang berhubungan dengan hipertensi usia produktif. Hypertension  at Kedungmundu Puskesmas was ascending from year to year. The purpose of this study is to find risk factors which related to the Hypertension productive age (25-54 years) at working area health centers Kedungmundu Year 2013. This is a research of analytical survey with casecontrol approach. Sample of 30 people in each case group and controlgroup who were taken using accidental sampling technique. Data analysis using chi square test with degrees of significance (α) = 0,05. The study results show that the risk factor which related to the Hypertension productive age (25-54 years) genetic factor  (p value=0,019, OR=4,125), obesity (p value=0,038, OR=3,5), smooking habit (p value=0,017, OR=6,0), salt consumption (p value=0,004, OR=5,675), use jelantah oil (p value=0,009, OR=4,929) and psychological stress (p value=0,002, OR=6,417). The risk factor which are not related are physical activities (p value=0,065), alcohol consumption (p value=0,148), type of work (p value=0,333), family’s income (p value=0,531) and duration of employment (p value=0,588). The advice to patient hypertension productive age (25-54 tahun) at Kedungmundu to improve their health status by having themselves checked on more regular basis, particularly for their blood pressure. For the public health center to improve knowledge of the hypertension to the public. For the other researcher could find out another risk factors relate to the hypertension.


2021 ◽  
Vol 2 (2) ◽  
pp. 88-96
Author(s):  
Rydwan Efendi ◽  
Yustini Alioes ◽  
Eni Rahmi

The increasing production of hormone estrogen and progesteron during pregnance known as a risk factors of periodontal disease during pregnance. The other risk factor of periodontal disease during pregnance is obesity, because adipose tissue in obesity person produce pro inflamatory cytokines that influence periodontal status. Both of this risk factors could happen in pregnance woman. During pregnancy, production of hormones estrogen, progesteron and the weight is gained. The aim of this study was to evaluate the relationship between weight during pregnance with periodontal status. This research was an observational analytic with crossectional comparative, with 52 sampels. CPI indeks was used to evaluate the periodontal status meanwhile weight during pregnance was measured by GWS IOM. The resulting data were analyzed by chi-square test. There were significantly differences between pregnance weight at trimester 2nd and 3rd with increasing of the Community Periodontal Indeks.


2013 ◽  
Vol 29 (7) ◽  
pp. 442-446 ◽  
Author(s):  
Fenghe Li ◽  
Xuehu Wang ◽  
Wen Huang ◽  
Wei Ren ◽  
Jun Cheng ◽  
...  

Objective The aim of our study is to investigate the prevalence of silent pulmonary embolism in patients with deep venous thrombosis in the lower limbs and to evaluate the associated risk factors. Methods A total of 322 patients with acute deep venous thrombosis confirmed by CT venography or Doppler ultrasonography were studied. The diagnosis of silent pulmonary embolism was established by computed tomography pulmonary arteriography (CTPA). The association between covariates and the prevalence of silent pulmonary embolism in patients with deep venous thrombosis in lower limbs were assessed using chi-square test and multivariable regression. Results The incidence of silent pulmonary embolism was 33.5% (108 in 322 patients) in all patients with deep venous thrombosis in lower limbs. Chi-square test showed male gender, the right lower limb, proximal location of the thrombus, unprovoked venous thrombosis and coexisting heart diseases were related to a higher incidence of silent pulmonary embolism in patients with deep venous thrombosis in lower limbs. The multivariate regression analysis confirmed that the risk factors associated with silent pulmonary embolism in deep venous thrombosis patients included the right side and proximal location of the thrombus (odds ratio: 2.023, 95% CI: 1.215–3.368; odds ratio: 3.610, 95% CI: 1.772–7.354), unprovoked venous thrombosis (odds ratio: 2.037, 95% CI: 1.188–3.493), coexisting heart diseases (odds ratio: 4.507, 95% CI: 2.667–7.618). Conclusion Silent pulmonary embolism occurred frequently in patients with deep venous thrombosis in lower limbs. The right side, the proximal location of the thrombus, unprovoked venous thrombosis and coexisting heart diseases increased the risk for the occurrence of silent pulmonary embolism.


2018 ◽  
Vol 18 (1) ◽  
pp. 36-41
Author(s):  
Ali Afaghi Gharamaleki ◽  
Seyyedreza Moaddab ◽  
Mojtaba Darbouy ◽  
Khalil Ansarin ◽  
Shahram Hanifian

Background: Republic of Azerbaijan and Iran are two neighboring countries with high amount of travelling between them, different rates of TB and its resistance. These relationships could complicate the controlling of tuberculosis programs. Objective: The study was conducted to determine the prevalence of tuberculosis (TB) resistance and its risk factors in the two geographically co-related regions. Method: A total of 119Mycobacterium tuberculosis isolates from the patients of the target regions (Azerbaijan Rep. and Tabriz, Iran) were examined at the Central Tuberculosis Laboratory in Tabriz, Iran. The cultures and drug susceptibility tests was performed on Lowenstein-Jensen. All the isolates were categorized by MIRU-VNTR molecular method into clustered and un-clustered groups. The clustering as well as demographic data were analyzed to determine the risk factors contributing to TB resistance. The categorical data about the TB resistance were compared using a chi square test. Results: 27.8 percent of isolates were resistant at least to one of the 1st line of anti-tuberculosis drugs. The prevalence of any drug resistance and MDR were 64.6 and 17.9 percent respectively for Azari isolates, where the rate of resistance to rifampin and isoniazid was higher than streptomycin and ethambutol. The corresponding figures for the isolates from Tabriz were 16.9 and 3.3 percent respectively. Conclusions: The results of this comparative and cross-sectional study showed statistically significant differences in TB resistance between the isolates from the patients of Azerbaijan Rep. and Iran. According to the results, the rate of resistance to RMP, INH, and MDR was higher in Azerbaijan; consequently, nationality could be regarded as a risk factor of MDR, resistance to RMP and INH but not to SM and ETB. Other studied parameters did not contribute to TB resistance. Bangladesh Journal of Medical Science Vol.18(1) 2019 p.36-41


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Jack S Bell ◽  
Benjamin D James ◽  
Saif Al-Chalabi ◽  
Lynne Sykes ◽  
Philip A Kalra ◽  
...  

Abstract Background Acute kidney injury (AKI) is a recognised complication of coronavirus disease 2019 (COVID-19), yet the reported incidence varies widely and the associated risk factors are poorly understood. Methods Data was collected on all adult patients who returned a positive COVID-19 swab while hospitalised at a large UK teaching hospital between 1st March 2020 and 3rd June 2020. Patients were stratified into community- and hospital-acquired AKI based on the timing of AKI onset. Results Out of the 448 eligible patients with COVID-19, 118 (26.3 %) recorded an AKI during their admission. Significant independent risk factors for community-acquired AKI were chronic kidney disease (CKD), diabetes, clinical frailty score and admission C-reactive protein (CRP), systolic blood pressure and respiratory rate. Similar risk factors were significant for hospital-acquired AKI including CKD and trough systolic blood pressure, peak heart rate, peak CRP and trough lymphocytes during admission. In addition, invasive mechanical ventilation was the most significant risk factor for hospital-acquired AKI (adjusted odds ratio 9.1, p < 0.0001) while atrial fibrillation conferred a protective effect (adjusted odds ratio 0.29, p < 0.0209). Mortality was significantly higher for patients who had an AKI compared to those who didn’t have an AKI (54.3 % vs. 29.4 % respectively, p < 0.0001). On Cox regression, hospital-acquired AKI was significantly associated with mortality (adjusted hazard ratio 4.64, p < 0.0001) while community-acquired AKI was not. Conclusions AKI occurred in over a quarter of our hospitalised COVID-19 patients. Community- and hospital-acquired AKI have many shared risk factors which appear to converge on a pre-renal mechanism of injury. Hospital- but not community acquired AKI was a significant risk factor for death.


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