scholarly journals CHOLESTEROL AND CHOLESTEROL ESTER IN THE BLOOD SERUM OF CATTLE LATE IN PREGNANCY AND DURING THE EARLY LACTATION PERIOD

1928 ◽  
Vol 48 (1) ◽  
pp. 25-30 ◽  
Author(s):  
Richard E. Shope ◽  
John W. Gowen

1. The total cholesterol and cholesterol ester of bovine blood serum during the "dry" period of late pregnancy is low. 2. Following parturition the total cholesterol and cholesterol ester of bovine blood serum show a still greater, very transient decrease followed by a gradual rise to reach a rather constant level 40 to 50 days post partum. This lactation level is very much higher than the "dry" level.

2019 ◽  
Vol 73 (1) ◽  
pp. 10-16
Author(s):  
Radojica Djokovic ◽  
Marko Cincovic ◽  
Vladimir Kurcubic ◽  
Zoran Ilic ◽  
Milun Petrovic ◽  
...  

Introduction. The aim of this study was to determine and compare levels of blood serum calcium, inorganic phosphorus and magnesium in the peripartal period and during mid lactation in Holstein dairy cattle. Materials and Methods. Blood samples were collected from 12 cows in late pregnancy, 12 early lactation cows, and 12 mid lactation cows. Results and Conclusions. Serum calcium and inorganic phosphorus in blood of dairy cows in early and mid lactation were significantly lower compared to the values in the blood serum of dairy cows in late pregnancy, probably indicating the increased use of these macro elements by the mammary gland at the early stages of lactation. When the cows were in the lactation period, blood serum magnesium levels were significantly lower compared to the values of dairy cows during late pregnancy, probably indicating the increased use of magnesium by the dairy cows during lactation. The results show that the homeostasis of the macro elements examined in the blood of transition and mid lactation dairy cows was maintained, suggesting their adequate supply from alimentary sources.


1997 ◽  
Vol 1997 ◽  
pp. 94-94
Author(s):  
J.M. Moorby ◽  
S. Miles ◽  
R.T. Evans ◽  
W.J. Fisher ◽  
D.W.R. Davies

Increases in yields of milk and milk protein have been observed from dairy cows offered a high protein supplement during the dry period (Van Saun, Idleman and Sniffen, 1993; Moorby, Dewhurst and Marsden, 1996). One possible mechanism for this is an accumulation of maternal body protein during late pregnancy and its later release during lactation. This experiment was designed to investigate the effect of diet on the potential of dairy cows to accumulate and release body nitrogen over the course of the dry period and the first 20 weeks of lactation.Twelve multiparous Holstein-Friesian cows were offered one of three diets for 6 weeks prior to calving, with 4 animals per diet, in an continuous design experiment. Animals were offered ad libitum access to A) grass silage only (medium protein), B) a grass silage/barley straw mix (60:40 on a dry matter basis) (low protein), or C) grass silage plus 0.5 kg/d high protein maize gluten meal (high protein). After calving, all animals were offered a standard lactation diet based on ad libitum grass silage plus 10 kg/d concentrate to week 12 of lactation, with 7 kg/d thereafter. Animals were housed in individual stalls for 6 d N-balance procedures on three separate occasions in two groups of six animals: during the dry period (at approximately 3 to 4 weeks before calving), early-lactation (weeks 7 to 8 after calving) and mid-lactation (weeks 17 to 18).


1995 ◽  
Vol 60 (1) ◽  
pp. 99-107 ◽  
Author(s):  
I. Tauveron ◽  
E. Debras ◽  
S. Tesseraud ◽  
Y. Bonnet ◽  
Ph. Thiéblot ◽  
...  

AbstractThe present experiment was undertaken to investigate adaptations to insulin action on metabolism during lactation by using plasma concentrations of β hydroxybutyrate (β OH) free fatty acids (FFA) and lactate (L) as indicators. The study included three groups each of four goats. One group was used at 12 to 31 days post partum (early lactation), one group at 98 to 143 days post partum (mid lactation) and one group at 1 year post partum (dry period). For a given physiological state, each goat was examined four times to study the effect of insulin infused for 2·5 h at two rates, medium (0·36 nmol/min) followed by high (1·79 nmol/min) in two protocols: under normal aminoacidaemia in study 1 followed by hyperaminoacidaemia in study 2. Appropriate amino acid infusions were used to blunt insulin-induced hypoaminoacidaemia under eukaliaemic and euglycaemic clamp conditions or to create hyperaminoacidaemia and maintain this state under insulin treatment. In the basal state βOH (P < 0·05), mid lactation) and FFA (P < 0·05 early lactation) were higher during lactation than in the dry period. Plasma L was unmodified. Insulin infusion always resulted in a decrease in βOH levels (P < 0·05). In both studies, the change in βOH concentration as a function of changes in plasma insulin (an index of insulin sensitivity) was greater during early lactation than in the dry period (P < 0·05); this was also the case of mid lactation in study 1. Insulin infusion decreased plasma FFA during early lactation and in the dry period in study 1 (P < 0·05), and there was a trend for insulin sensitivity to be greater during early lactation. In both studies insulin infusion did not affect plasma L in lactating goats whereas plasma L was increased in dry animals (P < 0·05). The results demonstrate that during early lactation, compared with the dry period, there is an increased ability of insulin to lower βOH and FFA concentrations. These effects were not altered by increasing plasma amino acid concentrations during insulin infusion.


2002 ◽  
Vol 53 (7) ◽  
pp. 737 ◽  
Author(s):  
C. R. Stockdale ◽  
J. R. Roche

This review considers the current literature on the energy and protein nutrition of dry cows and its subsequent impact on early lactation performance. Energy intake close to calving appears to be critical to events that occur post-partum, such that a key objective of dry cow feeding should be to maximise or maintain feed intake immediately prior to calving, or at least to minimise the decline in intake. Although a decline in dry matter intake seems to be a normal adaptive event in peri-parturient ruminants, it is the magnitude and duration of the decline that are of concern. Most research has been undertaken using total mixed rations or conserved forage and concentrates, where a wide range of quantities and types of feeds have been used. However, no clear conclusions can be drawn regarding optimum levels of feeding, types of forage, or proportions of concentrates that should be fed to cows in the late dry period to minimise the intake decline. The importance of maintaining energy intake is associated with the reduction of the incidence and severity of metabolic diseases post-partum, by reducing triglyceride mobilisation from adipose tissue, and preventing excessive depletion of hepatic glycogen levels.


2008 ◽  
Vol 62 (1-2) ◽  
pp. 3-12 ◽  
Author(s):  
Horea Samanc ◽  
Velibor Stojic ◽  
Danijela Kirovski ◽  
Milijan Jovanovic ◽  
Horia Cernescu ◽  
...  

The aim of this study was to investigate the influence of energy status of cows, estimated by body condition score, on the incidence and the degree of hepatic lipidosis during the early stage of lactation. Cows were divided into four groups: dry, early puerperal, early lactation and late lactation period. Each group consisted of 60 cows. Body condition was scored by the method established in Elaco Animal Health Buletin Al 8478. According to this method, body condition score is represented numerically from 1 to 5 points. Liver samples for pathohistological analyses were taken by biopsy from early lactation cows (60. day of lactation). Fat content in hepatocytes was determined morphometrically and results were compared with criteria based on total lipid and triglyceride content in liver tissue. On farm A, average body condition scores were in a range from 3.31, at sixty days of lactation, to 3.86 points in the dry period. Nevertheless, the range was wider on farm B, and was from 2.18 points at sixty days of lactation to 4.15 points at the dry period. Besides, differences in average body condition scores were higher than 1 point, and in some cases (between late lactation or dry period to sixty days of lactation) were almost 2 points. The incidence and the degree of hepatic lipidosis strongly differ between the two examined farms. On farm A the incidence of hepatic lipidosis was 18.33 percent, while on farm B that percent was much higher (43.32). A significant difference was established in the degree of hepatic lipidosis between those two farms. On farm A diffuse hepatic lipidosis was determined in 5.0 percent of cows, while on farm B that percent was 18.33. According to these results, most of the cows on farm B had uncontrolled lipomobilisation and severe fatty liver during the early lactation period, probably due to the obesity of these cows in late lactation and the dry period.


2019 ◽  
Vol 88 (2) ◽  
pp. 143-155
Author(s):  
Maja Došenović Marinković ◽  
Branislava Belić ◽  
Marko R. Cincović ◽  
Radojica Đoković ◽  
Ivana Lakić ◽  
...  

The aim of this study was to determine to relationship between glucose, insulin, non-esterified fatty acid (NEFA) and indices of insulin resistance in the dry period (DP) and early lactation (EL). The importance of this study was in determining the relation between insulin sensitivity in DP and insulin resistance in EL. A total of 30 normally fed Holstein-Friesian cows with a high body condition score (> 3.75) were included in the study. Blood samples were collected in DP (weeks 5-7 ante partum) and EL (weeks 1-2 post partum). Cows in EL showed higher insulin resistance in comparison to DP due to a lower concentration of glucose and insulin, higher concentration of NEFA, lower value of revised quantitative insulin sensitivity check index and higher values of glucose:insulin and NEFA:insulin ratios (lower pancreas responsivnes to glucose and antilipolytic effect of insulin). Higher concentrations of insulin and glucose in the DP lead to a decrease in their concentrations and an increase in glucose:insulin and NEFA:insulin ratios in the EL. The revised quantitative insulin sensitivity check index in DP negatively correlates with the same index in EL, while positively correlating with the NEFA and NEFA:insulin ratio in EL. The EL revised quantitative insulin sensitivity check index value was influenced by dynamic changes (DP minus EL) in the insulin, NEFA, and glucose concentrations. The relationship between the indicators shows that higher insulin sensitivity in the DP increases resistance in EL in normally fed obese dairy cows.


2010 ◽  
Vol 26 (5-6) ◽  
pp. 309-318
Author(s):  
Z. Novakovic ◽  
Lj. Sretenovic ◽  
S. Aleksic ◽  
M.M. Petrovic ◽  
V. Pantelic ◽  
...  

Condition of animals is manifested through level of achieved nourishment. Body condition score (BCS) is a precise method of determination of reserves of deposited energy in form of subcutaneous fat tissue. Adequate body reserves are necessary requirement for maximal increase of milk production in the period of early lactation. Based on BCS we can precisely determine the number of cows which are bellow weight (excessively thin) or over weight (excessively fat). Body condition changes during lactation. Cows in early lactation are in the negative energy balance (NEB). Changes of the body condition should be over at the end of lactation. Objective is to have cows in optimal body condition during all production phases. Object of research was body condition of high yielding cows during production cycle. Realized sample size was 363 cows of Holstein-Friesian breed. Average BCS value of cows in dry period was 3.39 (2.37-4.41), at calving 3.56 (2.55-4.63), at lactation peak 2.30 (1.35-3.16) and in the mid lactation 2.50 (1.35-3.43). In dry period, most of cows (n=100 or 27.55%) ranged in BCS from 3.26 to 3.50. During dry period increase of body condition scores of cows occurred. At calving, most of heads (n=99 or 27.50%) ranged in their BCS from 3.51 to 3.75. During period of early lactation there was a significant decrease of the body condition of cows. At the peak of lactation a slight increase of body condition was recorded. At the peak of lactation, most cows (n=125 or 36.76%) ranged in BCS from 2.26 to 2.50. In the mid-lactation period, slight increase of body condition of cows occurred. During this period, most cows (n=88 or 27.32%) ranged in their BCS from 2.51 to 2.75. In general, realized average BCS results according to production phases deviated statistically significantly from target values.


2016 ◽  
Vol 32 (1) ◽  
pp. 9-14 ◽  
Author(s):  
Milorad Krsmanovic ◽  
Radojica Djokovic ◽  
Marko Cincovic ◽  
Dusica Ostojic-Andric ◽  
Jovan Bojkovski

This study examined the activities of aspartate-aminotransferase (AST), gamma-glutamyl-transferase (GGT) and lactate-dehydrogenase (LDH) in the blood serum of 45 dairy Simmental cows divided into three groups according to production period. The first group (n=15) consisted of late pregnant dairy cows, the second group (n=15) cows in the early lactation, and the third group (n=15) cow in mid lactation. The significant higher activity (P<0.05) of AST, GGT and LDH were determined in the early lactation period than in dry period and during full lactation. Research results showed possibility of mild degree of hepatic lesions, probably due to fat infiltration in early lactation cows. Serum AST enzyme activities were significant correlated (P<0.05) with GGT and LDH activities and may be most sensitive indicator.


1971 ◽  
Vol 13 (1) ◽  
pp. 107-116 ◽  
Author(s):  
R. Marsh ◽  
M. K. Curran ◽  
R. C. Campling

SUMMARY1. Effects of late pregnancy and early lactation on the voluntary intake of dried grass (Expt 1) and a poor quality seeds hay (Expt 2) by dairy cows are described. Each cow received a constant daily allocation of concentrates throughout late pregnancy. After calving half the cows received an 80% increase in concentrates, and the remainder continued to receive their pre-partum allowance.2. Mean daily intakes of dried grass were higher than those of poor quality seeds hay. Intake of dried grass in week 2 of lactation was significantly correlated with the live weight of the cows, but a non-significant correlation was observed when seeds hay was offered.3. During late pregnancy mean daily intakes of both roughages were approximately constant until the week immediately before par turition, when a significant decline occurred.4. After calving mean daily intakes of both roughages increased throughout the first six weeks of lactation by 20–30% of the intake at week 1 post partum.5. The 80% increase in daily concentrate allocation in early lactation caused a significant decline of 0·55 kg dried grass dry-matter intake per kg concentrate dry matter; the decline of 0·17 kg poor quality hay dry matter per kg concentrate dry matter was not significant.


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